TR201100148A2 - Stable acarbose formulations. - Google Patents
Stable acarbose formulations.Info
- Publication number
- TR201100148A2 TR201100148A2 TR2011/00148A TR201100148A TR201100148A2 TR 201100148 A2 TR201100148 A2 TR 201100148A2 TR 2011/00148 A TR2011/00148 A TR 2011/00148A TR 201100148 A TR201100148 A TR 201100148A TR 201100148 A2 TR201100148 A2 TR 201100148A2
- Authority
- TR
- Turkey
- Prior art keywords
- acarbose
- formulations
- stable
- adiposity
- hyperlipidemia
- Prior art date
Links
- XUFXOAAUWZOOIT-SXARVLRPSA-N (2R,3R,4R,5S,6R)-5-[[(2R,3R,4R,5S,6R)-5-[[(2R,3R,4S,5S,6R)-3,4-dihydroxy-6-methyl-5-[[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)-1-cyclohex-2-enyl]amino]-2-oxanyl]oxy]-3,4-dihydroxy-6-(hydroxymethyl)-2-oxanyl]oxy]-6-(hydroxymethyl)oxane-2,3,4-triol Chemical compound O([C@H]1O[C@H](CO)[C@H]([C@@H]([C@H]1O)O)O[C@H]1O[C@@H]([C@H]([C@H](O)[C@H]1O)N[C@@H]1[C@@H]([C@@H](O)[C@H](O)C(CO)=C1)O)C)[C@@H]1[C@@H](CO)O[C@@H](O)[C@H](O)[C@H]1O XUFXOAAUWZOOIT-SXARVLRPSA-N 0.000 title abstract 2
- 229960002632 acarbose Drugs 0.000 title abstract 2
- XUFXOAAUWZOOIT-UHFFFAOYSA-N acarviostatin I01 Natural products OC1C(O)C(NC2C(C(O)C(O)C(CO)=C2)O)C(C)OC1OC(C(C1O)O)C(CO)OC1OC1C(CO)OC(O)C(O)C1O XUFXOAAUWZOOIT-UHFFFAOYSA-N 0.000 title abstract 2
- 238000009472 formulation Methods 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 title abstract 2
- 208000031226 Hyperlipidaemia Diseases 0.000 abstract 1
- 206010012601 diabetes mellitus Diseases 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/702—Oligosaccharides, i.e. having three to five saccharide radicals attached to each other by glycosidic linkages
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
Mevcut buluş stabilite sorunu giderilmiş, akarboz içeren formülasyonlara ve bu formülasyonların diyabet, adipozite ve hiperlipidemide kullanımına yöneliktir.The present invention is directed to stabilized, acarbose-containing formulations and their use in diabetes, adiposity and hyperlipidemia.
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| TR2011/00148A TR201100148A2 (en) | 2011-01-06 | 2011-01-06 | Stable acarbose formulations. |
| PCT/TR2012/000004 WO2012093973A2 (en) | 2011-01-06 | 2012-01-06 | Stable acarbose formulations |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| TR2011/00148A TR201100148A2 (en) | 2011-01-06 | 2011-01-06 | Stable acarbose formulations. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TR201100148A2 true TR201100148A2 (en) | 2012-07-23 |
Family
ID=45879005
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TR2011/00148A TR201100148A2 (en) | 2011-01-06 | 2011-01-06 | Stable acarbose formulations. |
Country Status (2)
| Country | Link |
|---|---|
| TR (1) | TR201100148A2 (en) |
| WO (1) | WO2012093973A2 (en) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2014036528A2 (en) | 2012-08-31 | 2014-03-06 | Ixchel Pharma, Llc | Agents useful for treating obesity, diabetes and related disorders |
| EP3943076A3 (en) * | 2014-12-17 | 2022-04-13 | Empros Pharma AB | A modified release composition of orlistat and acarbose for the treatment of obesity and related metabolic disorders |
| CN104971080B (en) * | 2015-06-09 | 2018-12-28 | 中国科学院西北高原生物研究所 | Yellow bur reality polysaccharide improves the purposes of disorders of lipid metabolism |
| CN104983771B (en) * | 2015-06-09 | 2018-12-28 | 中国科学院西北高原生物研究所 | Yellow bur improves the purposes of disorders of lipid metabolism in fact |
| CN114053234A (en) * | 2021-12-29 | 2022-02-18 | 江苏省药物研究所有限公司 | Acarbose tablet and preparation method thereof |
| CN116650430A (en) * | 2023-07-18 | 2023-08-29 | 浙江乐普制药有限公司 | Acarbose tablet and preparation method thereof |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2347782C3 (en) | 1973-09-22 | 1979-10-11 | Bayer Ag, 5090 Leverkusen | Amino sugar derivatives, processes for their preparation and medicaments containing these compounds |
| DE3134591A1 (en) * | 1981-09-01 | 1983-03-10 | Bayer Ag, 5090 Leverkusen | NEW MEDICINE PREPARATIONS FOR GLYCOSIDE HYDROLASE INHIBITORS |
| JPH0739340A (en) | 1993-08-04 | 1995-02-10 | Shozo Shimizu | Method for preventing discoloration of foliage of japanese horseradish due to high-temperature heat sterilization |
| CA2128044C (en) * | 1993-08-05 | 2007-02-20 | Klaus-Dieter Bremer | Pharmaceutical compositions comprising a glucosidase and/or amylase inhibitor, and a lipase inhibitor |
| US20040081697A1 (en) * | 1998-11-12 | 2004-04-29 | Smithkline Beecham P.L.C. | Pharmaceutical composition for modified release of an insulin sensitiser and another antidiabetic agent |
| FR2834214B1 (en) * | 2001-12-28 | 2004-09-24 | Lipha | PHARMACEUTICAL COMPOSITION COMPRISING AN ALPHA-GLUCOSIDASE INHIBITOR AND 4-OXO-BUTANOIC ACID AND ITS USE FOR TREATING DIABETES |
| CN100464754C (en) * | 2007-03-12 | 2009-03-04 | 杭州中美华东制药有限公司 | Acarbose medicine composition and its prepn |
-
2011
- 2011-01-06 TR TR2011/00148A patent/TR201100148A2/en unknown
-
2012
- 2012-01-06 WO PCT/TR2012/000004 patent/WO2012093973A2/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| WO2012093973A3 (en) | 2012-10-18 |
| WO2012093973A2 (en) | 2012-07-12 |
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