TN2014000321A1 - Pharmaceutical compositions containing dimethyl fumarate - Google Patents
Pharmaceutical compositions containing dimethyl fumarateInfo
- Publication number
- TN2014000321A1 TN2014000321A1 TNP2014000321A TN2014000321A TN2014000321A1 TN 2014000321 A1 TN2014000321 A1 TN 2014000321A1 TN P2014000321 A TNP2014000321 A TN P2014000321A TN 2014000321 A TN2014000321 A TN 2014000321A TN 2014000321 A1 TN2014000321 A1 TN 2014000321A1
- Authority
- TN
- Tunisia
- Prior art keywords
- dimethyl fumarate
- compositions containing
- compositions
- pharmaceutical compositions
- containing dimethyl
- Prior art date
Links
- LDCRTTXIJACKKU-ONEGZZNKSA-N dimethyl fumarate Chemical compound COC(=O)\C=C\C(=O)OC LDCRTTXIJACKKU-ONEGZZNKSA-N 0.000 title abstract 3
- 229960004419 dimethyl fumarate Drugs 0.000 title abstract 3
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 239000000203 mixture Substances 0.000 abstract 4
- 150000001875 compounds Chemical class 0.000 abstract 1
- NKHAVTQWNUWKEO-UHFFFAOYSA-N fumaric acid monomethyl ester Natural products COC(=O)C=CC(O)=O NKHAVTQWNUWKEO-UHFFFAOYSA-N 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- NKHAVTQWNUWKEO-NSCUHMNNSA-N monomethyl fumarate Chemical compound COC(=O)\C=C\C(O)=O NKHAVTQWNUWKEO-NSCUHMNNSA-N 0.000 abstract 1
- 229940005650 monomethyl fumarate Drugs 0.000 abstract 1
- 201000006417 multiple sclerosis Diseases 0.000 abstract 1
- 230000004770 neurodegeneration Effects 0.000 abstract 1
- 208000015122 neurodegenerative disease Diseases 0.000 abstract 1
- 238000011321 prophylaxis Methods 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Landscapes
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Provided herein are compositions containing compounds, or pharmaceutically acceptable salts, that metabolize to monomethyl fumarate with certain pharmacokinetic parameters and methods for treating, prophylaxis, or amelioration of neurodegenerative diseases including multiple sclerosis using such compositions in a subject, wherein if the compositions contain dimethyl fumarate, the total amount of dimethyl fumarate in the compositions ranges from about 43% w/w to about 95% w/w.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261723048P | 2012-11-06 | 2012-11-06 | |
| PCT/US2013/024946 WO2013119677A1 (en) | 2012-02-07 | 2013-02-06 | Pharmaceutical compositions containing dimethyl fumarate |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TN2014000321A1 true TN2014000321A1 (en) | 2015-12-21 |
Family
ID=55447224
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TNP2014000321A TN2014000321A1 (en) | 2012-11-06 | 2014-07-24 | Pharmaceutical compositions containing dimethyl fumarate |
Country Status (1)
| Country | Link |
|---|---|
| TN (1) | TN2014000321A1 (en) |
-
2014
- 2014-07-24 TN TNP2014000321A patent/TN2014000321A1/en unknown
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