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TR201819340T4 - IB-QX Benzeri Suşlardan Türetilmiş Enfeksiyöz Bronşit Aşıları - Google Patents

IB-QX Benzeri Suşlardan Türetilmiş Enfeksiyöz Bronşit Aşıları Download PDF

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Publication number
TR201819340T4
TR201819340T4 TR2018/19340T TR201819340T TR201819340T4 TR 201819340 T4 TR201819340 T4 TR 201819340T4 TR 2018/19340 T TR2018/19340 T TR 2018/19340T TR 201819340 T TR201819340 T TR 201819340T TR 201819340 T4 TR201819340 T4 TR 201819340T4
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TR
Turkey
Prior art keywords
viruses
infectious bronchitis
strains
vaccines derived
attenuated
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Application number
TR2018/19340T
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English (en)
Inventor
Harmen Geerligs Jacob
Aleida Cindy Meinders Maria
Geert Boelm Jan
Geertruida Bastiana Stuurman Elisabeth
Original Assignee
Zoetis Services Llc
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Publication date
Application filed by Zoetis Services Llc filed Critical Zoetis Services Llc
Publication of TR201819340T4 publication Critical patent/TR201819340T4/tr

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    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • C12N7/04—Inactivation or attenuation; Producing viral sub-units
    • C12N7/08—Inactivation or attenuation by serial passage of virus
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/215—Coronaviridae, e.g. avian infectious bronchitis virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/10—Expectorants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
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    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5254—Virus avirulent or attenuated
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A61K2039/541—Mucosal route
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
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    • A61K2039/544—Mucosal route to the airways
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • A61K2039/552—Veterinary vaccine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • C12N2770/20011—Coronaviridae
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    • C12N2770/00011—Details
    • C12N2770/20011—Coronaviridae
    • C12N2770/20061—Methods of inactivation or attenuation
    • C12N2770/20064—Methods of inactivation or attenuation by serial passage

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
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  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
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  • Communicable Diseases (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Pulmonology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Biotechnology (AREA)
  • Oncology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Mevcut buluş, IB-QX olarak bilinen son zamanlarda tanımlanmış bir IB virüsü genotipinden veya IB-QX ile genetik olarak alakalı virüslerden türetilmiş, burada IB-QX benzeri virüsler olarak anılan enfeksiyöz bronşit (IB) virüsleri ile ilgilidir. Buluşa ait IB virüsleri, canlı ve atenüe veya eylemsizleştirilmiş olabilir. Buluşa ait canlı, atenüe IB virüsleri, bir IB-QX benzeri virüsün seri olarak nesil atlatılmasıyla üretilebilir. Buluşa ait IB virüsleri, diğerleri arasında, IB-QX ve IB­QX benzeri virüslere karşı aşılar için faydalıdır. Şimdiye dek bilinen IB virüsleri aşı suşlarının, IB-QX ve IB-QX benzeri virüslerin neden olduğu enfeksiyöz bronşite karşı koruma sağlamada yetersiz olduğu kanıtlanmıştı.
TR2018/19340T 2008-08-08 2009-08-07 IB-QX Benzeri Suşlardan Türetilmiş Enfeksiyöz Bronşit Aşıları TR201819340T4 (tr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US8722808P 2008-08-08 2008-08-08

Publications (1)

Publication Number Publication Date
TR201819340T4 true TR201819340T4 (tr) 2019-01-21

Family

ID=41211689

Family Applications (1)

Application Number Title Priority Date Filing Date
TR2018/19340T TR201819340T4 (tr) 2008-08-08 2009-08-07 IB-QX Benzeri Suşlardan Türetilmiş Enfeksiyöz Bronşit Aşıları

Country Status (26)

Country Link
US (1) US9296991B2 (tr)
EP (1) EP2331682B1 (tr)
JP (3) JP2011530294A (tr)
KR (2) KR20110038181A (tr)
CN (1) CN102239252B (tr)
AR (1) AR072976A1 (tr)
AU (1) AU2009279528A1 (tr)
BR (1) BRPI0917447A2 (tr)
CA (1) CA2732822C (tr)
CL (1) CL2011000262A1 (tr)
CO (1) CO6351810A2 (tr)
CY (1) CY1121567T1 (tr)
DK (1) DK2331682T3 (tr)
ES (1) ES2702089T3 (tr)
HU (1) HUE041481T2 (tr)
LT (1) LT2331682T (tr)
ME (1) ME01270B (tr)
MX (1) MX339731B (tr)
PL (1) PL2331682T3 (tr)
PT (1) PT2331682T (tr)
RU (1) RU2568053C2 (tr)
SI (1) SI2331682T1 (tr)
TR (1) TR201819340T4 (tr)
UA (1) UA103330C2 (tr)
WO (1) WO2010017440A1 (tr)
ZA (1) ZA201100849B (tr)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI616535B (zh) * 2012-12-18 2018-03-01 梅里亞有限公司 Ｉｂｖ、ｃｓｆｖ及ｎｄｖ之高解析度熔解基因型比對
CN103028112B (zh) * 2012-12-31 2014-08-06 青岛易邦生物工程有限公司 一种鸡新城疫和传染性支气管炎二联活疫苗
CN103146654B (zh) * 2013-03-25 2014-07-30 浙江诺倍威生物技术有限公司 一株人工弱化的鸡传染性支气管炎病毒及其应用
KR20210068602A (ko) 2016-06-02 2021-06-09 조에티스 서비시즈 엘엘씨 감염성 기관지염에 대한 백신
CN108950068B (zh) * 2018-07-18 2021-05-07 浙江大学 一种鸡传染性支气管炎病毒qx型毒株鉴别检测试剂盒
EP3873516A1 (en) * 2018-10-31 2021-09-08 Boehringer Ingelheim Vetmedica GmbH 4/91 ibv vaccine with heterologous spike protein
EP4560014A4 (en) * 2022-07-22 2025-10-29 Khav Co Ltd ATTENUATED STRAIN OF THE AVIAN INFECTIOUS BRONCHITIS VIRUS AND VACCINE COMPOSITION CONTAINING IT
KR102717877B1 (ko) * 2023-06-16 2024-10-16 주식회사 지나이너 외래 qx 유사 바이러스 스파이크 단백질을 포함하는 전염성 기관지염 키메라 바이러스 및 이를 포함하는 백신 조성물
WO2025055902A1 (en) * 2023-09-11 2025-03-20 Boehringer Ingelheim Vetmedica (China) Co., Ltd. Attenuated infectious bronchitis virus and a vaccine comprising the same
GB2640725A (en) * 2024-05-03 2025-11-05 Genera Dionicko Drustvo Vaccine
CN118546258B (zh) * 2024-06-03 2024-11-29 中国动物卫生与流行病学中心 一种鸡传染性支气管炎病毒抗原表位融合肽及其在间接elisa检测中的应用

Family Cites Families (7)

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US4867975A (en) * 1988-01-27 1989-09-19 University Of Delaware Live attenuated temperature-sensitive avian infectious bronchitis virus vaccines and preparation and use thereof
US5037650A (en) * 1988-03-08 1991-08-06 Akzo N.V. Live combination vaccine
PT639640E (pt) 1993-07-30 2001-03-30 Akzo Nobel Nv Vacina para aves domesticas com infeccoes provocadas pela estirpe 4/91 do virus da bronquite
JPH07206705A (ja) * 1993-11-03 1995-08-08 American Cyanamid Co 生インオボ（ｉｎ ｏｖｏ）ワクチン
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Also Published As

Publication number Publication date
CL2011000262A1 (es) 2011-05-06
CY1121567T1 (el) 2020-05-29
ES2702089T3 (es) 2019-02-27
SI2331682T1 (sl) 2019-01-31
ZA201100849B (en) 2015-10-28
PL2331682T3 (pl) 2019-03-29
JP2015144605A (ja) 2015-08-13
ME01270B (me) 2013-06-20
CN102239252A (zh) 2011-11-09
MX339731B (es) 2016-06-08
EP2331682A1 (en) 2011-06-15
US9296991B2 (en) 2016-03-29
UA103330C2 (ru) 2013-10-10
US20110305726A1 (en) 2011-12-15
CA2732822A1 (en) 2010-02-11
DK2331682T3 (en) 2018-12-10
JP6397539B2 (ja) 2018-09-26
KR101732240B1 (ko) 2017-05-02
CO6351810A2 (es) 2011-12-20
LT2331682T (lt) 2018-12-10
MX2011001514A (es) 2011-03-29
AU2009279528A1 (en) 2010-02-11
AR072976A1 (es) 2010-10-06
KR20110038181A (ko) 2011-04-13
HUE041481T2 (hu) 2019-05-28
WO2010017440A1 (en) 2010-02-11
PT2331682T (pt) 2018-12-19
HK1159164A1 (zh) 2012-07-27
EP2331682B1 (en) 2018-10-24
JP2011530294A (ja) 2011-12-22
CN102239252B (zh) 2015-04-15
BRPI0917447A2 (pt) 2015-12-01
CA2732822C (en) 2016-09-20
RU2568053C2 (ru) 2015-11-10
KR20150020623A (ko) 2015-02-26
RU2011104201A (ru) 2012-08-20
JP2017212976A (ja) 2017-12-07

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