TR200002969T2 - Farmasötik bileşim. - Google Patents
Farmasötik bileşim.Info
- Publication number
- TR200002969T2 TR200002969T2 TR2000/02969T TR200002969T TR200002969T2 TR 200002969 T2 TR200002969 T2 TR 200002969T2 TR 2000/02969 T TR2000/02969 T TR 2000/02969T TR 200002969 T TR200002969 T TR 200002969T TR 200002969 T2 TR200002969 T2 TR 200002969T2
- Authority
- TR
- Turkey
- Prior art keywords
- pharmaceutical composition
- medicament
- human
- manufacture
- compound
- Prior art date
Links
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 230000006028 immune-suppresssive effect Effects 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7076—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7076—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid
- A61K31/708—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid having oxo groups directly attached to the purine ring system, e.g. guanosine, guanylic acid
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
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- A—HUMAN NECESSITIES
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- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61P35/00—Antineoplastic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
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- A—HUMAN NECESSITIES
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- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
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- A—HUMAN NECESSITIES
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- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Pulmonology (AREA)
- Dermatology (AREA)
- Oncology (AREA)
- Urology & Nephrology (AREA)
- Virology (AREA)
- Rheumatology (AREA)
- Ophthalmology & Optometry (AREA)
- Endocrinology (AREA)
- Obesity (AREA)
- AIDS & HIV (AREA)
- Tropical Medicine & Parasitology (AREA)
- Emergency Medicine (AREA)
- Pain & Pain Management (AREA)
- Communicable Diseases (AREA)
- Neurosurgery (AREA)
- Gastroenterology & Hepatology (AREA)
- Neurology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Biomedical Technology (AREA)
Abstract
Bu bulus (I) formüllü bir terkibin veya farmasötik olarak kabul edilebilir bir tuzunun insan veya hayvan vücuduna bagisiklik baskilayici bir tedavi uygulamak için bir ilacin imalatinda kullanimini temin eder.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AT63698 | 1998-04-14 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TR200002969T2 true TR200002969T2 (tr) | 2001-01-22 |
Family
ID=3495843
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TR2000/02969T TR200002969T2 (tr) | 1998-04-14 | 1999-04-14 | Farmasötik bileşim. |
| TR2001/01633T TR200101633T2 (tr) | 1998-04-14 | 1999-04-14 | Farmasötik bileşim |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TR2001/01633T TR200101633T2 (tr) | 1998-04-14 | 1999-04-14 | Farmasötik bileşim |
Country Status (27)
| Country | Link |
|---|---|
| US (1) | US6555518B1 (tr) |
| EP (1) | EP1071433B1 (tr) |
| JP (1) | JP2002511405A (tr) |
| KR (1) | KR100450248B1 (tr) |
| CN (1) | CN1312719A (tr) |
| AR (1) | AR019053A1 (tr) |
| AT (1) | ATE229338T1 (tr) |
| AU (1) | AU3126799A (tr) |
| BR (1) | BR9909617A (tr) |
| CA (1) | CA2327431A1 (tr) |
| CO (1) | CO5011041A1 (tr) |
| DE (1) | DE59903751D1 (tr) |
| DK (1) | DK1071433T3 (tr) |
| EA (1) | EA200001061A1 (tr) |
| ES (1) | ES2190647T3 (tr) |
| HU (1) | HUP0102671A3 (tr) |
| ID (1) | ID27201A (tr) |
| IL (2) | IL138888A0 (tr) |
| NO (1) | NO20005179L (tr) |
| PE (1) | PE20000424A1 (tr) |
| PL (1) | PL343769A1 (tr) |
| PT (1) | PT1071433E (tr) |
| SV (1) | SV1999000039A (tr) |
| TR (2) | TR200002969T2 (tr) |
| TW (1) | TW466112B (tr) |
| WO (1) | WO1999052514A2 (tr) |
| ZA (1) | ZA200005510B (tr) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATA173599A (de) * | 1999-10-14 | 2001-04-15 | Lilly Co Eli | Pharmazeutisches produkt |
| MY164523A (en) * | 2000-05-23 | 2017-12-29 | Univ Degli Studi Cagliari | Methods and compositions for treating hepatitis c virus |
| MXPA02011691A (es) | 2000-05-26 | 2004-05-17 | Idenix Cayman Ltd | Metodos y composiciones para el tratamiento de flavivirus y pestivirus. |
| TWI296196B (en) * | 2001-04-06 | 2008-05-01 | Wyeth Corp | Antineoplastic combinations |
| EA010184B1 (ru) * | 2001-04-06 | 2008-06-30 | Уайт | Применение противоопухолевых комбинаций рапамицина с гемцитабином или 5-фторурацилом |
| TWI233359B (en) * | 2001-04-06 | 2005-06-01 | Wyeth Corp | Pharmaceutical composition for treating neoplasm |
| US20020198137A1 (en) * | 2001-06-01 | 2002-12-26 | Wyeth | Antineoplastic combinations |
| JP2005522443A (ja) * | 2002-02-14 | 2005-07-28 | フアーマセツト・リミテツド | 改変フッ素化ヌクレオシド類似体 |
| CN101172993A (zh) | 2002-06-28 | 2008-05-07 | 埃迪尼克斯(开曼)有限公司 | 用于治疗黄病毒感染的2′-c-甲基-3′-o-l-缬氨酸酯核糖呋喃基胞苷 |
| PL377342A1 (pl) | 2002-11-15 | 2006-01-23 | Idenix (Cayman) Limited | Nukleozydy rozgałęzione w pozycji 2' oraz mutacja Flaviviridae |
| AU2003300901A1 (en) | 2002-12-12 | 2004-06-30 | Idenix (Cayman) Limited | Process for the production of 2'-branched nucleosides |
| DE10323278A1 (de) * | 2003-05-21 | 2004-12-16 | Stada Arzneimittel Ag | Gebrauchsfertige Gemcitabin-Lösungskonzentrate |
| DE10323279A1 (de) * | 2003-05-21 | 2004-12-16 | Stada Arzneimittel Ag | Gebrauchsfertige Gemcitabin-Lösungen |
| AU2005329287B2 (en) * | 2005-03-17 | 2011-01-27 | Proyecto De Biomedicina Cima S.L. | Use of 5'-methylthioadenosine (MTA) in the prevention and/or treatment of autoimmune diseases and/or transplant rejection |
| ES2259552B1 (es) * | 2005-03-17 | 2007-06-16 | Proyecto De Biomedicina Cima, S.L. | Empleo de 5'-metiltioadenosina (mta) en la prevencion y/o tratamiento de enfermedades autoinmunes y/o rechazo de transplantes. |
| AT502221A1 (de) * | 2005-07-20 | 2007-02-15 | Pharmacon Forschung & Beratung Gmbh | Homogemcitabine, verfahren zu ihrer herstellung sowie deren verwendung |
| WO2010118006A1 (en) | 2009-04-06 | 2010-10-14 | Eisai Inc. | (2 ' -deoxy-ribofuranosyl) -1,3,4, 7-tetrahydro- (1,3) iazepin-2-0ne derivatives for treating cancer |
| US9913822B2 (en) | 2012-04-04 | 2018-03-13 | Halozyme, Inc. | Combination therapy with an anti-hyaluronan agent and therapeutic agent |
| CN107184592A (zh) * | 2017-05-17 | 2017-09-22 | 广东艾时代生物科技有限责任公司 | 吉西他滨在制备治疗类风湿性关节炎药物中的应用 |
| WO2019222435A1 (en) | 2018-05-16 | 2019-11-21 | Halozyme, Inc. | Methods of selecting subjects for combination cancer therapy with a polymer-conjugated soluble ph20 |
| AU2019296174B2 (en) | 2018-06-29 | 2021-10-07 | Changchun Changcheng Pharmaceutical Technology Co., LTD | Phosphorus-containing prodrugs of gemcitabine |
| RU2764742C1 (ru) * | 2021-04-09 | 2022-01-20 | Федеральное государственное бюджетное учреждение "Национальный медицинский исследовательский центр трансплантологии и искусственных органов имени академика В.И. Шумакова" Министерства здравоохранения Российской Федерации (ФГБУ "НМИЦ ТИО им. академика В.И. Шумакова" Минздрава России) | Способ подбора режима иммуносупрессии детям раннего возраста в отдаленном периоде после трансплантации печени |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4526988A (en) * | 1983-03-10 | 1985-07-02 | Eli Lilly And Company | Difluoro antivirals and intermediate therefor |
| DE3587500T2 (de) * | 1984-12-04 | 1993-12-16 | Lilly Co Eli | Tumorbehandlung bei Säugetieren. |
| US4914028A (en) * | 1988-02-10 | 1990-04-03 | Eli Lilly And Company | Method of preparing beta-2',2'-difluoronucleosides |
| JPH0232093A (ja) * | 1988-06-08 | 1990-02-01 | Merrell Dow Pharmaceut Inc | 抗レトロウィルスジフルオロ化ヌクレオシド類 |
| AU4134793A (en) * | 1992-06-22 | 1993-12-23 | Eli Lilly And Company | 2'-deoxy-2',2'-difluoro(2,6,8-substituted) purine nucleosides having anti-viral and anti-cancer activity and intermediates |
| US6291504B1 (en) * | 1999-10-20 | 2001-09-18 | Dupont Pharmaceuticals Company | Acylsemicarbazides and their uses |
-
1999
- 1999-04-09 TW TW088105804A patent/TW466112B/zh active
- 1999-04-12 PE PE1999000297A patent/PE20000424A1/es not_active Application Discontinuation
- 1999-04-13 AR ARP990101686A patent/AR019053A1/es unknown
- 1999-04-13 SV SV1999000039A patent/SV1999000039A/es unknown
- 1999-04-13 CO CO99021850A patent/CO5011041A1/es unknown
- 1999-04-14 TR TR2000/02969T patent/TR200002969T2/tr unknown
- 1999-04-14 WO PCT/AT1999/000093 patent/WO1999052514A2/de not_active Ceased
- 1999-04-14 EP EP99912962A patent/EP1071433B1/de not_active Expired - Lifetime
- 1999-04-14 PL PL99343769A patent/PL343769A1/xx unknown
- 1999-04-14 BR BR9909617-0A patent/BR9909617A/pt not_active Application Discontinuation
- 1999-04-14 EA EA200001061A patent/EA200001061A1/ru unknown
- 1999-04-14 JP JP2000543124A patent/JP2002511405A/ja active Pending
- 1999-04-14 AU AU31267/99A patent/AU3126799A/en not_active Abandoned
- 1999-04-14 DE DE59903751T patent/DE59903751D1/de not_active Expired - Fee Related
- 1999-04-14 PT PT99912962T patent/PT1071433E/pt unknown
- 1999-04-14 TR TR2001/01633T patent/TR200101633T2/tr unknown
- 1999-04-14 DK DK99912962T patent/DK1071433T3/da active
- 1999-04-14 AT AT99912962T patent/ATE229338T1/de not_active IP Right Cessation
- 1999-04-14 CA CA002327431A patent/CA2327431A1/en not_active Abandoned
- 1999-04-14 IL IL13888899A patent/IL138888A0/xx unknown
- 1999-04-14 ID IDW20002331A patent/ID27201A/id unknown
- 1999-04-14 ES ES99912962T patent/ES2190647T3/es not_active Expired - Lifetime
- 1999-04-14 CN CN99807371A patent/CN1312719A/zh active Pending
- 1999-04-14 KR KR10-2000-7011402A patent/KR100450248B1/ko not_active Expired - Fee Related
- 1999-04-14 HU HU0102671A patent/HUP0102671A3/hu unknown
-
2000
- 2000-10-05 IL IL138888A patent/IL138888A/en not_active IP Right Cessation
- 2000-10-09 ZA ZA200005510A patent/ZA200005510B/xx unknown
- 2000-10-13 US US09/687,565 patent/US6555518B1/en not_active Expired - Fee Related
- 2000-10-13 NO NO20005179A patent/NO20005179L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| ID27201A (id) | 2001-03-08 |
| AR019053A1 (es) | 2001-12-26 |
| CN1312719A (zh) | 2001-09-12 |
| EP1071433B1 (de) | 2002-12-11 |
| TR200101633T2 (tr) | 2002-06-21 |
| SV1999000039A (es) | 1999-11-25 |
| KR100450248B1 (ko) | 2004-09-24 |
| HUP0102671A2 (hu) | 2001-12-28 |
| NO20005179D0 (no) | 2000-10-13 |
| PT1071433E (pt) | 2003-04-30 |
| BR9909617A (pt) | 2000-12-12 |
| EP1071433A2 (de) | 2001-01-31 |
| JP2002511405A (ja) | 2002-04-16 |
| WO1999052514A3 (de) | 2000-07-06 |
| ES2190647T3 (es) | 2003-08-01 |
| AU3126799A (en) | 1999-11-01 |
| TW466112B (en) | 2001-12-01 |
| NO20005179L (no) | 2000-10-13 |
| KR20010034779A (ko) | 2001-04-25 |
| PL343769A1 (en) | 2001-09-10 |
| WO1999052514A2 (de) | 1999-10-21 |
| PE20000424A1 (es) | 2000-05-19 |
| DE59903751D1 (de) | 2003-01-23 |
| CO5011041A1 (es) | 2001-02-28 |
| HUP0102671A3 (en) | 2002-04-29 |
| IL138888A (en) | 2009-05-04 |
| EA200001061A1 (ru) | 2001-04-23 |
| DK1071433T3 (da) | 2003-04-07 |
| IL138888A0 (en) | 2001-11-25 |
| ZA200005510B (en) | 2001-05-08 |
| US6555518B1 (en) | 2003-04-29 |
| ATE229338T1 (de) | 2002-12-15 |
| CA2327431A1 (en) | 1999-10-21 |
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