TH87783B - A transdermal drug delivery device with O-desmethyl venlafazine (ODV) or its salt - Google Patents
A transdermal drug delivery device with O-desmethyl venlafazine (ODV) or its saltInfo
- Publication number
- TH87783B TH87783B TH601004217A TH0601004217A TH87783B TH 87783 B TH87783 B TH 87783B TH 601004217 A TH601004217 A TH 601004217A TH 0601004217 A TH0601004217 A TH 0601004217A TH 87783 B TH87783 B TH 87783B
- Authority
- TH
- Thailand
- Prior art keywords
- odv
- delivery device
- drug delivery
- transdermal drug
- salt
- Prior art date
Links
- 150000003839 salts Chemical class 0.000 title claims abstract 3
- 238000013271 transdermal drug delivery Methods 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 claims 3
- 238000010521 absorption reaction Methods 0.000 claims 2
- 230000000699 topical effect Effects 0.000 claims 2
- 239000007933 dermal patch Substances 0.000 claims 1
- 239000003623 enhancer Substances 0.000 claims 1
- 239000000546 pharmaceutical excipient Substances 0.000 claims 1
- 238000011287 therapeutic dose Methods 0.000 claims 1
- QZAYGJVTTNCVMB-UHFFFAOYSA-N serotonin Chemical compound C1=C(O)C=C2C(CCN)=CNC2=C1 QZAYGJVTTNCVMB-UHFFFAOYSA-N 0.000 abstract 2
- 208000019901 Anxiety disease Diseases 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 230000008030 elimination Effects 0.000 abstract 1
- 238000003379 elimination reaction Methods 0.000 abstract 1
- 230000001815 facial effect Effects 0.000 abstract 1
- 239000003112 inhibitor Substances 0.000 abstract 1
- 229940076279 serotonin Drugs 0.000 abstract 1
- 208000011580 syndromic disease Diseases 0.000 abstract 1
- 230000009885 systemic effect Effects 0.000 abstract 1
- 238000011282 treatment Methods 0.000 abstract 1
- 230000002792 vascular Effects 0.000 abstract 1
Abstract
การประดิษฐ์นี้ให้อุปกรณ์การนำส่งยาผ่านผิวหนัง (ได้แก่, แผ่นปะ) ซึ่งประกอบรวมด้วย O- เดสเมทิลเวนลาฟาซีน (ODV), สารยับยั้งการดูดขึ้นใหม่ของเซอโรโทนินและโนรีพีนฟรีนแบบเลือก, หรือเกลือที่ยอมรับได้ทางเภสัชกรรมของมัน, ซึ่งในหมู่อื่น, เสนอประโยชน์ของการกำจัดหรือการลด ผลข้างเคียงที่เกี่ยวเนื่องกับการให้ทางปากของ ODV ยังให้วิธีการของการเตรียมและการใช้ระบบการ นำส่งผ่านผิวหน้าเหล่านี้สำหรับการบำบัดภาวะซึมเศร้า, ความผิดปกติของความกระวนกระวาย, กลุ่ม อาการปรับขนาดหลอดเลือดและความเจ็บปวด The invention provides a transdermal drug delivery device (ie, patch) consisting of O-Desmethylvenlaphazine (ODV), serotonin reconstitution inhibitors and free norepine. Of selective, or its pharmacologically acceptable salt, which, among others, offers the benefit of elimination or reduction Side effects associated with oral administration of ODV also provide a means of preparation and systemic use. These are delivered through these facial skin treatments for depression, anxiety disorders, vascular resization syndrome and pain.
Claims (3)
Publications (2)
| Publication Number | Publication Date |
|---|---|
| TH87783A TH87783A (en) | 2007-11-30 |
| TH87783B true TH87783B (en) | 2007-11-30 |
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