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TR200000928T2 - Yeni kombinasyon. - Google Patents

Yeni kombinasyon.

Info

Publication number
TR200000928T2
TR200000928T2 TR2000/00928T TR200000928T TR200000928T2 TR 200000928 T2 TR200000928 T2 TR 200000928T2 TR 2000/00928 T TR2000/00928 T TR 2000/00928T TR 200000928 T TR200000928 T TR 200000928T TR 200000928 T2 TR200000928 T2 TR 200000928T2
Authority
TR
Turkey
Prior art keywords
new combination
inhibitor
inflammatory
cyclooxygenase
administration
Prior art date
Application number
TR2000/00928T
Other languages
English (en)
Inventor
Hamley Peter
Tinker Alan
Original Assignee
Astrazeneca Uk Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Uk Limited filed Critical Astrazeneca Uk Limited
Publication of TR200000928T2 publication Critical patent/TR200000928T2/tr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Rheumatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

Abstract

Bulus, uyarilmis nitrik oksit sintazinin bir önleyicisi ile siklooksigenaz-2'nin bir önleyicisinin iltihap ve iltihabik bozukluklarin tedavisi için birlikte uygulanmasiyla ilgilidir.
TR2000/00928T 1997-10-10 1998-10-05 Yeni kombinasyon. TR200000928T2 (tr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE9703693A SE9703693D0 (sv) 1997-10-10 1997-10-10 Novel combination

Publications (1)

Publication Number Publication Date
TR200000928T2 true TR200000928T2 (tr) 2000-11-21

Family

ID=20408563

Family Applications (1)

Application Number Title Priority Date Filing Date
TR2000/00928T TR200000928T2 (tr) 1997-10-10 1998-10-05 Yeni kombinasyon.

Country Status (20)

Country Link
US (1) US6046191A (tr)
EP (1) EP1027052A1 (tr)
JP (1) JP2001519391A (tr)
KR (1) KR20010031017A (tr)
CN (1) CN1281362A (tr)
AU (1) AU9469398A (tr)
BR (1) BR9812753A (tr)
CA (1) CA2305141A1 (tr)
CZ (1) CZ20001272A3 (tr)
EE (1) EE200000192A (tr)
HU (1) HUP0003874A2 (tr)
IL (1) IL135248A0 (tr)
IS (1) IS5430A (tr)
MX (1) MXPA00003445A (tr)
NO (1) NO20001830L (tr)
PL (1) PL339769A1 (tr)
SE (1) SE9703693D0 (tr)
SK (1) SK4282000A3 (tr)
TR (1) TR200000928T2 (tr)
WO (1) WO1999018960A1 (tr)

Families Citing this family (48)

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SE9701304D0 (sv) * 1997-04-09 1997-04-09 Astra Pharma Prod Compounds
CN1323211A (zh) * 1998-08-11 2001-11-21 辉瑞产品公司 Nos抑制剂的新药学用途
EP1175214B1 (en) 1999-12-08 2004-11-24 Pharmacia Corporation Cyclooxygenase-2 inhibitor compositions having rapid onset of therapeutic effect
IL150368A0 (en) * 1999-12-23 2002-12-01 Nitromed Inc Nitrosated and nitrosylated cyclooxygenase-2-inhibitors, compositions and methods of use
GB0004153D0 (en) * 2000-02-23 2000-04-12 Astrazeneca Uk Ltd Novel use
US6800297B2 (en) * 2000-06-15 2004-10-05 Acusphere, Inc. Porous COX-2 inhibitor matrices and methods of manufacture thereof
US6589557B2 (en) * 2000-06-15 2003-07-08 Acusphere, Inc. Porous celecoxib matrices and methods of manufacture thereof
US20020035107A1 (en) 2000-06-20 2002-03-21 Stefan Henke Highly concentrated stable meloxicam solutions
IN191090B (tr) * 2000-08-29 2003-09-20 Ranbanx Lab Ltd
WO2002017896A2 (en) * 2000-08-29 2002-03-07 Peter Van Patten Combination for the treatment of migraine comprising a cyclooxygenase-2 inhibitor and acetylsalicylic acid
US7012098B2 (en) * 2001-03-23 2006-03-14 Pharmacia Corporation Inhibitors of inducible nitric oxide synthase for chemoprevention and treatment of cancers
US20030035795A1 (en) * 2001-04-13 2003-02-20 Gardell Stephen J. Methods for treating or reducing the risk of pain and inflammatory disorders by administering inhibitors of activated thrombin activatable fibrinolysis inhibitor
US20020187187A1 (en) * 2001-04-21 2002-12-12 Toshimitsu Ohki Fast disintegrating meloxicam tablet
AR035700A1 (es) * 2001-05-08 2004-06-23 Astrazeneca Ab Derivados de arilheteroalquilamina, composicion farmaceutica, usos de estos derivados para la fabricacion de medicamentos, metodos de tratamiento, y proceso para la preparacion de estos derivados
US20030114418A1 (en) * 2001-08-14 2003-06-19 Pharmacia Corporation Method for the treatment and prevention of pain and inflammation with glucosamine and a cyclooxygenase-2 selective inhibitor and compositions therefor
AR038957A1 (es) 2001-08-15 2005-02-02 Pharmacia Corp Terapia de combinacion para el tratamiento del cancer
EP1448209A2 (en) * 2001-10-23 2004-08-25 Ranbaxy Laboratories, Ltd. A process for the preparation of pharmaceutical compositions for topical delivery of cyclooxygenase-2 enzyme inhibitors
JP2005509002A (ja) * 2001-11-13 2005-04-07 ファルマシア コーポレイション スルホンアミドプロドラックの経口剤形
DE10161077A1 (de) 2001-12-12 2003-06-18 Boehringer Ingelheim Vetmed Hochkonzentrierte stabile Meloxicamlösungen zur nadellosen Injektion
BR0307772A (pt) * 2002-02-19 2004-12-07 Pharmacia Corp Uso de inibidores da ciclooxigenase e de agentes antimuscarìnicos para o tratamento da incontinência
CA2487414A1 (en) * 2002-06-11 2003-12-18 Nitromed, Inc. Nitrosated and/or nitrosylated cyclooxygenase-2 selective inhibitors, compositions and methods of use
JP2005538110A (ja) * 2002-07-29 2005-12-15 ニトロメッド インコーポレーティッド シクロオキシゲナーゼ−２選択的阻害剤、組成物、および使用方法
US8992980B2 (en) * 2002-10-25 2015-03-31 Boehringer Ingelheim Vetmedica Gmbh Water-soluble meloxicam granules
PL2266585T3 (pl) 2003-05-07 2013-10-31 Osteologix As Rozpuszczalne w wodzie sole stronktu do stosowania w leczeniu chorób chrząstki i/lub kości
EP2266584B1 (en) * 2003-05-07 2012-09-05 Osteologix A/S Composition with strontium and vitamin D for the prophylaxis and/or treatment of cartilage and/or bone conditions
EP1568369A1 (en) * 2004-02-23 2005-08-31 Boehringer Ingelheim Vetmedica Gmbh Use of meloxicam for the treatment of respiratory diseases in pigs
DE102004021281A1 (de) * 2004-04-29 2005-11-24 Boehringer Ingelheim Vetmedica Gmbh Verwendung von Meloxicam-Formulierungen in der Veterinärmedizin
EP1758652A2 (en) * 2004-06-17 2007-03-07 Osteologix A/S Improving pain treatment with strontium combinations
DE102004030409A1 (de) * 2004-06-23 2006-01-26 Boehringer Ingelheim Vetmedica Gmbh Neue Verwendung von Meloxicam in der Veterinärmedizin
NZ567627A (en) * 2005-09-30 2011-08-26 Boehringer Ingelheim Vetmed Granulation process for making a divisible tablet containing meloxicam
EP1942105B8 (en) 2005-10-25 2014-08-13 Shionogi&Co., Ltd. Aminodihydrothiazine derivative
JP2007275193A (ja) * 2006-04-04 2007-10-25 Fujifilm Corp 光プローブおよび光断層画像化装置
EP2052310A2 (en) * 2006-08-04 2009-04-29 UCL Business PLC Computer devices and accessories
GB0712287D0 (en) * 2007-06-22 2007-08-01 Ucl Business Plc Antimicrobial Conjugates
WO2008091530A2 (en) * 2007-01-19 2008-07-31 Mallinckrodt Inc. Diagnostic and therapeutic cyclooxygenase-2 binding ligands
WO2008133273A1 (ja) 2007-04-24 2008-11-06 Shionogi & Co., Ltd. アルツハイマー症治療用医薬組成物
EP2147914B1 (en) 2007-04-24 2014-06-04 Shionogi&Co., Ltd. Aminodihydrothiazine derivatives substituted with cyclic groups
DE102007049612A1 (de) * 2007-10-17 2009-06-10 Evonik Goldschmidt Gmbh Bioaktive Zusammensetzung für kosmetische Anwendungen
CN102119161B (zh) 2008-06-13 2015-07-08 盐野义制药株式会社 具有β分泌酶抑制作用的含硫杂环衍生物
JPWO2010047372A1 (ja) 2008-10-22 2012-03-22 塩野義製薬株式会社 Ｂａｃｅ１阻害活性を有する２−アミノピリミジン−４−オンおよび２−アミノピリジン誘導体
DK4378443T3 (da) * 2009-10-12 2025-08-18 Boehringer Ingelheim Vetmedica Gmbh Beholdere til sammensætninger, der omfatter meloxicam
MX2012006491A (es) 2009-12-11 2012-07-03 Shionogi & Co Derivados de oxazina.
SG183846A1 (en) 2010-03-03 2012-10-30 Boehringer Ingelheim Vetmed Use of meloxicam for the long-term treatment of musculoskeletal disorders in cats
US9795568B2 (en) 2010-05-05 2017-10-24 Boehringer Ingelheim Vetmedica Gmbh Low concentration meloxicam tablets
JP5766198B2 (ja) 2010-10-29 2015-08-19 塩野義製薬株式会社 縮合アミノジヒドロピリミジン誘導体
JP5816630B2 (ja) 2010-10-29 2015-11-18 塩野義製薬株式会社 ナフチリジン誘導体
WO2012147763A1 (ja) 2011-04-26 2012-11-01 塩野義製薬株式会社 オキサジン誘導体およびそれを含有するｂａｃｅ１阻害剤
US9540359B2 (en) 2012-10-24 2017-01-10 Shionogi & Co., Ltd. Dihydrooxazine or oxazepine derivatives having BACE1 inhibitory activity

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996041645A1 (en) * 1995-06-12 1996-12-27 G.D. Searle & Co. Combination of a cyclooxygenase-2 inhibitor and a leukotriene b4 receptor antagonist for the treatment of inflammations
AU6111796A (en) * 1995-06-12 1997-01-09 G.D. Searle & Co. Compositions comprising a cyclooxygenase-2 inhibitor and a 5 -lipoxygenase inhibitor
JP2001506574A (ja) * 1996-02-13 2001-05-22 ジー．ディー．サール アンド カンパニー シクロオキシゲナーゼ―２阻害剤およびロイコトリエンａ４ヒドロラーゼ阻害剤を含有する免疫抑制効果をもつ配合物

Also Published As

Publication number Publication date
EP1027052A1 (en) 2000-08-16
EE200000192A (et) 2001-04-16
HUP0003874A2 (hu) 2001-05-28
MXPA00003445A (es) 2001-06-01
NO20001830D0 (no) 2000-04-07
PL339769A1 (en) 2001-01-02
US6046191A (en) 2000-04-04
BR9812753A (pt) 2000-08-29
CA2305141A1 (en) 1999-04-22
JP2001519391A (ja) 2001-10-23
AU9469398A (en) 1999-05-03
NO20001830L (no) 2000-05-10
IS5430A (is) 2000-04-06
SK4282000A3 (en) 2001-01-18
IL135248A0 (en) 2001-05-20
WO1999018960A1 (en) 1999-04-22
CN1281362A (zh) 2001-01-24
KR20010031017A (ko) 2001-04-16
CZ20001272A3 (cs) 2000-09-13
SE9703693D0 (sv) 1997-10-10

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