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SV2002000776A - Nuevas imidazotriazinonas sustituidas ref.lea 34 985-sv - Google Patents

Nuevas imidazotriazinonas sustituidas ref.lea 34 985-sv

Info

Publication number
SV2002000776A
SV2002000776A SV2001000776A SV2001000776A SV2002000776A SV 2002000776 A SV2002000776 A SV 2002000776A SV 2001000776 A SV2001000776 A SV 2001000776A SV 2001000776 A SV2001000776 A SV 2001000776A SV 2002000776 A SV2002000776 A SV 2002000776A
Authority
SV
El Salvador
Prior art keywords
lea
ref
new substituted
substituted imidazotriazinones
imidazotriazinones
Prior art date
Application number
SV2001000776A
Other languages
English (en)
Inventor
Ulrich Niewohner
Dagmer Schauss
Martin Hendrix
Gerhard Konig
Frank Gerhard Boss
Der Staay Franz Josef Van
Rudy Schreiber
Karl-Heinz Schlemmer
Rolf Grosser
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of SV2002000776A publication Critical patent/SV2002000776A/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/53Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Epidemiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

LA PRESENTE INVENCION SE REFIERE A NUEVAS IMIDAZOTRIAZINONAS SUSTITUIDAS, A PROCEDIMIENTOS PARA SU PREPARACION Y A SU USO PARA LA PREPARACION DE MEDICAMENTOS, ESPECIALMENTE PARA LA MEJORA E LA PERCEPCION, LA CAPACIDAD DE CONCENTRACION, LA CAPACIDAD DE APRENDIZAJE Y/O LA CAPACIDAD DE MEMORIA.
SV2001000776A 2000-12-21 2001-12-20 Nuevas imidazotriazinonas sustituidas ref.lea 34 985-sv SV2002000776A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE10064105A DE10064105A1 (de) 2000-12-21 2000-12-21 Neue Substituierte Imidazotriazinone

Publications (1)

Publication Number Publication Date
SV2002000776A true SV2002000776A (es) 2002-12-02

Family

ID=7668333

Family Applications (1)

Application Number Title Priority Date Filing Date
SV2001000776A SV2002000776A (es) 2000-12-21 2001-12-20 Nuevas imidazotriazinonas sustituidas ref.lea 34 985-sv

Country Status (15)

Country Link
US (1) US6573263B2 (es)
EP (1) EP1347978B1 (es)
JP (1) JP2004525098A (es)
AR (1) AR034423A1 (es)
AU (1) AU2002216087A1 (es)
CA (1) CA2431965A1 (es)
DE (2) DE10064105A1 (es)
DO (1) DOP2001000297A (es)
ES (1) ES2248228T3 (es)
GT (1) GT200100254A (es)
HN (1) HN2001000281A (es)
PE (1) PE20020756A1 (es)
SV (1) SV2002000776A (es)
UY (1) UY27080A1 (es)
WO (1) WO2002050078A1 (es)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7087605B2 (en) 2001-06-01 2006-08-08 Bayer Aktiengesellschaft 5-Ethyl-imidazotriazinones
GB0113342D0 (en) * 2001-06-01 2001-07-25 Bayer Ag Novel Heterocycles 1
CN100383124C (zh) * 2002-02-04 2008-04-23 霍夫曼-拉罗奇有限公司 作为npy拮抗剂的喹啉衍生物
CN1665791A (zh) * 2002-07-05 2005-09-07 霍夫曼-拉罗奇有限公司 喹唑啉衍生物
RU2324685C2 (ru) * 2002-08-07 2008-05-20 Ф.Хоффманн-Ля Рош Аг Производные тиазола, способ их получения и применение, фармацевтическая композиция, обладающая свойствами антагонистов рецепторов npy
JP2006219374A (ja) 2003-06-13 2006-08-24 Daiichi Asubio Pharma Co Ltd Pde7阻害作用を有するイミダゾトリアジノン誘導体
WO2013161913A1 (ja) 2012-04-25 2013-10-31 武田薬品工業株式会社 含窒素複素環化合物
US9527841B2 (en) 2012-07-13 2016-12-27 Takeda Pharmaceutical Company Limited Substituted pyrido[2,3-b]pyrazines as phosphodiesterase 2A inhibitors
WO2014142255A1 (ja) 2013-03-14 2014-09-18 武田薬品工業株式会社 複素環化合物
WO2015002230A1 (ja) 2013-07-03 2015-01-08 武田薬品工業株式会社 アミド化合物
JP6427491B2 (ja) 2013-07-03 2018-11-21 武田薬品工業株式会社 複素環化合物
WO2015096651A1 (en) 2013-12-23 2015-07-02 Merck Sharp & Dohme Corp. Pyrimidone carboxamide compounds as pde2 inhibitors
EP3091983B1 (en) * 2014-01-08 2019-10-02 Intra-Cellular Therapies, Inc. Pharmaceutical compositions comprising a pde-1 inhibitor and a pde-2 inhibitor
CN106459062A (zh) 2014-04-23 2017-02-22 达特神经科学(开曼)有限公司 作为PDE2抑制剂的取代的[1,2,4]三唑并[1,5‑a]嘧啶‑7‑基化合物
TWI568737B (zh) 2014-11-05 2017-02-01 達特神經科學(開曼)有限責任公司 作為pde2抑制劑之經取代的5-甲基-[1,2,4]三唑并[1,5-a]嘧啶-2-胺化合物
RU2709786C2 (ru) 2014-12-06 2019-12-20 Интра-Селлулар Терапиз, Инк. Органические соединения
CN107205993B (zh) 2014-12-06 2021-03-09 细胞内治疗公司 有机化合物
WO2016145614A1 (en) 2015-03-17 2016-09-22 Merck Sharp & Dohme Corp. Triazolyl pyrimidinone compounds as pde2 inhibitors
US10287269B2 (en) 2015-03-26 2019-05-14 Merck Sharp & Dohme Corp. Pyrazolyl pyrimidinone compounds as PDE2 inhibitors
EP3291817B1 (en) 2015-05-05 2019-10-02 Merck Sharp & Dohme Corp. Heteroaryl-pyrimidinone compounds as pde2 inhibitors
WO2016183741A1 (en) 2015-05-15 2016-11-24 Merck Sharp & Dohme Corp. Pyrimidinone amide compounds as pde2 inhibitors
WO2016191935A1 (en) 2015-05-29 2016-12-08 Merck Sharp & Dohme Corp. 6-alkyl dihydropyrazolopyrimidinone compounds as pde2 inhibitors
WO2016192083A1 (en) 2015-06-04 2016-12-08 Merck Sharp & Dohme Corp. Dihydropyrazolopyrimidinone compounds as pde2 inhibitors
WO2016209749A1 (en) 2015-06-25 2016-12-29 Merck Sharp & Dohme Corp. Substituted pyrazolo/imidazolo bicyclic compounds as pde2 inhibitors
WO2017000277A1 (en) 2015-07-01 2017-01-05 Merck Sharp & Dohme Corp. Substituted triazolo bicycliccompounds as pde2 inhibitors
WO2017000276A1 (en) 2015-07-01 2017-01-05 Merck Sharp & Dohme Corp. Bicyclic heterocyclic compounds as pde2 inhibitors
CN111447930A (zh) 2017-11-23 2020-07-24 奥斯陆大学医院公司 心动过速的治疗

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK109578A (da) 1977-03-25 1978-09-26 Allen & Hanburys Ltd Fremgangsmaade til fremstilling af heterocycliske forbindelser
DE19541264A1 (de) 1995-11-06 1997-05-07 Bayer Ag Purin-6-on-derivate
DE19709877A1 (de) 1997-03-11 1998-09-17 Bayer Ag 1,5-Dihydro-pyrazolo[3,4-d]-pyrimidinon-derivate
CA2309332C (en) * 1997-11-12 2002-12-03 Bayer Aktiengesellschaft 2-phenyl substituted imidazotriazinones as phosphodiesterase inhibitors
DE19827640A1 (de) * 1998-06-20 1999-12-23 Bayer Ag 7-Alkyl- und Cycloalkyl-substituierte Imidazotriazinone
DE19838705A1 (de) 1998-08-26 2000-03-02 Bayer Ag Neue Dihydro-(1,2,3)-triazolo-[4,5-d]pyrimidin-7-one

Also Published As

Publication number Publication date
ES2248228T3 (es) 2006-03-16
GT200100254A (es) 2002-08-19
EP1347978B1 (de) 2005-08-31
JP2004525098A (ja) 2004-08-19
DOP2001000297A (es) 2003-08-15
DE10064105A1 (de) 2002-06-27
US6573263B2 (en) 2003-06-03
HN2001000281A (es) 2003-02-04
UY27080A1 (es) 2002-07-31
EP1347978A1 (de) 2003-10-01
WO2002050078A1 (de) 2002-06-27
DE50107316D1 (de) 2005-10-06
AR034423A1 (es) 2004-02-25
AU2002216087A1 (en) 2002-07-01
CA2431965A1 (en) 2002-06-27
PE20020756A1 (es) 2002-10-02
US20020198377A1 (en) 2002-12-26

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