TR200201103T2 - İkame edilmiş benzimidazol formülasyonları - Google Patents
İkame edilmiş benzimidazol formülasyonlarıInfo
- Publication number
- TR200201103T2 TR200201103T2 TR2002/01103T TR200201103T TR200201103T2 TR 200201103 T2 TR200201103 T2 TR 200201103T2 TR 2002/01103 T TR2002/01103 T TR 2002/01103T TR 200201103 T TR200201103 T TR 200201103T TR 200201103 T2 TR200201103 T2 TR 200201103T2
- Authority
- TR
- Turkey
- Prior art keywords
- sodium
- potassium salt
- free
- polyethylene glycol
- glycol solution
- Prior art date
Links
- 238000009472 formulation Methods 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 title abstract 2
- 125000003785 benzimidazolyl group Chemical class N1=C(NC2=C1C=CC=C2)* 0.000 title 1
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 abstract 4
- KWYUFKZDYYNOTN-UHFFFAOYSA-M Potassium hydroxide Chemical compound [OH-].[K+] KWYUFKZDYYNOTN-UHFFFAOYSA-M 0.000 abstract 3
- XAEFZNCEHLXOMS-UHFFFAOYSA-M potassium benzoate Chemical compound [K+].[O-]C(=O)C1=CC=CC=C1 XAEFZNCEHLXOMS-UHFFFAOYSA-M 0.000 abstract 3
- 229910052708 sodium Inorganic materials 0.000 abstract 3
- 239000011734 sodium Substances 0.000 abstract 3
- 229940121819 ATPase inhibitor Drugs 0.000 abstract 2
- 239000002202 Polyethylene glycol Substances 0.000 abstract 2
- 239000000362 adenosine triphosphatase inhibitor Substances 0.000 abstract 2
- 239000012669 liquid formulation Substances 0.000 abstract 2
- 229920001223 polyethylene glycol Polymers 0.000 abstract 2
- HEMHJVSKTPXQMS-UHFFFAOYSA-M sodium hydroxide Inorganic materials [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 abstract 2
- 208000018522 Gastrointestinal disease Diseases 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Inorganic Chemistry (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
Mevcut bulus, su içermeyen ya da neredeyse hiç su içermeyen, (I) formülüne ait bir H+,K+ -ATPase inhibitörüne ait bir sodyum ya da potasyum tuzu ya da bunun tek bir enentiomerinin sodyum ya da potasyum tuzunun bir polietilen glikol çözeltisini kapsayan dayanikli sivi formülasyonlarla ilgilidir. Alternatif olarak H+,K+ -ATPase inhibitörüne ait sodyum ya da potasyum tuzu polietilen glikol çözeltisi yerine sodyum ile potasyum hidroksitin etkin bilesik ile beraber eklenmesi ile de olusturulabilir. Bulus ayni zamanda talep edilen formülasyonun hazirlanmasiyla, dayanikli sivii formülasyonun tipta ve mide bagirsak hastaliklarinin tedavisinde kullanilmasiyla ilgildir.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE9903831A SE9903831D0 (sv) | 1999-10-22 | 1999-10-22 | Formulation of substituted benzimidazoles |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TR200201103T2 true TR200201103T2 (tr) | 2002-08-21 |
Family
ID=20417464
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TR2002/01103T TR200201103T2 (tr) | 1999-10-22 | 2000-10-13 | İkame edilmiş benzimidazol formülasyonları |
Country Status (35)
| Country | Link |
|---|---|
| US (1) | US6730685B1 (tr) |
| EP (1) | EP1274427B1 (tr) |
| JP (1) | JP2003512327A (tr) |
| KR (1) | KR100785603B1 (tr) |
| CN (1) | CN1213751C (tr) |
| AR (1) | AR029005A1 (tr) |
| AT (1) | ATE304851T1 (tr) |
| AU (1) | AU782866B2 (tr) |
| BG (1) | BG65580B1 (tr) |
| BR (1) | BR0014895A (tr) |
| CA (1) | CA2425199C (tr) |
| CO (1) | CO5261533A1 (tr) |
| CY (1) | CY1106055T1 (tr) |
| CZ (1) | CZ20021375A3 (tr) |
| DE (1) | DE60022789T2 (tr) |
| DK (1) | DK1274427T3 (tr) |
| EE (1) | EE05175B1 (tr) |
| ES (1) | ES2246903T3 (tr) |
| HU (1) | HUP0203121A3 (tr) |
| IL (2) | IL149107A0 (tr) |
| IS (1) | IS2196B (tr) |
| MX (1) | MXPA02003900A (tr) |
| MY (1) | MY131971A (tr) |
| NO (1) | NO329545B1 (tr) |
| NZ (1) | NZ518155A (tr) |
| PL (1) | PL199868B1 (tr) |
| RU (1) | RU2286782C2 (tr) |
| SE (1) | SE9903831D0 (tr) |
| SI (1) | SI1274427T1 (tr) |
| SK (1) | SK286266B6 (tr) |
| TR (1) | TR200201103T2 (tr) |
| TW (1) | TWI236372B (tr) |
| UA (1) | UA74347C2 (tr) |
| WO (1) | WO2001028558A1 (tr) |
| ZA (1) | ZA200202905B (tr) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE342263T1 (de) * | 2000-08-04 | 2006-11-15 | Takeda Pharmaceutical | Salze von benzimidazol-derivaten und deren verwendung |
| AU2001278755A1 (en) * | 2000-08-18 | 2002-03-04 | Takeda Chemical Industries Ltd. | Injections |
| MY137726A (en) * | 2000-11-22 | 2009-03-31 | Nycomed Gmbh | Freeze-dried pantoprazole preparation and pantoprazole injection |
| GB2376231A (en) * | 2001-06-06 | 2002-12-11 | Cipla Ltd | Benzimidazole-cyclodextrin inclusion complex |
| FR2845915B1 (fr) * | 2002-10-21 | 2006-06-23 | Negma Gild | Utilisation du tenatoprazole pour le traitement du reflux gastro-oesophagien |
| FR2845916B1 (fr) * | 2002-10-21 | 2006-07-07 | Negma Gild | Composition pharmaceutique associant le tenatoprazole et un antagoniste des recepteurs h2 a l'histamine |
| FR2845917B1 (fr) * | 2002-10-21 | 2006-07-07 | Negma Gild | Composition pharmaceutique associant le tenatoprazole et un anti-inflammatoire |
| FR2848555B1 (fr) * | 2002-12-16 | 2006-07-28 | Negma Gild | Enantiomere(-)du tenatoprazole et son application en therapeutique |
| US7507746B2 (en) * | 2003-02-24 | 2009-03-24 | Mitsubishi Pharma Corporation | Enantiomer of tenatoprazole and the use thereof in therapy |
| TWI372066B (en) * | 2003-10-01 | 2012-09-11 | Wyeth Corp | Pantoprazole multiparticulate formulations |
| US20060089376A1 (en) * | 2004-10-27 | 2006-04-27 | Joshi Ramesh A | Tenatoprazole salts and process of preparation thereof |
| EP2018151A4 (en) * | 2006-05-09 | 2012-07-18 | Astrazeneca Ab | STERILIZED PARENTERAL FORMULATION WITH PROTONED PUMP INHIBITOR BY IONIZING RADIATION IN THE END TANK |
| CN100411613C (zh) * | 2006-12-08 | 2008-08-20 | 中国药科大学 | 一种奥美拉唑速释固体制剂及其制备方法 |
| CN107109464B (zh) | 2014-11-13 | 2021-03-30 | 3M创新有限公司 | 用于检测样品中细菌atp的包含atp-二磷酸水解酶的试剂盒 |
| WO2016174664A1 (en) | 2015-04-29 | 2016-11-03 | Dexcel Pharma Technologies Ltd. | Orally disintegrating compositions |
| US10076494B2 (en) | 2016-06-16 | 2018-09-18 | Dexcel Pharma Technologies Ltd. | Stable orally disintegrating pharmaceutical compositions |
| WO2025078989A1 (en) * | 2023-10-11 | 2025-04-17 | Reena Patel | Stabilized pharmaceutical compositions |
| WO2025181379A1 (en) * | 2024-03-01 | 2025-09-04 | Etico Lifesciences Private Limited | Liquid, storage stable, directly injectable, pantoprazole formulations, their uses and manufacturing |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE7804231L (sv) | 1978-04-14 | 1979-10-15 | Haessle Ab | Magsyrasekretionsmedel |
| SE8301182D0 (sv) * | 1983-03-04 | 1983-03-04 | Haessle Ab | Novel compounds |
| IL75400A (en) | 1984-06-16 | 1988-10-31 | Byk Gulden Lomberg Chem Fab | Dialkoxypyridine methyl(sulfinyl or sulfonyl)benzimidazoles,processes for the preparation thereof and pharmaceutical compositions containing the same |
| JPS6150978A (ja) | 1984-08-16 | 1986-03-13 | Takeda Chem Ind Ltd | ピリジン誘導体およびその製造法 |
| AU4640985A (en) | 1984-08-31 | 1986-03-06 | Nippon Chemiphar Co. Ltd. | Benzimidazole derivatives |
| JP2536173B2 (ja) * | 1988-08-18 | 1996-09-18 | 武田薬品工業株式会社 | 注射剤 |
| DK399389A (da) | 1988-08-18 | 1990-02-19 | Takeda Chemical Industries Ltd | Injicerbare oploesninger |
| KR930000861B1 (ko) | 1990-02-27 | 1993-02-08 | 한미약품공업 주식회사 | 오메프라졸 직장투여 조성물 |
| WO1994002141A1 (en) | 1992-07-28 | 1994-02-03 | Astra Aktiebolag | Injection and injection kit containing omeprazole and its analogs |
| SE9301830D0 (sv) | 1993-05-28 | 1993-05-28 | Ab Astra | New compounds |
| SE9302396D0 (sv) * | 1993-07-09 | 1993-07-09 | Ab Astra | A novel compound form |
| TW359614B (en) | 1993-08-31 | 1999-06-01 | Takeda Chemical Industries Ltd | Composition containing benzimidazole compounds for rectal administration |
| US5726181A (en) | 1995-06-05 | 1998-03-10 | Bionumerik Pharmaceuticals, Inc. | Formulations and compositions of poorly water soluble camptothecin derivatives |
| US5840737A (en) | 1996-01-04 | 1998-11-24 | The Curators Of The University Of Missouri | Omeprazole solution and method for using same |
| US5877205A (en) | 1996-06-28 | 1999-03-02 | Board Of Regents, The University Of Texas System | Parenteral paclitaxel in a stable non-toxic formulation |
| SE510643C2 (sv) | 1997-06-27 | 1999-06-14 | Astra Ab | Termodynamiskt stabil omeprazol natrium form B |
| DE69940769D1 (de) * | 1998-01-20 | 2009-06-04 | Applied Analytical Ind Inc | Orale flüssige zusammensetzungen |
-
1999
- 1999-10-22 SE SE9903831A patent/SE9903831D0/xx unknown
-
2000
- 2000-10-06 AR ARP000105283A patent/AR029005A1/es unknown
- 2000-10-09 TW TW089121063A patent/TWI236372B/zh not_active IP Right Cessation
- 2000-10-13 DK DK00973295T patent/DK1274427T3/da active
- 2000-10-13 DE DE60022789T patent/DE60022789T2/de not_active Expired - Lifetime
- 2000-10-13 EE EEP200200204A patent/EE05175B1/xx not_active IP Right Cessation
- 2000-10-13 SI SI200030759T patent/SI1274427T1/sl unknown
- 2000-10-13 AT AT00973295T patent/ATE304851T1/de active
- 2000-10-13 JP JP2001531388A patent/JP2003512327A/ja active Pending
- 2000-10-13 WO PCT/SE2000/001992 patent/WO2001028558A1/en not_active Ceased
- 2000-10-13 UA UA2002043345A patent/UA74347C2/uk unknown
- 2000-10-13 US US09/701,714 patent/US6730685B1/en not_active Expired - Fee Related
- 2000-10-13 MX MXPA02003900A patent/MXPA02003900A/es active IP Right Grant
- 2000-10-13 TR TR2002/01103T patent/TR200201103T2/tr unknown
- 2000-10-13 ES ES00973295T patent/ES2246903T3/es not_active Expired - Lifetime
- 2000-10-13 PL PL354926A patent/PL199868B1/pl not_active IP Right Cessation
- 2000-10-13 BR BR0014895-4A patent/BR0014895A/pt not_active IP Right Cessation
- 2000-10-13 KR KR1020027005112A patent/KR100785603B1/ko not_active Expired - Fee Related
- 2000-10-13 CN CNB008146373A patent/CN1213751C/zh not_active Expired - Fee Related
- 2000-10-13 RU RU2002110328/15A patent/RU2286782C2/ru not_active IP Right Cessation
- 2000-10-13 NZ NZ518155A patent/NZ518155A/en unknown
- 2000-10-13 IL IL14910700A patent/IL149107A0/xx active IP Right Grant
- 2000-10-13 CA CA2425199A patent/CA2425199C/en not_active Expired - Fee Related
- 2000-10-13 CZ CZ20021375A patent/CZ20021375A3/cs unknown
- 2000-10-13 HU HU0203121A patent/HUP0203121A3/hu unknown
- 2000-10-13 EP EP00973295A patent/EP1274427B1/en not_active Expired - Lifetime
- 2000-10-13 AU AU11823/01A patent/AU782866B2/en not_active Ceased
- 2000-10-13 SK SK539-2002A patent/SK286266B6/sk not_active IP Right Cessation
- 2000-10-19 MY MYPI20004932A patent/MY131971A/en unknown
- 2000-10-19 CO CO00079671A patent/CO5261533A1/es active IP Right Grant
-
2002
- 2002-04-10 BG BG106602A patent/BG65580B1/bg unknown
- 2002-04-11 IL IL149107A patent/IL149107A/en not_active IP Right Cessation
- 2002-04-12 ZA ZA200202905A patent/ZA200202905B/en unknown
- 2002-04-17 IS IS6347A patent/IS2196B/is unknown
- 2002-04-19 NO NO20021860A patent/NO329545B1/no not_active IP Right Cessation
-
2005
- 2005-12-19 CY CY20051101567T patent/CY1106055T1/el unknown
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