SI1666033T1 - Preprečevanje in zdravljenje s pomankanjem androgena inducirane osteoporoze - Google Patents

Preprečevanje in zdravljenje s pomankanjem androgena inducirane osteoporoze

Info

Publication number: SI1666033T1
Authority: SI; Slovenia
Prior art keywords: androgen; deprivation induced; prevention; treatment; induced osteoporosis
Prior art date: 2001-11-29

Application number

SI200230801T

Other languages

English (en)

Inventor

Mitchell S Steiner

Sharan Raghow

Karen A Veverka

Original Assignee

Gtx Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-11-29

Filing date

2002-11-27

Publication date

2009-06-30

2002-11-27 Application filed by Gtx Inc filed Critical Gtx Inc

2009-06-30 Publication of SI1666033T1 publication Critical patent/SI1666033T1/sl

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/01—Hydrocarbons
- A61K31/015—Hydrocarbons carbocyclic
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/02—Halogenated hydrocarbons
- A61K31/025—Halogenated hydrocarbons carbocyclic
- A61K31/03—Halogenated hydrocarbons carbocyclic aromatic
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/26—Androgens
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/30—Oestrogens
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/32—Antioestrogens

Landscapes

Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
General Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Epidemiology (AREA)
Physical Education & Sports Medicine (AREA)
Endocrinology (AREA)
Diabetes (AREA)
Rheumatology (AREA)
Orthopedic Medicine & Surgery (AREA)
Gynecology & Obstetrics (AREA)
Urology & Nephrology (AREA)
Reproductive Health (AREA)
Emergency Medicine (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicinal Preparation (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Steroid Compounds (AREA)

SI200230801T 2001-11-29 2002-11-27 Preprečevanje in zdravljenje s pomankanjem androgena inducirane osteoporoze SI1666033T1 (sl)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US33373401P	2001-11-29	2001-11-29
EP05028100A EP1666033B1 (en)	2001-11-29	2002-11-27	Prevention and treatment of androgen-deprivation induced osteoporosis

Publications (1)

Publication Number	Publication Date
SI1666033T1 true SI1666033T1 (sl)	2009-06-30

Family

ID=23304031

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
SI200230801T SI1666033T1 (sl)	2001-11-29	2002-11-27	Preprečevanje in zdravljenje s pomankanjem androgena inducirane osteoporoze
SI200230705T SI1460969T1 (sl)	2001-11-29	2002-11-27	Preprečevanje in zdravljenje s pomanjkanjem androgena inducirane osteoporoze

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
SI200230705T SI1460969T1 (sl)	2001-11-29	2002-11-27	Preprečevanje in zdravljenje s pomanjkanjem androgena inducirane osteoporoze

Country Status (22)

Country	Link
US (1)	US6899888B2 (sl)
EP (5)	EP2098247A3 (sl)
JP (2)	JP2005515988A (sl)
KR (1)	KR100658110B1 (sl)
CN (2)	CN100548283C (sl)
AT (2)	ATE418972T1 (sl)
AU (2)	AU2002356928B2 (sl)
BR (1)	BR0214801A (sl)
CA (2)	CA2468719C (sl)
CY (2)	CY1108174T1 (sl)
DE (2)	DE60230687D1 (sl)
DK (2)	DK1666033T3 (sl)
EA (1)	EA200400744A1 (sl)
ES (2)	ES2319785T3 (sl)
GE (1)	GEP20094841B (sl)
HR (1)	HRP20040547A2 (sl)
IL (2)	IL162144A0 (sl)
MX (1)	MXPA04005112A (sl)
PT (2)	PT1666033E (sl)
SI (2)	SI1666033T1 (sl)
TW (1)	TWI315987B (sl)
WO (1)	WO2003047504A2 (sl)

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US7622503B2 (en) *	2000-08-24	2009-11-24	University Of Tennessee Research Foundation	Selective androgen receptor modulators and methods of use thereof
US20050080143A1 (en) *	2001-11-29	2005-04-14	Steiner Mitchell S.	Treatment of androgen-deprivation induced osteoporosis
US20080249183A1 (en) *	2001-11-29	2008-10-09	Steiner Mitchell S	Treatment of androgen-deprivation induced osteoporosis
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US20070197664A1 (en) *	2001-11-29	2007-08-23	Steiner Mitchell S	Prevention and treatment of androgen-deprivation induced osteoporosis
US20060269611A1 (en) *	2001-11-29	2006-11-30	Steiner Mitchell S	Prevention and treatment of androgen-deprivation induced osteoporosis
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US9884038B2 (en)	2004-06-07	2018-02-06	University Of Tennessee Research Foundation	Selective androgen receptor modulator and methods of use thereof
US9889110B2 (en)	2004-06-07	2018-02-13	University Of Tennessee Research Foundation	Selective androgen receptor modulator for treating hormone-related conditions
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US8546451B2 (en)	2005-11-28	2013-10-01	Gtx, Inc.	Estrogen receptor ligands and methods of use thereof
WO2008099060A2 (en)	2007-02-14	2008-08-21	Hormos Medical Ltd	Methods for the preparation of fispemifene from ospemifene
BRPI0807675B1 (pt)	2007-02-14	2021-05-18	Hormos Medical Ltd.	método para a preparação de um composto derivado de trifenilbuteno
US7968603B2 (en)	2007-09-11	2011-06-28	University Of Tennessee Research Foundation	Solid forms of selective androgen receptor modulators
CN104188971B (zh) *	2007-12-21	2017-05-03	配体药物公司	选择性雄激素受体调节剂(sarm)及其应用
US9624161B2 (en)	2009-02-23	2017-04-18	Gtx, Inc.	Estrogen receptor ligands and methods of use thereof
US9427418B2 (en)	2009-02-23	2016-08-30	Gtx, Inc.	Estrogen receptor ligands and methods of use thereof
US10258596B2 (en)	2012-07-13	2019-04-16	Gtx, Inc.	Method of treating HER2-positive breast cancers with selective androgen receptor modulators (SARMS)
US9969683B2 (en)	2012-07-13	2018-05-15	Gtx, Inc.	Method of treating estrogen receptor (ER)-positive breast cancers with selective androgen receptor modulator (SARMS)
US9744149B2 (en)	2012-07-13	2017-08-29	Gtx, Inc.	Method of treating androgen receptor (AR)-positive breast cancers with selective androgen receptor modulator (SARMs)
US9622992B2 (en)	2012-07-13	2017-04-18	Gtx, Inc.	Method of treating androgen receptor (AR)-positive breast cancers with selective androgen receptor modulator (SARMs)
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US10314807B2 (en)	2012-07-13	2019-06-11	Gtx, Inc.	Method of treating HER2-positive breast cancers with selective androgen receptor modulators (SARMS)
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2002
- 2002-11-27 DE DE60230687T patent/DE60230687D1/de not_active Expired - Lifetime
- 2002-11-27 ES ES05028100T patent/ES2319785T3/es not_active Expired - Lifetime
- 2002-11-27 PT PT05028100T patent/PT1666033E/pt unknown
- 2002-11-27 MX MXPA04005112A patent/MXPA04005112A/es active IP Right Grant
- 2002-11-27 DK DK05028100T patent/DK1666033T3/da active
- 2002-11-27 CN CNB028276930A patent/CN100548283C/zh not_active Expired - Fee Related
- 2002-11-27 JP JP2003548765A patent/JP2005515988A/ja active Pending
- 2002-11-27 EP EP08172485A patent/EP2098247A3/en not_active Withdrawn
- 2002-11-27 WO PCT/US2002/036136 patent/WO2003047504A2/en not_active Ceased
- 2002-11-27 IL IL16214402A patent/IL162144A0/xx unknown
- 2002-11-27 AT AT05028100T patent/ATE418972T1/de active
- 2002-11-27 DK DK02804417T patent/DK1460969T3/da active
- 2002-11-27 SI SI200230801T patent/SI1666033T1/sl unknown
- 2002-11-27 CA CA2468719A patent/CA2468719C/en not_active Expired - Fee Related
- 2002-11-27 HR HR20040547A patent/HRP20040547A2/xx not_active Application Discontinuation
- 2002-11-27 CA CA002537913A patent/CA2537913A1/en not_active Abandoned
- 2002-11-27 US US10/305,363 patent/US6899888B2/en not_active Expired - Fee Related
- 2002-11-27 EP EP02804417A patent/EP1460969B1/en not_active Expired - Lifetime
- 2002-11-27 BR BR0214801-3A patent/BR0214801A/pt not_active Application Discontinuation
- 2002-11-27 CN CNA2005100638704A patent/CN1679956A/zh active Pending
- 2002-11-27 DE DE60226494T patent/DE60226494D1/de not_active Expired - Lifetime
- 2002-11-27 KR KR1020047008234A patent/KR100658110B1/ko not_active Expired - Fee Related
- 2002-11-27 EP EP05006610A patent/EP1574212A1/en not_active Withdrawn
- 2002-11-27 AT AT02804417T patent/ATE394099T1/de active
- 2002-11-27 ES ES02804417T patent/ES2305350T3/es not_active Expired - Lifetime
- 2002-11-27 PT PT02804417T patent/PT1460969E/pt unknown
- 2002-11-27 GE GEAP20028274A patent/GEP20094841B/en unknown
- 2002-11-27 EP EP07111247A patent/EP1862165A3/en not_active Withdrawn
- 2002-11-27 EP EP05028100A patent/EP1666033B1/en not_active Expired - Lifetime
- 2002-11-27 AU AU2002356928A patent/AU2002356928B2/en not_active Ceased
- 2002-11-27 SI SI200230705T patent/SI1460969T1/sl unknown
- 2002-11-27 EA EA200400744A patent/EA200400744A1/ru unknown
- 2002-12-16 TW TW091136262A patent/TWI315987B/zh not_active IP Right Cessation
2005
- 2005-04-07 JP JP2005110874A patent/JP2005247862A/ja active Pending
2008
- 2008-07-03 CY CY20081100699T patent/CY1108174T1/el unknown
- 2008-07-15 AU AU2008203121A patent/AU2008203121A1/en not_active Abandoned
2009
- 2009-03-23 CY CY20091100318T patent/CY1108895T1/el unknown
2010
- 2010-06-27 IL IL206646A patent/IL206646A0/en unknown

Also Published As

Publication number	Publication date
AU2002356928B2 (en)	2008-04-17
HRP20040547A2 (en)	2005-08-31
EA200400744A1 (ru)	2005-02-24
DE60230687D1 (de)	2009-02-12
CY1108174T1 (el)	2014-02-12
DK1460969T3 (da)	2008-09-01
EP1574212A1 (en)	2005-09-14
IL162144A0 (en)	2005-11-20
TWI315987B (en)	2009-10-21
DK1666033T3 (da)	2009-04-06
ES2305350T3 (es)	2008-11-01
EP1666033B1 (en)	2008-12-31
AU2002356928A1 (en)	2003-06-17
CN100548283C (zh)	2009-10-14
TW200410711A (en)	2004-07-01
BR0214801A (pt)	2005-01-11
KR20050044618A (ko)	2005-05-12
ATE418972T1 (de)	2009-01-15
MXPA04005112A (es)	2005-04-29
WO2003047504A3 (en)	2003-10-16
PT1666033E (pt)	2009-02-09
DE60226494D1 (de)	2008-06-19
ES2319785T3 (es)	2009-05-12
US6899888B2 (en)	2005-05-31
CN1679956A (zh)	2005-10-12
EP1460969B1 (en)	2008-05-07
CA2468719A1 (en)	2003-06-12
HK1068104A1 (en)	2005-04-22
PT1460969E (pt)	2008-07-01
CA2468719C (en)	2011-05-24
ATE394099T1 (de)	2008-05-15
AU2008203121A1 (en)	2008-08-07
US20030153625A1 (en)	2003-08-14
EP1862165A3 (en)	2008-06-25
JP2005247862A (ja)	2005-09-15
IL206646A0 (en)	2011-07-31
KR100658110B1 (ko)	2006-12-14
EP1460969A4 (en)	2005-08-17
EP1862165A2 (en)	2007-12-05
EP2098247A3 (en)	2010-05-26
EP1460969A2 (en)	2004-09-29
WO2003047504A2 (en)	2003-06-12
HK1092066A1 (en)	2007-02-02
CN1617691A (zh)	2005-05-18
EP1666033A1 (en)	2006-06-07
JP2005515988A (ja)	2005-06-02
GEP20094841B (en)	2009-11-25
EP2098247A2 (en)	2009-09-09
CA2537913A1 (en)	2003-06-12
CY1108895T1 (el)	2014-07-02
SI1460969T1 (sl)	2008-10-31

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