TH154821A - Fudge ring quinolil pyrolopyrimidil compound Or the salt of this substance - Google Patents
Fudge ring quinolil pyrolopyrimidil compound Or the salt of this substanceInfo
- Publication number
- TH154821A TH154821A TH1401004803A TH1401004803A TH154821A TH 154821 A TH154821 A TH 154821A TH 1401004803 A TH1401004803 A TH 1401004803A TH 1401004803 A TH1401004803 A TH 1401004803A TH 154821 A TH154821 A TH 154821A
- Authority
- TH
- Thailand
- Prior art keywords
- compound
- substance
- salt
- pyrolopyrimidil
- quinolil
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title claims abstract 6
- 239000000126 substance Substances 0.000 title claims abstract 5
- 150000003839 salts Chemical class 0.000 title claims abstract 3
- 230000002401 inhibitory effect Effects 0.000 claims abstract 6
- 102000052116 epidermal growth factor receptor activity proteins Human genes 0.000 claims abstract 4
- 108700015053 epidermal growth factor receptor activity proteins Proteins 0.000 claims abstract 4
- YOHYSYJDKVYCJI-UHFFFAOYSA-N n-[3-[[6-[3-(trifluoromethyl)anilino]pyrimidin-4-yl]amino]phenyl]cyclopropanecarboxamide Chemical compound FC(F)(F)C1=CC=CC(NC=2N=CN=C(NC=3C=C(NC(=O)C4CC4)C=CC=3)C=2)=C1 YOHYSYJDKVYCJI-UHFFFAOYSA-N 0.000 claims abstract 4
- 206010028980 Neoplasm Diseases 0.000 claims abstract 2
- 201000011510 cancer Diseases 0.000 claims abstract 2
- 230000010261 cell growth Effects 0.000 claims abstract 2
- 239000003814 drug Substances 0.000 claims abstract 2
- 239000000825 pharmaceutical preparation Substances 0.000 claims abstract 2
- 230000002265 prevention Effects 0.000 claims abstract 2
- 229940079593 drug Drugs 0.000 claims 1
Abstract
DC60 (26/06/60) การประดิษฐ์นี้จัดให้มีสารประกอบใหม่ที่มีฤทธิ์ในการยับยั้งต่อ EGFR เเละมีผลในการยับยั้ง การเติบโตของเซล การประดิษฐ์นี้ยังจัดให้มีสารเตรียมทางเภสัชกรรมที่มีประโยชน์สำหรับการ ป้องกัน เเละ/หรือ การรักษามะเร็งโดยมีพื้นฐานอยู่บนผลการยับยั้ง EGFR ของสารประกอบนี้ โดย สารประกอบนี้เเสดงได้ด้วยสูตร (I) ต่อไปนี้ สูตรเคมี (I) หรือเกลือของสารนี้ สิทธิบัตรยา DC60 (26/06/60) This invention provides a new compound with an inhibitory effect on EGFR and has an inhibitory effect. Cell growth The invention also provides a useful pharmaceutical preparation for the prevention and / or treatment of cancer based on the EGFR-inhibiting effect of this compound. This chemical formula (I) or the salt of this substance, patent medicine.
Claims (1)
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TH154821A true TH154821A (en) | 2016-08-01 |
Family
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