TH5472A - Peptide preparation - Google Patents
Peptide preparationInfo
- Publication number
- TH5472A TH5472A TH8701000681A TH8701000681A TH5472A TH 5472 A TH5472 A TH 5472A TH 8701000681 A TH8701000681 A TH 8701000681A TH 8701000681 A TH8701000681 A TH 8701000681A TH 5472 A TH5472 A TH 5472A
- Authority
- TH
- Thailand
- Prior art keywords
- insulin
- preparing
- peptide preparation
- derivatives
- molar
- Prior art date
Links
- 238000002360 preparation method Methods 0.000 title claims 2
- 108090000765 processed proteins & peptides Proteins 0.000 title 1
- NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 claims abstract 8
- 102000004877 Insulin Human genes 0.000 claims abstract 4
- 108090001061 Insulin Proteins 0.000 claims abstract 4
- 229940125396 insulin Drugs 0.000 claims abstract 4
- JLVVSXFLKOJNIY-UHFFFAOYSA-N Magnesium ion Chemical compound [Mg+2] JLVVSXFLKOJNIY-UHFFFAOYSA-N 0.000 claims abstract 2
- 229910001425 magnesium ion Inorganic materials 0.000 claims abstract 2
- FYYHWMGAXLPEAU-UHFFFAOYSA-N Magnesium Chemical compound [Mg] FYYHWMGAXLPEAU-UHFFFAOYSA-N 0.000 claims 1
- 229940079593 drug Drugs 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 229910052749 magnesium Inorganic materials 0.000 claims 1
- 239000011777 magnesium Substances 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 238000000034 method Methods 0.000 claims 1
- 239000013049 sediment Substances 0.000 claims 1
Abstract
ยาปรุงสำเร็จอินซูลินที่มีคุณสมบัติดีขึ้นสำหรับการใช้ที่ไม่ใช่ทางปาก สามารถเตรียมได้ที่ค่าพีเอชประมาณ 3 ถึง 8.5 ในสภาวะที่มีแมกนีเซียมไอออน ความเข้มข้นประมาณ 0.005 ถึง 0.5 โมลาร์ สิทธิบัตรยา Enhanced insulin flavoring for non-oral use. It can be prepared at a PH value of 3 to 8.5 in the presence of magnesium ions. The concentration is approximately 0.005 to 0.5 molar.
Claims (2)
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TH5472A true TH5472A (en) | 1989-01-03 |
Family
ID=
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