SV1999000059A - Compuestos farmaceuticos casa n.g. 1327 - Google Patents
Compuestos farmaceuticos casa n.g. 1327Info
- Publication number
- SV1999000059A SV1999000059A SV1999000059A SV1999000059A SV1999000059A SV 1999000059 A SV1999000059 A SV 1999000059A SV 1999000059 A SV1999000059 A SV 1999000059A SV 1999000059 A SV1999000059 A SV 1999000059A SV 1999000059 A SV1999000059 A SV 1999000059A
- Authority
- SV
- El Salvador
- Prior art keywords
- rent
- hydrogen
- alcoxi
- pharmaceutical compounds
- casa
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical class [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 5
- 229910052739 hydrogen Inorganic materials 0.000 abstract 5
- 239000001257 hydrogen Substances 0.000 abstract 5
- YCKRFDGAMUMZLT-UHFFFAOYSA-N Fluorine atom Chemical compound [F] YCKRFDGAMUMZLT-UHFFFAOYSA-N 0.000 abstract 1
- -1 HALO Chemical class 0.000 abstract 1
- JCXJVPUVTGWSNB-UHFFFAOYSA-N Nitrogen dioxide Chemical class O=[N]=O JCXJVPUVTGWSNB-UHFFFAOYSA-N 0.000 abstract 1
- CIUQDSCDWFSTQR-UHFFFAOYSA-N [C]1=CC=CC=C1 Chemical group [C]1=CC=CC=C1 CIUQDSCDWFSTQR-UHFFFAOYSA-N 0.000 abstract 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical group [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
- 229910052799 carbon Inorganic materials 0.000 abstract 1
- 150000001721 carbon Chemical class 0.000 abstract 1
- 229910052731 fluorine Inorganic materials 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 239000001301 oxygen Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/32—Alcohol-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/34—Tobacco-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Psychiatry (AREA)
- Addiction (AREA)
- Hospice & Palliative Care (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pain & Pain Management (AREA)
- Child & Adolescent Psychology (AREA)
- Obesity (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Gynecology & Obstetrics (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Otolaryngology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Indole Compounds (AREA)
Abstract
COMPUESTOS FARMACEUTICOS DE LA FORMULA, VER FORMULA, EN LA CUAL N ES DE 1 A 6, M ES 1 O 2 Y P ES 1 O 2. R1 Y R2 SON CADA UNA HIDROGENO, ALQUIL C1-4, ALCOXI C1,C4, ALQUIL C1-4-HO, ALCOXI C1-4-ALQUIL C1-4, ALQUILTIO C1-4, HALO OPCIONALMENTE FENILO SUBSTITUIDO, OPCIONALMENTE ALQUIL C1-4-FENILO SUBSTITUIDO, O R1 Y R2 JUNTOS CON EL ATOMO DE CARBONO AL CUAL ESTAN UNIDOS FORMAN UN GRUPO CICLOALQUILO C3-6, >C=0, C=NOR', EN DONDE R' ES HIDROGENO O ALQUIL C1-4.R3, R4 Y R5 SON CADA UNA HIDROGENO, HALO, NITRO, ALQUIL C1-4, ALCOXI C1-4, ALQUIL C1-4-CO-, EN DONDE M ES O, 1 O 2 R'R''N-SO2-, -COOR', -CONR'R'', -NR'R'', -N(OR')COOR'', -COR', -NHSO2R', EN DONDE R' Y R'' SON CADA UNA HIDROGENO O ALQUIL C1-4.R6 Y R7 SON CADA UNA HIDROGENO A ALQUIL C1-4.X ES OXIGENO O SULFUROLA LINEA PUNTEADA REPRESENTA UN DOBLE ENLACE OPCIONAL, Y EL ATOMO DE FLUORINA ESTA UNIDO EN LA POSICION 6- O T-, Y SALES DEL MISMO.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9810886.3A GB9810886D0 (en) | 1998-05-13 | 1998-05-13 | Pharmaceutical compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SV1999000059A true SV1999000059A (es) | 2000-07-04 |
Family
ID=10832426
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SV1999000059A SV1999000059A (es) | 1998-05-13 | 1999-05-11 | Compuestos farmaceuticos casa n.g. 1327 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US6166040A (es) |
| EP (1) | EP0963983A1 (es) |
| JP (1) | JP2002514642A (es) |
| AR (1) | AR018859A1 (es) |
| AU (1) | AU3838499A (es) |
| CA (1) | CA2330796A1 (es) |
| CO (1) | CO5031250A1 (es) |
| GB (1) | GB9810886D0 (es) |
| PE (1) | PE20000467A1 (es) |
| SV (1) | SV1999000059A (es) |
| WO (1) | WO1999058525A1 (es) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9825413D0 (en) * | 1998-11-19 | 1999-01-13 | Lilly Co Eli | Pharmaceutical compounds |
| US6844338B2 (en) | 2000-05-18 | 2005-01-18 | Eli Lilly And Company | Piperidyindoles as serotonin receptor ligands |
| GB2362381A (en) * | 2000-05-18 | 2001-11-21 | Lilly Co Eli | Pharmaceutically active indolyl-piperidines |
| AR028685A1 (es) | 2000-06-14 | 2003-05-21 | Lundbeck & Co As H | Derivados de indol |
| SI1294710T1 (en) * | 2000-06-14 | 2005-10-31 | H. Lundbeck A/S | Indole derivatives useful for the treatment of cns disorders |
| GB2370270A (en) * | 2000-12-20 | 2002-06-26 | Lilly Co Eli | Pharmaceutical compounds |
| ES2230484T3 (es) * | 2001-03-14 | 2005-05-01 | Wyeth | Derivados antidepresivos azaheterociclimeticos de 2,3-dihidro-1,4-dioxino (2,3-f) quinolina. |
| US6777437B2 (en) | 2001-03-29 | 2004-08-17 | Bristol-Myers Squibb Company | Cyclopropylindole derivatives as selective serotonin reuptake inhibitors |
| US6861434B2 (en) * | 2001-04-26 | 2005-03-01 | Wyeth | Antipsychotic aminomethyl derivatives of 1,3,7,8-tetrahydro-6,9-dioxa-1,3-diaza-cyclopenta[a]-naphthalen-2-one |
| US6906206B2 (en) | 2001-04-30 | 2005-06-14 | Wyeth | Antidepressant azaheterocyclylmethyl derivatives of 1,4,5-trioxa-phenanthrene |
| US6555560B2 (en) | 2001-04-30 | 2003-04-29 | Wyeth | Antidepressant azaheterocyclylmethyl derivatives of 1,4,5-trioxa-phenanthrene |
| CN100352820C (zh) * | 2002-09-12 | 2007-12-05 | 惠氏公司 | 抗抑郁的杂环稠合的苯并二噁烷的氮杂环甲基衍生物 |
| US7135479B2 (en) | 2002-09-12 | 2006-11-14 | Wyeth | Antidepressant azaheterocyclylmethyl derivatives of heterocycle-fused benzodioxans |
| DE10337184A1 (de) | 2003-08-13 | 2005-03-10 | Gruenenthal Gmbh | Substituierte 3-Pyrrolidin-Indol-Derivate |
| WO2006023852A2 (en) * | 2004-08-19 | 2006-03-02 | Vertex Pharmaceuticals, Incorporated | Modulators of muscarinic receptors |
| US7786141B2 (en) * | 2004-08-19 | 2010-08-31 | Vertex Pharmaceuticals Incorporated | Dihydrospiroindene modulators of muscarinic receptors |
| JP2008521825A (ja) * | 2004-11-29 | 2008-06-26 | バーテックス ファーマシューティカルズ インコーポレイテッド | ムスカリン受容体のモジュレーター |
| CN101374519A (zh) * | 2005-12-22 | 2009-02-25 | 弗特克斯药品有限公司 | 毒蕈碱性受体调节剂 |
| CN101426499A (zh) | 2006-02-22 | 2009-05-06 | 弗特克斯药品有限公司 | 毒蕈碱受体调节剂 |
| CA2642649A1 (en) * | 2006-02-22 | 2007-09-07 | Vertex Pharmaceuticals Incorporated | Modulators of muscarinic receptors |
| CN101500565A (zh) * | 2006-06-29 | 2009-08-05 | 弗特克斯药品有限公司 | 毒蕈碱性受体的调节剂 |
| CN101553231A (zh) * | 2006-08-15 | 2009-10-07 | 弗特克斯药品有限公司 | 毒蕈碱受体调节剂 |
| EP2051715A2 (en) * | 2006-08-18 | 2009-04-29 | Vertex Pharmceuticals Incorporated | Modulators of muscarinic receptors |
| CA2700724A1 (en) * | 2007-10-03 | 2009-04-09 | Vertex Pharmaceuticals Incorporated | Modulators of muscarinic receptors |
| MX2023006652A (es) * | 2020-12-07 | 2023-09-21 | Mindset Pharma Inc | Derivados de amina-indol-3-ciclica como agentes serotonergicos para el tratamiento de trastornos del snc. |
| KR102509625B1 (ko) * | 2022-03-25 | 2023-03-14 | 주식회사 메드팩토 | TGF-β 저해제의 합성에 유용한 중간체 및 이를 이용한 TGF-β 저해제 제조방법 |
| WO2025021120A1 (zh) * | 2023-07-24 | 2025-01-30 | 上海翊石医药科技有限公司 | 一类5-ht2a受体激动剂及其制备方法和应用 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3981881A (en) * | 1975-08-14 | 1976-09-21 | E. R. Squibb & Sons, Inc. | 2-[(4-Phenyl-tetrahydropyridinyl)alkyl]-1H-isoindole-1,3(2H)-diones |
| JP2860688B2 (ja) * | 1990-03-14 | 1999-02-24 | 第一製薬株式会社 | インドール誘導体 |
| FR2675801A1 (fr) * | 1991-04-24 | 1992-10-30 | Rhone Poulenc Rorer Sa | Piperidines, leur preparation et les medicaments les contenant. |
| SE9103752D0 (sv) * | 1991-12-18 | 1991-12-18 | Astra Ab | New compounds |
| US5521196A (en) * | 1994-10-05 | 1996-05-28 | Eli Lilly And Company | 5-HT1F agonists for the treatment of migraine |
| TW421649B (en) * | 1995-01-31 | 2001-02-11 | Janssen Pharmaceutica Nv | 4-(1H-indol-1yl)-1-piperidinyl derivatives |
| GB2308362A (en) * | 1995-12-19 | 1997-06-25 | Lilly Industries Ltd | Pharmaceutical indole derivatives |
-
1998
- 1998-05-13 GB GBGB9810886.3A patent/GB9810886D0/en not_active Ceased
-
1999
- 1999-05-10 PE PE1999000381A patent/PE20000467A1/es not_active Application Discontinuation
- 1999-05-11 SV SV1999000059A patent/SV1999000059A/es unknown
- 1999-05-11 US US09/309,420 patent/US6166040A/en not_active Expired - Fee Related
- 1999-05-11 AR ARP990102204A patent/AR018859A1/es unknown
- 1999-05-11 EP EP99303663A patent/EP0963983A1/en not_active Withdrawn
- 1999-05-11 WO PCT/GB1999/001474 patent/WO1999058525A1/en not_active Ceased
- 1999-05-11 JP JP2000548329A patent/JP2002514642A/ja active Pending
- 1999-05-11 CA CA002330796A patent/CA2330796A1/en not_active Abandoned
- 1999-05-11 AU AU38384/99A patent/AU3838499A/en not_active Abandoned
- 1999-05-11 CO CO99029124A patent/CO5031250A1/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CO5031250A1 (es) | 2001-04-27 |
| PE20000467A1 (es) | 2000-06-05 |
| AR018859A1 (es) | 2001-12-12 |
| WO1999058525A1 (en) | 1999-11-18 |
| US6166040A (en) | 2000-12-26 |
| JP2002514642A (ja) | 2002-05-21 |
| GB9810886D0 (en) | 1998-07-22 |
| CA2330796A1 (en) | 1999-11-18 |
| AU3838499A (en) | 1999-11-29 |
| EP0963983A1 (en) | 1999-12-15 |
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