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TR200504890T1 - Benipidin hidroklorür içeren farmasötik bileşim - Google Patents

Benipidin hidroklorür içeren farmasötik bileşim

Info

Publication number
TR200504890T1
TR200504890T1 TR2005/04890T TR200504890T TR200504890T1 TR 200504890 T1 TR200504890 T1 TR 200504890T1 TR 2005/04890 T TR2005/04890 T TR 2005/04890T TR 200504890 T TR200504890 T TR 200504890T TR 200504890 T1 TR200504890 T1 TR 200504890T1
Authority
TR
Turkey
Prior art keywords
hydrochloride
pharmaceutical composition
benipidine
benidipine
composition containing
Prior art date
Application number
TR2005/04890T
Other languages
English (en)
Inventor
Goto Tomohiko
Hayakawa Eiji
Takeshige Kazuhiko
Original Assignee
Kyowa Hakko Kogyo Co., Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kyowa Hakko Kogyo Co., Ltd. filed Critical Kyowa Hakko Kogyo Co., Ltd.
Publication of TR200504890T1 publication Critical patent/TR200504890T1/tr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/4545—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Mevcut buluş, benidipin hidroklorür içeren bir farmasötik bileşim ve benzerlerini sağlamaktadır, özelliği, ana bileşen olan benidipin hidroklorürün emilimini hızlandıran hızlı çözünme özelliğine sahip olan benidipin hidroklorür içeren bir farmasötikbileşim ve benzerlerini sağlamak için, bileşimin hacim-ortalama parçacık boyutu 1.0 ila 50.0 um olan kristalimsi benidipin hidroklorür içermesi veya kristalimsi benidipin hidroklorür ve suda çözünebilen veya su çekici yardımcı madde içeren, hacim-ortalama parçacık boyutu 1.0 ila 50.0 um olan toz parçacıkları içermesidir.
TR2005/04890T 2003-06-17 2005-12-08 Benipidin hidroklorür içeren farmasötik bileşim TR200504890T1 (tr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2003171503 2003-06-17

Publications (1)

Publication Number Publication Date
TR200504890T1 true TR200504890T1 (tr) 2006-08-21

Family

ID=33549456

Family Applications (1)

Application Number Title Priority Date Filing Date
TR2005/04890T TR200504890T1 (tr) 2003-06-17 2005-12-08 Benipidin hidroklorür içeren farmasötik bileşim

Country Status (5)

Country Link
JP (1) JP3786287B2 (tr)
KR (1) KR101060885B1 (tr)
CN (2) CN102166212A (tr)
TR (1) TR200504890T1 (tr)
WO (1) WO2004110448A1 (tr)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070042049A1 (en) * 2005-06-03 2007-02-22 Elan Pharma International, Limited Nanoparticulate benidipine compositions
WO2008117707A1 (ja) * 2007-03-23 2008-10-02 Daiichi Sankyo Company, Limited オルメサルタンメドキソミルの粉砕結晶
CN104324015B (zh) 2007-03-29 2018-08-28 第一三共株式会社 药物组合物
CN102791271B (zh) 2010-03-19 2014-05-14 第一三共株式会社 抗凝剂的溶出改善方法
JP5590228B2 (ja) * 2011-04-18 2014-09-17 ヘフェイ ベイニ メディカル テクノロジー カンパニー リミテッド ベニジピン塩酸塩のナノ粒子の調製方法
US20140031557A1 (en) 2011-04-18 2014-01-30 Hefeibeinie Medical Technology Company, Ltd. Method for purification of calcium channel blockers of dihydorpyridine type and preparation of nanoparticles thereof
US9402907B2 (en) 2011-08-10 2016-08-02 Daiichi Sankyo Company, Limited Pharmaceutical composition containing diamine derivative
CN102362865B (zh) * 2011-10-28 2013-06-26 山东司邦得制药有限公司 一种含有盐酸贝尼地平和缬沙坦的复方制剂及其应用
CN115784973A (zh) * 2021-09-09 2023-03-14 四川科瑞德制药股份有限公司 一种盐酸贝尼地平及其制备方法、制剂和用途
TR2024007785A1 (tr) 2024-06-14 2025-12-22 Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi Beni̇di̇pi̇n i̇çeren tablet bi̇leşi̇mi̇
CN118717697B (zh) * 2024-09-04 2025-03-25 杭州沐源生物医药科技有限公司 一种盐酸贝尼地平片组合物及其制备方法和应用
CN119732916B (zh) * 2024-12-25 2025-10-14 北京阳光诺和药物研究股份有限公司 一种片剂钙通道阻滞剂及其制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS55129221A (en) * 1979-03-29 1980-10-06 Kaken Pharmaceut Co Ltd Preparation of oral preparation containing hardly soluble medicine
JPS59137461A (ja) * 1983-01-27 1984-08-07 Kyowa Hakko Kogyo Co Ltd １，４−ジヒドロピリジン誘導体
JPH06128147A (ja) * 1992-10-20 1994-05-10 Masayasu Sugihara 水難溶性薬品の溶解性改善方法およびそれにより得られた薬品組成物
JPH07126154A (ja) * 1993-10-29 1995-05-16 Terumo Corp 難水溶性医薬品含有医薬製剤
JP2003104888A (ja) * 2001-09-28 2003-04-09 Taiyo Yakuhin Kogyo Kk ジヒドロピリジン誘導体の錠剤

Also Published As

Publication number Publication date
KR20060020681A (ko) 2006-03-06
JPWO2004110448A1 (ja) 2006-07-20
WO2004110448A1 (ja) 2004-12-23
CN102166212A (zh) 2011-08-31
CN1794993A (zh) 2006-06-28
JP3786287B2 (ja) 2006-06-14
KR101060885B1 (ko) 2011-08-31

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