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TR200000033T2 - Oksimorfon, oksikodon ve türevlerinin hazırlanması - Google Patents

Oksimorfon, oksikodon ve türevlerinin hazırlanması

Info

Publication number
TR200000033T2
TR200000033T2 TR2000/00033T TR200000033T TR200000033T2 TR 200000033 T2 TR200000033 T2 TR 200000033T2 TR 2000/00033 T TR2000/00033 T TR 2000/00033T TR 200000033 T TR200000033 T TR 200000033T TR 200000033 T2 TR200000033 T2 TR 200000033T2
Authority
TR
Turkey
Prior art keywords
derivatives
oxymorphone
oxycodone
preparation
noroxymorphone
Prior art date
Application number
TR2000/00033T
Other languages
English (en)
Inventor
Huang Bao-Shan
Christodoulou Aris
Lu Yansong
Ji Ben-Yi
Original Assignee
Penick Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25401603&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=TR200000033(T2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Penick Corporation filed Critical Penick Corporation
Publication of TR200000033T2 publication Critical patent/TR200000033T2/tr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D489/00—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
    • C07D489/06—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: with a hetero atom directly attached in position 14
    • C07D489/08—Oxygen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D489/00—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
    • C07D489/02—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: with oxygen atoms attached in positions 3 and 6, e.g. morphine, morphinone

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)

Abstract

Bulus, morfinden sentezlenebilecek olan normorfinon ve türevlerinin, mukabil 14-hidroksinormorfinon ve aralarinda, oksikodon, oksimorfon, noroksimorfon ve naltrekson olan türevlerine dönüstürülmesi için islemler temin etmektedir. Noroksimorfon, önemli narkotik analijesikler ve antagonistlerinin üretimi için bir anahtar ara maddedir. Bulus, ayni zamanda, bazi yeni ara maddeleri de temin etmektedir.
TR2000/00033T 1997-07-11 1998-07-10 Oksimorfon, oksikodon ve türevlerinin hazırlanması TR200000033T2 (tr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/893,464 US5869669A (en) 1996-07-26 1997-07-11 Preparation of 14-hydroxynormorphinones from normorphinone dienol acylates

Publications (1)

Publication Number Publication Date
TR200000033T2 true TR200000033T2 (tr) 2000-12-21

Family

ID=25401603

Family Applications (1)

Application Number Title Priority Date Filing Date
TR2000/00033T TR200000033T2 (tr) 1997-07-11 1998-07-10 Oksimorfon, oksikodon ve türevlerinin hazırlanması

Country Status (19)

Country Link
US (7) US5869669A (tr)
EP (1) EP1000065B1 (tr)
JP (1) JP2001518444A (tr)
KR (1) KR100363486B1 (tr)
CN (1) CN1152880C (tr)
AT (1) ATE291023T1 (tr)
AU (1) AU740822B2 (tr)
CA (1) CA2296035C (tr)
DE (1) DE69829379D1 (tr)
HU (1) HUP0003918A3 (tr)
IL (1) IL133792A0 (tr)
IN (1) IN1998KO01500A (tr)
NO (1) NO20000111L (tr)
RU (1) RU2183636C2 (tr)
SK (1) SK102000A3 (tr)
TR (1) TR200000033T2 (tr)
TW (1) TW505648B (tr)
WO (1) WO1999002529A1 (tr)
ZA (1) ZA986144B (tr)

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Also Published As

Publication number Publication date
EP1000065A1 (en) 2000-05-17
US5948788A (en) 1999-09-07
HUP0003918A2 (hu) 2001-07-30
IL133792A0 (en) 2001-04-30
TW505648B (en) 2002-10-11
CA2296035C (en) 2004-04-13
KR20010021693A (ko) 2001-03-15
DE69829379D1 (de) 2005-04-21
US6008354A (en) 1999-12-28
ZA986144B (en) 1999-05-19
SK102000A3 (en) 2000-07-11
CA2296035A1 (en) 1999-01-21
IN1998KO01500A (tr) 2005-03-11
US5952495A (en) 1999-09-14
RU2183636C2 (ru) 2002-06-20
US5922876A (en) 1999-07-13
CN1152880C (zh) 2004-06-09
NO20000111L (no) 2000-02-25
ATE291023T1 (de) 2005-04-15
AU8379198A (en) 1999-02-08
KR100363486B1 (ko) 2002-12-16
HK1028025A1 (en) 2001-02-02
EP1000065B1 (en) 2005-03-16
EP1000065A4 (en) 2001-09-12
NO20000111D0 (no) 2000-01-10
JP2001518444A (ja) 2001-10-16
US6008355A (en) 1999-12-28
AU740822B2 (en) 2001-11-15
US5869669A (en) 1999-02-09
WO1999002529A1 (en) 1999-01-21
US6013796A (en) 2000-01-11
HUP0003918A3 (en) 2003-04-28
CN1272845A (zh) 2000-11-08

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