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TR200201679T2 - New heteroaryl derivatives, their preparation and uses. - Google Patents

New heteroaryl derivatives, their preparation and uses.

Info

Publication number
TR200201679T2
TR200201679T2 TR2002/01679T TR200201679T TR200201679T2 TR 200201679 T2 TR200201679 T2 TR 200201679T2 TR 2002/01679 T TR2002/01679 T TR 2002/01679T TR 200201679 T TR200201679 T TR 200201679T TR 200201679 T2 TR200201679 T2 TR 200201679T2
Authority
TR
Turkey
Prior art keywords
discomfort
preparation
heteroaryl derivatives
new heteroaryl
new
Prior art date
Application number
TR2002/01679T
Other languages
Turkish (tr)
Inventor
Ruhland Thomas
Krog-Jensen Christian
Mikkelsen Ivan
Rottlander Mario
Mikkelsen Gitte
Knud Moltzen Ejner
Andersen Kim
Original Assignee
H. Lundbeck A/S
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by H. Lundbeck A/S filed Critical H. Lundbeck A/S
Publication of TR200201679T2 publication Critical patent/TR200201679T2/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/10—1,4-Dioxanes; Hydrogenated 1,4-dioxanes
    • C07D319/14—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems
    • C07D319/16—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D319/18—Ethylenedioxybenzenes, not substituted on the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)

Abstract

Formül I'e sahip olan bir heteroaril türevi, bunun tüm enantiomerleri yada herhangi bir karisimdir. Bulusun bilesikleri genel asiri heyecan rahatsizligi, panik rahatsizligi, obsesif kompulsif rahatsizlik, depresyon, sosyal fobi ve beslenme rahatsizliklari gibi duygusal kaynakli rahatsizliklarin ve pisikoz gibi nörolojik rahatsizliklarin tedavisi için yararli olarak degerlendirilmektedirler.A heteroaryl derivative of Formula I is all its enantiomers or any mixture thereof. Compounds of the invention are considered useful for the treatment of emotional disturbances such as generalized excitement, discomfort, panic discomfort, obsessive compulsive discomfort, depression, social phobia and nutritional discomfort, and neurological discomforts such as psychosis.

TR2002/01679T 1999-12-30 2000-12-29 New heteroaryl derivatives, their preparation and uses. TR200201679T2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DKPA199901884 1999-12-30

Publications (1)

Publication Number Publication Date
TR200201679T2 true TR200201679T2 (en) 2002-10-21

Family

ID=8108797

Family Applications (1)

Application Number Title Priority Date Filing Date
TR2002/01679T TR200201679T2 (en) 1999-12-30 2000-12-29 New heteroaryl derivatives, their preparation and uses.

Country Status (22)

Country Link
US (1) US20030050306A1 (en)
EP (1) EP1246820A1 (en)
JP (1) JP2003519229A (en)
KR (1) KR20020063286A (en)
CN (1) CN1414963A (en)
AR (1) AR027133A1 (en)
AU (1) AU2352001A (en)
BG (1) BG106846A (en)
BR (1) BR0016954A (en)
CA (1) CA2395984A1 (en)
CZ (1) CZ20022280A3 (en)
EA (1) EA200200733A1 (en)
HU (1) HUP0204084A3 (en)
IL (1) IL149993A0 (en)
IS (1) IS6403A (en)
NO (1) NO20023188L (en)
NZ (1) NZ519478A (en)
PL (1) PL355610A1 (en)
SK (1) SK9432002A3 (en)
TR (1) TR200201679T2 (en)
WO (1) WO2001049683A1 (en)
ZA (1) ZA200204464B (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5080716B2 (en) * 2001-07-20 2012-11-21 サイコジェニックス・インコーポレーテッド Treatment of attention deficit / hyperactivity disorder
TWI320783B (en) 2005-04-14 2010-02-21 Otsuka Pharma Co Ltd Heterocyclic compound
TWI329641B (en) * 2005-08-31 2010-09-01 Otsuka Pharma Co Ltd (benzo[b]thiophen-4-yl)piperazine compounds, pharmaceutical compositions comprising the same, uses of the same and processes for preparing the same
AU2007286807B2 (en) 2006-08-21 2013-03-21 Genentech, Inc. Aza-benzothiophenyl compounds and methods of use
JP4785881B2 (en) * 2007-02-27 2011-10-05 大塚製薬株式会社 Medicine

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK148392D0 (en) * 1992-12-09 1992-12-09 Lundbeck & Co As H Heterocyclic Compounds
IT1266582B1 (en) * 1993-07-30 1997-01-09 Recordati Chem Pharm (DI) AZACYLO-HEXANIC AND DIAZACYLO-HEPTANIC DERIVATIVES
AR022303A1 (en) * 1999-01-22 2002-09-04 Lundbeck & Co As H DERIVATIVES OF PIPERIDINE, TETRAHYDROPIRIDINE AND PIPERAZINE, ITS PREPARATION AND USE

Also Published As

Publication number Publication date
NO20023188D0 (en) 2002-07-01
NO20023188L (en) 2002-07-01
CA2395984A1 (en) 2001-07-12
WO2001049683A1 (en) 2001-07-12
BG106846A (en) 2003-02-28
CN1414963A (en) 2003-04-30
KR20020063286A (en) 2002-08-01
BR0016954A (en) 2003-04-29
HUP0204084A3 (en) 2005-02-28
JP2003519229A (en) 2003-06-17
HUP0204084A2 (en) 2003-03-28
EA200200733A1 (en) 2002-12-26
IS6403A (en) 2002-05-31
AU2352001A (en) 2001-07-16
NZ519478A (en) 2004-02-27
EP1246820A1 (en) 2002-10-09
ZA200204464B (en) 2003-09-04
AR027133A1 (en) 2003-03-12
IL149993A0 (en) 2002-12-01
SK9432002A3 (en) 2002-11-06
US20030050306A1 (en) 2003-03-13
PL355610A1 (en) 2004-05-04
CZ20022280A3 (en) 2002-10-16

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