TN2010000402A1 - Pim kinase inhibitors and methods of their use - Google Patents
Pim kinase inhibitors and methods of their useInfo
- Publication number
- TN2010000402A1 TN2010000402A1 TNP2010000402A TN2010000402A TN2010000402A1 TN 2010000402 A1 TN2010000402 A1 TN 2010000402A1 TN P2010000402 A TNP2010000402 A TN P2010000402A TN 2010000402 A TN2010000402 A TN 2010000402A TN 2010000402 A1 TN2010000402 A1 TN 2010000402A1
- Authority
- TN
- Tunisia
- Prior art keywords
- methods
- new compounds
- kinase inhibitors
- pim kinase
- pharmaceutically acceptable
- Prior art date
Links
- 229940043355 kinase inhibitor Drugs 0.000 title 1
- 239000003757 phosphotransferase inhibitor Substances 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 3
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 108091000080 Phosphotransferase Proteins 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 230000005764 inhibitory process Effects 0.000 abstract 1
- 239000002207 metabolite Substances 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 102000020233 phosphotransferase Human genes 0.000 abstract 1
- 239000000651 prodrug Substances 0.000 abstract 1
- 229940002612 prodrug Drugs 0.000 abstract 1
- 238000011321 prophylaxis Methods 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 229940124597 therapeutic agent Drugs 0.000 abstract 1
- 238000011282 treatment Methods 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
The present invention relates to new compounds of Formulas (I) and (II), their tautomers, stereoisomers and polymorphs, and pharmaceutically acceptable salts, esters, metabolites or prodrugs thereof, compositions of the new compounds together with pharmaceutically acceptable carriers, and uses of the new compounds, either alone or in combination with at least one additional therapeutic agent, in the inhibition of Pirn kinase activity and/or the prophylaxis or treatment of cancer.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/EP2009/052506 WO2009109576A1 (en) | 2008-03-03 | 2009-03-03 | Pim kinase inhibitors and methods of their use |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TN2010000402A1 true TN2010000402A1 (en) | 2011-12-29 |
Family
ID=55024524
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TNP2010000402A TN2010000402A1 (en) | 2009-03-03 | 2010-09-01 | Pim kinase inhibitors and methods of their use |
Country Status (1)
| Country | Link |
|---|---|
| TN (1) | TN2010000402A1 (en) |
-
2010
- 2010-09-01 TN TNP2010000402A patent/TN2010000402A1/en unknown
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