SK9498A3 - Use of calendula glycosides for the treatment of psoriasis - Google Patents
Use of calendula glycosides for the treatment of psoriasis Download PDFInfo
- Publication number
- SK9498A3 SK9498A3 SK94-98A SK9498A SK9498A3 SK 9498 A3 SK9498 A3 SK 9498A3 SK 9498 A SK9498 A SK 9498A SK 9498 A3 SK9498 A3 SK 9498A3
- Authority
- SK
- Slovakia
- Prior art keywords
- compound
- formula
- van
- calendula
- chloroform
- Prior art date
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- SASYSVUEVMOWPL-NXVVXOECSA-N decyl oleate Chemical compound CCCCCCCCCCOC(=O)CCCCCCC\C=C/CCCCCCCC SASYSVUEVMOWPL-NXVVXOECSA-N 0.000 description 1
- 230000002939 deleterious effect Effects 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- IJKVHSBPTUYDLN-UHFFFAOYSA-N dihydroxy(oxo)silane Chemical compound O[Si](O)=O IJKVHSBPTUYDLN-UHFFFAOYSA-N 0.000 description 1
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- 239000002552 dosage form Substances 0.000 description 1
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- YQEMORVAKMFKLG-UHFFFAOYSA-N glycerine monostearate Natural products CCCCCCCCCCCCCCCCCC(=O)OC(CO)CO YQEMORVAKMFKLG-UHFFFAOYSA-N 0.000 description 1
- SVUQHVRAGMNPLW-UHFFFAOYSA-N glycerol monostearate Natural products CCCCCCCCCCCCCCCCC(=O)OCC(O)CO SVUQHVRAGMNPLW-UHFFFAOYSA-N 0.000 description 1
- 230000035876 healing Effects 0.000 description 1
- UBHWBODXJBSFLH-UHFFFAOYSA-N hexadecan-1-ol;octadecan-1-ol Chemical compound CCCCCCCCCCCCCCCCO.CCCCCCCCCCCCCCCCCCO UBHWBODXJBSFLH-UHFFFAOYSA-N 0.000 description 1
- IPCSVZSSVZVIGE-UHFFFAOYSA-M hexadecanoate Chemical compound CCCCCCCCCCCCCCCC([O-])=O IPCSVZSSVZVIGE-UHFFFAOYSA-M 0.000 description 1
- 125000006038 hexenyl group Chemical class 0.000 description 1
- 230000007062 hydrolysis Effects 0.000 description 1
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- 239000008309 hydrophilic cream Substances 0.000 description 1
- 230000002209 hydrophobic effect Effects 0.000 description 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 description 1
- BYSSHGLMQCSIQS-UHFFFAOYSA-N hydroxy(octadecyl)silane Chemical compound CCCCCCCCCCCCCCCCCC[SiH2]O BYSSHGLMQCSIQS-UHFFFAOYSA-N 0.000 description 1
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- 229940078545 isocetyl stearate Drugs 0.000 description 1
- XUGNVMKQXJXZCD-UHFFFAOYSA-N isopropyl palmitate Chemical compound CCCCCCCCCCCCCCCC(=O)OC(C)C XUGNVMKQXJXZCD-UHFFFAOYSA-N 0.000 description 1
- 230000000670 limiting effect Effects 0.000 description 1
- 150000002632 lipids Chemical class 0.000 description 1
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- 239000007937 lozenge Substances 0.000 description 1
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- 235000010355 mannitol Nutrition 0.000 description 1
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- XELZGAJCZANUQH-UHFFFAOYSA-N methyl 1-acetylthieno[3,2-c]pyrazole-5-carboxylate Chemical compound CC(=O)N1N=CC2=C1C=C(C(=O)OC)S2 XELZGAJCZANUQH-UHFFFAOYSA-N 0.000 description 1
- WBYWAXJHAXSJNI-UHFFFAOYSA-N methyl p-hydroxycinnamate Natural products OC(=O)C=CC1=CC=CC=C1 WBYWAXJHAXSJNI-UHFFFAOYSA-N 0.000 description 1
- 235000021243 milk fat Nutrition 0.000 description 1
- 239000002480 mineral oil Substances 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 239000007932 molded tablet Substances 0.000 description 1
- 238000000465 moulding Methods 0.000 description 1
- 239000002324 mouth wash Substances 0.000 description 1
- 229940043348 myristyl alcohol Drugs 0.000 description 1
- 229930014626 natural product Natural products 0.000 description 1
- 238000000655 nuclear magnetic resonance spectrum Methods 0.000 description 1
- 235000014593 oils and fats Nutrition 0.000 description 1
- 239000010502 orange oil Substances 0.000 description 1
- 239000012188 paraffin wax Substances 0.000 description 1
- 235000010603 pastilles Nutrition 0.000 description 1
- 229940049954 penicillin Drugs 0.000 description 1
- 125000002255 pentenyl group Chemical class C(=CCCC)* 0.000 description 1
- 239000008251 pharmaceutical emulsion Substances 0.000 description 1
- 239000003375 plant hormone Substances 0.000 description 1
- 229920001223 polyethylene glycol Polymers 0.000 description 1
- 229920000036 polyvinylpyrrolidone Polymers 0.000 description 1
- 235000013855 polyvinylpyrrolidone Nutrition 0.000 description 1
- 229940069328 povidone Drugs 0.000 description 1
- 230000002335 preservative effect Effects 0.000 description 1
- 238000002203 pretreatment Methods 0.000 description 1
- 125000001436 propyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
- 235000013772 propylene glycol Nutrition 0.000 description 1
- 125000006239 protecting group Chemical group 0.000 description 1
- 239000012673 purified plant extract Substances 0.000 description 1
- 239000012521 purified sample Substances 0.000 description 1
- UMJSCPRVCHMLSP-UHFFFAOYSA-N pyridine Natural products COC1=CC=CN=C1 UMJSCPRVCHMLSP-UHFFFAOYSA-N 0.000 description 1
- 230000000979 retarding effect Effects 0.000 description 1
- 230000006965 reversible inhibition Effects 0.000 description 1
- 239000004576 sand Substances 0.000 description 1
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- 238000000926 separation method Methods 0.000 description 1
- 238000007493 shaping process Methods 0.000 description 1
- 238000010898 silica gel chromatography Methods 0.000 description 1
- 235000012239 silicon dioxide Nutrition 0.000 description 1
- 239000002002 slurry Substances 0.000 description 1
- 229910000029 sodium carbonate Inorganic materials 0.000 description 1
- 229940023144 sodium glycolate Drugs 0.000 description 1
- 235000019333 sodium laurylsulphate Nutrition 0.000 description 1
- 239000008137 solubility enhancer Substances 0.000 description 1
- 238000001179 sorption measurement Methods 0.000 description 1
- 238000004611 spectroscopical analysis Methods 0.000 description 1
- 238000010186 staining Methods 0.000 description 1
- 238000010561 standard procedure Methods 0.000 description 1
- 239000007858 starting material Substances 0.000 description 1
- 239000011550 stock solution Substances 0.000 description 1
- 210000002784 stomach Anatomy 0.000 description 1
- 239000000725 suspension Substances 0.000 description 1
- 238000003786 synthesis reaction Methods 0.000 description 1
- 150000003505 terpenes Chemical class 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- OULAJFUGPPVRBK-UHFFFAOYSA-N tetratriacontyl alcohol Natural products CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCO OULAJFUGPPVRBK-UHFFFAOYSA-N 0.000 description 1
- 239000002562 thickening agent Substances 0.000 description 1
- 229940104230 thymidine Drugs 0.000 description 1
- UAXOELSVPTZZQG-UHFFFAOYSA-N tiglic acid Natural products CC(C)=C(C)C(O)=O UAXOELSVPTZZQG-UHFFFAOYSA-N 0.000 description 1
- 230000036962 time dependent Effects 0.000 description 1
- 230000000699 topical effect Effects 0.000 description 1
- 239000012049 topical pharmaceutical composition Substances 0.000 description 1
- 239000000196 tragacanth Substances 0.000 description 1
- 235000010487 tragacanth Nutrition 0.000 description 1
- 229940116362 tragacanth Drugs 0.000 description 1
- JEJAMASKDTUEBZ-UHFFFAOYSA-N tris(1,1,3-tribromo-2,2-dimethylpropyl) phosphate Chemical compound BrCC(C)(C)C(Br)(Br)OP(=O)(OC(Br)(Br)C(C)(C)CBr)OC(Br)(Br)C(C)(C)CBr JEJAMASKDTUEBZ-UHFFFAOYSA-N 0.000 description 1
- 239000012588 trypsin Substances 0.000 description 1
- 231100000397 ulcer Toxicity 0.000 description 1
- 238000005292 vacuum distillation Methods 0.000 description 1
- 239000001993 wax Substances 0.000 description 1
- OENHQHLEOONYIE-JLTXGRSLSA-N β-Carotene Chemical compound CC=1CCCC(C)(C)C=1\C=C\C(\C)=C\C=C\C(\C)=C\C=C\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C OENHQHLEOONYIE-JLTXGRSLSA-N 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
- A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
- A61K31/704—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Molecular Biology (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Dermatology (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Plant Substances (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Fats And Perfumes (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
- Fertilizers (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9515214.6A GB9515214D0 (en) | 1995-07-25 | 1995-07-25 | Plant extracts |
| PCT/GB1996/001792 WO1997004788A2 (fr) | 1995-07-25 | 1996-07-24 | Utilisation de glycosides de calendula dans le traitement du psoriasis |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SK9498A3 true SK9498A3 (en) | 1998-09-09 |
Family
ID=10778203
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SK94-98A SK9498A3 (en) | 1995-07-25 | 1996-07-24 | Use of calendula glycosides for the treatment of psoriasis |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US6225342B1 (fr) |
| EP (1) | EP0848612B1 (fr) |
| JP (1) | JP4384261B2 (fr) |
| KR (1) | KR19990035847A (fr) |
| CN (1) | CN1191488A (fr) |
| AT (1) | ATE236643T1 (fr) |
| AU (1) | AU6621096A (fr) |
| BG (1) | BG102250A (fr) |
| BR (1) | BR9609910A (fr) |
| CA (1) | CA2227751A1 (fr) |
| CZ (1) | CZ19498A3 (fr) |
| DE (1) | DE69627354T2 (fr) |
| EE (1) | EE9800032A (fr) |
| ES (1) | ES2197242T3 (fr) |
| GB (1) | GB9515214D0 (fr) |
| HU (1) | HUP9802861A3 (fr) |
| IS (1) | IS4651A (fr) |
| NO (1) | NO980317L (fr) |
| PL (1) | PL324655A1 (fr) |
| SK (1) | SK9498A3 (fr) |
| WO (1) | WO1997004788A2 (fr) |
| ZA (1) | ZA966298B (fr) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6753006B1 (en) | 1993-02-22 | 2004-06-22 | American Bioscience, Inc. | Paclitaxel-containing formulations |
| GB9701415D0 (en) * | 1997-01-24 | 1997-03-12 | Univ Strathclyde | Stereoisomers |
| GB9809889D0 (en) | 1998-05-11 | 1998-07-08 | Univ Strathclyde | Prevention of restenosis |
| JP2003504340A (ja) * | 1999-07-09 | 2003-02-04 | ベーエスペー ファルマ アクティーゼルスカブ | ブチロスペルマムパルキイの抽出物を含有する組成物および薬剤または栄養補助食品としての使用 |
| US6440465B1 (en) * | 2000-05-01 | 2002-08-27 | Bioderm, Inc. | Topical composition for the treatment of psoriasis and related skin disorders |
| US20050003023A1 (en) * | 2002-06-28 | 2005-01-06 | Meisner Lorraine Faxon | Topical composition for the treatment of psoriasis and related skin disorders |
| US20030054042A1 (en) * | 2001-09-14 | 2003-03-20 | Elaine Liversidge | Stabilization of chemical compounds using nanoparticulate formulations |
| US7887860B2 (en) * | 2001-12-28 | 2011-02-15 | Inter American University Of Puerto Rico | Anti-bacterial plant compositions |
| CA2479665C (fr) * | 2002-03-20 | 2011-08-30 | Elan Pharma International Ltd. | Compositions nanoparticulaires d'inhibiteurs d'angiogenese |
| US20080220075A1 (en) * | 2002-03-20 | 2008-09-11 | Elan Pharma International Ltd. | Nanoparticulate compositions of angiogenesis inhibitors |
| US20050152996A1 (en) * | 2003-12-01 | 2005-07-14 | BUTLER Donald | Extracts of Mimulus aurantiacus for treating psoriasis and repelling insects |
| BG65694B1 (bg) * | 2003-12-31 | 2009-07-31 | НАЙДЕНОВ Владимир | Средство за лечение на дерматози |
| US20060076536A1 (en) * | 2004-09-29 | 2006-04-13 | Barshied Scott R | Oxygen scavenging pharmaceutical package and methods for making same |
| PL409156A1 (pl) | 2014-08-11 | 2016-02-15 | Matonis Grzegorz | Kompozycja kosmetyczna i/lub farmaceutyczna łagodząca objawy łuszczycy |
| US20200030226A1 (en) | 2018-07-27 | 2020-01-30 | Johnson & Johnson Consumer Inc. | Botanical and bacterial extracts displaying retinol-like activity |
| US11197841B2 (en) | 2019-07-23 | 2021-12-14 | Johnson & Johnson Surgical Vision, Inc. | Compositions and methods for treating the eye |
| JP7374986B2 (ja) | 2018-07-27 | 2023-11-07 | ジョンソン・アンド・ジョンソン・サージカル・ビジョン・インコーポレイテッド | 眼を治療するための組成物及び方法 |
| US10966948B2 (en) | 2019-07-23 | 2021-04-06 | Johnson & Johnson Surgical Vision, Inc. | Compositions and methods for treating the eye |
| CN109516983A (zh) * | 2018-11-20 | 2019-03-26 | 广东药科大学 | 一种中药草本祛痘化合物及其组合物 |
| US11969454B2 (en) | 2019-11-19 | 2024-04-30 | Johnson & Johnson Surgical Vision, Inc. | Compositions and methods for treating the eye |
| CN114159453A (zh) | 2021-12-24 | 2022-03-11 | 广西馨海药业科技有限公司 | 白头翁皂苷b4在制备治疗或预防银屑病的药物的用途 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5165932A (en) | 1987-12-23 | 1992-11-24 | Unipharma Co., Ltd. | Therapeutical compositions against psoriasis |
| DE3836519C2 (de) | 1988-10-26 | 1994-03-10 | Cutan Kosmetik Vertriebs Gmbh | Verwendung einer pharmazeutischen Zubereitung auf der Basis von Calendula officinalis zur Behandlung von Psoriasis |
| HU203668B (en) | 1990-04-03 | 1991-09-30 | Tamas Angeli | Cosmetic containing medicinal plants and process for producing composition against psoriasis |
-
1995
- 1995-07-25 GB GBGB9515214.6A patent/GB9515214D0/en active Pending
-
1996
- 1996-07-24 WO PCT/GB1996/001792 patent/WO1997004788A2/fr not_active Ceased
- 1996-07-24 EE EE9800032A patent/EE9800032A/xx unknown
- 1996-07-24 ZA ZA9606298A patent/ZA966298B/xx unknown
- 1996-07-24 SK SK94-98A patent/SK9498A3/sk unknown
- 1996-07-24 CA CA002227751A patent/CA2227751A1/fr not_active Abandoned
- 1996-07-24 CN CN96195818A patent/CN1191488A/zh active Pending
- 1996-07-24 PL PL96324655A patent/PL324655A1/xx unknown
- 1996-07-24 JP JP50733497A patent/JP4384261B2/ja not_active Expired - Fee Related
- 1996-07-24 AT AT96925837T patent/ATE236643T1/de not_active IP Right Cessation
- 1996-07-24 ES ES96925837T patent/ES2197242T3/es not_active Expired - Lifetime
- 1996-07-24 CZ CZ98194A patent/CZ19498A3/cs unknown
- 1996-07-24 AU AU66210/96A patent/AU6621096A/en not_active Abandoned
- 1996-07-24 HU HU9802861A patent/HUP9802861A3/hu unknown
- 1996-07-24 EP EP96925837A patent/EP0848612B1/fr not_active Expired - Lifetime
- 1996-07-24 BR BR9609910A patent/BR9609910A/pt not_active Application Discontinuation
- 1996-07-24 DE DE69627354T patent/DE69627354T2/de not_active Expired - Fee Related
- 1996-07-24 US US09/000,265 patent/US6225342B1/en not_active Expired - Lifetime
- 1996-07-24 KR KR1019980700507A patent/KR19990035847A/ko not_active Withdrawn
-
1998
- 1998-01-16 IS IS4651A patent/IS4651A/is unknown
- 1998-01-23 NO NO980317A patent/NO980317L/no unknown
- 1998-02-13 BG BG102250A patent/BG102250A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ZA966298B (en) | 1997-02-11 |
| WO1997004788A3 (fr) | 1997-03-27 |
| CZ19498A3 (cs) | 1998-09-16 |
| JP4384261B2 (ja) | 2009-12-16 |
| EP0848612A2 (fr) | 1998-06-24 |
| HUP9802861A2 (hu) | 1999-04-28 |
| ATE236643T1 (de) | 2003-04-15 |
| CA2227751A1 (fr) | 1997-02-13 |
| BG102250A (en) | 1999-02-26 |
| MX9800697A (es) | 1998-09-30 |
| IS4651A (is) | 1998-01-16 |
| BR9609910A (pt) | 1999-06-15 |
| HUP9802861A3 (en) | 1999-08-30 |
| US6225342B1 (en) | 2001-05-01 |
| CN1191488A (zh) | 1998-08-26 |
| NO980317D0 (no) | 1998-01-23 |
| ES2197242T3 (es) | 2004-01-01 |
| KR19990035847A (ko) | 1999-05-25 |
| DE69627354T2 (de) | 2004-03-04 |
| GB9515214D0 (en) | 1995-09-20 |
| JPH11510153A (ja) | 1999-09-07 |
| DE69627354D1 (de) | 2003-05-15 |
| EE9800032A (et) | 1998-08-17 |
| WO1997004788A2 (fr) | 1997-02-13 |
| NO980317L (no) | 1998-03-24 |
| AU6621096A (en) | 1997-02-26 |
| EP0848612B1 (fr) | 2003-04-09 |
| PL324655A1 (en) | 1998-06-08 |
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