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TR200201204T2 - ACAT inhibitörleriyle plak rüptürünün engellenmesi. - Google Patents

ACAT inhibitörleriyle plak rüptürünün engellenmesi.

Info

Publication number
TR200201204T2
TR200201204T2 TR2002/01204T TR200201204T TR200201204T2 TR 200201204 T2 TR200201204 T2 TR 200201204T2 TR 2002/01204 T TR2002/01204 T TR 2002/01204T TR 200201204 T TR200201204 T TR 200201204T TR 200201204 T2 TR200201204 T2 TR 200201204T2
Authority
TR
Turkey
Prior art keywords
prevention
plaque rupture
acat inhibitors
relates
rupture
Prior art date
Application number
TR2002/01204T
Other languages
English (en)
Inventor
Michael Andrew Bocan Thomas
Original Assignee
Warner Lambert Company
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner Lambert Company filed Critical Warner Lambert Company
Publication of TR200201204T2 publication Critical patent/TR200201204T2/tr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/18—Sulfonamides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/255—Esters, e.g. nitroglycerine, selenocyanates of sulfoxy acids or sulfur analogues thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/27—Esters, e.g. nitroglycerine, selenocyanates of carbamic or thiocarbamic acids, meprobamate, carbachol, neostigmine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Emergency Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Indole Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Bu bulus, ateroskleroz lezyonlarinda monosit-makrofaz birikmesini ve MMP ifadesini önlemek için bir ACAT inhibitörü verilmesiyle ilgilidir. Dahasi bu bulus, aterosklerotik plaklarin destabilizasyonu ve/veya da kopmasini inhibe etme ve stabil olmayan anjin tedavisi yöntemleri ile de ilgilidir.
TR2002/01204T 1999-11-05 2000-10-17 ACAT inhibitörleriyle plak rüptürünün engellenmesi. TR200201204T2 (tr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US16381499P 1999-11-05 1999-11-05

Publications (1)

Publication Number Publication Date
TR200201204T2 true TR200201204T2 (tr) 2002-08-21

Family

ID=22591694

Family Applications (1)

Application Number Title Priority Date Filing Date
TR2002/01204T TR200201204T2 (tr) 1999-11-05 2000-10-17 ACAT inhibitörleriyle plak rüptürünün engellenmesi.

Country Status (19)

Country Link
EP (1) EP1229907A1 (tr)
JP (1) JP2003513909A (tr)
KR (1) KR20020050257A (tr)
CN (1) CN1414848A (tr)
AR (1) AR026354A1 (tr)
AU (1) AU1210401A (tr)
CA (1) CA2382676A1 (tr)
CO (1) CO5270017A1 (tr)
GT (1) GT200000193A (tr)
HU (1) HUP0203160A3 (tr)
IL (1) IL149145A0 (tr)
PA (1) PA8506101A1 (tr)
PE (1) PE20011027A1 (tr)
PL (1) PL355148A1 (tr)
SV (1) SV2001000207A (tr)
TR (1) TR200201204T2 (tr)
UY (1) UY26427A1 (tr)
WO (1) WO2001034127A1 (tr)
ZA (1) ZA200201755B (tr)

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RU2358734C2 (ru) 2003-08-29 2009-06-20 Кова Ко., Лтд. Способ стабилизации бляшки с высоким содержанием липидов и способ профилактики ее разрушения
PT1755642E (pt) * 2004-04-15 2010-04-20 Athera Biotechnologies Ab Anexina v para prevenção de aterotrombose e da ruptura de placas
CN105360132A (zh) 2010-11-03 2016-03-02 陶氏益农公司 杀虫组合物和与其相关的方法
PH12014500930A1 (en) 2011-10-26 2014-06-09 Dow Agrosciences Llc Pesticidal compositions and processes related thereto
US8901153B2 (en) 2012-04-27 2014-12-02 Dow Agrosciences, Llc. Pesticidal compositions and processes related thereto
US9282739B2 (en) 2012-04-27 2016-03-15 Dow Agrosciences Llc Pesticidal compositions and processes related thereto
US9708288B2 (en) 2012-04-27 2017-07-18 Dow Agrosciences Llc Pesticidal compositions and processes related thereto
EP3057426A4 (en) 2013-10-17 2017-03-29 Dow AgroSciences LLC Processes for the preparation of pesticidal compounds
WO2015058021A1 (en) 2013-10-17 2015-04-23 Dow Agrosciences Llc Processes for the preparation of pesticidal compounds
JP2016535010A (ja) 2013-10-17 2016-11-10 ダウ アグロサイエンシィズ エルエルシー 有害生物防除性化合物の製造方法
MX2016004940A (es) 2013-10-17 2016-06-28 Dow Agrosciences Llc Proceso para la preparacion de compuestos plaguicidas.
CA2925595A1 (en) 2013-10-17 2015-04-23 Dow Agrosciences Llc Processes for the preparation of pesticidal compounds
CN105636445B (zh) 2013-10-17 2018-12-07 美国陶氏益农公司 制备杀虫化合物的方法
CA2925952A1 (en) 2013-10-17 2015-04-23 Dow Agrosciences Llc Processes for the preparation of pesticidal compounds
JP2016536307A (ja) 2013-10-22 2016-11-24 ダウ アグロサイエンシィズ エルエルシー 農薬組成物および関連する方法
JP2016534068A (ja) 2013-10-22 2016-11-04 ダウ アグロサイエンシィズ エルエルシー 相乗的有害生物防除組成物および関連する方法
JP2016535024A (ja) 2013-10-22 2016-11-10 ダウ アグロサイエンシィズ エルエルシー 相乗的有害生物防除組成物および関連する方法
KR20160074581A (ko) 2013-10-22 2016-06-28 다우 아그로사이언시즈 엘엘씨 상승작용적 살충 조성물 및 관련 방법
KR20160074640A (ko) 2013-10-22 2016-06-28 다우 아그로사이언시즈 엘엘씨 살충 조성물 및 관련 방법
JP2016538265A (ja) 2013-10-22 2016-12-08 ダウ アグロサイエンシィズ エルエルシー 相乗的有害生物防除組成物および関連する方法
EP3062619B1 (en) 2013-10-22 2019-07-24 Dow AgroSciences LLC Pesticidal compositions and related methods
TW201519786A (zh) 2013-10-22 2015-06-01 陶氏農業科學公司 殺蟲組成物及相關方法（一）
MX2016005310A (es) 2013-10-22 2016-08-08 Dow Agrosciences Llc Composiciones pesticidas sinergicas y metodos relacionados.
CA2926433A1 (en) 2013-10-22 2015-04-30 Dow Agrosciences Llc Pesticidal compositions and related methods
NZ720023A (en) 2013-10-22 2017-09-29 Dow Agrosciences Llc Synergistic pesticidal compositions and related methods
NZ719754A (en) 2013-10-22 2017-06-30 Dow Agrosciences Llc Synergistic pesticidal compositions and related methods
AU2014340412B2 (en) 2013-10-22 2017-04-20 Dow Agrosciences Llc Synergistic pesticidal compositions and related methods
NZ719541A (en) 2013-10-22 2017-11-24 Dow Agrosciences Llc Synergistic pesticidal compositions and related methods
EP3060050A4 (en) 2013-10-22 2017-04-05 Dow AgroSciences LLC Synergistic pesticidal compositions and related methods
WO2015061163A1 (en) 2013-10-22 2015-04-30 Dow Agrosciences Llc Pesticidal compositions and related methods
JP2016535025A (ja) 2013-10-22 2016-11-10 ダウ アグロサイエンシィズ エルエルシー 相乗的有害生物防除組成物および関連する方法
JP2017523168A (ja) 2014-07-31 2017-08-17 ダウ アグロサイエンシィズ エルエルシー ３−（３−クロロ−１ｈ−ピラゾール−１−イル）ピリジンの製造方法
CN106488909A (zh) 2014-07-31 2017-03-08 美国陶氏益农公司 制备3‑(3‑氯‑1h‑吡唑‑1‑基)吡啶的方法
KR20170039121A (ko) 2014-07-31 2017-04-10 다우 아그로사이언시즈 엘엘씨 3-(3-클로로-1h-피라졸-1-일)피리딘의 제조 방법
KR20170042714A (ko) 2014-08-19 2017-04-19 다우 아그로사이언시즈 엘엘씨 3-(3-클로로-1h-피라졸-1-일)피리딘의 제조 방법
JP2017528469A (ja) 2014-09-12 2017-09-28 ダウ アグロサイエンシィズ エルエルシー ３−（３−クロロ−１ｈ−ピラゾール−１−イル）ピリジンの調製方法
US10377781B2 (en) * 2014-10-21 2019-08-13 Council Of Scientific & Industrial Research Alkylidene phosphonate esters as p-glycoprotein inducers
US20190275012A9 (en) * 2016-07-29 2019-09-12 Lupin Limited Substituted thiazolo-pyridine compounds as malt1 inhibitors
KR102502031B1 (ko) 2016-11-16 2023-02-20 퍼듀 리서치 파운데이션 체중 및 대사 증후군을 조절하기 위한 조성물 및 방법
BR112019008372B1 (pt) 2016-12-29 2021-11-09 Dow Agrosciences Llc Processo para preparação de compostos pesticidas
WO2018125817A1 (en) 2016-12-29 2018-07-05 Dow Agrosciences Llc Processes for the preparation of pesticidal compounds
DK3700907T3 (da) 2017-10-27 2022-05-30 Bayer Ag Hidtil ukendte pyrazolo-pyrrolo-pyrimidindion-derivater som p2x3-inhibitorer
CA3121202A1 (en) 2018-11-30 2020-06-04 Nuvation Bio Inc. Pyrrole and pyrazole compounds and methods of use thereof

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0555351B1 (en) * 1990-10-30 1994-12-28 Warner-Lambert Company Oxysulfonyl carbamates
IL109431A (en) * 1993-05-14 2001-01-11 Warner Lambert Co Pharmaceutical compositions containing n-acyl sulfamic acid esters (or thioesters), n-acyl sulfonamides, and n-sulfonyl carbamic acid esters (or thioesters), for regulating plasma cholesterol concentration, and certain such novel compounds
IT1270976B (it) * 1993-08-06 1997-05-26 Pierrel Spa Composti inibitpri di acil enzima-a-colesterolo-o-acil transferasi ad attivita' terapeutica, loro uso e composizioni farmaceutiche che li contengono
EA002435B1 (ru) * 1995-08-04 2002-04-25 Варнер-Ламберт Компани Способ снижения уровня липопротеина (а) в сыворотке или в плазме крови млекопитающих
DE69636783T2 (de) * 1995-11-02 2007-10-18 Warner-Lambert Co. Llc Verfahren und pharmazeutische zusammensetzung zur regelung der lipidkonzentration
EA200100153A1 (ru) * 1998-07-21 2001-08-27 Варнер-Ламберт Компани Совместное назначение ингибиторов асат и ммр для лечения атеросклеротических поражений

Also Published As

Publication number Publication date
HUP0203160A3 (en) 2006-02-28
CN1414848A (zh) 2003-04-30
KR20020050257A (ko) 2002-06-26
AU1210401A (en) 2001-06-06
GT200000193A (es) 2002-04-27
CO5270017A1 (es) 2003-04-30
JP2003513909A (ja) 2003-04-15
HUP0203160A2 (hu) 2003-01-28
AR026354A1 (es) 2003-02-05
ZA200201755B (en) 2003-08-27
PA8506101A1 (es) 2002-10-28
WO2001034127A1 (en) 2001-05-17
SV2001000207A (es) 2001-10-16
CA2382676A1 (en) 2001-05-17
UY26427A1 (es) 2000-12-29
EP1229907A1 (en) 2002-08-14
IL149145A0 (en) 2002-11-10
PE20011027A1 (es) 2001-10-16
PL355148A1 (en) 2004-04-05

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