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Priority claimed from PCT/CN2010/070780external-prioritypatent/WO2010097052A1/en
Application filed by Servier LabfiledCriticalServier Lab
Publication of TN2011000425A1publicationCriticalpatent/TN2011000425A1/en
Acyclic And Carbocyclic Compounds In Medicinal Compositions
(AREA)
Abstract
Agomelatine hydrohalide complex and preparation method thereof are disclosed. Compared with agomelatine, agomelatine hydrohalide complex obtained by the present method has improved solubility, and is suitable for application need of preparation of finished products of drugs. Furthermore, the product has good stability and high purity. The preparation process is simple and convenient, and the product with high purity can be obtained without special operations.
TN2011000425A2009-02-272011-08-17Agomelatine hydrohalide complex and preparation method thereof
TN2011000425A1
(en)
Process for the synthesis of 3-(2-bromo-4,5-dimethoxyphenyl)propanenitrile, and application in the synthesis of ivabradine and addition salts threof with a pharmaceutically acceptable acid