SU476747A3 - The method of obtaining choline chloride - Google Patents
The method of obtaining choline chlorideInfo
- Publication number
- SU476747A3 SU476747A3 SU1887169A SU1887169A SU476747A3 SU 476747 A3 SU476747 A3 SU 476747A3 SU 1887169 A SU1887169 A SU 1887169A SU 1887169 A SU1887169 A SU 1887169A SU 476747 A3 SU476747 A3 SU 476747A3
- Authority
- SU
- USSR - Soviet Union
- Prior art keywords
- choline chloride
- obtaining
- obtaining choline
- chloride
- flowability
- Prior art date
Links
- 239000001763 2-hydroxyethyl(trimethyl)azanium Substances 0.000 title description 3
- 235000019743 Choline chloride Nutrition 0.000 title description 3
- 229960003178 choline chloride Drugs 0.000 title description 3
- SGMZJAMFUVOLNK-UHFFFAOYSA-M choline chloride Chemical compound [Cl-].C[N+](C)(C)CCO SGMZJAMFUVOLNK-UHFFFAOYSA-M 0.000 title description 3
- 238000000034 method Methods 0.000 title description 2
- 235000012239 silicon dioxide Nutrition 0.000 description 2
- 238000010521 absorption reaction Methods 0.000 description 1
- 239000007864 aqueous solution Substances 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 230000002209 hydrophobic effect Effects 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- RMAQACBXLXPBSY-UHFFFAOYSA-N silicic acid Chemical compound O[Si](O)(O)O RMAQACBXLXPBSY-UHFFFAOYSA-N 0.000 description 1
- 125000005624 silicic acid group Chemical class 0.000 description 1
- 238000005245 sintering Methods 0.000 description 1
- 238000001694 spray drying Methods 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2/00—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic
- B01J2/30—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic using agents to prevent the granules sticking together; Rendering particulate materials free flowing in general, e.g. making them hydrophobic
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Treating Waste Gases (AREA)
- Gas Separation By Absorption (AREA)
- Silicon Compounds (AREA)
- Medicinal Preparation (AREA)
Description
открытом воздухе (водопоглощение до 20%) в течение года сыпучесть не измен етс .open air (water absorption up to 20%) during the year flowability does not change.
Предмет изобретеии Subject of invention
Способ получени холинхлорида смешиванием концентрированного водного раствора холинхлорида со вспомогательным средством , придающим сыпучесть, на основеThe method of obtaining choline chloride by mixing a concentrated aqueous solution of choline chloride with an auxiliary flow agent, based on
кремневой кислоты с иоследуюп 1.еи распылительной сушкой, отличающийс тем, что, с нелыо иредотвращеии спекани продукта и улучшени его свойств, в качестве средства , придающего сыпучесть, используюг смесь гидрофильной и гидрофобной кремневой кислот, вз тых по крайней мере в количестве 2% и 3% соответственно, счита иаsilicic acid and the subsequent 1. and spray drying, characterized in that, with the lack of prevention of sintering of the product and improvement of its properties, as a means of giving flowability, using a mixture of hydrophilic and hydrophobic silicic acids, taken at least in the amount of 2% and 3%, respectively,
ХОЛННХЛОрИхЗ,.HOLNHLORIHZ ,.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE2209477A DE2209477A1 (en) | 1972-02-29 | 1972-02-29 | PROCESS FOR PRODUCING SOLID, FREE-FLOWING CHOLINE CHLORIDE |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SU476747A3 true SU476747A3 (en) | 1975-07-05 |
Family
ID=5837392
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SU1887169A SU476747A3 (en) | 1972-02-29 | 1973-02-27 | The method of obtaining choline chloride |
Country Status (12)
| Country | Link |
|---|---|
| JP (1) | JPS4898013A (en) |
| AT (1) | AT335405B (en) |
| BE (1) | BE795866A (en) |
| DD (1) | DD105206A5 (en) |
| DE (1) | DE2209477A1 (en) |
| FR (1) | FR2174170B1 (en) |
| GB (1) | GB1412204A (en) |
| HU (1) | HU165009B (en) |
| IL (1) | IL41620A (en) |
| IT (1) | IT989015B (en) |
| NL (1) | NL7302587A (en) |
| SU (1) | SU476747A3 (en) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3409063A1 (en) * | 1984-03-13 | 1985-09-19 | Basf Ag, 6700 Ludwigshafen | METHOD FOR PRODUCING FLOWABLE CHOLIN CHLORIDE-SILICONE POWDER |
| DE3623922A1 (en) * | 1986-07-16 | 1988-01-21 | Basf Ag | METHOD FOR PRODUCING A DUST-FREE, FREE-FLOWING CHOLINE CHLORIDE POWDER |
| DE4218768A1 (en) * | 1992-06-06 | 1993-12-09 | Basf Ag | Process for the preparation of powders containing choline chloride, these powders and their use |
| US5766668A (en) * | 1995-03-27 | 1998-06-16 | Chinook Group, Inc. | Method for synthesizing chloride based feed precursor and product resulting therefrom |
| DE19825687A1 (en) * | 1998-06-09 | 1999-12-16 | Degussa | Active ingredient concentrate |
| US9339459B2 (en) | 2003-04-24 | 2016-05-17 | Nektar Therapeutics | Particulate materials |
| US8110674B2 (en) | 2003-03-07 | 2012-02-07 | Alnylam Pharmaceuticals, Inc. | Therapeutic compositions |
| EP1625138A4 (en) | 2003-04-17 | 2010-06-23 | Alnylam Pharmaceuticals Inc | Protected monomers |
| EP2660322A3 (en) | 2003-04-17 | 2013-11-13 | Alnylam Pharmaceuticals Inc. | Modified iRNA agents |
| JP5635412B2 (en) | 2007-12-04 | 2014-12-03 | アルニラム ファーマスーティカルズ インコーポレイテッドＡｌｎｙｌａｍ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ， Ｉｎｃ． | Targeted lipid |
| EP2274425A2 (en) | 2008-04-11 | 2011-01-19 | Alnylam Pharmaceuticals Inc. | Site-specific delivery of nucleic acids by combining targeting ligands with endosomolytic components |
| EP2206440A1 (en) | 2008-12-24 | 2010-07-14 | Taminco | Process for preparing a free-flowing powder containing a deliquescent quaternary ammonium compound |
| WO2011109427A2 (en) | 2010-03-01 | 2011-09-09 | Alnylam Pharmaceuticals, Inc. | Improving the biological activity of sirna through modulation of its thermodynamic profile |
| WO2016057693A1 (en) | 2014-10-10 | 2016-04-14 | Alnylam Pharmaceuticals, Inc. | Methods and compositions for inhalation delivery of conjugated oligonucleotide |
| CN105876164A (en) * | 2016-06-17 | 2016-08-24 | 山东奥克特化工有限公司 | Preparation method and preparation device of choline chloride powder |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1642998B2 (en) * | 1967-03-23 | 1973-05-17 | PROCESS FOR PREVENTING AGGLOMERATION OF FINE PARTICLE, 1POWDER-FABRIC MATERIALS |
-
0
- BE BE795866D patent/BE795866A/en unknown
-
1972
- 1972-02-29 DE DE2209477A patent/DE2209477A1/en active Pending
-
1973
- 1973-02-15 IT IT20455/73A patent/IT989015B/en active
- 1973-02-23 NL NL7302587A patent/NL7302587A/xx unknown
- 1973-02-23 HU HUBA2878A patent/HU165009B/hu unknown
- 1973-02-26 IL IL41620A patent/IL41620A/en unknown
- 1973-02-27 SU SU1887169A patent/SU476747A3/en active
- 1973-02-27 DD DD169081A patent/DD105206A5/xx unknown
- 1973-02-27 GB GB948473A patent/GB1412204A/en not_active Expired
- 1973-02-27 JP JP48022764A patent/JPS4898013A/ja active Pending
- 1973-02-28 AT AT176273A patent/AT335405B/en not_active IP Right Cessation
- 1973-02-28 FR FR7307139A patent/FR2174170B1/fr not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| IL41620A (en) | 1975-10-15 |
| HU165009B (en) | 1974-06-28 |
| AT335405B (en) | 1977-03-10 |
| IL41620A0 (en) | 1973-04-30 |
| NL7302587A (en) | 1973-08-31 |
| DE2209477A1 (en) | 1973-09-06 |
| FR2174170B1 (en) | 1977-12-30 |
| ATA176273A (en) | 1976-07-15 |
| GB1412204A (en) | 1975-10-29 |
| FR2174170A1 (en) | 1973-10-12 |
| IT989015B (en) | 1975-05-20 |
| JPS4898013A (en) | 1973-12-13 |
| DD105206A5 (en) | 1974-04-12 |
| BE795866A (en) | 1973-08-23 |
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