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SI1910287T1 - Postopek za pripravo kristalnega perindoprila - Google Patents

Postopek za pripravo kristalnega perindoprila

Info

Publication number
SI1910287T1
SI1910287T1 SI200631349T SI200631349T SI1910287T1 SI 1910287 T1 SI1910287 T1 SI 1910287T1 SI 200631349 T SI200631349 T SI 200631349T SI 200631349 T SI200631349 T SI 200631349T SI 1910287 T1 SI1910287 T1 SI 1910287T1
Authority
SI
Slovenia
Prior art keywords
preparation
perindopril
crystalline perindopril
crystalline
relates
Prior art date
Application number
SI200631349T
Other languages
English (en)
Inventor
Branko Jenko
Anton Copar
Original Assignee
Lek Pharmaceuticals D.D.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lek Pharmaceuticals D.D. filed Critical Lek Pharmaceuticals D.D.
Publication of SI1910287T1 publication Critical patent/SI1910287T1/sl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/06026—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atom, i.e. Gly or Ala
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Hospice & Palliative Care (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
SI200631349T 2005-07-25 2006-07-24 Postopek za pripravo kristalnega perindoprila SI1910287T1 (sl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SI200500214 2005-07-25
PCT/EP2006/007258 WO2007017087A1 (en) 2005-07-25 2006-07-24 Process for the preparation of crystalline perindopril
EP06776370A EP1910287B1 (en) 2005-07-25 2006-07-24 Process for the preparation of crystalline perindopril

Publications (1)

Publication Number Publication Date
SI1910287T1 true SI1910287T1 (sl) 2012-09-28

Family

ID=37451139

Family Applications (1)

Application Number Title Priority Date Filing Date
SI200631349T SI1910287T1 (sl) 2005-07-25 2006-07-24 Postopek za pripravo kristalnega perindoprila

Country Status (14)

Country Link
US (1) US7923570B2 (sl)
EP (1) EP1910287B1 (sl)
JP (1) JP4972643B2 (sl)
CN (1) CN101228126B (sl)
AT (1) ATE549315T1 (sl)
AU (1) AU2006278866B2 (sl)
BR (1) BRPI0613976A2 (sl)
CA (1) CA2615691C (sl)
EA (1) EA013018B1 (sl)
MX (1) MX2008001151A (sl)
SI (1) SI1910287T1 (sl)
UA (1) UA92752C2 (sl)
WO (1) WO2007017087A1 (sl)
ZA (1) ZA200800138B (sl)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2008002066A (es) * 2005-08-12 2008-04-16 Sandoz Ag Neuva forma cristalina de perindopril-erbumina.
UA92613C2 (ru) * 2005-08-12 2010-11-25 Лек Фармасьютиклз Д.Д. Способ получения кристаллической формы d эрбумина периндоприла
SI22543A (sl) 2007-06-27 2008-12-31 Krka, Tovarna Zdravil, D.D., Novo Mesto Nove soli perindoprila
GB0910692D0 (en) * 2009-06-20 2009-08-05 Teva Pharma Compound
CN111116709B (zh) * 2019-12-31 2022-06-24 北京鑫开元医药科技有限公司 一种培哚普利制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2620709B1 (fr) * 1987-09-17 1990-09-07 Adir Procede de synthese industrielle du perindopril et de ses principaux intermediaires de synthese
US20020107230A1 (en) * 2000-12-22 2002-08-08 Waldon R. Forrest Methods and formulations for the treatment of female sexual dysfunction
GB2395195A (en) * 2002-11-18 2004-05-19 Cipla Ltd Preparation of perindopril from carboxy-protected precursor, & perindopril monohydrates for use as angiotensin converting enzyme (ACE) inhibitors
WO2005019173A1 (en) * 2003-08-21 2005-03-03 Hetero Drugs Limited Process for pure perindopril tert-butylamine salt
SI21704A (en) * 2004-01-14 2005-08-31 Lek Farmacevtska Druzba Dd New crystal form of perindopril, procedure of its preparation, pharmaceutical preparations containing this form and their application in treatment of hypertensia

Also Published As

Publication number Publication date
BRPI0613976A2 (pt) 2011-02-22
JP4972643B2 (ja) 2012-07-11
AU2006278866A1 (en) 2007-02-15
WO2007017087A1 (en) 2007-02-15
MX2008001151A (es) 2008-03-13
JP2009502833A (ja) 2009-01-29
EA013018B1 (ru) 2010-02-26
EP1910287B1 (en) 2012-03-14
CA2615691C (en) 2015-11-10
CN101228126A (zh) 2008-07-23
ATE549315T1 (de) 2012-03-15
UA92752C2 (ru) 2010-12-10
ZA200800138B (en) 2009-08-26
US20080306135A1 (en) 2008-12-11
US7923570B2 (en) 2011-04-12
CN101228126B (zh) 2011-10-19
EA200800200A1 (ru) 2008-06-30
AU2006278866B2 (en) 2012-03-15
CA2615691A1 (en) 2007-02-15
EP1910287A1 (en) 2008-04-16

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