[go: up one dir, main page]

SMT201600055B - Composizione farmaceutica per il trattamento o la prevenzione del glaucoma - Google Patents

Composizione farmaceutica per il trattamento o la prevenzione del glaucoma

Info

Publication number
SMT201600055B
SMT201600055B SM201600055T SM201600055T SMT201600055B SM T201600055 B SMT201600055 B SM T201600055B SM 201600055 T SM201600055 T SM 201600055T SM 201600055 T SM201600055 T SM 201600055T SM T201600055 B SMT201600055 B SM T201600055B
Authority
SM
San Marino
Prior art keywords
glaucoma
prevention
treatment
pharmaceutical composition
pharmaceutical
Prior art date
Application number
SM201600055T
Other languages
English (en)
Italian (it)
Inventor
Masahiko Hagihara
Kenji Yoneda
Eiji Okanari
Manabu Shigetomi
Original Assignee
Ube Industries
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ube Industries filed Critical Ube Industries
Publication of SMT201600055B publication Critical patent/SMT201600055B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/83—Thioacids; Thioesters; Thioamides; Thioimides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/443—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with oxygen as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/444—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/50—Pyridazines; Hydrogenated pyridazines
    • A61K31/501—Pyridazines; Hydrogenated pyridazines not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
SM201600055T 2009-03-30 2016-02-24 Composizione farmaceutica per il trattamento o la prevenzione del glaucoma SMT201600055B (it)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2009082725 2009-03-30
PCT/JP2010/055719 WO2010113957A1 (fr) 2009-03-30 2010-03-30 Composition pharmaceutique pour la prévention ou le traitement du glaucome

Publications (1)

Publication Number Publication Date
SMT201600055B true SMT201600055B (it) 2016-04-29

Family

ID=42828246

Family Applications (1)

Application Number Title Priority Date Filing Date
SM201600055T SMT201600055B (it) 2009-03-30 2016-02-24 Composizione farmaceutica per il trattamento o la prevenzione del glaucoma

Country Status (17)

Country Link
US (1) US8685986B2 (fr)
EP (1) EP2415763B1 (fr)
JP (2) JP5300033B2 (fr)
KR (1) KR101681347B1 (fr)
CN (1) CN102448940B (fr)
AU (1) AU2010231630B2 (fr)
CA (1) CA2757291C (fr)
CY (1) CY1117193T1 (fr)
DK (1) DK2415763T3 (fr)
ES (1) ES2564010T3 (fr)
HR (1) HRP20160104T1 (fr)
HU (1) HUE026742T2 (fr)
PL (1) PL2415763T3 (fr)
PT (1) PT2415763E (fr)
SI (1) SI2415763T1 (fr)
SM (1) SMT201600055B (fr)
WO (1) WO2010113957A1 (fr)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2718813T3 (es) * 2008-03-12 2019-07-04 Ube Industries Compuesto de ácido piridilaminoacético
HRP20160104T1 (hr) 2009-03-30 2016-03-25 Ube Industries Farmaceutski pripravak za liječenje ili prevenciju glaukoma
US20120226036A1 (en) * 2009-09-11 2012-09-06 Ube Industries, Ltd. Substituted carbonyl compound
JP2011057633A (ja) * 2009-09-11 2011-03-24 Ube Industries Ltd ピリジルアミノ酢酸化合物を含有する医薬
US20120259123A1 (en) 2009-12-25 2012-10-11 Ube Industries, Ltd. Aminopyridine compound
US9339496B2 (en) * 2012-07-13 2016-05-17 Santen Pharmaceutical Co., Ltd. Composition for treating or preventing glaucoma comprising a sulfonamide compound, and a beta-receptor antagonist
WO2014010654A2 (fr) * 2012-07-13 2014-01-16 参天製薬株式会社 Combinaison de composés de sulfonamide
US9676720B2 (en) 2013-03-28 2017-06-13 Ube Industries, Ltd. Substituted biaryl compound
KR102458180B1 (ko) * 2014-01-10 2022-10-21 산텐 세이야꾸 가부시키가이샤 피리딜아미노아세트산 화합물과 폴리옥시에틸렌 피마자유를 함유하는 의약 조성물
JP6441087B2 (ja) 2014-01-10 2018-12-19 参天製薬株式会社 ピリジルアミノ酢酸化合物含有医薬組成物
EP3750541A1 (fr) * 2014-01-10 2020-12-16 Santen Pharmaceutical Co., Ltd Préparation pharmaceutique contenant un composé d'acide pyridylaminoacétique
US10774072B2 (en) 2014-06-10 2020-09-15 Ube Industries, Ltd. Crystal of N-substituted sulfonamide compound
EP3156395B1 (fr) * 2014-06-10 2019-01-09 UBE Industries, Ltd. Procédé de fabrication d'un composé de sulfonamide hétéroaromatique
JP6572891B2 (ja) * 2014-06-10 2019-09-11 宇部興産株式会社 Ｎ−置換スルホンアミド化合物およびその製造方法
JP2017206445A (ja) * 2014-09-26 2017-11-24 宇部興産株式会社 呼吸器疾患の治療及び／又は予防のための医薬組成物
CA2991015A1 (fr) * 2015-07-01 2017-01-05 Santen Pharmaceutical Co., Ltd. Preparation de depot contenant un ester d'acide citrique
TWI794140B (zh) * 2015-07-09 2023-03-01 日商參天製藥股份有限公司 含有吡啶基胺基乙酸化合物之預防及/或治療劑
WO2019065838A1 (fr) 2017-09-29 2019-04-04 参天製薬株式会社 Médicament contenant un composé d'acide pyridylaminoacétique
EP3730143A4 (fr) 2017-12-21 2021-08-18 Santen Pharmaceutical Co., Ltd. Association de l'omidénépag
EP4338751B1 (fr) 2017-12-21 2025-09-03 Santen Pharmaceutical Co., Ltd. Combinaison de sepetaprost et de netarsudil pour l'utilisation dans la prophylaxie ou le traitement du glaucome ou de l'hypertension oculaire
US11666563B2 (en) * 2017-12-28 2023-06-06 Santen Pharmaceutical Co., Ltd. Pharmaceutical preparation containing pyridyl aminoacetic acid compound
KR20220089106A (ko) 2020-12-21 2022-06-28 이성규 도르졸라마이드 또는 폴리소르베이트80을 유효성분으로 포함하는 점안용 조성물
CN118084895B (zh) * 2024-02-28 2025-09-05 中国药科大学 一种一氧化氮供体型Omidenepag衍生物及其制备方法和应用

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW523506B (en) 1996-12-18 2003-03-11 Ono Pharmaceutical Co Sulfonamide or carbamide derivatives and drugs containing the same as active ingredients
UA59384C2 (uk) 1996-12-20 2003-09-15 Пфайзер, Інк. Похідні сульфонамідів та амідів як агоністи простагландину, фармацевтична композиція та способи лікування на їх основі
UA67754C2 (uk) 1997-10-10 2004-07-15 Пфайзер, Інк. Агоністи простагландину, фармацевтична композиція на їх основі (варіанти), спосіб нарощення та збереження кісткової маси у хребетних та спосіб лікування (варіанти)
AU745425B2 (en) 1998-01-27 2002-03-21 Aventis Pharmaceuticals Inc. Substituted oxoazaheterocyclyl factor Xa inhibitors
AU2001290250A1 (en) 2000-09-21 2002-04-02 Ono Pharmaceutical Co. Ltd. Ep4 receptor agonists containing 8-azaprostaglandin derivatives as the active ingredient
MXPA04001253A (es) 2001-08-09 2004-06-03 Ono Pharmaceutical Co Derivados de acidos carboxilicos y agente farmaceutico que comprende los mismos como ingrediente activo.
AU2001297521B2 (en) 2001-10-26 2007-10-04 Allergan, Inc. Co-cycloalkyl 17-heteroaryl prostaglandin E2 analogs as EP2-receptor agonists
KR20040077884A (ko) 2002-01-31 2004-09-07 화이자 프로덕츠 인코포레이티드 （3-｛〔（4-3급-뷰틸-벤질）-（피리딘-3-설폰일）-아미노〕-메틸｝-페녹시）-아세트산의 대사산물
AU2003211574A1 (en) 2002-03-05 2003-09-16 Ono Pharmaceutical Co., Ltd. 8-azaprostaglandin derivative compounds and drugs containing the compounds as the active ingredient
US20070000939A1 (en) 2002-10-29 2007-01-04 Vasilios Vasiadis Device for handling and orientating pills or tablets in a precise manner
EP1601351A1 (fr) 2003-03-04 2005-12-07 Pfizer Products Inc. Utilisation d'agonistes selectifs du recepteur ep2 dans un traitement medical
GB0329620D0 (en) 2003-12-22 2004-01-28 Pharmagene Lab Ltd EP2 receptor agonists
JP2007186424A (ja) 2004-11-26 2007-07-26 Ono Pharmaceut Co Ltd 気管支拡張剤
WO2005072743A1 (fr) 2004-01-30 2005-08-11 Ono Pharmaceutical Co., Ltd. Broncho-dilatateurs
WO2005077912A1 (fr) 2004-02-12 2005-08-25 Mitsubishi Pharma Corporation Composé indazole et utilisation pharmaceutique de celui-ci
EP1593671A1 (fr) 2004-03-05 2005-11-09 Graffinity Pharmaceuticals AG Inhibiteurs de la DPP-IV
US20060135773A1 (en) 2004-06-17 2006-06-22 Semple Joseph E Trisubstituted nitrogen modulators of tyrosine phosphatases
GB0415320D0 (en) 2004-07-08 2004-08-11 Astrazeneca Ab Novel compounds
RU2007125622A (ru) 2005-01-14 2009-02-20 Ф. Хоффманн-Ля Рош Аг (Ch) Производные тиазол-4-карбоксамида в качестве антагонистов mclur5
US7829585B2 (en) 2005-03-30 2010-11-09 Eisai R&D Management Co., Ltd. Antifungal agent containing pyridine derivative
AU2006275263A1 (en) 2005-08-03 2007-02-08 Merck Frosst Canada Ltd EP4 receptor agonist, compositions and methods thereof
JP2009505973A (ja) 2005-08-09 2009-02-12 アステランド ユーケイ リミテッド Ｅｐ２受容体アゴニスト
US7696235B2 (en) 2005-08-29 2010-04-13 Allergan, Inc. EP2 receptor agonists for treating glaucoma
EA200970067A1 (ru) 2006-07-28 2009-08-28 Пфайзер Продактс Инк. Агонисты ep2
FI123744B (fi) * 2006-09-06 2013-10-15 Sandvik Mining & Constr Oy Menetelmä kallion poraamiseksi
ES2718813T3 (es) * 2008-03-12 2019-07-04 Ube Industries Compuesto de ácido piridilaminoacético
HRP20160104T1 (hr) 2009-03-30 2016-03-25 Ube Industries Farmaceutski pripravak za liječenje ili prevenciju glaukoma

Also Published As

Publication number Publication date
EP2415763A1 (fr) 2012-02-08
US20120190852A1 (en) 2012-07-26
SI2415763T1 (sl) 2016-05-31
JP5300033B2 (ja) 2013-09-25
EP2415763A4 (fr) 2012-08-15
AU2010231630A1 (en) 2011-11-10
KR101681347B1 (ko) 2016-11-30
JPWO2010113957A1 (ja) 2012-10-11
HUE026742T2 (en) 2016-07-28
CN102448940A (zh) 2012-05-09
AU2010231630B2 (en) 2015-02-12
PL2415763T3 (pl) 2016-05-31
HRP20160104T1 (hr) 2016-03-25
HK1170490A1 (zh) 2013-03-01
DK2415763T3 (en) 2016-03-07
WO2010113957A1 (fr) 2010-10-07
CA2757291C (fr) 2017-05-23
EP2415763B1 (fr) 2016-01-27
CY1117193T1 (el) 2017-04-05
US8685986B2 (en) 2014-04-01
CA2757291A1 (fr) 2010-10-07
PT2415763E (pt) 2016-03-30
KR20120003475A (ko) 2012-01-10
JP5556924B2 (ja) 2014-07-23
JP2013151548A (ja) 2013-08-08
ES2564010T3 (es) 2016-03-17
CN102448940B (zh) 2015-10-21

Similar Documents

Publication Publication Date Title
SMT201600055B (it) Composizione farmaceutica per il trattamento o la prevenzione del glaucoma
BRPI1012116A2 (pt) composição farmacêutica para o tratamento de doenças cardíacas
PL2512515T3 (pl) Kompozycja farmaceutyczna do leczenia zespołu suchego oka
IL216800A (en) Preparation for the treatment of dry eye syndrome
HUE061548T2 (hu) Komplementtel összefüggõ rendellenességek kezelésére szolgáló eljárások és készítmények
EP2512240A4 (fr) Méthodes et compositions de traitement et de prévention des céphalées trigémino-autonomiques, des migraines et des pathologies vasculaires
IL224215A (en) An integrated drug for the treatment of functional diseases or conditions of the gastrointestinal system
HUE045367T2 (hu) Kombinált terápia diabétesz kezelésére
SMT201500189T1 (it) Ligandi sigma per la prevenzione o il trattamento del dolore indotto da chmioterapia
PL2429507T3 (pl) Kompozycja farmaceutyczna wolna od fosforanów do leczenia jaskry
SMT201900015T1 (it) Medicamento per uso topico a base di acido ialuronico solfatato per il trattamento dei coaguli di fibrina e dei trombi
PL2582366T3 (pl) Kombinacja farmaceutyczna do leczenia bólu
ZA201200944B (en) Pharmaceutical compositions for the treatment of cancer and other diseases or disorders
BRPI0917440A2 (pt) composições farmacêuticas oftálmicas para o tratamento de patologias neoangiogênicas do olho
GB0906159D0 (en) Drug combination for the treatment of proteostatic diseases
EP2500020A4 (fr) Agent de traitement ou de prévention du diabète
IT1397838B1 (it) Composizione per la cura delle piante
SMT201600126B (it) Solfonammidi per la prevenzione del diabete
IL200753A (en) Pharmaceutical preparation containing ib – meca for the treatment of psoriasis
HU0900231D0 (en) Compositions for the treatment of allergic disorders
SMT201600268B (it) Composizione per il trattamento delle neuropatie
DK2361627T3 (da) Sammensætning til forebyggelse eller behandling af øjensygdomme
IL219050A0 (en) Pharmaceutical composition for the treatment of bladder disorders
PT2344166E (pt) Composição farmacêutica para o tratamento da irritação gastrointestinal
FI20075971L (fi) Koostumus steriilin tulehduksen hoitoon