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TR199800904T2 - Production of new quinoxalindione derivatives and their use in medicines - Google Patents

Production of new quinoxalindione derivatives and their use in medicines

Info

Publication number
TR199800904T2
TR199800904T2 TR1998/00904T TR9800904T TR199800904T2 TR 199800904 T2 TR199800904 T2 TR 199800904T2 TR 1998/00904 T TR1998/00904 T TR 1998/00904T TR 9800904 T TR9800904 T TR 9800904T TR 199800904 T2 TR199800904 T2 TR 199800904T2
Authority
TR
Turkey
Prior art keywords
new
production
medicines
derivatives
quinoxalindione
Prior art date
Application number
TR1998/00904T
Other languages
Turkish (tr)
Inventor
Huth Andreas
Kruger Martin
Ottow Eckhar
Seidelmann Dieter
Neuhaus Roland
Schneider Herbert
Turski Lechoslaw
Original Assignee
Schering Aktiengesellschaft
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Aktiengesellschaft filed Critical Schering Aktiengesellschaft
Publication of TR199800904T2 publication Critical patent/TR199800904T2/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/36—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems
    • C07D241/38—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems with only hydrogen or carbon atoms directly attached to the ring nitrogen atoms
    • C07D241/40—Benzopyrazines
    • C07D241/44—Benzopyrazines with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/645—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having two nitrogen atoms as the only ring hetero atoms
    • C07F9/6509—Six-membered rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/645—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having two nitrogen atoms as the only ring hetero atoms
    • C07F9/6509—Six-membered rings
    • C07F9/650952—Six-membered rings having the nitrogen atoms in the positions 1 and 4
    • C07F9/650994—Six-membered rings having the nitrogen atoms in the positions 1 and 4 condensed with carbocyclic rings or carbocyclic ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Içinde R1, R5, R6 ve R7 'nin patentte tanimlanmis anlama sahip oldugu, formül (l) deki yeni kinoksalindiyon türevleri, bu türevlerin üretimi ve tip ilaçlarinda kullanimi açiklanmaktadir.The new quinoxalindion derivatives of formula (1) in which R1, R5, R6 and R7 have the meaning defined in the patent, the production of these derivatives and their use in type drugs are explained.

TR1998/00904T 1995-11-24 1996-11-15 Production of new quinoxalindione derivatives and their use in medicines TR199800904T2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19545251A DE19545251A1 (en) 1995-11-24 1995-11-24 New quinoxalinedione derivatives, their production and use in pharmaceuticals

Publications (1)

Publication Number Publication Date
TR199800904T2 true TR199800904T2 (en) 1998-08-21

Family

ID=7779176

Family Applications (1)

Application Number Title Priority Date Filing Date
TR1998/00904T TR199800904T2 (en) 1995-11-24 1996-11-15 Production of new quinoxalindione derivatives and their use in medicines

Country Status (20)

Country Link
EP (1) EP0876357A1 (en)
JP (1) JP2000500471A (en)
KR (1) KR19990071596A (en)
CN (1) CN1202891A (en)
AU (1) AU720083B2 (en)
CA (1) CA2238023A1 (en)
CZ (1) CZ160498A3 (en)
DE (1) DE19545251A1 (en)
EE (1) EE9800163A (en)
HU (1) HUP9902041A3 (en)
IL (1) IL124534A0 (en)
IS (1) IS4740A (en)
MX (1) MX9804068A (en)
NO (1) NO982349L (en)
NZ (1) NZ330492A (en)
PL (1) PL326844A1 (en)
SK (1) SK68298A3 (en)
TR (1) TR199800904T2 (en)
WO (1) WO1997019066A1 (en)
ZA (1) ZA969832B (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19737446A1 (en) * 1997-08-22 1999-02-25 Schering Ag Preparation of phosphonic acid derivatives
EP2338492A1 (en) 2009-12-24 2011-06-29 Universidad del Pais Vasco Methods and compositions for the treatment of alzheimer
CN106619953A (en) * 2016-10-31 2017-05-10 山东省海盟生化科技有限公司 External traditional Chinese medicine composition for skin diseases, method for preparing external traditional Chinese medicine composition and application thereof

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NO179551C (en) * 1987-11-10 1996-10-30 Novo Nordisk As Analogous Process for Preparing Therapeutically Effective Quinoxaline Compounds
DK69790D0 (en) * 1990-03-16 1990-03-16 Novo Nordisk As HETEROCYCLIC COMPOUNDS, THEIR PREPARATION OF USE
PT101004B (en) * 1991-10-26 1999-10-29 Schering Ag QUINOXALINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS THAT CONTAIN THEM
IL109397A0 (en) * 1993-04-28 1994-07-31 Schering Ag Quinoxalinedione derivatives, processes for the preparation thereof and pharmaceutical compositions containing the same
DE4439492A1 (en) * 1994-10-25 1996-05-02 Schering Ag New quinoxalinedione derivatives, their production and use in pharmaceuticals
DE4439493A1 (en) * 1994-10-25 1996-05-02 Schering Ag New quinoxalinedione derivatives, their production and use in pharmaceuticals
DE19519979A1 (en) * 1995-05-24 1996-11-28 Schering Ag New quinoxalinedione derivatives, their production and use in pharmaceuticals

Also Published As

Publication number Publication date
WO1997019066A1 (en) 1997-05-29
NZ330492A (en) 1999-10-28
IS4740A (en) 1998-05-13
PL326844A1 (en) 1998-10-26
JP2000500471A (en) 2000-01-18
CZ160498A3 (en) 1998-09-16
AU1867497A (en) 1997-06-11
CN1202891A (en) 1998-12-23
HUP9902041A2 (en) 2000-04-28
IL124534A0 (en) 1998-12-06
MX9804068A (en) 1998-09-30
AU720083B2 (en) 2000-05-25
ZA969832B (en) 1997-06-17
EE9800163A (en) 1998-12-15
SK68298A3 (en) 1998-12-02
DE19545251A1 (en) 1997-05-28
HUP9902041A3 (en) 2000-07-28
NO982349L (en) 1998-07-01
KR19990071596A (en) 1999-09-27
NO982349D0 (en) 1998-05-22
EP0876357A1 (en) 1998-11-11
CA2238023A1 (en) 1997-05-29

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