TR201721824A2 - A MODIFIED EMISSION COMBINATION CONTAINING LINAGLIPTIN AND METFORMIN - Google Patents
A MODIFIED EMISSION COMBINATION CONTAINING LINAGLIPTIN AND METFORMIN Download PDFInfo
- Publication number
- TR201721824A2 TR201721824A2 TR2017/21824A TR201721824A TR201721824A2 TR 201721824 A2 TR201721824 A2 TR 201721824A2 TR 2017/21824 A TR2017/21824 A TR 2017/21824A TR 201721824 A TR201721824 A TR 201721824A TR 201721824 A2 TR201721824 A2 TR 201721824A2
- Authority
- TR
- Turkey
- Prior art keywords
- metformin
- combination containing
- linagliptin
- emission combination
- modified emission
- Prior art date
Links
- LTXREWYXXSTFRX-QGZVFWFLSA-N Linagliptin Chemical compound N=1C=2N(C)C(=O)N(CC=3N=C4C=CC=CC4=C(C)N=3)C(=O)C=2N(CC#CC)C=1N1CCC[C@@H](N)C1 LTXREWYXXSTFRX-QGZVFWFLSA-N 0.000 title abstract 2
- 229960002397 linagliptin Drugs 0.000 title abstract 2
- XZWYZXLIPXDOLR-UHFFFAOYSA-N metformin Chemical compound CN(C)C(=N)NC(N)=N XZWYZXLIPXDOLR-UHFFFAOYSA-N 0.000 title abstract 2
- 229960003105 metformin Drugs 0.000 title abstract 2
- 238000009472 formulation Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000007916 tablet composition Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
- A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A61K31/52—Purines, e.g. adenine
- A61K31/522—Purines, e.g. adenine having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
Abstract
Mevcut buluş, linagliptin, metformin ve en az bir modifiye salım sağlayan ajan içeren farmasötik tablet formülasyonu ile ilgilidir. Ayrıca mevcut buluş, söz konusu formülasyonu hazırlama yöntemi de sunmaktadır.The present invention relates to a pharmaceutical tablet formulation comprising linagliptin, metformin and at least one modified release agent. In addition, the present invention provides a method of preparing said formulation.
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| TR2017/21824A TR201721824A2 (en) | 2017-12-26 | 2017-12-26 | A MODIFIED EMISSION COMBINATION CONTAINING LINAGLIPTIN AND METFORMIN |
| PCT/TR2018/050870 WO2019132833A1 (en) | 2017-12-26 | 2018-12-24 | The modified release combination comprising linagliptin and metformin |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| TR2017/21824A TR201721824A2 (en) | 2017-12-26 | 2017-12-26 | A MODIFIED EMISSION COMBINATION CONTAINING LINAGLIPTIN AND METFORMIN |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TR201721824A2 true TR201721824A2 (en) | 2019-07-22 |
Family
ID=65444312
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TR2017/21824A TR201721824A2 (en) | 2017-12-26 | 2017-12-26 | A MODIFIED EMISSION COMBINATION CONTAINING LINAGLIPTIN AND METFORMIN |
Country Status (2)
| Country | Link |
|---|---|
| TR (1) | TR201721824A2 (en) |
| WO (1) | WO2019132833A1 (en) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2023163510A1 (en) * | 2022-02-23 | 2023-08-31 | 주식회사 제뉴원사이언스 | Pharmaceutical complex formulation with controlled drug release comprising linagliptin or pharmaceutically acceptable salt thereof and metformin or pharmaceutically acceptable salt thereof |
| EP4548913A1 (en) * | 2023-11-06 | 2025-05-07 | Genepharm S.A. | A monolayer tablet of linagliptin and metformin |
| WO2025157944A1 (en) * | 2024-01-23 | 2025-07-31 | Genepharm S.A. | A tablet of linagliptin and metformin |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2011295837B2 (en) * | 2010-09-03 | 2015-06-18 | Astrazeneca Uk Limited | Drug formulations using water soluble antioxidants |
| UY33937A (en) * | 2011-03-07 | 2012-09-28 | Boehringer Ingelheim Int | PHARMACEUTICAL COMPOSITIONS CONTAINING DPP-4 AND / OR SGLT-2 AND METFORMIN INHIBITORS |
| IN2013MU03847A (en) * | 2013-12-09 | 2015-07-24 | Intas Pharmaceuticals Ltd | |
| US20160106677A1 (en) * | 2014-10-17 | 2016-04-21 | Boehringer Ingelheim International Gmbh | Pharmaceutical composition and uses thereof |
| KR101526825B1 (en) * | 2014-12-23 | 2015-06-08 | 주식회사 한독 | Pharmaceutical Compositions for The Treatment of Diabetes |
| US20180344647A1 (en) | 2015-12-04 | 2018-12-06 | Boehringer Ingelheim International Gmbh | Pharmaceutical composition, methods for treating and uses thereof |
-
2017
- 2017-12-26 TR TR2017/21824A patent/TR201721824A2/en unknown
-
2018
- 2018-12-24 WO PCT/TR2018/050870 patent/WO2019132833A1/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| WO2019132833A1 (en) | 2019-07-04 |
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