TR200100569T2 - Mukozaya yapışan (muko-adhesif) oral sıvı bileşimler - Google Patents
Mukozaya yapışan (muko-adhesif) oral sıvı bileşimlerInfo
- Publication number
- TR200100569T2 TR200100569T2 TR2001/00569T TR200100569T TR200100569T2 TR 200100569 T2 TR200100569 T2 TR 200100569T2 TR 2001/00569 T TR2001/00569 T TR 2001/00569T TR 200100569 T TR200100569 T TR 200100569T TR 200100569 T2 TR200100569 T2 TR 200100569T2
- Authority
- TR
- Turkey
- Prior art keywords
- composition
- oral
- mucosa
- agents
- safe
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 7
- 239000007788 liquid Substances 0.000 title abstract 3
- 230000003232 mucoadhesive effect Effects 0.000 title 1
- 210000004877 mucosa Anatomy 0.000 title 1
- GWEVSGVZZGPLCZ-UHFFFAOYSA-N Titan oxide Chemical compound O=[Ti]=O GWEVSGVZZGPLCZ-UHFFFAOYSA-N 0.000 abstract 2
- 239000003795 chemical substances by application Substances 0.000 abstract 2
- 230000000241 respiratory effect Effects 0.000 abstract 2
- 206010057190 Respiratory tract infections Diseases 0.000 abstract 1
- 206010046306 Upper respiratory tract infection Diseases 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 229940035676 analgesics Drugs 0.000 abstract 1
- 230000000954 anitussive effect Effects 0.000 abstract 1
- 239000000730 antalgic agent Substances 0.000 abstract 1
- 229940125715 antihistaminic agent Drugs 0.000 abstract 1
- 239000000739 antihistaminic agent Substances 0.000 abstract 1
- 239000003434 antitussive agent Substances 0.000 abstract 1
- 229940124584 antitussives Drugs 0.000 abstract 1
- -1 bronsodilators Substances 0.000 abstract 1
- 230000006378 damage Effects 0.000 abstract 1
- 239000000850 decongestant Substances 0.000 abstract 1
- 229940124581 decongestants Drugs 0.000 abstract 1
- 239000003599 detergent Substances 0.000 abstract 1
- 239000003172 expectorant agent Substances 0.000 abstract 1
- 230000003419 expectorant effect Effects 0.000 abstract 1
- 229940066493 expectorants Drugs 0.000 abstract 1
- 229940125695 gastrointestinal agent Drugs 0.000 abstract 1
- 239000004083 gastrointestinal agent Substances 0.000 abstract 1
- 239000003589 local anesthetic agent Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 210000002200 mouth mucosa Anatomy 0.000 abstract 1
- 210000002850 nasal mucosa Anatomy 0.000 abstract 1
- 235000016709 nutrition Nutrition 0.000 abstract 1
- 239000002245 particle Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 210000002345 respiratory system Anatomy 0.000 abstract 1
- 208000020029 respiratory tract infectious disease Diseases 0.000 abstract 1
- 238000004062 sedimentation Methods 0.000 abstract 1
- 230000000451 tissue damage Effects 0.000 abstract 1
- 231100000827 tissue damage Toxicity 0.000 abstract 1
- 239000004408 titanium dioxide Substances 0.000 abstract 1
- 230000001960 triggered effect Effects 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/10—Expectorants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/14—Antitussive agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P23/00—Anaesthetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0043—Nose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0065—Forms with gastric retention, e.g. floating on gastric juice, adhering to gastric mucosa, expanding to prevent passage through the pylorus
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S977/00—Nanotechnology
- Y10S977/902—Specified use of nanostructure
- Y10S977/904—Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
- Y10S977/915—Therapeutic or pharmaceutical composition
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Pulmonology (AREA)
- Inorganic Chemistry (AREA)
- Anesthesiology (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Otolaryngology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Developing Agents For Electrophotography (AREA)
- Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
Abstract
Mevcut bulus, bilesimin agirligina göre yaklasik %2 ila yaklasik %50 titanyum dioksit koloidal parçaciklari ve mide-bagirsak maddeleri, analjezikler, dekonjestanlar, ekspektoranlar, antitüsifler, antihistaminler, bronsodilatörler, topikal anestetikler, algi maddeleri, oral bakim maddeleri, çesitli solunum maddeleri, ve bunlarin karisimindan olusan gruptan seçilen bir farmasötik aktif maddenin güvenli ve etkili miktarini içeren bir oral veya oral mukozada tutunan sulu sivi farmasötik bilesim ile ilgilidir; ki burada bilesim yaklasik 48 saat sonra ölçülen yaklasik 0.90'dan daha büyük bir çökme hacmi oranina sahiptir ve bilesimin tetiklenmis viskozite orani en az yaklasik 1.2'dir. Mevcut bulus ayrica, yukaridaki bilesimin güvenli ve etkili bir miktarinin uygulanmasi ile, beslenme kanali veya nasal mukozanin kaplanmasi, özellikle üst solunum sistemi enfeksiyonlari ve üst solunum sistemi doku tahrisi ve tahribinin önlenmesi ve tedavi edilmesi için bir yöntemle ilgilidir.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US9764698P | 1998-08-24 | 1998-08-24 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TR200100569T2 true TR200100569T2 (tr) | 2001-07-23 |
Family
ID=22264456
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TR2001/00569T TR200100569T2 (tr) | 1998-08-24 | 1999-08-24 | Mukozaya yapışan (muko-adhesif) oral sıvı bileşimler |
Country Status (18)
| Country | Link |
|---|---|
| US (2) | US20020009478A1 (tr) |
| EP (1) | EP1107732B1 (tr) |
| JP (1) | JP2002523353A (tr) |
| KR (1) | KR20010074834A (tr) |
| CN (1) | CN1313754A (tr) |
| AT (1) | ATE227978T1 (tr) |
| AU (1) | AU753251B2 (tr) |
| BR (1) | BR9913148A (tr) |
| CA (1) | CA2338480C (tr) |
| CO (1) | CO5140074A1 (tr) |
| DE (1) | DE69904057T2 (tr) |
| DK (1) | DK1107732T3 (tr) |
| ES (1) | ES2185395T3 (tr) |
| HU (1) | HUP0103217A2 (tr) |
| NO (1) | NO20010830L (tr) |
| PE (1) | PE20000863A1 (tr) |
| TR (1) | TR200100569T2 (tr) |
| WO (1) | WO2000010528A1 (tr) |
Families Citing this family (60)
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| US20020009478A1 (en) * | 1998-08-24 | 2002-01-24 | Douglas Joseph Dobrozsi | Oral liquid mucoadhesive compositions |
| US7544348B2 (en) * | 2001-02-15 | 2009-06-09 | Access Pharmaceuticals, Inc. | Liquid formulations for the prevention and treatment of mucosal diseases and disorders |
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| AU2003222990B2 (en) * | 2002-05-02 | 2009-11-12 | Cragmont Pharmaceuticals, Llc | Therapeutic 1,2,3,6-tetrahydropyrimidine-2-one compositions and methods therewith |
| HUE033319T2 (en) * | 2002-06-28 | 2017-11-28 | Civitas Therapeutics Inc | Inhalation epinephrine |
| US6669929B1 (en) | 2002-12-30 | 2003-12-30 | Colgate Palmolive Company | Dentifrice containing functional film flakes |
| US20050058672A1 (en) * | 2003-09-14 | 2005-03-17 | Bioderm Research | Baby Care Skin Protectant Compositions for Diaper Rash |
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| US8497258B2 (en) | 2005-11-12 | 2013-07-30 | The Regents Of The University Of California | Viscous budesonide for the treatment of inflammatory diseases of the gastrointestinal tract |
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| US5658553A (en) * | 1995-05-02 | 1997-08-19 | The Procter & Gamble Company | Dentifrice compositions |
| US6184220B1 (en) * | 1998-03-27 | 2001-02-06 | Boehringer Ingelheim Pharma Kg | Oral suspension of pharmaceutical substance |
| US20020009478A1 (en) * | 1998-08-24 | 2002-01-24 | Douglas Joseph Dobrozsi | Oral liquid mucoadhesive compositions |
-
1999
- 1999-07-27 US US09/361,542 patent/US20020009478A1/en not_active Abandoned
- 1999-08-24 HU HU0103217A patent/HUP0103217A2/hu unknown
- 1999-08-24 WO PCT/US1999/019201 patent/WO2000010528A1/en not_active Ceased
- 1999-08-24 CA CA002338480A patent/CA2338480C/en not_active Expired - Fee Related
- 1999-08-24 CO CO99053435A patent/CO5140074A1/es unknown
- 1999-08-24 BR BR9913148-0A patent/BR9913148A/pt not_active IP Right Cessation
- 1999-08-24 TR TR2001/00569T patent/TR200100569T2/tr unknown
- 1999-08-24 DE DE69904057T patent/DE69904057T2/de not_active Expired - Lifetime
- 1999-08-24 PE PE1999000850A patent/PE20000863A1/es not_active Application Discontinuation
- 1999-08-24 CN CN99809845A patent/CN1313754A/zh active Pending
- 1999-08-24 AU AU55808/99A patent/AU753251B2/en not_active Ceased
- 1999-08-24 JP JP2000565850A patent/JP2002523353A/ja not_active Withdrawn
- 1999-08-24 AT AT99942428T patent/ATE227978T1/de not_active IP Right Cessation
- 1999-08-24 ES ES99942428T patent/ES2185395T3/es not_active Expired - Lifetime
- 1999-08-24 DK DK99942428T patent/DK1107732T3/da active
- 1999-08-24 KR KR1020017001962A patent/KR20010074834A/ko not_active Ceased
- 1999-08-24 EP EP99942428A patent/EP1107732B1/en not_active Expired - Lifetime
-
2001
- 2001-02-19 NO NO20010830A patent/NO20010830L/no not_active Application Discontinuation
- 2001-12-07 US US10/021,327 patent/US6638521B2/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| KR20010074834A (ko) | 2001-08-09 |
| CO5140074A1 (es) | 2002-03-22 |
| DE69904057D1 (de) | 2003-01-02 |
| US20020009478A1 (en) | 2002-01-24 |
| US6638521B2 (en) | 2003-10-28 |
| WO2000010528A1 (en) | 2000-03-02 |
| ATE227978T1 (de) | 2002-12-15 |
| ES2185395T3 (es) | 2003-04-16 |
| PE20000863A1 (es) | 2000-09-12 |
| CA2338480C (en) | 2004-10-05 |
| AU5580899A (en) | 2000-03-14 |
| BR9913148A (pt) | 2001-09-25 |
| DE69904057T2 (de) | 2003-08-21 |
| US20020076421A1 (en) | 2002-06-20 |
| NO20010830D0 (no) | 2001-02-19 |
| NO20010830L (no) | 2001-02-19 |
| CA2338480A1 (en) | 2000-03-02 |
| EP1107732B1 (en) | 2002-11-20 |
| AU753251B2 (en) | 2002-10-10 |
| CN1313754A (zh) | 2001-09-19 |
| HUP0103217A2 (hu) | 2001-12-28 |
| DK1107732T3 (da) | 2003-03-17 |
| EP1107732A1 (en) | 2001-06-20 |
| JP2002523353A (ja) | 2002-07-30 |
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