TH4776A - New quinoline derivatives and processes for their preparation - Google Patents
New quinoline derivatives and processes for their preparationInfo
- Publication number
- TH4776A TH4776A TH8701000224A TH8701000224A TH4776A TH 4776 A TH4776 A TH 4776A TH 8701000224 A TH8701000224 A TH 8701000224A TH 8701000224 A TH8701000224 A TH 8701000224A TH 4776 A TH4776 A TH 4776A
- Authority
- TH
- Thailand
- Prior art keywords
- group
- small
- alkyl
- chemical formula
- hydrogen atom
- Prior art date
Links
- 125000002943 quinolinyl group Chemical class N1=C(C=CC2=CC=CC=C12)* 0.000 title claims abstract 3
- 229940027991 antiseptic and disinfectant quinoline derivative Drugs 0.000 title claims 2
- 125000000217 alkyl group Chemical group 0.000 claims abstract 10
- 239000000126 substance Substances 0.000 claims abstract 9
- 125000004435 hydrogen atom Chemical group [H]* 0.000 claims abstract 8
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 claims abstract 4
- 125000003277 amino group Chemical group 0.000 claims abstract 3
- 125000001188 haloalkyl group Chemical group 0.000 claims abstract 3
- 229940079593 drug Drugs 0.000 claims abstract 2
- 239000003814 drug Substances 0.000 claims abstract 2
- 125000005843 halogen group Chemical group 0.000 claims abstract 2
- 125000000623 heterocyclic group Chemical group 0.000 claims abstract 2
- 229910052757 nitrogen Inorganic materials 0.000 claims abstract 2
- YZCKVEUIGOORGS-UHFFFAOYSA-N Hydrogen atom Chemical compound [H] YZCKVEUIGOORGS-UHFFFAOYSA-N 0.000 claims 1
- 125000004429 atom Chemical group 0.000 claims 1
- 230000000844 anti-bacterial effect Effects 0.000 abstract 1
- 239000003899 bactericide agent Substances 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Abstract
การประดิษฐ์นี้เกี่ยวข้องกับอนุพันธ์ควิโนลีนที่มีสูตร(สูตรเคมี) ซึ่งZคือหมู่อะมิโนหรือเฮโลเจนอะตอม, Rคือ(สูตรเคมี) หรือ(สูตรเคมี) ซึ่งR1คือไฮโดรเจนอะตอม,หมู่แอลคิลหรือเฮโลแอลคิลขนาด เล็กR2คือไฮโดรเจนอะตอมหรือหมู่แอลคิลขนาดเล็ก,R3คือหมู่ แอลคิลหรือเฮโลแอลคิลขนาดเล็ก,R4คือไฮโดรเจนอะตอมหรือหมู่ แอลคิลขนาดเล็ก,R5และR6เหมือนกันหรือแตกต่างกันได้และแต่ละ หมู่นี้แทนไฮโดรเจนอะตอมหรือหมู่แอลคิลขนาด เล็ก,หรือR5และR6รวมเข้ากับไนโตรเจน ที่ต่ออยู่ด้วยเกิดเป็นเฮเทอโรไซคลิค ริง,และnคือ0หรือ1พร้อมกับข้อแม้ว่าเมื่อZเป็นหมู่อะมิโน แล้ว,Rคือ(B); หรือเอสเทอร์ต่างๆของสารนั้นและเกลือต่างๆของสารนั้นและ กรรมวิธีต่างๆสำหรับการเตรียมของสารนั้นสารประกอบต่างๆ เหล่านี้แสดงการออกฤทธิ์ทำลายแบคทีเรียได้ดีเยี่ยมและใช้ ประโยชน์เป็นสารทำลายแบคทีเรีย สิทธิบัตรยา The invention involved a quinoline derivative with the formula (chemical formula), where Z is an amino group or halogen atom, R is (chemical formula) or (chemical formula) where R1 is a hydrogen atom, an alkyl group or Halo alkyl size R2 is a hydrogen atom or a small alkyl group, R3 is a group. Small alkyl or haloalkyl, R4 is a hydrogen atom or group. Small alkyls, R5 and R6 can be the same or different, and each This group represents hydrogen atoms or large alkyl groups. Small, or R5 and R6 combine with nitrogen. Connected to the formation of heterocyclic Ring, and n are 0 or 1, along with the clause when Z is an amino group. Then, R is (B); Or various esters of that substance and salts of that substance and Processes for the preparation of the substance; They exhibit excellent bactericidal action and are used Useful as a bactericidal substance, patent drug
Claims (1)
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TH4776A true TH4776A (en) | 1988-04-01 |
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