SK11362000A3 - Spôsob zlepšenia sexuálnej dysfunkcie žien - Google Patents

Spôsob zlepšenia sexuálnej dysfunkcie žien Download PDF

Info

Publication number: SK11362000A3
Authority: SK; Slovakia
Prior art keywords: apomorphine; women; blood flow; cyclodextrin; administered
Prior art date: 1998-01-30

Application number

SK1136-2000A

Other languages

English (en)

Slovak (sk)

Inventor

Ragab El-Rashidy

Bruce Ronsen

Original Assignee

Pentech Pharmaceuticals, Inc.

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-01-30

Filing date

1999-01-28

Publication date

2001-02-12

1999-01-28 Application filed by Pentech Pharmaceuticals, Inc. filed Critical Pentech Pharmaceuticals, Inc.

2001-02-12 Publication of SK11362000A3 publication Critical patent/SK11362000A3/sk

Links

206010057671 Female sexual dysfunction Diseases 0.000 title claims description 12
229960004046 apomorphine Drugs 0.000 claims abstract description 84
VMWNQDUVQKEIOC-CYBMUJFWSA-N apomorphine Chemical compound C([C@H]1N(C)CC2)C3=CC=C(O)C(O)=C3C3=C1C2=CC=C3 VMWNQDUVQKEIOC-CYBMUJFWSA-N 0.000 claims abstract description 84
230000017531 blood circulation Effects 0.000 claims abstract description 37
230000036470 plasma concentration Effects 0.000 claims abstract description 9
201000001880 Sexual dysfunction Diseases 0.000 claims abstract description 7
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238000000034 method Methods 0.000 claims description 17
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239000000203 mixture Substances 0.000 claims description 14
229920000858 Cyclodextrin Polymers 0.000 claims description 13
238000009472 formulation Methods 0.000 claims description 13
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WHGYBXFWUBPSRW-FOUAGVGXSA-N beta-cyclodextrin Chemical compound OC[C@H]([C@H]([C@@H]([C@H]1O)O)O[C@H]2O[C@@H]([C@@H](O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O3)[C@H](O)[C@H]2O)CO)O[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@@H]3O[C@@H]1CO WHGYBXFWUBPSRW-FOUAGVGXSA-N 0.000 claims description 9
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ODLHGICHYURWBS-LKONHMLTSA-N trappsol cyclo Chemical compound CC(O)COC[C@H]([C@H]([C@@H]([C@H]1O)O)O[C@H]2O[C@@H]([C@@H](O[C@H]3O[C@H](COCC(C)O)[C@H]([C@@H]([C@H]3O)O)O[C@H]3O[C@H](COCC(C)O)[C@H]([C@@H]([C@H]3O)O)O[C@H]3O[C@H](COCC(C)O)[C@H]([C@@H]([C@H]3O)O)O[C@H]3O[C@H](COCC(C)O)[C@H]([C@@H]([C@H]3O)O)O3)[C@H](O)[C@H]2O)COCC(O)C)O[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@@H]3O[C@@H]1COCC(C)O ODLHGICHYURWBS-LKONHMLTSA-N 0.000 claims description 6
QCQCHGYLTSGIGX-GHXANHINSA-N 4-[[(3ar,5ar,5br,7ar,9s,11ar,11br,13as)-5a,5b,8,8,11a-pentamethyl-3a-[(5-methylpyridine-3-carbonyl)amino]-2-oxo-1-propan-2-yl-4,5,6,7,7a,9,10,11,11b,12,13,13a-dodecahydro-3h-cyclopenta[a]chrysen-9-yl]oxy]-2,2-dimethyl-4-oxobutanoic acid Chemical compound N([C@@]12CC[C@@]3(C)[C@]4(C)CC[C@H]5C(C)(C)[C@@H](OC(=O)CC(C)(C)C(O)=O)CC[C@]5(C)[C@H]4CC[C@@H]3C1=C(C(C2)=O)C(C)C)C(=O)C1=CN=CC(C)=C1 QCQCHGYLTSGIGX-GHXANHINSA-N 0.000 claims description 4
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Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/485—Morphinan derivatives, e.g. morphine, codeine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/02—Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders

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Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
Reproductive Health (AREA)
Endocrinology (AREA)
Bioinformatics & Cheminformatics (AREA)
Emergency Medicine (AREA)
Epidemiology (AREA)
Gynecology & Obstetrics (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicinal Preparation (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Compounds Of Unknown Constitution (AREA)
Medicines Containing Plant Substances (AREA)
Other In-Based Heterocyclic Compounds (AREA)

SK1136-2000A 1998-01-30 1999-01-28 Spôsob zlepšenia sexuálnej dysfunkcie žien SK11362000A3 (sk)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US09/016,252 US5945117A (en)	1998-01-30	1998-01-30	Treatment of female sexual dysfunction
PCT/US1999/001776 WO1999038467A1 (fr)	1998-01-30	1999-01-28	Traitement de la dysfonction sexuelle chez la femme

Publications (1)

Publication Number	Publication Date
SK11362000A3 true SK11362000A3 (sk)	2001-02-12

Family

ID=21776169

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
SK1136-2000A SK11362000A3 (sk)	1998-01-30	1999-01-28	Spôsob zlepšenia sexuálnej dysfunkcie žien

Country Status (34)

Country	Link
US (2)	US5945117A (fr)
EP (1)	EP1056419A4 (fr)
JP (1)	JP2002501875A (fr)
KR (1)	KR20010040477A (fr)
CN (1)	CN1250221C (fr)
AR (1)	AR017976A1 (fr)
AU (1)	AU752928B2 (fr)
BG (1)	BG64667B1 (fr)
BR (1)	BR9908038A (fr)
CA (1)	CA2322289A1 (fr)
CO (1)	CO4970819A1 (fr)
CR (1)	CR5959A (fr)
DZ (1)	DZ2714A1 (fr)
GC (1)	GC0000096A (fr)
GT (1)	GT199900013A (fr)
HK (1)	HK1040901B (fr)
HN (1)	HN1999000015A (fr)
HU (1)	HUP0101268A3 (fr)
IL (2)	IL137569A0 (fr)
JO (1)	JO2085B1 (fr)
MA (1)	MA26600A1 (fr)
MX (1)	MXPA00007447A (fr)
NO (1)	NO319821B1 (fr)
NZ (1)	NZ506597A (fr)
PA (1)	PA8467801A1 (fr)
PE (1)	PE20000240A1 (fr)
PL (1)	PL194350B1 (fr)
SK (1)	SK11362000A3 (fr)
TN (1)	TNSN99008A1 (fr)
TR (1)	TR200002220T2 (fr)
TW (1)	TW550069B (fr)
UY (1)	UY25374A1 (fr)
WO (1)	WO1999038467A1 (fr)
ZA (1)	ZA99686B (fr)

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US20040138291A1 (en) *	2002-10-10	2004-07-15	Adams Michael A.	Treatment of sexual dysfunction
CA2451267A1 (fr) *	2002-12-13	2004-06-13	Warner-Lambert Company Llc	Utilisations pharmaceutiques de ligands alpha2delta
US20040204439A1 (en) *	2003-04-14	2004-10-14	Staniforth John Nicholas	Composition, device, and method for treating sexual dysfunction via inhalation
WO2004089374A1 (fr) *	2003-04-14	2004-10-21	Vectura Ltd	Compositions pharmaceutiques comprenant de l'apomorphine pour l'inhalation pulmonaire
US7276246B2 (en) *	2003-05-09	2007-10-02	Cephalon, Inc.	Dissolvable backing layer for use with a transmucosal delivery device
US7306812B2 (en)	2003-05-09	2007-12-11	Cephalon, Inc.	Dissolvable backing layer for use with a transmucosal delivery device
GB0314054D0 (en) *	2003-06-17	2003-07-23	Pfizer Ltd	Amide derivatives as selective serotonin re-uptake inhibitors
US20050054688A1 (en) *	2003-08-08	2005-03-10	Pfizer Inc	Selective serotonin reuptake inhibitors in the treatment of disease
DE10338174A1 (de) *	2003-08-20	2005-03-24	Lts Lohmann Therapie-Systeme Ag	Transdermale Arzneimittelzubereitungen mit Wirkstoffkombinationen zur Behandlung der Parkinson-Krankheit
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AP2006003771A0 (en) *	2004-04-30	2006-10-31	Warner Lambert Co	Substituted morpholine compounds for the treatmentof central nervous system disorders
JP2008533193A (ja) *	2005-03-21	2008-08-21	ファイザー・リミテッド	オキシトシン拮抗薬としての置換トリアゾール誘導体
ES2313626T3 (es) *	2005-03-21	2009-03-01	Pfizer Limited	Derivados de triazol sustituidos como antagonistas de oxitocina.
WO2006105615A1 (fr) *	2005-04-08	2006-10-12	Ozpharma Pty Ltd	Procede d’administration orale
WO2007017752A1 (fr) *	2005-08-10	2007-02-15	Pfizer Limited	Derives de triazole substitues en tant qu'antagonistes d'oxytocine
US8349850B2 (en) *	2006-03-28	2013-01-08	Atir Holding S.A.	Heterocyclic compounds and uses thereof in the treatment of sexual disorders
US7800094B2 (en) *	2007-06-11	2010-09-21	Macronix International Co., Ltd.	Resistance memory with tungsten compound and manufacturing
CA2765291C (fr) *	2009-06-12	2016-03-08	Adagio Pharmaceuticals Ltd.	Apomorphine sublinguale
WO2011130608A1 (fr) *	2010-04-15	2011-10-20	Life Science Enhancement Corporation	Procédés et compositions pour stimuler l'excitation sexuelle chez la femme et traiter un trouble sexuel chez la femme
KR101890317B1 (ko) *	2010-12-16	2018-08-22	선오비온 파마슈티컬스 인코포레이티드	설하 필름
US9353067B2 (en)	2011-04-10	2016-05-31	Atir Holding S.A.	Heterocyclic compounds and uses thereof in the treatment of sexual disorders
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1998
- 1998-01-30 US US09/016,252 patent/US5945117A/en not_active Expired - Fee Related
1999
- 1999-01-21 TN TNTNSN99008A patent/TNSN99008A1/fr unknown
- 1999-01-28 EP EP99905497A patent/EP1056419A4/fr not_active Withdrawn
- 1999-01-28 IL IL13756999A patent/IL137569A0/xx active IP Right Grant
- 1999-01-28 WO PCT/US1999/001776 patent/WO1999038467A1/fr not_active Ceased
- 1999-01-28 CR CR5959A patent/CR5959A/es not_active Application Discontinuation
- 1999-01-28 MX MXPA00007447A patent/MXPA00007447A/es not_active IP Right Cessation
- 1999-01-28 SK SK1136-2000A patent/SK11362000A3/sk unknown
- 1999-01-28 JO JO19992085A patent/JO2085B1/en active
- 1999-01-28 CA CA002322289A patent/CA2322289A1/fr not_active Abandoned
- 1999-01-28 TR TR2000/02220T patent/TR200002220T2/xx unknown
- 1999-01-28 HK HK02101988.0A patent/HK1040901B/zh not_active IP Right Cessation
- 1999-01-28 AU AU25644/99A patent/AU752928B2/en not_active Ceased
- 1999-01-28 HU HU0101268A patent/HUP0101268A3/hu unknown
- 1999-01-28 CN CNB998044423A patent/CN1250221C/zh not_active Expired - Fee Related
- 1999-01-28 KR KR1020007008333A patent/KR20010040477A/ko not_active Ceased
- 1999-01-28 ZA ZA9900686A patent/ZA99686B/xx unknown
- 1999-01-28 JP JP2000529203A patent/JP2002501875A/ja not_active Withdrawn
- 1999-01-28 BR BR9908038-9A patent/BR9908038A/pt not_active Application Discontinuation
- 1999-01-28 NZ NZ506597A patent/NZ506597A/en unknown
- 1999-01-28 HN HN1999000015A patent/HN1999000015A/es unknown
- 1999-01-28 PL PL99342062A patent/PL194350B1/pl unknown
- 1999-01-29 AR ARP990100389A patent/AR017976A1/es not_active Application Discontinuation
- 1999-01-29 CO CO99005067A patent/CO4970819A1/es unknown
- 1999-01-29 UY UY25374A patent/UY25374A1/es not_active Application Discontinuation
- 1999-01-29 PA PA19998467801A patent/PA8467801A1/es unknown
- 1999-01-29 MA MA25442A patent/MA26600A1/fr unknown
- 1999-01-29 PE PE1999000067A patent/PE20000240A1/es not_active Application Discontinuation
- 1999-01-29 TW TW088101384A patent/TW550069B/zh not_active IP Right Cessation
- 1999-01-30 DZ DZ990015A patent/DZ2714A1/fr active
- 1999-01-31 GC GCP199973 patent/GC0000096A/xx active
- 1999-07-02 US US09/345,009 patent/US6193992B1/en not_active Expired - Fee Related
2000
- 2000-07-27 NO NO20003845A patent/NO319821B1/no unknown
- 2000-07-27 IL IL137569A patent/IL137569A/en unknown
- 2000-08-28 BG BG104715A patent/BG64667B1/bg unknown
2001
- 2001-07-20 GT GT199900013A patent/GT199900013A/es unknown

Also Published As

Publication number	Publication date
GC0000096A (en)	2005-06-29
NZ506597A (en)	2003-07-25
EP1056419A4 (fr)	2007-05-02
JO2085B1 (en)	2000-05-21
TR200002220T2 (tr)	2000-12-21
AR017976A1 (es)	2001-10-24
HUP0101268A2 (hu)	2001-09-28
CO4970819A1 (es)	2000-11-07
CN1250221C (zh)	2006-04-12
BG64667B1 (bg)	2005-11-30
KR20010040477A (ko)	2001-05-15
GT199900013A (es)	2001-07-20
AU752928B2 (en)	2002-10-03
JP2002501875A (ja)	2002-01-22
CR5959A (es)	1999-07-28
TW550069B (en)	2003-09-01
UY25374A1 (es)	1999-09-27
TNSN99008A1 (fr)	2005-11-10
BG104715A (bg)	2001-02-28
IL137569A (en)	2006-08-01
US6193992B1 (en)	2001-02-27
ZA99686B (en)	1999-07-28
HK1040901A1 (en)	2002-06-28
EP1056419A1 (fr)	2000-12-06
PA8467801A1 (es)	2000-09-29
HK1040901B (zh)	2006-11-24
PL342062A1 (en)	2001-05-21
NO20003845L (no)	2000-09-28
HN1999000015A (es)	1999-08-23
WO1999038467A1 (fr)	1999-08-05
CN1313742A (zh)	2001-09-19
NO20003845D0 (no)	2000-07-27
PE20000240A1 (es)	2000-03-31
BR9908038A (pt)	2002-01-02
IL137569A0 (en)	2001-07-24
US5945117A (en)	1999-08-31
PL194350B1 (pl)	2007-05-31
AU2564499A (en)	1999-08-16
HUP0101268A3 (en)	2002-12-28
NO319821B1 (no)	2005-09-19
MA26600A1 (fr)	2004-12-20
DZ2714A1 (fr)	2003-09-01
MXPA00007447A (es)	2006-01-25
CA2322289A1 (fr)	1999-08-05

Publication	Publication Date	Title
US5945117A (en)	1999-08-31	Treatment of female sexual dysfunction
ES2244418T3 (es)	2005-12-16	Composiciones de apomorfina y sidenalfilo y utilizacion de los mismos para el tratamiento de la disfuncion erectil.
US6756407B2 (en)	2004-06-29	Method and compositions for the treatment or amelioration of female sexual dysfunction
EP0758895B1 (fr)	2000-01-26	Formes galeniques sublinguales contenant de l'apomorphine pour l'utilisation dans le traitement du dysfonctionnement erectile
KR20010101241A (ko)	2001-11-14	남성의 기질적 발기 부전 치료용 약제의 제조시아포모르핀의 용도
AU749703B2 (en)	2002-07-04	Combination therapy for modulating the human sexual response
US20040101484A1 (en)	2004-05-27	Nasal delivery of apomorphine in combination with glycol derivatives
JP2002518435A (ja)	2002-06-25	女性の性機能不全の治療または改善のための方法および組成物
CZ20002755A3 (cs)	2000-12-13	Způsob zlepšení ženské sexuální dysfunkce
MXPA01006105A (es)	2002-05-09	Uso de apomorfina en la elaboracion de un medicamento para el tratamiento de la disfuncion erectil organica en los hombres
HK1014239B (en)	2001-02-09	Sublingual dosage forms containing apomorphine for use in the treatment of erectile dysfunction
HK1025742B (en)	2006-10-13	Sublingual composition containing apomorphine for diagnosing functional impotence