TH10936C3 - "Composition of modified liposomes that hold proteins, silk glue extracted from boiled water, silk glue (Modified-Liposome composition of silk protein extracted from silk degumming wastewater) - Google Patents

Abstract

New Request, Update 8/22/2016 This invention relates to the development of a component of the permanganate lysomal that holds protein, silk glue that It was extracted from boiled water to obtain suitable properties for powder drying by sprsy- Drying by modifying the liposome chromatography. Polyvinyl alcohol (Polyvinyl alcohol; PVA), Polyvinylpyrrolidone (Polyvinylpyrrolidone; PVP), Polyacrylic acid (PAA), Polyethylene glycol (PEG) The composition of the liposomes according to this invention consists of a). Silk glue protein extracted from bruise, boiled glue, b. Phosphatidylcholine and cholesterol in a mole ratio of 4-20 1 and c) polymers of choice from the group containing polyvinyl alcohol ( Polyvinyl alcohol; PVA), Polyvinylpyrrolidone (Polyvinylpyrrolidone; PVP), polyacrylic acid (PAA), polyethylene glycol (PEG) and their ingredients are also involved. With the preparation of liposome particles that store protein, silk glue that consists of Preparation of a fatty solution containing phosphatidylcholine and cholesterol In organic destroyers Where the mole ratio of phosphatidylcholine to cholesterol is 4-20: 1 by mole, evaporation of the organic solvent from the fat solution. Will get a fat film containing Phosphatidylcholine and cholesterol, mixing the aforementioned lipid films with polymer and adhesive protein solutions. Silk extracted from boiled water glues together to obtain a solution of the combined fat, polymer and glued protein. From the water boiled glue silk And the last step is The process of reducing the particle size of a solution of fat, polymer and silk protein extracted from boiled water. Will get liposomes that retain silk proteins extracted from boiled water Silk glue as a suspension that can protect the active ingredient, herein is the sericin protein contained in the adhesive protein. Silk extracted from boiled water, silk glue is stable and can withstand the heat from the drying process. Drying method can spray. It also has the ability to contain the active substance and control the release of the substance. It is active for up to 72 hours. This invention process may also consist of a spray drying process. To obtain a dry powder liposome, the preparation of modified liposome particles, protein retention, silk glues extracted from water. Boiled silk glue in dry powder form can be applied in various industries. Especially in the industry Cosmetics effectively In addition, this invention is also the use of silk protein glue from boiled water. Which is usually waste during the silkworm process / silk production to be utilized and added value, also encouraging farmers who raise the silkworm to realize and value more:

Claims (3)

Disclaimer (all) which will not appear on the advertisement page. : New requests updated 22/8/2016 1. The composition of the loposome containing the silk protein glues extracted from boiled water. Containing Silk glue protein extracted from boiled water, glues, fat containing Phosphatidylcholine And cholesterol The mole ratio was 4-20 to 1. The polymer was selected from the group containing Polyvinyl alcohol (Polyvinyl alcohol; PVA), Polyvinylpyrrolidone (Polyvinylpyrrolidone; PVP), polyacrylic acid (Polyacrylic acid; PAA), polyethylene glycol (PEG) and a mixture thereof; And water 2. Composition of liposome retaining silk proteins extracted from boiled water. According to claim 1, the appropriate silk protein contains 0.05-5% of silk protein extracted from boiled water, fat containing cholesterol and phosphatidylcholine. In the mole ratio of 4-20 to 1, the total volume of 0.5-10 percent by weight Selective polymers from the articulated group Polyvinyl alcohol (Polyvinyl alcohol; PVA), Polyvinylpyrrolidone (Polyvinylpyrrolidone; PVP), polyacrylic acid (Polyacrylic acid; PAA), polyethylene glycol (Polyethylene glycol; PEG) 0.5-5% by weight; And water 80-89 percent by weight 3. The preparation process of liposome containing proteins, silk glue extracted from boiled water, silk glue. According to claim 1 that includes a procedure Preparation of a fat solution containing phosphatidylcholine and cholesterol in organic solvents. Where the molar ratio of Phosphatidylcholine and cholesterol are in the 4-20 to 1 range, with the mole of the organic disintegrating from the lipid solution, resulting in a lipid film containing phosphatides. S Fatidylcholine and cholesterol By mixing these fatty films, polymers, and dissolving silk proteins extracted from boiled water together, the coupling agent of lipid, polymer and silk protein was extracted from boiled water. Silk glue By reducing the particle size of the fat, polymers and silk proteins extracted from the boiled water, the silk glue protein contained liposome particles that contained the silk glue proteins extracted from the boiled water were suspended in the water.