[go: up one dir, main page]

TR200001709T2 - Yeni neisseria meningitids yüzey proteini - Google Patents

Yeni neisseria meningitids yüzey proteini

Info

Publication number
TR200001709T2
TR200001709T2 TR2000/01709T TR200001709T TR200001709T2 TR 200001709 T2 TR200001709 T2 TR 200001709T2 TR 2000/01709 T TR2000/01709 T TR 2000/01709T TR 200001709 T TR200001709 T TR 200001709T TR 200001709 T2 TR200001709 T2 TR 200001709T2
Authority
TR
Turkey
Prior art keywords
new
surface protein
neisseria
meningitids
nucleic acid
Prior art date
Application number
TR2000/01709T
Other languages
English (en)
Inventor
Richard Anselm Peak Ian
Paul Jennings Michael
E. Moxon Richard
Original Assignee
The Universty Of Queensland
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10823587&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=TR200001709(T2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by The Universty Of Queensland filed Critical The Universty Of Queensland
Publication of TR200001709T2 publication Critical patent/TR200001709T2/tr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/22—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Neisseriaceae (F)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Plant Pathology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Oncology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

Bulus, Neisseria meningitidis den yeni bir yüzey polipeptidi ile bu proteini kodlayan nükleik asit ve nükleik asit sekansi homologlari saglar. Bulusun polipeptidini ve nükleik asitlerini içeren farmasötik terkipler ve Neisseria meningitidis enfeksiyonu tedavisi, önlenmesi ve teshisinde kullanilabilecek yöntemle de açiklanmistir.
TR2000/01709T 1997-12-12 1998-12-14 Yeni neisseria meningitids yüzey proteini TR200001709T2 (tr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9726398.2A GB9726398D0 (en) 1997-12-12 1997-12-12 Polypeptide and coding sequences

Publications (1)

Publication Number Publication Date
TR200001709T2 true TR200001709T2 (tr) 2001-03-21

Family

ID=10823587

Family Applications (1)

Application Number Title Priority Date Filing Date
TR2000/01709T TR200001709T2 (tr) 1997-12-12 1998-12-14 Yeni neisseria meningitids yüzey proteini

Country Status (17)

Country Link
US (8) US6197312B1 (tr)
EP (2) EP1045859A4 (tr)
JP (2) JP4356961B2 (tr)
KR (1) KR100571533B1 (tr)
CN (2) CN1284965A (tr)
AU (1) AU747742B2 (tr)
BR (1) BR9814276A (tr)
CA (1) CA2314319C (tr)
CZ (1) CZ299646B6 (tr)
GB (1) GB9726398D0 (tr)
HU (1) HUP0100094A3 (tr)
IL (2) IL136684A0 (tr)
NO (1) NO20002990L (tr)
NZ (1) NZ505374A (tr)
PL (1) PL205984B1 (tr)
TR (1) TR200001709T2 (tr)
WO (1) WO1999031132A1 (tr)

Families Citing this family (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9726398D0 (en) 1997-12-12 1998-02-11 Isis Innovation Polypeptide and coding sequences
ES2333071T5 (es) * 1998-01-14 2015-08-17 Novartis Vaccines And Diagnostics S.R.L. Antígenos de Neisseria meningitidis
FR2776928B1 (fr) * 1998-04-03 2000-06-23 Merial Sas Vaccins adn adjuves
BR9910089A (pt) 1998-05-01 2004-06-08 Chiron Corp Composições e antìgenos de neisseria meningitidis
GB9810276D0 (en) * 1998-05-13 1998-07-15 Smithkline Beecham Biolog Novel compounds
AU2004240199B2 (en) * 1999-04-30 2007-05-17 Novartis Vaccines And Diagnostics S.R.L. Conserved Neisserial antigens
WO2000066741A2 (en) * 1999-04-30 2000-11-09 Chiron S.P.A. Conserved neisserial antigens
EP1173578A2 (en) * 1999-05-04 2002-01-23 Monsanto Company Coleopteran-toxic polypeptide compositions and insect-resistant transgenic plants
ES2563650T3 (es) * 1999-05-19 2016-03-15 Glaxosmithkline Biologicals Sa Composiciones de combinaciones de Neisseria
GB9916529D0 (en) * 1999-07-14 1999-09-15 Chiron Spa Antigenic peptides
GB9918319D0 (en) 1999-08-03 1999-10-06 Smithkline Beecham Biolog Vaccine composition
EP2275553B1 (en) * 1999-10-29 2015-05-13 Novartis Vaccines and Diagnostics S.r.l. Neisserial antigenic peptides
BR0015961A (pt) 1999-11-29 2003-06-10 Chiron Spa Antìgeno de neisseria de 85kda
GB9928196D0 (en) * 1999-11-29 2000-01-26 Chiron Spa Combinations of B, C and other antigens
PT1248647E (pt) 2000-01-17 2010-11-18 Novartis Vaccines & Diagnostics Srl Vacina de vesícula da membrana externa (omv) compreendendo proteínas de membrana externa de n. meningitidis do serogrupo b
AU2005202972B2 (en) * 2000-01-25 2008-04-24 The University Of Queensland Proteins comprising conserved regions of neisseria meningitidis surface antigen NhhA
PL216780B1 (pl) * 2000-01-25 2014-05-30 Univ Queensland Of Santa Lucia Wyizolowane białka zawierające konserwatywne obszary antygenu powierzchniowego NhhA z Neisseria meningitidis, białka fuzyjne, kompozycja farmaceutyczna, przeciwciało monoklonalne lub wiążący antygen fragment przeciwciała monoklonalnego, wyizolowany kwas nukleinowy, konstrukt ekspresyjny, komórka gospodarza, sposób wytwarzania rekombinowanego białka, sposób wykrywania N. meningitidis w próbce biologicznej, sposób diagnozowania zakażenia N. meningitidis oraz sposób wykrywania N. meningitidis w próbce biologicznej uzyskanej od pacjenta oraz zastosowanie wyizolowanego białka, białka fuzyjnego i konstruktu ekspresyjnego
ES2299476T3 (es) 2000-02-28 2008-06-01 Novartis Vaccines And Diagnostics S.R.L. Expresion hibrida de proteinas de neisseria.
NO20002828D0 (no) * 2000-06-02 2000-06-02 Statens Inst For Folkehelse Proteinholdig vaksine mot Neisseria meningtidis serogruppe samt fremgangsmÕte ved fremstilling derav
GB0103171D0 (en) 2001-02-08 2001-03-28 Smithkline Beecham Biolog Vaccine composition
GB0121591D0 (en) 2001-09-06 2001-10-24 Chiron Spa Hybrid and tandem expression of neisserial proteins
BR0211494A (pt) 2001-07-27 2004-08-17 Chiron Srl Adesinas de meningococo nada, app e orf 40
GB0129007D0 (en) * 2001-12-04 2002-01-23 Chiron Spa Adjuvanted antigenic meningococcal compositions
EP1524992B1 (en) * 2002-08-02 2015-03-04 GlaxoSmithKline Biologicals s.a. Vaccine compositions comprising l2 and/or l3 immunotype lipooligosaccharides from lgtb- neisseria menigitidis
BR0313100A (pt) * 2002-08-02 2005-06-21 Glaxosmithkline Biolog Sa Composição imunogênica, composição imunogênica isolada, vacina, método de tratamento ou prevenção de doença bacteriana gram-negativa, uso da vacina, cepa bacteriana gram-negativa geneticamente manipulada, método para preparar a composição imunogênica, método para preparar a vacina, método de preparar uma imunoglobulina para uso na prevenção ou tratamento de infecção neisserial, preparação de imunoglobulina, preparação farmacêutica, e, uso da preparação farmacêutica
EP1549338B1 (en) 2002-10-11 2010-12-22 Novartis Vaccines and Diagnostics S.r.l. Polypeptide-vaccines for broad protection against hypervirulent meningococcal lineages
AU2003287980B2 (en) 2002-11-01 2009-06-25 Glaxosmithkline Biologicals S.A. Drying process
EP1667712B1 (en) 2003-10-02 2010-07-21 GlaxoSmithKline Biologicals S.A. B. pertussis antigens and use thereof in vaccination
PL1670506T3 (pl) 2003-10-02 2013-04-30 Novartis Ag Płynne szczepionki przeciw wielu grupom serologicznym meningokoków
GB0408977D0 (en) 2004-04-22 2004-05-26 Chiron Srl Immunising against meningococcal serogroup Y using proteins
GB0505996D0 (en) 2005-03-23 2005-04-27 Glaxosmithkline Biolog Sa Fermentation process
TW200800235A (en) 2005-10-18 2008-01-01 Otsuka Pharma Co Ltd Carrier composition for nucleic acid transport
US20090123499A1 (en) 2006-06-12 2009-05-14 Nathalie Devos Vaccine
GB0700562D0 (en) 2007-01-11 2007-02-21 Novartis Vaccines & Diagnostic Modified Saccharides
MX2010003501A (es) * 2007-10-04 2010-06-09 Bio Architecture Lab Inc Produccion de biocombustible.
EP2211805B1 (en) * 2007-11-19 2011-08-17 The Procter & Gamble Company Process for activating a web
JP2011510634A (ja) * 2008-01-28 2011-04-07 ビオ アルチテクトウレ ラブ インコーポレイテッド 単離されたアルコールデヒドロゲナーゼ酵素、及びその使用
AU2009262893B2 (en) 2008-05-30 2015-05-21 The U.S.A., as represented by The Secretary of the Army, on behalf of Walter Reed Army Institute Of Research Meningococcal multivalent native outer membrane vesicle vaccine, methods of making and use thereof
US20130004530A1 (en) 2010-03-10 2013-01-03 Jan Poolman Vaccine composition
JP2013522177A (ja) 2010-03-11 2013-06-13 グラクソスミスクライン バイオロジカルズ ソシエテ アノニム グラム陰性細菌性、例えば髄膜炎菌性の感染または疾患に対する免疫原性組成物またはワクチン
GB201015132D0 (en) * 2010-09-10 2010-10-27 Univ Bristol Vaccine composition
AU2011300418B2 (en) 2010-09-10 2016-05-12 Glaxosmithkline Biologicals Sa Meningococcus overexpressing NadA and/or NHBA and outer membrane vesicles derived therefrom
NZ630133A (en) 2012-06-14 2016-10-28 Novartis Ag Vaccines for serogroup x meningococcus
CZ304288B6 (cs) * 2013-06-12 2014-02-12 Rieter Cz S.R.O. Způsob a zařízení ke sledování lineárního útvaru

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4843000A (en) 1979-12-26 1989-06-27 Syntex (U.S.A.) Inc. Simultaneous calibration heterogeneous immunoassay
US4849338A (en) 1982-07-16 1989-07-18 Syntex (U.S.A.) Inc. Simultaneous calibration heterogeneous immunoassay
US4550081A (en) 1980-05-19 1985-10-29 The Board Of Trustees Of The Leland Stanford Jr. University Non-reverting salmonella
US4366241A (en) 1980-08-07 1982-12-28 Syva Company Concentrating zone method in heterogeneous immunoassays
US4769240A (en) * 1980-09-15 1988-09-06 Bactex, Inc. Pili of neisseria and vaccine compositions containing same
US4722848A (en) 1982-12-08 1988-02-02 Health Research, Incorporated Method for immunizing animals with synthetically modified vaccinia virus
US4603112A (en) 1981-12-24 1986-07-29 Health Research, Incorporated Modified vaccinia virus
US4702911A (en) * 1985-09-27 1987-10-27 Immunomed Corporation Preparation of bacterium pili subunits and vaccines containing pili subunits
GB8607679D0 (en) 1986-03-27 1986-04-30 Winter G P Recombinant dna product
US5091513A (en) 1987-05-21 1992-02-25 Creative Biomolecules, Inc. Biosynthetic antibody binding sites
RU2023448C1 (ru) 1987-07-30 1994-11-30 Сентро Насьональ Де Биопрепарадос Способ получения вакцины против различных патогенных серотипов менингита нейссера группы в
US5785973A (en) 1988-02-01 1998-07-28 Praxis Biologics, Inc. Synthetic peptides representing a T-cell epitope as a carrier molecule for conjugate vaccines
EP0407413B1 (de) 1988-03-24 1992-06-03 ZACH, Johann Druck- oder kraftmessvorrichtung
DE69133334T2 (de) * 1990-08-23 2004-05-13 University Of North Carolina At Chapel Hill Transferrin bindende proteine aus neisseria-gonorrhoeae und neisseria-meningitidis
FR2682041B1 (fr) * 1991-10-03 1994-01-14 Pasteur Merieux Serums Vaccins Vaccin contre les infections a neisseria meningitidis.
US5422252A (en) 1993-06-04 1995-06-06 Becton, Dickinson And Company Simultaneous amplification of multiple targets
IL117483A (en) * 1995-03-17 2008-03-20 Bernard Brodeur MENINGITIDIS NEISSERIA shell protein is resistant to proteinase K.
US5646259A (en) * 1995-03-24 1997-07-08 St. Louis University DNA encoding haemophilus adhesion proteins
ATE199572T1 (de) 1995-11-21 2001-03-15 Univ Yale Unimolekulare segmentamplifikation und bestimmung
CU22559A1 (es) 1996-01-17 1999-05-03 Ct Ingenieria Genetica Biotech Sistema de expresión de antígenos heterologos en e. coli como proteínas de fusión
GB9726398D0 (en) 1997-12-12 1998-02-11 Isis Innovation Polypeptide and coding sequences
ES2333071T5 (es) 1998-01-14 2015-08-17 Novartis Vaccines And Diagnostics S.R.L. Antígenos de Neisseria meningitidis
GB9810276D0 (en) 1998-05-13 1998-07-15 Smithkline Beecham Biolog Novel compounds

Also Published As

Publication number Publication date
CA2314319A1 (en) 1999-06-24
HUP0100094A3 (en) 2003-08-28
US6607729B2 (en) 2003-08-19
KR20010033074A (ko) 2001-04-25
US20020102276A1 (en) 2002-08-01
US8067004B2 (en) 2011-11-29
CZ20002172A3 (cs) 2000-11-15
BR9814276A (pt) 2000-10-03
EP1045859A4 (en) 2001-08-22
US6197312B1 (en) 2001-03-06
CZ299646B6 (cs) 2008-10-01
US20050058660A1 (en) 2005-03-17
CN1284965A (zh) 2001-02-21
PL341160A1 (en) 2001-03-26
NO20002990L (no) 2000-08-08
IL136684A0 (en) 2001-06-14
PL205984B1 (pl) 2010-06-30
JP4356961B2 (ja) 2009-11-04
WO1999031132A1 (en) 1999-06-24
NO20002990D0 (no) 2000-06-09
EP2354230A1 (en) 2011-08-10
IL199175A (en) 2013-07-31
EP1045859A1 (en) 2000-10-25
US20130085262A1 (en) 2013-04-04
AU1649599A (en) 1999-07-05
US20120123093A1 (en) 2012-05-17
NZ505374A (en) 2002-03-01
GB9726398D0 (en) 1998-02-11
CA2314319C (en) 2013-08-13
US20100331537A1 (en) 2010-12-30
JP2009045071A (ja) 2009-03-05
HUP0100094A1 (hu) 2001-05-28
JP4651703B2 (ja) 2011-03-16
JP2002508394A (ja) 2002-03-19
US8034358B2 (en) 2011-10-11
CN101684148A (zh) 2010-03-31
US20090270591A1 (en) 2009-10-29
KR100571533B1 (ko) 2006-04-14
AU747742B2 (en) 2002-05-23
US6495345B1 (en) 2002-12-17

Similar Documents

Publication Publication Date Title
TR200001709T2 (tr) Yeni neisseria meningitids yüzey proteini
ATE352559T1 (de) Verfahren zur verminderung der immunogenität von proteinen
BR9910089A (pt) Composições e antìgenos de neisseria meningitidis
DE69838986D1 (de) Polypeptide, deren herstellung und verwendung
HUP9904023A2 (hu) Leptin antagonisták alkalmazása inzulin rezisztencia kezelésére II. típusú cukorbajban
ATE183514T1 (de) Peptide des menschlichen proteins p53 zum gebrauch in menschlichen-zytotoxischen-t-zell- antwort-induzierenden kompositionen sowie menschliche p53-protein-spezifische t-lymphocyten
DE69840195D1 (de) Verfahren und zusammensetzungen zur behinderung der vervielfältigung von hiv-1
FR2755608B1 (fr) Composition cosmetique comprenant un polymere anionique ou non ionique et une silicone carboxylique
ATE418563T1 (de) Nik proteine, nukleinsäure sowie verfahren
PT750672E (pt) Sequencias de adn para metaloproteases matriciais, sua preparacao e utilizacao.
SE8902532L (sv) Bestaemning av plasmaproteiner
FR2766193B1 (fr) Polypeptide chimerique comprenant le fragment b de la toxine shiga et des peptides d'interet therapeutique
EE200100472A (et) Polüpeptiid, antikehad, lahustuv polüpeptiid, polü- või oligonukleotiid ja meetod diferentsiaalseltekspresseerunud DNA järjestuste spetsiifiliseks identifitseerimiseks
ZA87141B (en) Dna sequences coding for proteins having the biological activity of husi-type i inhibitors,biotechnological methods for the preparation of said proteins and pharmaceutical compositions containing said proteins
ATE305037T1 (de) Peptide, die fähig sind die sh3-domäne des gap- proteins zu binden, ihre kodierende dns, ihre zubereitung und verwendung
TR200000416T2 (tr) Neisseria loctoferrin bağlayıcı protein.
ATE405649T1 (de) Hemmstoff zur diagnose und behandlung von haemophilia a patienten
DE59410423D1 (de) Serin-threonin-kinase enthaltendes mittel zur tumortherapie und tumordiagnose
EE200000478A (et) Peptiid, seda kodeeriv geen, diagnostiline reagent ja diagnostiline reaktiivikomplekt ning vaktsiinkasutamiseks riketsioosi ravis
TR199700842T1 (tr) Insan DNase I Varyantlari.
ATE313628T1 (de) Klonierung und expression von haemophilus somnus transferrin-bindenden proteinen
DE69628659D1 (de) Verfahren zur bestimmung von blutgerinnungsfaktoren viii und ix
FI973762A0 (fi) Ny gen
HUP9901346A2 (hu) Deltap62 polipeptid és variánsai, ezeket kódoló nukleinsav-szekvenciák és felhasználásuk
ATE530651T1 (de) Leishmania antigene für verwendung in der therapie und diagnose von leishmaniose