TR201000686A1 - Bakteriyel enfeksiyonların tedavisinde suda çözünebilir sefdinir ve klavulanik asit formülasyonları.@ - Google Patents
Bakteriyel enfeksiyonların tedavisinde suda çözünebilir sefdinir ve klavulanik asit formülasyonları.@Info
- Publication number
- TR201000686A1 TR201000686A1 TR2010/00686A TR201000686A TR201000686A1 TR 201000686 A1 TR201000686 A1 TR 201000686A1 TR 2010/00686 A TR2010/00686 A TR 2010/00686A TR 201000686 A TR201000686 A TR 201000686A TR 201000686 A1 TR201000686 A1 TR 201000686A1
- Authority
- TR
- Turkey
- Prior art keywords
- cefdinir
- soluble
- treatment
- clavulanic acid
- water
- Prior art date
Links
- HZZVJAQRINQKSD-UHFFFAOYSA-N Clavulanic acid Natural products OC(=O)C1C(=CCO)OC2CC(=O)N21 HZZVJAQRINQKSD-UHFFFAOYSA-N 0.000 title abstract 2
- RTXOFQZKPXMALH-GHXIOONMSA-N cefdinir Chemical compound S1C(N)=NC(C(=N\O)\C(=O)N[C@@H]2C(N3C(=C(C=C)CS[C@@H]32)C(O)=O)=O)=C1 RTXOFQZKPXMALH-GHXIOONMSA-N 0.000 title abstract 2
- 229960003719 cefdinir Drugs 0.000 title abstract 2
- HZZVJAQRINQKSD-PBFISZAISA-N clavulanic acid Chemical compound OC(=O)[C@H]1C(=C/CO)/O[C@@H]2CC(=O)N21 HZZVJAQRINQKSD-PBFISZAISA-N 0.000 title abstract 2
- 229960003324 clavulanic acid Drugs 0.000 title abstract 2
- 208000035143 Bacterial infection Diseases 0.000 title 1
- 208000022362 bacterial infectious disease Diseases 0.000 title 1
- 238000009472 formulation Methods 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- 150000003839 salts Chemical class 0.000 abstract 4
- HBAQYPYDRFILMT-UHFFFAOYSA-N 8-[3-(1-cyclopropylpyrazol-4-yl)-1H-pyrazolo[4,3-d]pyrimidin-5-yl]-3-methyl-3,8-diazabicyclo[3.2.1]octan-2-one Chemical class C1(CC1)N1N=CC(=C1)C1=NNC2=C1N=C(N=C2)N1C2C(N(CC1CC2)C)=O HBAQYPYDRFILMT-UHFFFAOYSA-N 0.000 abstract 1
- 241000894006 Bacteria Species 0.000 abstract 1
- 208000035473 Communicable disease Diseases 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 150000004677 hydrates Chemical class 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2009—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/429—Thiazoles condensed with heterocyclic ring systems
- A61K31/43—Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
- A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
- A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
- A61K9/0007—Effervescent
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Inorganic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Bu buluş bakterilerin neden olduğu dirençli enfeksiyon hastalıklarının tedavisinde oral kullanıma uygun suda çözünebilir sefdinir ve klavulanik asit ve/ veya bunların farmasötik kabul edilebilir tuzları, hidratları, enantiomerleri, rasematları, organik tuzları, inorganik tuzları, esterleri, polimorflan, kristal formları ve amorf formlarını ve/veya bunlara ait kombinasyonları içeren farmasötik formulasyonlara ilişkindir.
Priority Applications (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| TR2010/00686A TR201000686A1 (tr) | 2010-01-29 | 2010-01-29 | Bakteriyel enfeksiyonların tedavisinde suda çözünebilir sefdinir ve klavulanik asit formülasyonları.@ |
| PCT/TR2011/000031 WO2011093827A1 (en) | 2010-01-29 | 2011-01-28 | Water dispersible cefdinir and clavulanic acid formulations for treatment of bacterial infections |
| PCT/TR2011/000025 WO2011093821A1 (en) | 2010-01-29 | 2011-01-28 | Effervescent formulations comprising cefdinir and clavulanic acid |
| EP11706649A EP2528584A1 (en) | 2010-01-29 | 2011-01-28 | Water dispersible cefdinir and clavulanic acid formulations for treatment of bacterial infections |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| TR2010/00686A TR201000686A1 (tr) | 2010-01-29 | 2010-01-29 | Bakteriyel enfeksiyonların tedavisinde suda çözünebilir sefdinir ve klavulanik asit formülasyonları.@ |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TR201000686A1 true TR201000686A1 (tr) | 2011-08-22 |
Family
ID=43829127
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TR2010/00686A TR201000686A1 (tr) | 2010-01-29 | 2010-01-29 | Bakteriyel enfeksiyonların tedavisinde suda çözünebilir sefdinir ve klavulanik asit formülasyonları.@ |
Country Status (3)
| Country | Link |
|---|---|
| EP (1) | EP2528584A1 (tr) |
| TR (1) | TR201000686A1 (tr) |
| WO (2) | WO2011093827A1 (tr) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2013095313A1 (en) * | 2011-12-19 | 2013-06-27 | Mahmut Bilgic | Pharmaceutical formulations comprising cefdinir |
| EP3694493A1 (en) * | 2017-10-13 | 2020-08-19 | Alfred E. Tiefenbacher (GmbH & Co. KG) | Tablet containing valsartan and sacubitril |
| CN111000805B (zh) * | 2020-01-03 | 2021-10-19 | 深圳市贝美药业有限公司 | 舒他西林颗粒制剂及其制备方法 |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1508977A (en) | 1974-04-20 | 1978-04-26 | Beecham Group Ltd | Beta-lactam antibiotic from streptomyces clavuligerus |
| ZA836918B (en) | 1982-09-30 | 1984-05-30 | Fujisawa Pharmaceutical Co | 7-substituted-3-vinyl-3-cephem compounds and processes for the production of the same |
| DK162718C (da) | 1982-09-30 | 1992-05-11 | Fujisawa Pharmaceutical Co | Analogifremgangsmaade til fremstilling af 7-substitueret-3-vinyl-3-cephemforbindelser |
| ZA885709B (en) | 1987-08-19 | 1989-04-26 | Fujisawa Pharmaceutical Co | Novel crystalline 7-(2-(2-aminothiazol-4-yl)-2-hydroxyiminoacetamido)-3-vinyl-3-cephem-4-carboxylic acid(syn isomer) |
| GB9408117D0 (en) | 1994-04-23 | 1994-06-15 | Smithkline Beecham Corp | Pharmaceutical formulations |
| ATE208618T1 (de) | 1995-09-07 | 2001-11-15 | Smithkline Beecham Corp | Verwendung einer amoxicillin und clavulanat enthaltenden paediatrischen pharmazeutischen formulierung |
| NZ330864A (en) * | 1996-02-29 | 2001-07-27 | Fujisawa Pharmaceutical Co | Beta-lactam antibiotic-containing tablet including a disintegrant and a binder |
| GB9815532D0 (en) * | 1998-07-17 | 1998-09-16 | Lek Pharmaceutical & Cvhemical | Pharmaceutical suspension formulation |
| AU2869100A (en) * | 1999-02-26 | 2000-09-14 | Biovail International Ltd. | Storage stable amoxycillin and clavulanate suspension composition |
| ES2202004T3 (es) | 1999-04-13 | 2004-04-01 | Beecham Pharmaceuticals (Pte) Limited | Novedoso procedimiento de tratamiento usando un fuerte regimen de dosificacion de amoxicilina y clavulanato potasico. |
| WO2004104010A1 (en) * | 2003-05-20 | 2004-12-02 | Ranbaxy Laboratories Limited | Crystalline form of cefdinir |
| US20060069079A1 (en) | 2004-09-27 | 2006-03-30 | Sever Nancy E | Stable amorphous cefdinir |
| GB0416379D0 (en) | 2004-07-22 | 2004-08-25 | Sandoz Ag | Organic compounds |
| CN1706389A (zh) * | 2005-05-26 | 2005-12-14 | 济南平志医药科技有限公司 | 头孢地尼泡腾制剂及其制备方法 |
| EP1943256A2 (en) | 2005-10-31 | 2008-07-16 | Teva Pharmaceutical Industries Ltd. | Crystalline forms of cefdinir potassium salt |
| US20070128268A1 (en) * | 2005-12-07 | 2007-06-07 | Herwig Jennewein | Pharmaceutical compositions comprising an antibiotic |
| US20090275552A1 (en) * | 2006-04-28 | 2009-11-05 | Mahesh Vithalbhai Patel | Therapy for Treating Resistant Bacterial Infections |
| US20080103124A1 (en) * | 2006-10-25 | 2008-05-01 | Astellas Pharma Inc. | Cefdinir-containing pharmaceutical composition |
| TR200909787A2 (tr) * | 2009-12-25 | 2011-07-21 | Bi̇lgi̇ç Mahmut | Üçüncü kuşak bir sefalosporin ve klavulanik asit içeren farmasötik formülasyonlar. |
-
2010
- 2010-01-29 TR TR2010/00686A patent/TR201000686A1/tr unknown
-
2011
- 2011-01-28 EP EP11706649A patent/EP2528584A1/en not_active Withdrawn
- 2011-01-28 WO PCT/TR2011/000031 patent/WO2011093827A1/en not_active Ceased
- 2011-01-28 WO PCT/TR2011/000025 patent/WO2011093821A1/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| WO2011093827A1 (en) | 2011-08-04 |
| WO2011093821A1 (en) | 2011-08-04 |
| EP2528584A1 (en) | 2012-12-05 |
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