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TN2011000593A1 - Substituted aminobutyric derivatives as neprilysin inhibitors - Google Patents

Substituted aminobutyric derivatives as neprilysin inhibitors

Info

Publication number
TN2011000593A1
TN2011000593A1 TNP2011000593A TN2011000593A TN2011000593A1 TN 2011000593 A1 TN2011000593 A1 TN 2011000593A1 TN P2011000593 A TNP2011000593 A TN P2011000593A TN 2011000593 A TN2011000593 A TN 2011000593A TN 2011000593 A1 TN2011000593 A1 TN 2011000593A1
Authority
TN
Tunisia
Prior art keywords
neprilysin inhibitors
derivatives
substituted
substituted aminobutyric
aminobutyric derivatives
Prior art date
Application number
TNP2011000593A
Inventor
Gary Mark Coppola
Yuki Iwaki
Rajeshri Ganesh Karki
Toshio Kawanami
Gary Michael Ksander
Muneto Migi
Robert Sun
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/EP2010/057213 external-priority patent/WO2010136474A2/en
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of TN2011000593A1 publication Critical patent/TN2011000593A1/en

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

The present invention provides a compound of formula (I') or a pharmaceutically acceptable salt thereof, wherein R1, R2, R3, X and n are defined herein. The invention also relates to a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.
TNP2011000593A 2009-05-28 2011-11-21 Substituted aminobutyric derivatives as neprilysin inhibitors TN2011000593A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US18175309P 2009-05-28 2009-05-28
PCT/EP2010/057213 WO2010136474A2 (en) 2009-05-28 2010-05-26 Substituted aminobutyric derivatives as neprilysin inhibitors

Publications (1)

Publication Number Publication Date
TN2011000593A1 true TN2011000593A1 (en) 2013-05-24

Family

ID=59772201

Family Applications (1)

Application Number Title Priority Date Filing Date
TNP2011000593A TN2011000593A1 (en) 2009-05-28 2011-11-21 Substituted aminobutyric derivatives as neprilysin inhibitors

Country Status (1)

Country Link
TN (1) TN2011000593A1 (en)

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