SU1090719A1 - Method for determining in vitro threshold concentration of membranetoxic effect of chemicals - Google Patents
Method for determining in vitro threshold concentration of membranetoxic effect of chemicals Download PDFInfo
- Publication number
- SU1090719A1 SU1090719A1 SU823499924A SU3499924A SU1090719A1 SU 1090719 A1 SU1090719 A1 SU 1090719A1 SU 823499924 A SU823499924 A SU 823499924A SU 3499924 A SU3499924 A SU 3499924A SU 1090719 A1 SU1090719 A1 SU 1090719A1
- Authority
- SU
- USSR - Soviet Union
- Prior art keywords
- chemicals
- vitro
- threshold concentration
- membranetoxic
- determining
- Prior art date
Links
- 238000000034 method Methods 0.000 title claims abstract 7
- 239000000126 substance Substances 0.000 title claims abstract 5
- 238000000338 in vitro Methods 0.000 title claims abstract 3
- 230000029918 bioluminescence Effects 0.000 claims abstract 2
- 238000005415 bioluminescence Methods 0.000 claims abstract 2
- 210000004027 cell Anatomy 0.000 claims abstract 2
- 210000003743 erythrocyte Anatomy 0.000 claims abstract 2
Landscapes
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Abstract
СПОСОБ ОПРЕДЕЛЕНИЯ IN. IVITRO ПОРОГОВОЙ КОНЦЕНТРАЦИИ МЕМБРАНОТОКСИЧЕСКОГО ДЕЙСТВИЯ ХИМИЧЕСКИХ ВЕЩЕСТВ с регистрацией биолюминесценции , отличающийс тем, что, с целью повышени точнойти и упрощени способа, эритроциты человека инкубируют in vitro с химическими веществами концентраций от М до 1 М и регистрируют выход АТФ из клеток хемилюминесцентным методом.METHOD OF IDENTIFICATION IN. IVITRO threshold concentration MEMBRANOTOKSICHESKOGO OF CHEMICALS with registration bioluminescence, characterized in that, in order to increase tochnoyti and simplify the process, human erythrocytes incubated in vitro with chemicals concentrations from M to 1 M and recorded yield of ATP from cells chemiluminescent method.
Description
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Claims (1)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SU823499924A SU1090719A1 (en) | 1982-10-14 | 1982-10-14 | Method for determining in vitro threshold concentration of membranetoxic effect of chemicals |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SU823499924A SU1090719A1 (en) | 1982-10-14 | 1982-10-14 | Method for determining in vitro threshold concentration of membranetoxic effect of chemicals |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SU1090719A1 true SU1090719A1 (en) | 1984-05-07 |
Family
ID=21031949
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SU823499924A SU1090719A1 (en) | 1982-10-14 | 1982-10-14 | Method for determining in vitro threshold concentration of membranetoxic effect of chemicals |
Country Status (1)
| Country | Link |
|---|---|
| SU (1) | SU1090719A1 (en) |
-
1982
- 1982-10-14 SU SU823499924A patent/SU1090719A1/en active
Non-Patent Citations (1)
| Title |
|---|
| 1. Методил установлени допустимых уровней воздействи профессиональных вредностей. Доклад Комитета экспертов Всемирной Организации . Здравоохранени с участием МОТ, Сери технических докладов 601, Женева, 1978. 2. Патент US 4246340, кл. С 12Q1/66, 20.01.81 (прототип). * |
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