TNSN98202A1 - Procede nouveau - Google Patents
Procede nouveauInfo
- Publication number
- TNSN98202A1 TNSN98202A1 TNTNSN98202A TNSN98202A TNSN98202A1 TN SN98202 A1 TNSN98202 A1 TN SN98202A1 TN TNSN98202 A TNTNSN98202 A TN TNSN98202A TN SN98202 A TNSN98202 A TN SN98202A TN SN98202 A1 TNSN98202 A1 TN SN98202A1
- Authority
- TN
- Tunisia
- Prior art keywords
- methoxy
- new process
- present
- benzimidazole
- dimethyl
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 3
- WCYWZMWISLQXQU-UHFFFAOYSA-N methyl Chemical class [CH3] WCYWZMWISLQXQU-UHFFFAOYSA-N 0.000 abstract 2
- -1 4-METHOXY-3,5-DIMETHYL-2-PYRIDYL Chemical class 0.000 abstract 1
- SUBDBMMJDZJVOS-UHFFFAOYSA-N 5-methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}-1H-benzimidazole Chemical compound N=1C2=CC(OC)=CC=C2NC=1S(=O)CC1=NC=C(C)C(OC)=C1C SUBDBMMJDZJVOS-UHFFFAOYSA-N 0.000 abstract 1
- RTAQQCXQSZGOHL-UHFFFAOYSA-N Titanium Chemical compound [Ti] RTAQQCXQSZGOHL-UHFFFAOYSA-N 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 229960000381 omeprazole Drugs 0.000 abstract 1
- 239000003960 organic solvent Substances 0.000 abstract 1
- 239000007800 oxidant agent Substances 0.000 abstract 1
- 230000003647 oxidation Effects 0.000 abstract 1
- 238000007254 oxidation reaction Methods 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- XTQHKBHJIVJGKJ-UHFFFAOYSA-N sulfur monoxide Chemical class S=O XTQHKBHJIVJGKJ-UHFFFAOYSA-N 0.000 abstract 1
- 238000003786 synthesis reaction Methods 0.000 abstract 1
- 229910052719 titanium Inorganic materials 0.000 abstract 1
- 239000010936 titanium Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Electrical Discharge Machining, Electrochemical Machining, And Combined Machining (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Saccharide Compounds (AREA)
Abstract
LA PRESENTE INVENTION SE RAPPORTE A UN PROCEDE NOUVEAU POUR LA SYNTHESE DE 5-METHOXY-2-(((4-METHOXY-3,5-DIMETHYL-2-PYRIDYL)METHYL ]SUFINYL)-1H- BENZIMIDAZOLE, CONNU SOUS LE NOM GENERIQUE D'OMEPRAZOLE. LA PRESENTE INVENTION CONCERNE EGALEMENT LA FABRICATION D'UNE PREPARATION PHARMACEUTIQUE CONTENANT LE DIT OMEPRAZOLE AINSI QUE SON USAGE EN MEDECINE. LE PROCEDE NOUVEAU POUR LA PREPARATION DE L'OMEPRAZOLE FAIT APPEL A L'ETAPE DE L'OXYDATION DE 5-METHOXY-2-(((4-METHYOXY-3,5- DIMETHYL-2-PYRIDIYL)METHYL)SULFINYL)-1H-BENZIMIDAZOLE DANS UN SOLVANT ORGANIQUE AVEC UN AGENT OXYDANT EN PRESENCE D'UN COMPLEXE DE TITANE, ET OPTIONNELLEMENT EN PRESENCE D'UNE BASE
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE9704183A SE9704183D0 (sv) | 1997-11-14 | 1997-11-14 | New process |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TNSN98202A1 true TNSN98202A1 (fr) | 2005-03-15 |
Family
ID=20408989
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TNTNSN98202A TNSN98202A1 (fr) | 1997-11-14 | 1998-11-09 | Procede nouveau |
Country Status (35)
| Country | Link |
|---|---|
| US (1) | US6303788B1 (fr) |
| EP (1) | EP0964859A1 (fr) |
| JP (1) | JP2001508466A (fr) |
| KR (1) | KR20000070069A (fr) |
| CN (1) | CN1145624C (fr) |
| AR (1) | AR013740A1 (fr) |
| AU (1) | AU750743B2 (fr) |
| BR (1) | BR9806871A (fr) |
| CA (1) | CA2276753A1 (fr) |
| DE (1) | DE964859T1 (fr) |
| DZ (1) | DZ2641A1 (fr) |
| EE (1) | EE04154B1 (fr) |
| ES (1) | ES2138950T1 (fr) |
| GR (1) | GR990300046T1 (fr) |
| HR (1) | HRP990218A2 (fr) |
| HU (1) | HUP0003737A3 (fr) |
| ID (1) | ID21999A (fr) |
| IL (1) | IL130647A0 (fr) |
| IN (1) | IN190801B (fr) |
| IS (1) | IS5106A (fr) |
| MA (1) | MA26564A1 (fr) |
| MY (1) | MY118199A (fr) |
| NO (1) | NO318197B1 (fr) |
| NZ (1) | NZ336447A (fr) |
| PL (1) | PL334701A1 (fr) |
| RU (1) | RU2211218C2 (fr) |
| SE (1) | SE9704183D0 (fr) |
| SK (1) | SK87299A3 (fr) |
| TN (1) | TNSN98202A1 (fr) |
| TR (1) | TR199901643T1 (fr) |
| TW (1) | TW588046B (fr) |
| UA (1) | UA68342C2 (fr) |
| WO (1) | WO1999025711A1 (fr) |
| YU (1) | YU31199A (fr) |
| ZA (1) | ZA989999B (fr) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE9301830D0 (sv) * | 1993-05-28 | 1993-05-28 | Ab Astra | New compounds |
| US6489346B1 (en) | 1996-01-04 | 2002-12-03 | The Curators Of The University Of Missouri | Substituted benzimidazole dosage forms and method of using same |
| US5840737A (en) | 1996-01-04 | 1998-11-24 | The Curators Of The University Of Missouri | Omeprazole solution and method for using same |
| IL142703A (en) | 1998-11-10 | 2006-04-10 | Astrazeneca Ab | Crystalline form of omeprazole |
| UA72748C2 (en) | 1998-11-10 | 2005-04-15 | Astrazeneca Ab | A novel crystalline form of omeprazole |
| CA2436467A1 (fr) * | 2001-02-02 | 2002-08-15 | Teva Pharmaceutical Industries Ltd. | Procedes de production de 2-(2-pyridylmethyl) sulfinyl-1h-benzimidazoles substitues |
| SE0203092D0 (en) | 2002-10-18 | 2002-10-18 | Astrazeneca Ab | Method for the synthesis of a benzimidazole compound |
| US8993599B2 (en) | 2003-07-18 | 2015-03-31 | Santarus, Inc. | Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them |
| US8906940B2 (en) | 2004-05-25 | 2014-12-09 | Santarus, Inc. | Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them |
| SI1802584T1 (sl) * | 2004-10-11 | 2010-01-29 | Ranbaxy Lab Ltd | Postopki za pripravo substituiranih sulfoksidov |
| EP1801110A1 (fr) | 2005-12-22 | 2007-06-27 | KRKA, tovarna zdravil, d.d., Novo mesto | Sel d'arginine d'ésoméprazole |
| CN1810803B (zh) * | 2006-02-17 | 2010-11-17 | 中国科学院上海有机化学研究所 | 高对映体选择性制备(s)-奥美拉唑的方法 |
| CN101538264A (zh) * | 2008-03-19 | 2009-09-23 | 中国科学院成都有机化学有限公司 | 手性亚砜类化合物的制备新方法 |
| CN102603621B (zh) * | 2012-02-07 | 2013-09-04 | 成都苑东药业有限公司 | 一种新型手性亚砜化合物和以该化合物制备埃索美拉唑钠的方法 |
| CN106083819A (zh) * | 2016-06-08 | 2016-11-09 | 扬子江药业集团有限公司 | 一种奥美拉唑的制备方法 |
| ES2948511A1 (es) * | 2021-09-08 | 2023-09-13 | Fundacion Para La Investigacion Biomedica Del Hospital Univ De La Princesa | Derivados de n-sulfonilureas y su uso terapeutico |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE7804231L (sv) * | 1978-04-14 | 1979-10-15 | Haessle Ab | Magsyrasekretionsmedel |
| FI95572C (fi) * | 1987-06-22 | 1996-02-26 | Eisai Co Ltd | Menetelmä lääkeaineena käyttökelpoisen piperidiinijohdannaisten tai sen farmaseuttisen suolan valmistamiseksi |
| SE9002043D0 (sv) | 1990-06-07 | 1990-06-07 | Astra Ab | Improved method for synthesis |
| WO1993006097A1 (fr) | 1991-09-20 | 1993-04-01 | Merck & Co., Inc. | Nouveau procede de preparation d'agents anti-ulcereux |
| SE504459C2 (sv) * | 1994-07-15 | 1997-02-17 | Astra Ab | Förfarande för framställning av substituerade sulfoxider |
-
1997
- 1997-11-14 SE SE9704183A patent/SE9704183D0/xx unknown
-
1998
- 1998-03-11 UA UA99073870A patent/UA68342C2/uk unknown
- 1998-11-02 MY MYPI98004977A patent/MY118199A/en unknown
- 1998-11-02 ZA ZA989999A patent/ZA989999B/xx unknown
- 1998-11-02 AR ARP980105504A patent/AR013740A1/es unknown
- 1998-11-02 TW TW087118172A patent/TW588046B/zh not_active IP Right Cessation
- 1998-11-02 IN IN3213DE1998 patent/IN190801B/en unknown
- 1998-11-03 WO PCT/SE1998/001984 patent/WO1999025711A1/fr not_active Ceased
- 1998-11-03 BR BR9806871-7A patent/BR9806871A/pt not_active Application Discontinuation
- 1998-11-03 IL IL13064798A patent/IL130647A0/xx not_active IP Right Cessation
- 1998-11-03 CA CA002276753A patent/CA2276753A1/fr not_active Abandoned
- 1998-11-03 NZ NZ336447A patent/NZ336447A/en unknown
- 1998-11-03 HR HR990218A patent/HRP990218A2/hr not_active Application Discontinuation
- 1998-11-03 CN CNB988017970A patent/CN1145624C/zh not_active Expired - Fee Related
- 1998-11-03 RU RU99117541/04A patent/RU2211218C2/ru not_active IP Right Cessation
- 1998-11-03 TR TR1999/01643T patent/TR199901643T1/xx unknown
- 1998-11-03 JP JP52827799A patent/JP2001508466A/ja not_active Ceased
- 1998-11-03 DE DE0964859T patent/DE964859T1/de active Pending
- 1998-11-03 YU YU31199A patent/YU31199A/sh unknown
- 1998-11-03 US US09/194,647 patent/US6303788B1/en not_active Expired - Fee Related
- 1998-11-03 ES ES98953132T patent/ES2138950T1/es active Pending
- 1998-11-03 SK SK872-99A patent/SK87299A3/sk unknown
- 1998-11-03 ID IDW990692A patent/ID21999A/id unknown
- 1998-11-03 EE EEP199900391A patent/EE04154B1/xx not_active IP Right Cessation
- 1998-11-03 PL PL98334701A patent/PL334701A1/xx unknown
- 1998-11-03 AU AU10582/99A patent/AU750743B2/en not_active Ceased
- 1998-11-03 DZ DZ980251A patent/DZ2641A1/fr active
- 1998-11-03 HU HU0003737A patent/HUP0003737A3/hu unknown
- 1998-11-03 EP EP98953132A patent/EP0964859A1/fr not_active Ceased
- 1998-11-03 KR KR1019997006290A patent/KR20000070069A/ko not_active Abandoned
- 1998-11-05 MA MA25335A patent/MA26564A1/fr unknown
- 1998-11-09 TN TNTNSN98202A patent/TNSN98202A1/fr unknown
-
1999
- 1999-07-02 IS IS5106A patent/IS5106A/is unknown
- 1999-07-02 NO NO19993298A patent/NO318197B1/no unknown
-
2000
- 2000-07-31 GR GR990300046T patent/GR990300046T1/el unknown
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| TNSN98202A1 (fr) | Procede nouveau | |
| Chankeshwara et al. | Catalyst-free chemoselective N-tert-butyloxycarbonylation of amines in water | |
| MY120745A (en) | Novel form of s-omeprazole | |
| TNSN00104A1 (fr) | Derives d'isothiazole nouveaux, procede pour leur preparation et compositions pharmaceutiques les contenant | |
| DE60138468D1 (de) | Cyanophenoxy-carbonsäuren und zusammensetzungen für die freisetzung aktiver substanzen | |
| TR200200008T2 (tr) | Fenofibratı ihtiva eden farmasötik bileşim ve bu bileşimin hazırlanması için yöntem | |
| CA2174033A1 (fr) | Nouveaux composes pyridiniques, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent | |
| TNSN97110A1 (fr) | Derives de 2-(2-oxo-ethylidene)-imidazolidine-4-one, procede pour leur preparation et compositions pharmaceutiques les contenant | |
| TNSN00228A1 (fr) | Derives de benzimidazole nouveaux, et compositions les contenant | |
| AU2002360188A1 (en) | Capsule with fast content solubilization and release | |
| TNSN98004A1 (fr) | Derives de quinoleine et derives de quinazoline nouveaux, procede pour leur preparation et compositions pharmaceutiques les contenant | |
| BR9810197A (pt) | Produto, compostos, processo de preparação destes, composição farmacêutica, e, utilização de um produto | |
| TNSN00108A1 (fr) | Derives d'erythromycine nouveaux, procede pour leur preparation et compositions pharmaceutiques les contenant | |
| PT92168B (pt) | Processo para a preparacao de composicoes farmaceuticas contendo derivados de nucleos de estrogenios para provocar a inibicao da actividade de esteroides sexuais | |
| RU99117541A (ru) | Новый способ | |
| MA26725A1 (fr) | Derives de resorcinol, compositions pharmaceutiques les contenant et procede pour leur preparation | |
| SI1095037T1 (en) | Process of synthesis of 5-methoxy- 2- (4-methoxy- 3,5-dimethyl- 2-pyridyl)methyl)sulfinyl-1h-benzimidazole | |
| US6229021B1 (en) | Method of omeprazole preparation | |
| IL146746A0 (en) | New process for the purification of aldehyde impurities | |
| Kim et al. | α-Iodination of enaminones using the modified Johnson's procedure: the use of I2 and Et3N | |
| TNSN00105A1 (fr) | Derives de 1-trifluoromethyl-4-hydroxy-7-piperidinyl- aminomethylchromane, procede pour leur preparation et compositions pharmaceutiques les contenant | |
| WO2002092565A3 (fr) | Composes | |
| TNSN00095A1 (fr) | Benzolactames et thioamides cycliques substitues nouveaux, procede pour leur preparation et compositions pharmaceutiques les contenant | |
| TH58464A (th) | กรรมวิธีใหม่ | |
| ATE254460T1 (de) | Anhydrovinblastin zur behandlung von krebs |