TNSN99152A1 - ANTIOXIDANT AND ANTIPROLIFERATIVE COMPOSITION COMPRISING A CARNITINE AND A CAROTENOID - Google Patents
ANTIOXIDANT AND ANTIPROLIFERATIVE COMPOSITION COMPRISING A CARNITINE AND A CAROTENOIDInfo
- Publication number
- TNSN99152A1 TNSN99152A1 TNTNSN99152A TNSN99152A TNSN99152A1 TN SN99152 A1 TNSN99152 A1 TN SN99152A1 TN TNSN99152 A TNTNSN99152 A TN TNSN99152A TN SN99152 A TNSN99152 A TN SN99152A TN SN99152 A1 TNSN99152 A1 TN SN99152A1
- Authority
- TN
- Tunisia
- Prior art keywords
- carotenoid
- carnitine
- composition
- antioxidant
- dietetic
- Prior art date
Links
- 235000021466 carotenoid Nutrition 0.000 title abstract 2
- 150000001747 carotenoids Chemical class 0.000 title abstract 2
- PHIQHXFUZVPYII-ZCFIWIBFSA-O (R)-carnitinium Chemical compound C[N+](C)(C)C[C@H](O)CC(O)=O PHIQHXFUZVPYII-ZCFIWIBFSA-O 0.000 title 1
- 230000001028 anti-proliverative effect Effects 0.000 title 1
- 239000003963 antioxidant agent Substances 0.000 title 1
- 230000003078 antioxidant effect Effects 0.000 title 1
- 229960004203 carnitine Drugs 0.000 title 1
- 235000005911 diet Nutrition 0.000 abstract 2
- 230000000378 dietary effect Effects 0.000 abstract 2
- 201000010099 disease Diseases 0.000 abstract 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
- UPYKUZBSLRQECL-UKMVMLAPSA-N Lycopene Natural products CC(=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C1C(=C)CCCC1(C)C)C=CC=C(/C)C=CC2C(=C)CCCC2(C)C UPYKUZBSLRQECL-UKMVMLAPSA-N 0.000 abstract 1
- JEVVKJMRZMXFBT-XWDZUXABSA-N Lycophyll Natural products OC/C(=C/CC/C(=C\C=C\C(=C/C=C/C(=C\C=C\C=C(/C=C/C=C(\C=C\C=C(/CC/C=C(/CO)\C)\C)/C)\C)/C)\C)/C)/C JEVVKJMRZMXFBT-XWDZUXABSA-N 0.000 abstract 1
- UFAHZIUFPNSHSL-MRVPVSSYSA-N O-propanoyl-L-carnitine Chemical compound CCC(=O)O[C@H](CC([O-])=O)C[N+](C)(C)C UFAHZIUFPNSHSL-MRVPVSSYSA-N 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 230000002248 lipoperoxidative effect Effects 0.000 abstract 1
- OAIJSZIZWZSQBC-GYZMGTAESA-N lycopene Chemical compound CC(C)=CCC\C(C)=C\C=C\C(\C)=C\C=C\C(\C)=C\C=C\C=C(/C)\C=C\C=C(/C)\C=C\C=C(/C)CCC=C(C)C OAIJSZIZWZSQBC-GYZMGTAESA-N 0.000 abstract 1
- 229960004999 lycopene Drugs 0.000 abstract 1
- 235000012661 lycopene Nutrition 0.000 abstract 1
- 239000001751 lycopene Substances 0.000 abstract 1
- 229940126601 medicinal product Drugs 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 239000013589 supplement Substances 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
- ZCIHMQAPACOQHT-ZGMPDRQDSA-N trans-isorenieratene Natural products CC(=C/C=C/C=C(C)/C=C/C=C(C)/C=C/c1c(C)ccc(C)c1C)C=CC=C(/C)C=Cc2c(C)ccc(C)c2C ZCIHMQAPACOQHT-ZGMPDRQDSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/205—Amine addition salts of organic acids; Inner quaternary ammonium salts, e.g. betaine, carnitine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/81—Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/02—Antidotes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/06—Free radical scavengers or antioxidants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Toxicology (AREA)
- Epidemiology (AREA)
- Urology & Nephrology (AREA)
- Heart & Thoracic Surgery (AREA)
- Microbiology (AREA)
- Ophthalmology & Optometry (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Dermatology (AREA)
- Vascular Medicine (AREA)
- Alternative & Traditional Medicine (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Medical Informatics (AREA)
- Cardiology (AREA)
- Mycology (AREA)
- Biochemistry (AREA)
- Emergency Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Plant Substances (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
UNE COMPOSITION COMPRENANT COMME INGREDIENTS ACTIFS CARACTERISTIQUES LE PROPIONYL L-CARNITINE ET AU MOINS UN CAROTENOIDE SPECIFIQUEMENT LE LYCOPENE EXTRAIT A PARTIR DE TOMATES ET QUI EST DESTINES A LA PREVENTION ET/OU AU TRAITEMENT THERAPEUTIQUE DES DIFFERENTES ALTERATIONS ET ETATS PATHOLOGIQUES INDUITS PAR LA PRESENCE DE RADICAUX A L'ETAT LIBRE, ET PAR LE PHENOMENE DE LIPOPEROXYDATION. CETTE COMPOSITION PEUT AVOIR LA FORME D'UN SUPPLEMENT DIETETIQUE, D'UN SUPPORT DIETETIQUE OU D'UN MEDICAMENT EFFECTIFA COMPOSITION COMPRISING AS CHARACTERISTIC ACTIVE INGREDIENTS PROPIONYL L-CARNITINE AND AT LEAST ONE CAROTENOID SPECIFICALLY LYCOPENE EXTRACTED FROM TOMATOES AND WHICH ARE INTENDED FOR THE PREVENTION AND / OR THERAPEUTIC TREATMENT OF DIFFERENT DISEASES AND DISEASES IN THE FREE STATE, AND BY THE LIPOPEROXIDATION PHENOMENON. THIS COMPOSITION MAY HAVE THE FORM OF A DIETETIC SUPPLEMENT, A DIETETIC SUPPORT OR AN EFFECTIVE MEDICINAL PRODUCT
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT1998RM000516A IT1302125B1 (en) | 1998-08-03 | 1998-08-03 | COMPOSITION WITH ANTIOXIDANT AND ANTIPROLIFERATIVE ACTIVITY INCLUDING A CARNITINE AND A CAROTENOID |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TNSN99152A1 true TNSN99152A1 (en) | 2005-11-10 |
Family
ID=11406082
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TNTNSN99152A TNSN99152A1 (en) | 1998-08-03 | 1999-07-30 | ANTIOXIDANT AND ANTIPROLIFERATIVE COMPOSITION COMPRISING A CARNITINE AND A CAROTENOID |
Country Status (21)
| Country | Link |
|---|---|
| EP (1) | EP1102584A2 (en) |
| JP (1) | JP2002522382A (en) |
| KR (1) | KR20010072146A (en) |
| CN (1) | CN1311674A (en) |
| AR (1) | AR021172A1 (en) |
| AU (1) | AU5064199A (en) |
| BR (1) | BR9912703A (en) |
| CA (1) | CA2338035A1 (en) |
| EE (1) | EE200100052A (en) |
| HK (1) | HK1039062A1 (en) |
| HU (1) | HUP0102807A2 (en) |
| IL (1) | IL140797A0 (en) |
| IS (1) | IS5816A (en) |
| IT (1) | IT1302125B1 (en) |
| MA (1) | MA26666A1 (en) |
| NO (1) | NO20010532L (en) |
| PL (1) | PL346161A1 (en) |
| SK (1) | SK1252001A3 (en) |
| TN (1) | TNSN99152A1 (en) |
| TR (1) | TR200100333T2 (en) |
| WO (1) | WO2000007581A2 (en) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR100784120B1 (en) | 2000-06-02 | 2007-12-12 | 보드 오브 리전츠, 더 유니버시티 오브 텍사스 시스템 | Ethylenedicysteine (EC) -drug Conjugates |
| US6923960B2 (en) | 2001-10-03 | 2005-08-02 | Vsl Pharmaceuticals Inc. | Antioxidant combination composition and use thereof |
| KR100523562B1 (en) | 2001-10-29 | 2005-10-25 | 한국과학기술연구원 | Neuroprotective composition comprising an extract from opuntia ficus-indica and compounds isolated therefrom |
| JP4527938B2 (en) * | 2002-07-23 | 2010-08-18 | オルビス株式会社 | Orally administered composition for antioxidant |
| JP4334189B2 (en) * | 2002-07-30 | 2009-09-30 | カゴメ株式会社 | AGE production inhibitor |
| ITRM20020620A1 (en) * | 2002-12-13 | 2004-06-14 | Sigma Tau Ind Farmaceuti | USE OF CARNITINE FOR THE PREVENTION AND / OR TREATMENT OF DISORDERS CAUSED BY ANDROPAUSE. |
| ATE423109T1 (en) | 2003-04-14 | 2009-03-15 | Nippon Soda Co | DIAMINE DERIVATIVE, PRODUCTION METHOD AND ANTIOXIDANT DRUGS |
| US9050378B2 (en) | 2003-12-10 | 2015-06-09 | Board Of Regents, The University Of Texas System | N2S2 chelate-targeting ligand conjugates |
| BRPI0507253A (en) * | 2004-01-28 | 2007-06-26 | Nestec Sa | nutritional composition to improve skin conditions and prevent skin diseases |
| US8758723B2 (en) | 2006-04-19 | 2014-06-24 | The Board Of Regents Of The University Of Texas System | Compositions and methods for cellular imaging and therapy |
| US10925977B2 (en) | 2006-10-05 | 2021-02-23 | Ceil>Point, LLC | Efficient synthesis of chelators for nuclear imaging and radiotherapy: compositions and applications |
| RU2619342C1 (en) * | 2016-02-24 | 2017-05-15 | федеральное государственное бюджетное образовательное учреждение высшего образования "Ставропольский государственный аграрный университет" | Medication for prevention and treatment of free radical pathology in animals |
| CN113491687A (en) * | 2020-04-02 | 2021-10-12 | 常州高新技术产业开发区三维工业技术研究所有限公司 | Detoxifying medicine composition and application thereof |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU518617B2 (en) * | 1977-04-29 | 1981-10-08 | Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. | Therapeutic application of acetyl-d, 1-carnitine |
| EP0400547A1 (en) * | 1989-06-02 | 1990-12-05 | Abbott Laboratories | Parenteral nutrition product |
| IT1276225B1 (en) * | 1995-10-17 | 1997-10-27 | Sigma Tau Ind Farmaceuti | PHARMACEUTICAL COMPOSITIONS CONTAINING L-CARNITINE AND ALKANOYL L-CARNITINE IN ASSOCIATION WITH RESVERATROL OR ITS DERIVATIVES USEFUL FOR |
| IT1277953B1 (en) * | 1995-12-21 | 1997-11-12 | Sigma Tau Ind Farmaceuti | PHARMACEUTICAL COMPOSITION CONTAINING L-CARNITINE OR AN ALCANOYL L-CARNITINE AND A 3-OMEGA SERIES POLYUNSATURED ACID USEFUL |
| IT1283967B1 (en) * | 1996-03-29 | 1998-05-07 | Sigma Tau Ind Farmaceuti | USE OF L-CARNITINE OR L-CARNITINE DERIVATIVES AND ANTIOXIDANTS IN THE PREVENTION AND TREATMENT OF PATHOLOGIES ARISING FROM OXIDATIVE DAMAGES |
| US5667791A (en) * | 1996-05-31 | 1997-09-16 | Thione International, Inc. | X-ray induced skin damage protective composition |
| US5895652A (en) * | 1996-07-29 | 1999-04-20 | Longevity Institute International | Method of metabolic adjuvanation and cellular repair |
| AU6141498A (en) * | 1997-02-04 | 1998-08-25 | John V. Kosbab | Compositions and methods for prevention and treatment of vascular degenerative diseases |
| IT1291113B1 (en) * | 1997-03-20 | 1998-12-29 | Sigma Tau Ind Farmaceuti | NUTRITIONAL THERAPEUTIC COMPOSITION FOR SUBJECTS WITH DIABETES MELLITUS |
-
1998
- 1998-08-03 IT IT1998RM000516A patent/IT1302125B1/en active IP Right Grant
-
1999
- 1999-07-29 AU AU50641/99A patent/AU5064199A/en not_active Abandoned
- 1999-07-29 BR BR9912703-2A patent/BR9912703A/en not_active Application Discontinuation
- 1999-07-29 CN CN99809268A patent/CN1311674A/en active Pending
- 1999-07-29 EE EEP200100052A patent/EE200100052A/en unknown
- 1999-07-29 JP JP2000563266A patent/JP2002522382A/en active Pending
- 1999-07-29 HK HK02100334.3A patent/HK1039062A1/en unknown
- 1999-07-29 KR KR1020017001339A patent/KR20010072146A/en not_active Withdrawn
- 1999-07-29 SK SK125-2001A patent/SK1252001A3/en unknown
- 1999-07-29 TR TR2001/00333T patent/TR200100333T2/en unknown
- 1999-07-29 EP EP99935044A patent/EP1102584A2/en not_active Withdrawn
- 1999-07-29 CA CA002338035A patent/CA2338035A1/en not_active Abandoned
- 1999-07-29 WO PCT/IT1999/000251 patent/WO2000007581A2/en not_active Ceased
- 1999-07-29 IL IL14079799A patent/IL140797A0/en unknown
- 1999-07-29 PL PL99346161A patent/PL346161A1/en unknown
- 1999-07-29 HU HU0102807A patent/HUP0102807A2/en unknown
- 1999-07-30 TN TNTNSN99152A patent/TNSN99152A1/en unknown
- 1999-08-03 MA MA25710A patent/MA26666A1/en unknown
- 1999-08-03 AR ARP990103863A patent/AR021172A1/en unknown
-
2001
- 2001-01-16 IS IS5816A patent/IS5816A/en unknown
- 2001-01-31 NO NO20010532A patent/NO20010532L/en not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| SK1252001A3 (en) | 2001-08-06 |
| WO2000007581A2 (en) | 2000-02-17 |
| IL140797A0 (en) | 2002-02-10 |
| AU5064199A (en) | 2000-02-28 |
| EE200100052A (en) | 2002-06-17 |
| WO2000007581A3 (en) | 2000-05-11 |
| NO20010532L (en) | 2001-03-20 |
| IT1302125B1 (en) | 2000-07-31 |
| HUP0102807A2 (en) | 2002-03-28 |
| NO20010532D0 (en) | 2001-01-31 |
| BR9912703A (en) | 2001-05-02 |
| CA2338035A1 (en) | 2000-02-17 |
| ITRM980516A1 (en) | 2000-02-03 |
| IS5816A (en) | 2001-01-16 |
| ITRM980516A0 (en) | 1998-08-03 |
| AR021172A1 (en) | 2002-07-03 |
| KR20010072146A (en) | 2001-07-31 |
| TR200100333T2 (en) | 2001-07-23 |
| PL346161A1 (en) | 2002-01-28 |
| MA26666A1 (en) | 2004-12-20 |
| JP2002522382A (en) | 2002-07-23 |
| CN1311674A (en) | 2001-09-05 |
| EP1102584A2 (en) | 2001-05-30 |
| HK1039062A1 (en) | 2002-04-12 |
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