TR200003171T2 - 1 - [(1-substituted-4-piperidinyl) methyl] -4-piperidine derivative, preparation process, pharmaceutical composition and intermediate containing this derivative - Google Patents
1 - [(1-substituted-4-piperidinyl) methyl] -4-piperidine derivative, preparation process, pharmaceutical composition and intermediate containing this derivativeInfo
- Publication number
- TR200003171T2 TR200003171T2 TR2000/03171T TR200003171T TR200003171T2 TR 200003171 T2 TR200003171 T2 TR 200003171T2 TR 2000/03171 T TR2000/03171 T TR 2000/03171T TR 200003171 T TR200003171 T TR 200003171T TR 200003171 T2 TR200003171 T2 TR 200003171T2
- Authority
- TR
- Turkey
- Prior art keywords
- derivative
- pharmaceutical composition
- piperidinyl
- substituted
- methyl
- Prior art date
Links
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 238000002360 preparation method Methods 0.000 title abstract 2
- -1 1-substituted-4-piperidinyl Chemical group 0.000 title 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 title 1
- 239000012450 pharmaceutical intermediate Substances 0.000 title 1
- 108091005482 5-HT4 receptors Proteins 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000003623 enhancer Substances 0.000 abstract 1
- 230000002496 gastric effect Effects 0.000 abstract 1
- 230000005176 gastrointestinal motility Effects 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Landscapes
- Hydrogenated Pyridines (AREA)
Abstract
Ar'nin formül (Ar-1) veya (Ar-2) nin: bir grubu A'nin bir formül -Z-N(Q1)(Q2),-CO-R7 veya -(CH2)P-CH(R8)-COR grubu oldugu formül (I): Bilesimi, farmasötik olarak kabul edilebilir bir asit katki tuzunu, bunun hazirlanmasi için bir proses ve bunu içeren bir farmasötik terkip. Bulus bilesimleri 5-HT4 reseptörleri için güçlü bir egilimi gösterirler ve mide bagirsak hareket kabiliyetini artirici veya bir mide bagirsak prokimetik maddesi olarak faydalidirlar.Ar's formula (Ar-1) or (Ar-2): a group of A is a formula -ZN (Q1) (Q2), - CO-R7 or - (CH2) P-CH (R8) -COR Formula (I): The composition is a pharmaceutically acceptable acid addition salt, a process for its preparation and a pharmaceutical composition containing it. Invention compounds show a strong tendency for 5-HT4 receptors and are useful as a gastrointestinal motility enhancer or as a gastrointestinal prochetic agent.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP45041998 | 1998-04-28 | ||
| JP50191998 | 1998-06-24 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TR200003171T2 true TR200003171T2 (en) | 2001-03-21 |
Family
ID=26583097
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TR2000/03171T TR200003171T2 (en) | 1998-04-28 | 1999-04-19 | 1 - [(1-substituted-4-piperidinyl) methyl] -4-piperidine derivative, preparation process, pharmaceutical composition and intermediate containing this derivative |
Country Status (1)
| Country | Link |
|---|---|
| TR (1) | TR200003171T2 (en) |
-
1999
- 1999-04-19 TR TR2000/03171T patent/TR200003171T2/en unknown
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