SK16082000A3 - Ľudský bmp-7 promótor a spôsob výskumu substancií ovplyvňujúcich kosť pri použití tohto promótora - Google Patents

Ľudský bmp-7 promótor a spôsob výskumu substancií ovplyvňujúcich kosť pri použití tohto promótora Download PDF

Info

Publication number: SK16082000A3
Authority: SK; Slovakia
Prior art keywords: bone; vector; dna; human; human bmp
Prior art date: 1998-04-30

Application number

SK1608-2000A

Other languages

English (en)

Slovak (sk)

Inventor

Shinji Kawai

Takeyuki Sugiura

Original Assignee

Hoechst Marion Roussel

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-04-30

Filing date

1999-04-22

Publication date

2001-05-10

1999-04-22 Application filed by Hoechst Marion Roussel filed Critical Hoechst Marion Roussel

2001-05-10 Publication of SK16082000A3 publication Critical patent/SK16082000A3/sk

Links

238000000034 method Methods 0.000 title claims abstract description 19
239000000126 substance Substances 0.000 title claims description 31
210000000988 bone and bone Anatomy 0.000 title abstract description 17
101100165560 Mus musculus Bmp7 gene Proteins 0.000 title 1
101000899361 Homo sapiens Bone morphogenetic protein 7 Proteins 0.000 claims abstract description 27
239000013598 vector Substances 0.000 claims abstract description 21
230000000694 effects Effects 0.000 claims abstract description 16
108700008625 Reporter Genes Proteins 0.000 claims abstract description 15
208000017169 kidney disease Diseases 0.000 claims abstract description 6
230000002401 inhibitory effect Effects 0.000 claims abstract description 5
239000013604 expression vector Substances 0.000 claims description 21
238000003259 recombinant expression Methods 0.000 claims description 21
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238000002955 isolation Methods 0.000 claims description 3
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239000002773 nucleotide Substances 0.000 claims description 2
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108090000654 Bone morphogenetic protein 1 Proteins 0.000 description 1
102100028728 Bone morphogenetic protein 1 Human genes 0.000 description 1
102100022544 Bone morphogenetic protein 7 Human genes 0.000 description 1
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206010009269 Cleft palate Diseases 0.000 description 1
108091026890 Coding region Proteins 0.000 description 1
206010010356 Congenital anomaly Diseases 0.000 description 1
108090000331 Firefly luciferases Proteins 0.000 description 1
206010017076 Fracture Diseases 0.000 description 1
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241001465754 Metazoa Species 0.000 description 1
101000762365 Mus musculus Bone morphogenetic protein 2 Proteins 0.000 description 1
206010028980 Neoplasm Diseases 0.000 description 1
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108091023040 Transcription factor Proteins 0.000 description 1
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230000034127 bone morphogenesis Effects 0.000 description 1
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238000002224 dissection Methods 0.000 description 1
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239000001963 growth medium Substances 0.000 description 1
238000013537 high throughput screening Methods 0.000 description 1
238000000338 in vitro Methods 0.000 description 1
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208000014674 injury Diseases 0.000 description 1
238000003780 insertion Methods 0.000 description 1
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238000011835 investigation Methods 0.000 description 1
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238000003670 luciferase enzyme activity assay Methods 0.000 description 1
239000000463 material Substances 0.000 description 1
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239000005445 natural material Substances 0.000 description 1
108020004707 nucleic acids Proteins 0.000 description 1
102000039446 nucleic acids Human genes 0.000 description 1
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201000008968 osteosarcoma Diseases 0.000 description 1
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Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/51—Bone morphogenetic factor; Osteogenins; Osteogenic factor; Bone-inducing factor
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
Genetics & Genomics (AREA)
General Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Medicinal Chemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Zoology (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
Animal Behavior & Ethology (AREA)
Molecular Biology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Biophysics (AREA)
Biochemistry (AREA)
Toxicology (AREA)
Biomedical Technology (AREA)
Gastroenterology & Hepatology (AREA)
Wood Science & Technology (AREA)
General Engineering & Computer Science (AREA)
Biotechnology (AREA)
Orthopedic Medicine & Surgery (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Endocrinology (AREA)
Physics & Mathematics (AREA)
Reproductive Health (AREA)
Physical Education & Sports Medicine (AREA)
Plant Pathology (AREA)
Microbiology (AREA)
Urology & Nephrology (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

SK1608-2000A 1998-04-30 1999-04-22 Ľudský bmp-7 promótor a spôsob výskumu substancií ovplyvňujúcich kosť pri použití tohto promótora SK16082000A3 (sk)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
JP10120174A JPH11313675A (ja)	1998-04-30	1998-04-30	ヒトｂｍｐ−７プロモーターおよびこれを用いた骨関連物質の探索法
PCT/IB1999/000733 WO1999057293A1 (en)	1998-04-30	1999-04-22	Human bmp-7 promoter and method for exploring bone-related substance by using the same

Publications (1)

Publication Number	Publication Date
SK16082000A3 true SK16082000A3 (sk)	2001-05-10

Family

ID=14779761

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
SK1608-2000A SK16082000A3 (sk)	1998-04-30	1999-04-22	Ľudský bmp-7 promótor a spôsob výskumu substancií ovplyvňujúcich kosť pri použití tohto promótora

Country Status (26)

Country	Link
US (2)	US6534268B1 (xx)
EP (1)	EP1076713A1 (xx)
JP (1)	JPH11313675A (xx)
KR (1)	KR20010071193A (xx)
CN (1)	CN1170941C (xx)
AP (1)	AP1329A (xx)
AU (1)	AU769124B2 (xx)
BG (1)	BG64780B1 (xx)
BR (1)	BR9910585A (xx)
CA (1)	CA2326957A1 (xx)
EA (1)	EA004509B1 (xx)
EE (1)	EE200000627A (xx)
GE (1)	GEP20033056B (xx)
HR (1)	HRP20000736A2 (xx)
HU (1)	HUP0102329A3 (xx)
ID (1)	ID26704A (xx)
IL (1)	IL139100A0 (xx)
NO (1)	NO20005433D0 (xx)
NZ (1)	NZ507625A (xx)
PL (1)	PL343817A1 (xx)
SK (1)	SK16082000A3 (xx)
TR (1)	TR200003182T2 (xx)
UA (1)	UA72212C2 (xx)
WO (1)	WO1999057293A1 (xx)
YU (1)	YU64900A (xx)
ZA (1)	ZA200006080B (xx)

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* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JP2006516548A (ja)	2002-12-30	2006-07-06	アンジオテックインターナショナルアクツィエンゲゼルシャフト	迅速ゲル化ポリマー組成物からの薬物送達法
US20070015701A1 (en) *	2005-06-01	2007-01-18	Samuel Zalipsky	Macromolecular conjugates of bone morphogenetic protein-7
DK2078073T3 (da) *	2006-10-12	2013-10-28	Ethicon Inc	Nyreafledte celler og fremgangsmåder til anvendelse deraf til vævsreparation og -regenerering
CA2681317C (en) *	2008-05-16	2013-04-02	Industry Foundation Of Chonnam National University	A synthetic peptide containing bone forming peptide 1(bfp 1) for stimulating osteoblast differentiation, and pharmaceutical composition comprising the synthetic peptide
CA2799641C (en)	2010-06-09	2016-08-30	Semprus Biosciences Corp.	Articles having non-fouling surfaces and processes for preparing the same including applying a primer coat
CA2799786A1 (en)	2010-06-09	2011-12-15	Semprus Biosciences Corp.	Non-fouling, anti-microbial, anti-thrombogenic graft compositions
KR20130110143A (ko)	2010-06-09	2013-10-08	셈프러스 바이오사이언시스 코퍼레이션	방오성, 항균성, 항혈전성 그라프트-프롬 조성물
WO2012024489A2 (en)	2010-08-18	2012-02-23	Emory University	Compounds and compositions for ossification and methods related thereto
WO2012116137A2 (en)	2011-02-24	2012-08-30	Emory University	Jab1 blocking compositions for ossification and methods related thereto
EP2678050B1 (en)	2011-02-24	2020-10-14	Emory University	Noggin blocking compositions for ossification and methods related thereto
JP2015507761A (ja)	2011-12-14	2015-03-12	センプラス・バイオサイエンシーズ・コーポレイションＳｅｍｐｒｕｓＢｉｏｓｃｉｅｎｃｅｓＣｏｒｐ．	コンタクトレンズ改質のためのレドックス法
EP2791211A4 (en)	2011-12-14	2015-08-05	Semprus Biosciences Corp	MULTI-STAGE UV PROCESS FOR CREATING CONTACT LENSES WITH MODIFIED SURFACE
US9006359B2 (en)	2011-12-14	2015-04-14	Semprus Biosciences Corporation	Imbibing process for contact lens surface modification
MX2014007211A (es)	2011-12-14	2015-04-14	Semprus Biosciences Corp	Lente de contacto de hidrogel de silicona modificada usando oxidantes de lantanido o de metal de transicion.
MX2014007202A (es)	2011-12-14	2015-03-09	Semprus Biosciences Corp	Lentes de contacto modificadas en la superficie.
WO2019005563A1 (en) *	2017-06-27	2019-01-03	St. Jude Children's Research Hospital	METHODS ASSOCIATED WITH THE ACTIVATION OF THE SIGNALING PATHWAY OF BONE MORPHOGENETIC PROTEINS

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5266683A (en) *	1988-04-08	1993-11-30	Stryker Corporation	Osteogenic proteins
DE69031939T2 (de)	1989-03-28	1998-09-10	Genetics Institute, Inc., Cambridge, Mass.	Osteoinduktive zusammensetzungen
US5650276A (en) *	1991-03-11	1997-07-22	Creative Biomolecules, Inc.	Morphogenic protein screening method
WO1993003382A2 (en) *	1991-08-01	1993-02-18	Pharmaceutical Discovery Corporation	Characterization of specific drug receptors with fluorescent ligands
CA2191583C (en) *	1994-06-07	2007-03-27	Engin Ozkaynak	Methods and compositions for modulating morphogenic protein expression
US6083690A (en) *	1995-06-02	2000-07-04	Osteoscreen, Inc.	Methods and compositions for identifying osteogenic agents
EP0937145A1 (en) *	1996-11-22	1999-08-25	Akzo Nobel N.V.	Bmp-4 promoter and use thereof in screening of therapeutic agents for the prevention and/or treatment of osteoporosis
US5863790A (en)	1997-05-14	1999-01-26	Minnesota Mining And Manfacturing Company	Biological sterility indicator
US6828095B1 (en) *	1997-05-29	2004-12-07	Curis, Inc.	Modulators of morphogen expression and methods of identifying the same

1998
- 1998-04-30 JP JP10120174A patent/JPH11313675A/ja active Pending
1999
- 1999-04-22 YU YU64900A patent/YU64900A/sh unknown
- 1999-04-22 KR KR1020007012054A patent/KR20010071193A/ko not_active Ceased
- 1999-04-22 EE EEP200000627A patent/EE200000627A/xx unknown
- 1999-04-22 AP APAP/P/2000/001982A patent/AP1329A/en active
- 1999-04-22 SK SK1608-2000A patent/SK16082000A3/sk unknown
- 1999-04-22 AU AU31634/99A patent/AU769124B2/en not_active Ceased
- 1999-04-22 PL PL99343817A patent/PL343817A1/xx not_active Application Discontinuation
- 1999-04-22 NZ NZ507625A patent/NZ507625A/en unknown
- 1999-04-22 TR TR2000/03182T patent/TR200003182T2/xx unknown
- 1999-04-22 UA UA2000116830A patent/UA72212C2/uk unknown
- 1999-04-22 IL IL13910099A patent/IL139100A0/xx unknown
- 1999-04-22 CA CA002326957A patent/CA2326957A1/en not_active Abandoned
- 1999-04-22 EA EA200001130A patent/EA004509B1/ru not_active IP Right Cessation
- 1999-04-22 GE GEAP19995635A patent/GEP20033056B/en unknown
- 1999-04-22 WO PCT/IB1999/000733 patent/WO1999057293A1/en not_active Ceased
- 1999-04-22 BR BR9910585-3A patent/BR9910585A/pt not_active IP Right Cessation
- 1999-04-22 CN CNB998079553A patent/CN1170941C/zh not_active Expired - Fee Related
- 1999-04-22 EP EP99913528A patent/EP1076713A1/en not_active Withdrawn
- 1999-04-22 US US09/674,311 patent/US6534268B1/en not_active Expired - Fee Related
- 1999-04-22 HU HU0102329A patent/HUP0102329A3/hu unknown
- 1999-04-22 HR HR20000736A patent/HRP20000736A2/hr not_active Application Discontinuation
- 1999-04-22 ID IDW20002196A patent/ID26704A/id unknown
2000
- 2000-10-24 BG BG104883A patent/BG64780B1/bg unknown
- 2000-10-27 ZA ZA200006080A patent/ZA200006080B/xx unknown
- 2000-10-27 NO NO20005433A patent/NO20005433D0/no not_active Application Discontinuation
2002
- 2002-10-03 US US10/263,788 patent/US20030040007A1/en not_active Abandoned

Also Published As

Publication number	Publication date
AU769124B2 (en)	2004-01-15
CA2326957A1 (en)	1999-11-11
EP1076713A1 (en)	2001-02-21
US20030040007A1 (en)	2003-02-27
NO20005433L (no)	2000-10-27
UA72212C2 (en)	2005-02-15
BR9910585A (pt)	2001-01-09
US6534268B1 (en)	2003-03-18
ZA200006080B (en)	2001-10-29
ID26704A (id)	2001-02-01
KR20010071193A (ko)	2001-07-28
EE200000627A (et)	2002-02-15
EA200001130A1 (ru)	2001-04-23
NZ507625A (en)	2003-12-19
CN1170941C (zh)	2004-10-13
JPH11313675A (ja)	1999-11-16
GEP20033056B (en)	2003-08-25
BG64780B1 (bg)	2006-03-31
HUP0102329A2 (hu)	2001-10-28
CN1307643A (zh)	2001-08-08
WO1999057293A1 (en)	1999-11-11
EA004509B1 (ru)	2004-04-29
IL139100A0 (en)	2001-11-25
YU64900A (sh)	2003-10-31
HUP0102329A3 (en)	2006-03-28
NO20005433D0 (no)	2000-10-27
PL343817A1 (en)	2001-09-10
HRP20000736A2 (en)	2001-10-31
AU3163499A (en)	1999-11-23
AP2000001982A0 (en)	2000-12-31
AP1329A (en)	2004-11-22
TR200003182T2 (tr)	2001-02-21
BG104883A (en)	2001-05-31

Publication	Publication Date	Title
Villarreal et al.	1989	Structure of human osteonectin based upon analysis of cDNA and genomic sequences
US6534268B1 (en)	2003-03-18	Human BMP-7 promoter and method for exploring bone-related substance by using the same
Teufel et al.	2002	Frcp1 and Frcp2, two novel fibronectin type III repeat containing genes
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