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TW200420287A - Propofol-containing fat emulsions - Google Patents

Propofol-containing fat emulsions

Info

Publication number
TW200420287A
TW200420287A TW092134251A TW92134251A TW200420287A TW 200420287 A TW200420287 A TW 200420287A TW 092134251 A TW092134251 A TW 092134251A TW 92134251 A TW92134251 A TW 92134251A TW 200420287 A TW200420287 A TW 200420287A
Authority
TW
Taiwan
Prior art keywords
propofol
containing fat
fat emulsion
fat emulsions
phosphatidylglycerol
Prior art date
Application number
TW092134251A
Other languages
English (en)
Inventor
Kenji Matsuda
Koichi Takeda
Toshimitsu Terao
Tadaaki Inoue
Original Assignee
Otsuka Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Otsuka Pharma Co Ltd filed Critical Otsuka Pharma Co Ltd
Publication of TW200420287A publication Critical patent/TW200420287A/zh

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/05—Phenols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A61P23/02—Local anaesthetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dispersion Chemistry (AREA)
  • Dermatology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
TW092134251A 2002-12-06 2003-12-04 Propofol-containing fat emulsions TW200420287A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2002355880 2002-12-06

Publications (1)

Publication Number Publication Date
TW200420287A true TW200420287A (en) 2004-10-16

Family

ID=32500805

Family Applications (1)

Application Number Title Priority Date Filing Date
TW092134251A TW200420287A (en) 2002-12-06 2003-12-04 Propofol-containing fat emulsions

Country Status (10)

Country Link
US (1) US20060134145A1 (zh)
EP (1) EP1576953A4 (zh)
JP (1) JPWO2004052354A1 (zh)
KR (1) KR20050084178A (zh)
CN (1) CN100367943C (zh)
AU (1) AU2003289163A1 (zh)
CA (1) CA2508441A1 (zh)
RU (1) RU2335279C2 (zh)
TW (1) TW200420287A (zh)
WO (1) WO2004052354A1 (zh)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101155580A (zh) 2005-04-13 2008-04-02 株式会社大塚制药工场 含异丙酚的脂肪乳剂
MY147790A (en) * 2005-04-28 2013-01-31 Takeda Pharmaceutical Stable emulsion composition
EP2010150A2 (en) * 2006-04-20 2009-01-07 Amgen Inc. Stable emulsion formulations
WO2008023384A1 (en) * 2006-08-24 2008-02-28 Bharat Serums & Vaccines Ltd. Propofol emulsion compositions for intravenous administration
JP5193870B2 (ja) 2006-09-05 2013-05-08 キユーピー株式会社 プロスタグランジン脂肪乳剤およびその製造方法、ならびにその安定化方法および乳化剤
ES2390252T3 (es) * 2008-08-11 2012-11-08 Koninklijke Philips Electronics N.V. Técnicas de ciclo de servicio en protocolos de control de acceso al medio (MAC) para redes de área corporal
DE102009003980A1 (de) 2009-01-07 2010-07-08 B. Braun Melsungen Ag Propofol in triheptanoinhaltiger Trägeremulsion
JP5591603B2 (ja) * 2010-05-21 2014-09-17 富士フイルム株式会社 プロポフォール含有水中油型エマルション組成物
JP2012012331A (ja) * 2010-06-30 2012-01-19 Fujifilm Corp プロポフォール含有水中油型エマルション組成物
CN102370619A (zh) * 2010-08-18 2012-03-14 罗和国 脂肪乳乳化局麻药
CN101926757B (zh) 2010-09-01 2013-01-02 北京大学 一种难溶性药物的液体组合物及其制备方法
JP5759804B2 (ja) * 2011-06-27 2015-08-05 富士フイルム株式会社 容器詰製剤
CN102366404B (zh) * 2011-10-20 2015-10-07 四川百利药业有限责任公司 一种丙泊酚中/长链脂肪乳剂
FR2983731B1 (fr) * 2011-12-07 2014-04-25 Univ Paris Descartes Emulsions topiques a base de melanges eutectiques d'anesthesiques locaux et d'acide gras
US11219606B2 (en) 2013-10-11 2022-01-11 University Of Florida Research Foundation, Inc. Method of manufacturing stable emulsions and compositions containing the same
CN105310976B (zh) * 2014-06-04 2018-08-21 北京蓝丹医药科技有限公司 一种稳定的前列地尔组合物
MX2019010289A (es) * 2017-03-06 2019-10-21 Maruishi Pharma Composicion en emulsion acida que contiene anestesico local.
CN109985001A (zh) * 2017-12-29 2019-07-09 北京蓝丹医药科技有限公司 一种注射用营养型脂肪乳及其制备方法
CN109223712B (zh) * 2018-10-10 2020-06-02 武汉大安制药有限公司 氟比洛芬酯注射用乳剂及其制备方法
CN110368362B (zh) * 2019-08-01 2022-10-04 聊城大学 一种磷脂酰丝氨酸乳剂的制备方法
US11992483B2 (en) * 2021-03-31 2024-05-28 Cali Biosciences Us, Llc Emulsions for local anesthetics

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9605549D0 (en) * 1996-03-15 1996-05-15 Cambridge Consultants Container
US5637625A (en) * 1996-03-19 1997-06-10 Research Triangle Pharmaceuticals Ltd. Propofol microdroplet formulations
ES2252780T3 (es) * 1996-08-22 2006-05-16 Jagotec Ag Composiciones que comprenden microparticulas de sustancias insolubles en agua y metodo para su preparacion.
US6090800A (en) * 1997-05-06 2000-07-18 Imarx Pharmaceutical Corp. Lipid soluble steroid prodrugs
IL141095A0 (en) * 1998-08-19 2002-02-10 Rtp Pharma Inc Injectable aqueous dispersions of propofol
US6267985B1 (en) * 1999-06-30 2001-07-31 Lipocine Inc. Clear oil-containing pharmaceutical compositions
AU763945B2 (en) * 1999-06-04 2003-08-07 Skyepharma Inc. Oil-core compositions for the sustained release of hydrophobic drugs
TW422706B (en) * 1999-07-01 2001-02-21 Wang Iz Rung An oil-in-water emulsion type of paclitaxel
US20010047162A1 (en) * 2000-02-17 2001-11-29 Yasumi Yugari Injection kit and injection device
JP4865183B2 (ja) * 2000-06-06 2012-02-01 レキオファーマ株式会社 病変異常組織治療用医薬組成物キット
WO2001097779A2 (en) 2000-06-16 2001-12-27 Rtp Pharma Inc. Improved injectable dispersions of propofol
JP2002179562A (ja) * 2000-12-14 2002-06-26 Towa Yakuhin Kk 安定な静注用無痛プロポフォール脂肪乳剤

Also Published As

Publication number Publication date
RU2005121269A (ru) 2006-01-20
CN1720031A (zh) 2006-01-11
AU2003289163A1 (en) 2004-06-30
EP1576953A4 (en) 2008-08-06
EP1576953A1 (en) 2005-09-21
WO2004052354A1 (ja) 2004-06-24
CN100367943C (zh) 2008-02-13
KR20050084178A (ko) 2005-08-26
JPWO2004052354A1 (ja) 2006-04-06
RU2335279C2 (ru) 2008-10-10
US20060134145A1 (en) 2006-06-22
CA2508441A1 (en) 2004-06-24

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