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SMT201300045B - Processi per la preparazione di composti di amminosolfone - Google Patents

Processi per la preparazione di composti di amminosolfone

Info

Publication number
SMT201300045B
SMT201300045B SM201300045T SM201300045T SMT201300045B SM T201300045 B SMT201300045 B SM T201300045B SM 201300045 T SM201300045 T SM 201300045T SM 201300045 T SM201300045 T SM 201300045T SM T201300045 B SMT201300045 B SM T201300045B
Authority
SM
San Marino
Prior art keywords
processes
preparation
aminosulfone compounds
aminosulfone
compounds
Prior art date
Application number
SM201300045T
Other languages
English (en)
Inventor
Manohar T Saindane
Chuansheng Ge
Original Assignee
Celgene Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Celgene Corp filed Critical Celgene Corp
Publication of SMT201300045B publication Critical patent/SMT201300045B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C315/00—Preparation of sulfones; Preparation of sulfoxides
    • C07C315/04—Preparation of sulfones; Preparation of sulfoxides by reactions not involving the formation of sulfone or sulfoxide groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
SM201300045T 2008-09-10 2013-04-19 Processi per la preparazione di composti di amminosolfone SMT201300045B (it)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US9590208P 2008-09-10 2008-09-10
PCT/US2009/005055 WO2010030345A2 (en) 2008-09-10 2009-09-09 Processes for the preparation of aminosulfone compounds

Publications (1)

Publication Number Publication Date
SMT201300045B true SMT201300045B (it) 2013-07-09

Family

ID=41565187

Family Applications (1)

Application Number Title Priority Date Filing Date
SM201300045T SMT201300045B (it) 2008-09-10 2013-04-19 Processi per la preparazione di composti di amminosolfone

Country Status (15)

Country Link
US (1) US8242310B2 (it)
EP (1) EP2334639B1 (it)
JP (1) JP5513508B2 (it)
CN (1) CN102209709B (it)
CA (1) CA2736171A1 (it)
DK (1) DK2334639T3 (it)
ES (1) ES2404336T3 (it)
HR (1) HRP20130356T1 (it)
MX (1) MX2011002589A (it)
MY (1) MY155424A (it)
PL (1) PL2334639T3 (it)
PT (1) PT2334639E (it)
SI (1) SI2334639T1 (it)
SM (1) SMT201300045B (it)
WO (1) WO2010030345A2 (it)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7893101B2 (en) 2002-03-20 2011-02-22 Celgene Corporation Solid forms comprising (+)-2-[1-(3-ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoisoindoline-1,3-dione, compositions thereof, and uses thereof
US9532977B2 (en) 2010-12-16 2017-01-03 Celgene Corporation Controlled release oral dosage forms of poorly soluble drugs and uses thereof
JP6143675B2 (ja) 2010-12-16 2017-06-07 セルジーン コーポレイション 難溶性薬物の制御放出経口剤形及びその使用
WO2012097116A2 (en) 2011-01-14 2012-07-19 Celgene Corporation Isotopologues of isoindole derivatives
AU2012249536B2 (en) 2011-04-28 2016-09-22 Amgen (Europe) GmbH Methods and compositions using PDE4 inhibitors for the treatment and management of autoimmune and inflammatory diseases
KR20140063808A (ko) 2011-09-14 2014-05-27 셀진 코포레이션 시클로프로판카르복실 산｛２-[(１s)-１-(３-에톡시-４-메톡시-페닐)-２-메탄술포닐-에틸]-３-옥소-２,３-디하이드로-１h-이소인돌-４-일｝-아마이드의 제제
US9126906B2 (en) 2012-02-21 2015-09-08 Celgene Corporation Asymmetric synthetic processes for the preparation of aminosulfone compounds
AR090100A1 (es) 2012-02-21 2014-10-22 Celgene Corp Procesos para la preparacion de la (s)-1-(3-etoxi-4-metoxifenil)-2-metanosulfoniletilamina
EP2764866A1 (en) 2013-02-07 2014-08-13 IP Gesellschaft für Management mbH Inhibitors of nedd8-activating enzyme
AU2014235273A1 (en) 2013-03-14 2015-07-09 Celgene Corporation Treatment of psoriatic arthritis using apremilast
EP3010490A1 (en) 2013-06-17 2016-04-27 Celgene Corporation Tablet formulations of (+)-2-[1 -(3-ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoisoindoline-1,3-dione
US9480676B2 (en) 2014-05-15 2016-11-01 Celgene Corporation Use of PDE4 inhibitors and combinations thereof for the treatment of cystic fibrosis
US20170087129A1 (en) 2014-05-16 2017-03-30 Celgene Corporation Compositions and methods for the treatment of atherosclerotic cardiovascular diseases with pde4 modulators
EP2949645A1 (en) 2014-05-28 2015-12-02 LEK Pharmaceuticals d.d. Processes for the preparation of ß-aminosulfone compounds
EP3157520B1 (en) 2014-06-23 2019-09-04 Celgene Corporation Apremilast for the treatment of a liver disease or a liver function abnormality
WO2016025686A1 (en) 2014-08-15 2016-02-18 Celgene Corporation Dosage titration of apremilast for the treatment of diseases ameliorated by pde4 inhibition
JP2018516912A (ja) * 2015-05-26 2018-06-28 ルピン・リミテッド アプレミラストおよびその新規な多形の改善された製造方法
WO2016199031A1 (en) * 2015-06-09 2016-12-15 Dr. Reddy’S Laboratories Limited Process for preparation of apremilast and its intermediates
EP3106457A1 (en) 2015-06-15 2016-12-21 LEK Pharmaceuticals d.d. A novel synthetic pathway towards apremilast
EP3144393A1 (en) 2015-09-18 2017-03-22 LEK Pharmaceuticals d.d. A synthetic pathway towards apremilast
WO2017059040A1 (en) 2015-09-29 2017-04-06 Pliva Hrvatska D.O.O. Processes for the preparation of apremilast and intermediates thereof
US10682336B2 (en) 2015-10-21 2020-06-16 Amgen Inc. PDE4 modulators for treating and preventing immune reconstitution inflammatory syndrome (IRIS)
EP3373916A1 (en) 2015-11-11 2018-09-19 Celgene Corporation Controlled release oral dosage forms of poorly soluble drugs and uses thereof
US10774041B2 (en) 2016-04-15 2020-09-15 Davuluri Ramamohan Rao Process for the preparation of apremilast
CN106543050B (zh) * 2016-09-28 2018-04-10 中南大学湘雅医院 一种阿普斯特中间体的合成工艺
HRP20210438T1 (hr) 2017-04-04 2021-04-30 Quimica Sintetica, S.A. Racemični beta-aminosulfonski spojevi
SI3606908T1 (sl) 2017-04-04 2020-10-30 Quimica Sintetica, S.A. Delitev racemičnih beta-aminosulfonskih spojin
CN107011209A (zh) * 2017-05-11 2017-08-04 蚌埠中实化学技术有限公司 一种3‑甲氧基‑4‑乙氧基苯腈的合成新工艺
CN115572248B (zh) * 2022-11-08 2024-04-26 中山大学 一种制备β-氨基砜类化合物的方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8501192D0 (en) * 1985-01-17 1985-02-20 Boots Co Plc Therapeutic agents
JPH02289584A (ja) * 1989-02-17 1990-11-29 Takeda Chem Ind Ltd セファロスポリンγ―ラクトン化合物
EP0731086B1 (de) * 1995-03-09 1999-04-28 Ciba SC Holding AG Verfahren zur Herstellung aromatischer Nitrile
JPH1087547A (ja) * 1996-09-13 1998-04-07 Nippon Soda Co Ltd 光学活性合成中間体の製造法
GB9711650D0 (en) * 1997-06-05 1997-07-30 Pfizer Ltd Compounds useful in therapy
US6020358A (en) * 1998-10-30 2000-02-01 Celgene Corporation Substituted phenethylsulfones and method of reducing TNFα levels
DE60330187D1 (de) * 2002-12-30 2009-12-31 Celgene Corp Fluoralkoxy-substituierte 1, 3-dihydro-isoindolyl-verbindungen und ihre pharmazeutischen verwendungen

Also Published As

Publication number Publication date
HRP20130356T1 (en) 2013-05-31
HK1159064A1 (en) 2012-07-27
MY155424A (en) 2015-10-15
MX2011002589A (es) 2011-04-07
CA2736171A1 (en) 2010-03-18
CN102209709A (zh) 2011-10-05
DK2334639T3 (da) 2013-05-06
CN102209709B (zh) 2014-08-13
US8242310B2 (en) 2012-08-14
SI2334639T1 (sl) 2013-06-28
WO2010030345A3 (en) 2010-05-06
PT2334639E (pt) 2013-04-26
EP2334639A2 (en) 2011-06-22
JP2012502097A (ja) 2012-01-26
EP2334639B1 (en) 2013-01-23
PL2334639T3 (pl) 2013-08-30
US20100168475A1 (en) 2010-07-01
WO2010030345A2 (en) 2010-03-18
JP5513508B2 (ja) 2014-06-04
ES2404336T3 (es) 2013-05-27

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