[go: up one dir, main page]

TR201000625T1 - Kristal esitalopram bazı ve esatilopram baz içeren ağızda dağılan tabletler. - Google Patents

Kristal esitalopram bazı ve esatilopram baz içeren ağızda dağılan tabletler.

Info

Publication number
TR201000625T1
TR201000625T1 TR2010/00625T TR201000625T TR201000625T1 TR 201000625 T1 TR201000625 T1 TR 201000625T1 TR 2010/00625 T TR2010/00625 T TR 2010/00625T TR 201000625 T TR201000625 T TR 201000625T TR 201000625 T1 TR201000625 T1 TR 201000625T1
Authority
TR
Turkey
Prior art keywords
base
salts
esatilopram
tablets containing
disintegrating tablets
Prior art date
Application number
TR2010/00625T
Other languages
English (en)
Inventor
Petersen Hans
Nielsen Ole
Lijegren Ken
Dancer Robert
Eliasen Helle
Harold Rock Michael
Original Assignee
H. Lundbeck A/S
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=37546630&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=TR201000625(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by H. Lundbeck A/S filed Critical H. Lundbeck A/S
Publication of TR201000625T1 publication Critical patent/TR201000625T1/tr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/216—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acids having aromatic rings, e.g. benactizyne, clofibrate
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/87—Benzo [c] furans; Hydrogenated benzo [c] furans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A61K31/343—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B63/00—Purification; Separation; Stabilisation; Use of additives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Emergency Medicine (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Furan Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Mevcut buluş, iyi bilinen antidepresan ilaç esitalopramin kristal bazı, S-l-[3-(dimetilam no)propil]-l-(4-fiorofenil)-l,3-dihidro-5- izobenzofurankarbonitril, sözü edilen bazın formülasyonları, oksalat gibi, esitalopramın saflaştırılmış tuzlarının hazırlanması için, bir bazın kullanıldığı bir proses, sözü edilen proses yoluyla elde edilen tuzlar ve bu tip tuzları içeren formülasyonlar ve saflaştırılmış esitalopram serbest bazının veya oksalat gibi, esilatopramın tuzlarının hazırlanması için, hidrobromürün kullanıldığı bir proses, sözü edilen proses yoluyla elde edilen tuzlar ve bu tip tuzları içeren formülasyonlar ile ilgilidir.
TR2010/00625T 2005-06-22 2006-06-22 Kristal esitalopram bazı ve esatilopram baz içeren ağızda dağılan tabletler. TR201000625T1 (tr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DKPA200500912 2005-06-22

Publications (1)

Publication Number Publication Date
TR201000625T1 true TR201000625T1 (tr) 2010-03-22

Family

ID=37546630

Family Applications (2)

Application Number Title Priority Date Filing Date
TR2010/00625T TR201000625T1 (tr) 2005-06-22 2006-06-22 Kristal esitalopram bazı ve esatilopram baz içeren ağızda dağılan tabletler.
TR2007/08792T TR200708792T1 (tr) 2005-06-22 2006-06-22 Kristal esitalopram bazı ve esitalopram içeren ağızda dağılan tabletler

Family Applications After (1)

Application Number Title Priority Date Filing Date
TR2007/08792T TR200708792T1 (tr) 2005-06-22 2006-06-22 Kristal esitalopram bazı ve esitalopram içeren ağızda dağılan tabletler

Country Status (39)

Country Link
EP (3) EP2385044A1 (tr)
JP (5) JP4906852B2 (tr)
KR (5) KR20080018191A (tr)
CN (2) CN101189220A (tr)
AR (2) AR055062A1 (tr)
AT (3) ATE497500T1 (tr)
AU (2) AU2006261452B2 (tr)
BG (1) BG66086B1 (tr)
BR (1) BRPI0612295A2 (tr)
CA (2) CA2612827C (tr)
CY (1) CY1112392T1 (tr)
CZ (3) CZ301286B6 (tr)
DE (2) DE602006019961D1 (tr)
DK (3) DK1896439T4 (tr)
EA (2) EA019239B1 (tr)
EE (1) EE00773U1 (tr)
ES (2) ES2319073B1 (tr)
FI (2) FI20077133A7 (tr)
GB (2) GB2442160B (tr)
HR (1) HRP20110093T4 (tr)
HU (1) HUP0800135A3 (tr)
IL (1) IL187454A0 (tr)
IS (1) IS8705A (tr)
LT (1) LT5550B (tr)
LV (1) LV13677B (tr)
MX (1) MX2007015328A (tr)
MY (2) MY143239A (tr)
NO (2) NO20080359L (tr)
PL (2) PL384185A1 (tr)
PT (1) PT1896439E (tr)
RS (1) RS51575B2 (tr)
SG (1) SG169358A1 (tr)
SI (1) SI1896439T2 (tr)
SK (1) SK500402007A3 (tr)
TR (2) TR201000625T1 (tr)
TW (2) TWI347942B (tr)
UA (1) UA86536C2 (tr)
WO (1) WO2006136169A2 (tr)
ZA (2) ZA200711066B (tr)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0123400D0 (en) 2001-09-28 2001-11-21 Novartis Ag Organic compounds
WO2008059514A2 (en) * 2006-07-31 2008-05-22 Cadila Healthcare Limited Process for preparing escitalopram
WO2008104880A2 (en) * 2007-03-01 2008-09-04 Aurobindo Pharma Limited Stable solid dosage forms of an antidepressant
RS54715B1 (sr) 2010-07-23 2016-08-31 H. Lundbeck A/S Postupak za prečišćavanje farmaceutski prihvatljivih soli escitaloprama
CN103360353A (zh) * 2013-08-07 2013-10-23 中国药科大学 草酸艾司西酞普兰杂质的制备方法
JP2018016569A (ja) * 2016-07-26 2018-02-01 株式会社トクヤマ （１ｓ）−１−［３−（ジメチルアミノ）プロピル］−１−（４−フルオロフェニル）−１，３−ジヒドロイソベンゾフラン−５−カルボニトリル蓚酸塩の製造方法
WO2018190294A1 (ja) * 2017-04-10 2018-10-18 東和薬品株式会社 エスシタロプラム医薬組成物
CN110711198B (zh) * 2018-07-12 2022-03-15 山东大学 D-甘露糖在制备抗抑郁药物中的应用
KR102331187B1 (ko) 2019-04-09 2021-11-26 주식회사 라이트팜텍 에스시탈로프람을 함유하는 안정성이 우수한 경구용 액제 조성물 및 그의 제조방법
WO2022153262A1 (en) * 2021-01-18 2022-07-21 Anton Frenkel Pharmaceutical dosage form

Family Cites Families (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1526331A (en) 1976-01-14 1978-09-27 Kefalas As Phthalanes
GB8814057D0 (en) 1988-06-14 1988-07-20 Lundbeck & Co As H New enantiomers & their isolation
JPH05222041A (ja) * 1992-02-13 1993-08-31 Mitsubishi Gas Chem Co Inc アデニン誘導体の精製法
KR100258642B1 (ko) * 1994-01-27 2000-08-01 프랭크 왁스만 신속하게 용해되는 경구 제형
US5607697A (en) * 1995-06-07 1997-03-04 Cima Labs, Incorporated Taste masking microparticles for oral dosage forms
AU4655597A (en) 1997-06-30 1999-01-19 Beloit Technologies, Inc. Method and apparatus for the high speed application of coating to a traveling paper web
EA001728B1 (ru) 1997-07-08 2001-08-27 Х.Лундбекк А/С Способ получения циталопрама
CZ292911B6 (cs) 1997-11-11 2004-01-14 H. Lundbeck A/S Způsob výroby citalopramu
FR2785538B1 (fr) * 1998-11-06 2004-04-09 Prographarm Laboratoires Comprime a delitement rapide perfectionne
US20020071864A1 (en) * 1999-03-25 2002-06-13 Yuhan Corporation Rapidly disintegrable tablet for oral administration
ITMI991579A1 (it) 1999-06-25 2001-01-15 Lundbeck & Co As H Metodo per la preparazione di citalopram
ITMI991581A1 (it) 1999-06-25 2001-01-15 Lundbeck & Co As H Metodo per la preparazione di citalopram
JP2001226372A (ja) * 1999-12-06 2001-08-21 Sumika Fine Chemicals Co Ltd ロサルタンの結晶性または結晶化された酸付加塩およびロサルタンの精製方法
GB2357762B (en) * 2000-03-13 2002-01-30 Lundbeck & Co As H Crystalline base of citalopram
EP1329217A4 (en) * 2000-10-06 2007-04-04 Takeda Pharmaceutical Solid preparations
CN1469737A (zh) * 2000-10-16 2004-01-21 ��һ��������ҩ��ʽ���� 口腔内快速崩解的药用组合物及其制备方法
US7799342B2 (en) 2000-12-06 2010-09-21 Wyeth Llc Fast dissolving tablet
IL147226A (en) * 2000-12-22 2006-04-10 Lundbeck & Co As H Process for the preparation of pure citalopram
PL353369A1 (en) * 2000-12-28 2003-11-17 H.Lundbeck A/S Process for the preparation of pure citalopram
MEP5908A (xx) * 2001-05-01 2010-02-10 Lundbeck & Co As H Upotreba enantiomerno čistog escitaloprama
US6872405B2 (en) * 2001-05-10 2005-03-29 Yamanouchi Pharmaceutical Co., Ltd. Quick-disintegrating tablet in buccal cavity and manufacturing method thereof
GB0113842D0 (en) * 2001-06-07 2001-08-01 Boots Co Plc Therapeutic agents
AR034612A1 (es) * 2001-06-25 2004-03-03 Lundbeck & Co As H Proceso para la preparacion del citalopram racemico y/o del s- o r-citalopram mediante la separacion de una mezcla de r- y s-citalopram
AR034759A1 (es) 2001-07-13 2004-03-17 Lundbeck & Co As H Metodo para la preparacion de escitalopram
DK1522539T3 (da) * 2001-07-31 2007-05-07 Lundbeck & Co As H Krystallinsk komposition indeholdende excitalopram
IS7239A (is) 2001-12-14 2004-04-29 H. Lundbeck A/S Aðferð til framleiðslu á essítalóprami
US7148364B2 (en) * 2002-01-07 2006-12-12 Sun Pharmaceutical Industries Process for the preparation of 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-5-isobenzofuran carbonitrile
FR2834889B1 (fr) * 2002-01-18 2004-04-02 Roquette Freres Forme pharmaceutique solide orodispersible
GB0204607D0 (en) * 2002-02-27 2002-04-10 Matrix Lab Ltd Process
EP2228060A1 (en) * 2002-05-03 2010-09-15 Skyepharma Canada Inc. Oral dosage forms comprising fenofibrate
BR0317623A (pt) 2002-12-23 2005-11-29 Lundbeck & Co As H Escitalopram, composição farmacêutica, e, uso de hidrobrometo de escitalopram
CN1510024A (zh) * 2002-12-24 2004-07-07 北京德众万全药物技术开发有限公司 可用于制备西酞普兰(s)-对映异构体的新的化合物及其制备方法
DE10305984A1 (de) * 2003-02-13 2004-09-02 Helm Ag Salze organischer Säuren mit Clopidogrel und deren Verwendung zur Herstellung phamazeutischer Formulierungen
US7749533B2 (en) * 2003-05-07 2010-07-06 Akina, Inc. Highly plastic granules for making fast melting tablets
US8647668B2 (en) * 2003-10-15 2014-02-11 Fuji Chemical Industry Co., Ltd. Tablet quickly disintegrating in oral cavity
AU2003282383A1 (en) * 2003-11-20 2005-06-08 Natco Pharma Limited A process for the preparation of high purity escitalopram
HU227491B1 (en) * 2003-11-25 2011-07-28 Egis Gyogyszergyar Nyilvanosan Muekoedoe Reszvenytarsasag Tablet containing citalopram hydrogen bromide
CA2558198A1 (en) * 2004-03-05 2005-09-15 H. Lundbeck A/S Crystalline composition containing escitalopram oxalate
EP1877394A1 (en) * 2005-04-04 2008-01-16 Jubilant Organosys Limited Process for the preparation of escitalopram or its acid addition salts

Also Published As

Publication number Publication date
JP2009179635A (ja) 2009-08-13
CA2612827C (en) 2010-11-30
DK200800075A (da) 2008-03-15
KR20080018191A (ko) 2008-02-27
EA019239B1 (ru) 2014-02-28
AT11883U1 (de) 2011-06-15
DK200900284A (da) 2009-02-27
FI20077133L (fi) 2007-12-20
LT2008005A (en) 2008-10-27
EP1896439A2 (en) 2008-03-12
HUP0800135A2 (en) 2008-06-30
SI1896439T1 (sl) 2011-03-31
PL1896439T3 (pl) 2011-04-29
EA200800102A1 (ru) 2008-04-28
JP5731957B2 (ja) 2015-06-10
ZA200711066B (en) 2009-07-29
GB2448834B (en) 2010-01-20
CN101189220A (zh) 2008-05-28
MY143239A (en) 2011-04-15
NO20080359L (no) 2008-01-18
TW200740785A (en) 2007-11-01
HRP20110093T1 (hr) 2011-03-31
HUP0800135A3 (en) 2009-01-28
JP4906852B2 (ja) 2012-03-28
GB2448834A (en) 2008-10-29
WO2006136169A3 (en) 2007-10-18
GB0724557D0 (en) 2008-01-23
ZA200901698B (en) 2010-04-28
EA201001108A1 (ru) 2011-02-28
AT10983U1 (de) 2010-02-15
JP4415056B2 (ja) 2010-02-17
ATE497500T1 (de) 2011-02-15
GB0811164D0 (en) 2008-07-23
AU2010200844A1 (en) 2010-04-01
RS51575B (sr) 2011-08-31
KR20120064140A (ko) 2012-06-18
KR20110084341A (ko) 2011-07-21
SK500402007A3 (sk) 2008-05-06
WO2006136169A2 (en) 2006-12-28
EP2325177A1 (en) 2011-05-25
CZ2007898A3 (cs) 2008-01-23
CA2612827A1 (en) 2006-12-28
AU2006261452B2 (en) 2010-02-04
BG66086B1 (bg) 2011-03-31
IS8705A (is) 2008-01-14
DE112006001619T5 (de) 2008-06-12
CZ299906B6 (cs) 2008-12-29
GB2442160B (en) 2010-01-20
MY143252A (en) 2011-04-15
FI20077133A7 (fi) 2007-12-20
JP2009046506A (ja) 2009-03-05
ES2319073A1 (es) 2009-05-01
IL187454A0 (en) 2008-02-09
DK1896439T4 (en) 2015-01-12
JP2008546724A (ja) 2008-12-25
CY1112392T1 (el) 2015-12-09
CZ301286B6 (cs) 2009-12-30
KR20110033310A (ko) 2011-03-30
LT5550B (lt) 2009-03-25
CA2646780A1 (en) 2006-12-28
PT1896439E (pt) 2011-02-15
FI20080548L (fi) 2008-10-07
GB2442160A (en) 2008-03-26
TWI347942B (en) 2011-09-01
BRPI0612295A2 (pt) 2011-01-04
MX2007015328A (es) 2008-02-15
EP1896439B1 (en) 2011-02-02
AR079750A2 (es) 2012-02-15
BG110024A (bg) 2008-05-30
RS51575B2 (sr) 2018-02-28
SG169358A1 (en) 2011-03-30
JP2009179634A (ja) 2009-08-13
ES2319073B1 (es) 2010-02-26
HRP20110093T4 (hr) 2015-02-27
EE00773U1 (et) 2008-10-15
AU2006261452A1 (en) 2006-12-28
DK1896439T3 (da) 2011-02-28
JP2012072168A (ja) 2012-04-12
KR101340815B1 (ko) 2013-12-11
TWI358407B (en) 2012-02-21
CZ300686B6 (cs) 2009-07-15
PL1896439T5 (pl) 2016-01-29
EP2385044A1 (en) 2011-11-09
LV13677B (en) 2008-05-20
PL384185A1 (pl) 2008-06-23
KR20100133023A (ko) 2010-12-20
TR200708792T1 (tr) 2008-05-21
ES2356838T5 (es) 2015-01-26
NO20101777L (no) 2008-01-18
TW201130808A (en) 2011-09-16
FI20080548A7 (fi) 2008-10-07
SI1896439T2 (sl) 2014-12-31
DE602006019961D1 (de) 2011-03-17
UA86536C2 (ru) 2009-04-27
EP1896439B2 (en) 2014-10-15
AR055062A1 (es) 2007-08-01
CN101928269A (zh) 2010-12-29
ES2356838T3 (es) 2011-04-13

Similar Documents

Publication Publication Date Title
TR200202185T2 (tr) Sitalopramın kristalin bazı.
CY1112392T1 (el) Κρυσταλλικη βαση εσκιταλοπραμης και δισκια διασπειρομενα στο στομα που αποτελουνται απο βαση εσκιταλοπραμης
ES2195554T3 (es) Metodo para la preparacion de citalopram.
ATE299494T1 (de) Carbamat-derivate als muscarin-rezeptor antonisten
UA95237C2 (uk) Імуногенна композиція
AR060732A1 (es) Usos del escitalopram
EA200870489A1 (ru) Пиперидинилзамещённые пирролидиноны в качестве ингибиторов 11-бета-гидроксистероид дегидрогеназы 1
ATE555105T1 (de) Heterocyclische fxr-bindende verbindungen
CY1112398T1 (el) Πυρρολιδινονες υποκατασταθεισες απο κυκλοεξυλιο ως αναστολεις της 11-β-υδροξυστεροειδικης αφυδρογονασης 1
BR122013025375B8 (pt) compostos orgânicos, seus métodos de preparo e uso, bem como composições farmacêuticas
CY1111859T1 (el) Παραγωγα φαινυλ-{3-(3-(1η-πυρρολ-2-υλ)-[1,2,4]οξαδιαζολ-5-υλ]πιπεριδιν-1-υλ}-μεθανονης και σχετικες ενωσεις ως θετικοι αλλοστερικοι ρυθμιστες μεταβοτροπικων υποδοχεων γλουταμικου
CL2008000212A1 (es) Compuestos derivados de fenotiazina; composicion farmaceutica que comprende a dichos compuestos; y su uso para tratar diabetes, reducir los niveles de glucemia, adiccion a nicotina, adiccion al alcohol, trastornos del sistema nervioso central, entre
PE20080362A1 (es) Derivados de ciclohexilpirazol-lactama como inhibidores de 11-beta-hidroxiesteroide deshidrogenasa 1
NO20064579L (no) Bifenylforbindelser anvendelige som muskariniske receptorantagonister
CY1108880T1 (el) Παραγωγα καρβοξαμιδιου ως ανταγωνιστες μουσκαρινικου υποδοχεα
CY1106857T1 (el) Βενζαμιδια 4-(αμινομεθυλ)-πιπεριδινης ως 5ht4-ανταγωνιστες
IL189191A0 (en) Thiazolyl piperidine derivatives useful as h3 receptor modulators
EA201190319A1 (ru) Твердая фармацевтическая композиция, содержащая ривароксабан
EA201000087A1 (ru) Кристаллическая форма [3-(4,5-дигидро-3-изоксазолил)-2-метил-4-(метилсульфонил)фенил]-(5-гидрокси-1-метил-1h-пиразол-4-ил)метанона
EA200601194A1 (ru) Новые производные бензофурана, используемые для профилактики или лечения нарушений, связанных с 5-ht-рецептором
CY1108366T1 (el) Βενζοσουλφονικο αλας της 7-(2-(4-(3-τριφθορομεθυλ-φαινυλ-1,2,3,6-τετραϋδρο-πυριδ-1-υλ)αιθυλ)ισοκινολινης, η παρασκευη του και η χρηση του στη φαρμακευτικη αγωγη
EA200601895A1 (ru) 3-(4-гетероарилциклогексиламино)циклопентанкарбоксамиды в качестве модуляторов хемокиновых рецепторов
BRPI0909737A2 (pt) compostos de pirrolidinila, composição farmacêutica compreendendo os mesmos e usos dos mesmos
TR200200310T2 (tr) Interlökin-5 inhibe eden 6-azaurasil türevleri.
EA201071309A1 (ru) Твердая фармацевтическая композиция