[go: up one dir, main page]

TR199900140T2 - Pharmaceutical composition comprising a 5HT2C antagonist and a D2 antagonist. - Google Patents

Pharmaceutical composition comprising a 5HT2C antagonist and a D2 antagonist.

Info

Publication number
TR199900140T2
TR199900140T2 TR1999/00140T TR9900140T TR199900140T2 TR 199900140 T2 TR199900140 T2 TR 199900140T2 TR 1999/00140 T TR1999/00140 T TR 1999/00140T TR 9900140 T TR9900140 T TR 9900140T TR 199900140 T2 TR199900140 T2 TR 199900140T2
Authority
TR
Turkey
Prior art keywords
antagonist
5ht2c
pharmaceutical composition
compounds
activity
Prior art date
Application number
TR1999/00140T
Other languages
Turkish (tr)
Inventor
Thomas Paul Blackburn Dr.
Original Assignee
Smithkline Beecham P.L.C.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham P.L.C. filed Critical Smithkline Beecham P.L.C.
Publication of TR199900140T2 publication Critical patent/TR199900140T2/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Neurosurgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Psychiatry (AREA)
  • Neurology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Bulus 5HT2C ve D2 antagonist faaliyetine sahip bilesiklerin kombinasyonlari, iki reseptörün faaliyetine sahip bilesikler, bunlari ihtiva eden farmasötik bilesimler ve bunlarin sizofrenin tedavisinde kullanimi ile ilgilidir.The invention relates to combinations of 5HT2C and D2 antagonist activity compounds, compounds with activity of two receptors, pharmaceutical compositions containing them and their use in the treatment of schizophrenia.

TR1999/00140T 1996-07-26 1997-07-22 Pharmaceutical composition comprising a 5HT2C antagonist and a D2 antagonist. TR199900140T2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9615767.2A GB9615767D0 (en) 1996-07-26 1996-07-26 Novel treatment

Publications (1)

Publication Number Publication Date
TR199900140T2 true TR199900140T2 (en) 1999-03-22

Family

ID=10797573

Family Applications (1)

Application Number Title Priority Date Filing Date
TR1999/00140T TR199900140T2 (en) 1996-07-26 1997-07-22 Pharmaceutical composition comprising a 5HT2C antagonist and a D2 antagonist.

Country Status (19)

Country Link
EP (1) EP0936924A2 (en)
JP (1) JP2000516924A (en)
KR (1) KR20000029564A (en)
CN (1) CN1230894A (en)
AR (1) AR008083A1 (en)
AU (1) AU725817B2 (en)
BR (1) BR9710568A (en)
CA (1) CA2261813A1 (en)
CO (1) CO5031292A1 (en)
CZ (1) CZ23799A3 (en)
GB (1) GB9615767D0 (en)
HU (1) HUP9903619A3 (en)
IL (1) IL128219A0 (en)
NO (1) NO990322L (en)
NZ (1) NZ333813A (en)
PL (1) PL331426A1 (en)
TR (1) TR199900140T2 (en)
WO (1) WO1998004289A2 (en)
ZA (1) ZA976593B (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9612883D0 (en) * 1996-06-20 1996-08-21 Smithkline Beecham Plc Novel compounds
EP1133299A1 (en) 1998-11-23 2001-09-19 Sepracor Inc. 2-hydroxymethylolanzapine compositions and methods
EP1135136B1 (en) * 1998-11-23 2003-11-05 Sepracor Inc. Pharmaceutical compositions containing olanzapine-n-oxide
WO2000030650A1 (en) 1998-11-23 2000-06-02 Sepracor Inc. Desmethylolanzapine compositions and methods
WO2000054764A2 (en) * 1999-03-18 2000-09-21 Children's Hospital Research Foundation A method of treating bulimia nervosa and related eating disorders by administration of atypical antipsychotic medications
AU4598400A (en) * 1999-05-19 2000-12-12 Astrazeneca Ab Method of treatment
WO2005013969A1 (en) * 2003-07-15 2005-02-17 Janssen Pharmaceutica N.V. Antipsychotic agent with socializing properties

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9500998D0 (en) * 1995-03-19 1995-03-19 Haakan Wilhelm Wikstroem New sulfone ester analogues of iso-clozapine and related structures: atypical neuroleptics

Also Published As

Publication number Publication date
HUP9903619A2 (en) 2000-10-28
CZ23799A3 (en) 1999-06-16
BR9710568A (en) 1999-08-17
KR20000029564A (en) 2000-05-25
AR008083A1 (en) 1999-12-09
CO5031292A1 (en) 2001-04-27
CN1230894A (en) 1999-10-06
EP0936924A2 (en) 1999-08-25
ZA976593B (en) 1999-01-25
GB9615767D0 (en) 1996-09-04
NO990322L (en) 1999-03-24
AU725817B2 (en) 2000-10-19
AU4297297A (en) 1998-02-20
WO1998004289A2 (en) 1998-02-05
IL128219A0 (en) 1999-11-30
WO1998004289A3 (en) 1998-03-19
NZ333813A (en) 2000-07-28
PL331426A1 (en) 1999-07-19
NO990322D0 (en) 1999-01-25
HUP9903619A3 (en) 2001-03-28
JP2000516924A (en) 2000-12-19
CA2261813A1 (en) 1998-02-05

Similar Documents

Publication Publication Date Title
TR199802284T2 (en) Tetrahydroisoquinoline derivatives as modulators of dopamine D3 receptors.
MX9705296A (en) Novel compounds.
TR199902033T2 (en) Sulfonylura-glitazone synergistic combinations for diabetes.
TR200001218T2 (en) Substituted carboxamidothiazoles, their manufacture and pharmaceutical compositions containing them.
TR199802423T2 (en) Concentrated antibody composition.
YU83600A (en) Adenosine a3 receptor modulators
ES2184800T3 (en) USE OF ANTI-VEGF AGENTS IN THE TREATMENT OF ENDOMETRIOSIS.
UA41316C2 (en) tricyclic derivatives of pyrrole and pharmaceutical agent
PT1093819E (en) COMPOUNDS AND COMPOSITIONS FOR THE SUPPLY OF ACTIVE AGENTS
ATE332918T1 (en) NEOGLYCOPROTEINS
DE69501591D1 (en) LACTOBACILLA STRAINS OF HUMAN ORIGIN, THEIR COMPOSITION AND THEIR USE
TR200100299T2 (en) Therapeutic biaryl derivatives.
FI972086A7 (en) Novel amino acid derivatives with improved multidrug resistance activity
PT839143E (en) TETRALINE COMPOUNDS WITH MDR ACTIVITY
TR199902383T2 (en) New pyrimidine derivatives and the process for their preparation.
ATE231872T1 (en) THIAZOLOPYRIMIDE DERIVATIVES
BR9909486A (en) Calcilic compounds
ATE204177T1 (en) USE OF SUBSTANCE P ANTAGONIST IN PHARMACEUTICAL COMPOSITION
TR199900140T2 (en) Pharmaceutical composition comprising a 5HT2C antagonist and a D2 antagonist.
PT101444A (en) SYNERGIZING ASSOCIATION WITH ANTAGONIST EFFECT OF RECEPTORS NK1 AND NK2, USE OF ANTAGONIST ACTIVITY OF NK1 AND NK2 RECEPTORS IN THEIR PREPARATION AND PHARMACEUTICAL COMPOSITION CONTAINING THE REFERENCE ASSOCIATION
TR199900872T1 (en) Bi-aromatic compounds linked with a heteroethynylene radical and pharmaceutical and cosmetic compositions containing them.
CL2002001701A1 (en) Use of at least one compound selected from melatonin, melatoninergic agents, melatonin agonists and antagonists, in an amount of 0.0025-50 mg, to prepare a useful medicine for the treatment and improvement of the restorative quality of sleep.
PL339073A1 (en) Derivatives of benzoxazine and benzothiazine and their application in therapeutic agents
TR200103090T2 (en) Integrine receptor antagonists
ATE332728T1 (en) PHOTOSENSITIVE SUNSCREEN