TNSN04054A1 - Formulations pharmaceutiques pour la liberation controlee de la 4-amino-6, 7-dimethoxy-2-(5-methanesulfonamido-1,2,3,4-tetrahydroisoquinol-2-yl)-5-(2-pyridyl)-quinazoline - Google Patents
Formulations pharmaceutiques pour la liberation controlee de la 4-amino-6, 7-dimethoxy-2-(5-methanesulfonamido-1,2,3,4-tetrahydroisoquinol-2-yl)-5-(2-pyridyl)-quinazolineInfo
- Publication number
- TNSN04054A1 TNSN04054A1 TNP2004000054A TNSN04054A TNSN04054A1 TN SN04054 A1 TNSN04054 A1 TN SN04054A1 TN P2004000054 A TNP2004000054 A TN P2004000054A TN SN04054 A TNSN04054 A TN SN04054A TN SN04054 A1 TNSN04054 A1 TN SN04054A1
- Authority
- TN
- Tunisia
- Prior art keywords
- tetrahydroisoquinol
- dimethoxy
- pyridyl
- amino
- methanesulfonamido
- Prior art date
Links
- 238000013270 controlled release Methods 0.000 title abstract 2
- OLYXPBZBZBVRGD-UHFFFAOYSA-N n-[2-(4-amino-6,7-dimethoxy-5-pyridin-2-ylquinazolin-2-yl)-3,4-dihydro-1h-isoquinolin-5-yl]methanesulfonamide Chemical compound COC=1C(OC)=CC2=NC(N3CC4=C(C(=CC=C4)NS(C)(=O)=O)CC3)=NC(N)=C2C=1C1=CC=CC=N1 OLYXPBZBZBVRGD-UHFFFAOYSA-N 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 239000000203 mixture Substances 0.000 abstract 3
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 abstract 2
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 abstract 2
- 238000009472 formulation Methods 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 239000002671 adjuvant Substances 0.000 abstract 1
- 239000003085 diluting agent Substances 0.000 abstract 1
- 239000012738 dissolution medium Substances 0.000 abstract 1
- 206010020718 hyperplasia Diseases 0.000 abstract 1
- 239000002609 medium Substances 0.000 abstract 1
- 230000000144 pharmacologic effect Effects 0.000 abstract 1
- 239000011780 sodium chloride Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B35/00—Reactions without formation or introduction of functional groups containing hetero atoms, involving a change in the type of bonding between two carbon atoms already directly linked
- C07B35/04—Dehydrogenation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Urology & Nephrology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
LA PRESENTE INVENTION PROPOSE UNE FORMULATION PHARMACEUTIQUE A LIBERATION CONTROLEE POUR ADMINISTRATION ORALE; COMPRENANT DE LA 4-AMINO-6;7- DIMETHOXY-2-(5-METHANE-SULFONAMIDO-1;2;3;4-TETRAHYDROISOQUINOL-2-YL)-5-(2-PYRIDYL)-QUINAZOLINE; OU UN DE SES SELS PHARMACEUTIQUEMENT ACCEPTABLES; ET UN ADJUVANT; DILUANT OU SUPPORT PHARMACEUTIQUEMENT ACCEPTABLE; LADITE FORMULATION ETANT CARACTERISEE EN CE QU'ELLE EST ADAPTEE A LIBERER AU MOINS 50% EN POIDS DE LA 4-AMINO-6;7-DIMETHOXY-2-(5-METHANESULFONAMIDO-1;2;3;4;-TETRAHYDROISOQUINOL-2-YL) –5-(2-PYRIDYL)-QUINAZOLINE; OU DE SON SEL PHARMACEUTIQUEMENT ACCEPTABLE; AU BOUT DE 6 HEURES DANS L'APPAREIL 1 DECRIT DANS LA PHARMACOPEE DES ETATS-UNIS D'AMERIQUE 24 (2000); PAGES 1941-1943; COMPRENANT DES RECIPIENTS D'UN LITRE; DES PANIERS A MAILLES N° 40 (OUVERTURES DE 0;4 MM); A UNE VITESSE DE ROTATION DE 100 TR/MIN; ET AVEC UN MILIEU DE DISSOLUTION CONSISTANT EN 900 ML D'ACIDE CHLORYDRIQUE 0;01 M CONTENANT 0;7% EN POIDS/VOLUME DE CHLORURE DE SODIUM A 37° C. LES FORMULATIONS CONFORMES A LA PRESENTE INVENTION CONVIENNENT AU TRAITEMENT DE L'HYPERPLASIE PROSTATIQUE BENIGNE (HPB).
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB1244/55A GB793192A (en) | 1955-01-14 | 1955-01-14 | Improvements in or relating to the oxidative treatment of organic substances |
| PCT/IB2002/004040 WO2003032956A1 (fr) | 2001-10-11 | 2002-09-30 | Formulations pharmaceutiques destinees a la liberation controlee de 4-amino-6,7-dimethoxy-2-(5-methanesulfonamido-1,2,3,4-tetrahydroisoquinol-2-yl)-5-(2-pyridyl) quinazoline |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TNSN04054A1 true TNSN04054A1 (fr) | 2006-06-01 |
Family
ID=6709033
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TNP2004000054A TNSN04054A1 (fr) | 1955-01-14 | 2004-04-07 | Formulations pharmaceutiques pour la liberation controlee de la 4-amino-6, 7-dimethoxy-2-(5-methanesulfonamido-1,2,3,4-tetrahydroisoquinol-2-yl)-5-(2-pyridyl)-quinazoline |
Country Status (2)
| Country | Link |
|---|---|
| GB (1) | GB793192A (fr) |
| TN (1) | TNSN04054A1 (fr) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1997019729A1 (fr) * | 1995-11-28 | 1997-06-05 | Ici Canada Inc. | Procede et appareil d'epuration d'acide residuel |
-
1955
- 1955-01-14 GB GB1244/55A patent/GB793192A/en not_active Expired
-
2004
- 2004-04-07 TN TNP2004000054A patent/TNSN04054A1/fr unknown
Also Published As
| Publication number | Publication date |
|---|---|
| GB793192A (en) | 1958-04-09 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| NO174916B (no) | Fremgangsmåte for fremstilling av et medikament for behandling av öyenbetennelser | |
| FR2439189A1 (fr) | Nouveaux derives de la 5h-2,3-benzodiazepine et procede pour la preparation de ces derives et compositions pharmaceutiques les contenant | |
| NO941918L (no) | Indolderivater | |
| BE899635A (fr) | Compositions pharmaceutiques. | |
| BE900660A (fr) | Composition therapeutique pour le traitement des sequelles d'intoxication. | |
| BE1002109A3 (fr) | Composition pharmaceutique a activite analgesique. | |
| TNSN96161A1 (fr) | Derives de la quinoleine et de quinazoline nouveaux procede pour leur preparation et formulations pharmaceutiques les contenant. | |
| KR920008026A (ko) | 이소퀴놀리논 유도체 또는 이의 무독성 산부가염 또는 이의 수화물, 이의 제조방법 및 이를 포함하는 약제 조성물 | |
| WO1982001821A1 (fr) | Composition pharmaceutiques antimycotiques synergiques et leur procede de preparation | |
| BG51341A3 (bg) | Метод за получаване на фармацевтичен състав | |
| KR890003382A (ko) | 항 비루스성 화합물 | |
| FR2438654A1 (fr) | Compose de 2-methyl-dihydropyridine, procedes pour son obtention et composition pharmaceutique contenant ce compose | |
| TNSN04054A1 (fr) | Formulations pharmaceutiques pour la liberation controlee de la 4-amino-6, 7-dimethoxy-2-(5-methanesulfonamido-1,2,3,4-tetrahydroisoquinol-2-yl)-5-(2-pyridyl)-quinazoline | |
| FR2500303A1 (fr) | Le chlorure de gallium, nouveau medicament anti-cancereux | |
| FR2685918B1 (fr) | Nouveaux derives de l'adenosine, leurs procedes de preparation, compositions pharmaceutiques les contenant. | |
| MA27075A1 (fr) | Formulations pharmaceutiques pour la liberation controlee de la 4-amino-6,7-dimethoxy-2-(5-methanesulfonamido-1,2,3,4-tetrahydroisoquinol-2-yl)-5-(2-pyridyl) - quinazoline | |
| Mulvaney et al. | Urinary phenazopyridine stones: a complication of therapy | |
| US3996356A (en) | Composition containing 5-sulfanilamido-3,4-dimethylisoxazole and a trimethoxybenzyl pyrimidine | |
| TNSN00015A1 (fr) | Nouveaux sels de morpholinobenzamide | |
| US3737552A (en) | Method of treating gonorrhea | |
| Earle et al. | Studies on the chemotherapy of the human malarias. X. The suppressive antimalarial effect of paludrine | |
| JP3061445B2 (ja) | 血管拡張剤 | |
| GB1313164A (en) | Blood plasma substitute | |
| KR860000070A (ko) | 종양 발육억제 조성물 | |
| EP0830144A1 (fr) | Compositions pulverulentes et solubles dans l'eau et leurs applications |