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SI0758644T1 - Sulfonyl- or sulfinyl-benzoyl-guanidine derivatives - Google Patents

Sulfonyl- or sulfinyl-benzoyl-guanidine derivatives

Info

Publication number
SI0758644T1
SI0758644T1 SI9630659T SI9630659T SI0758644T1 SI 0758644 T1 SI0758644 T1 SI 0758644T1 SI 9630659 T SI9630659 T SI 9630659T SI 9630659 T SI9630659 T SI 9630659T SI 0758644 T1 SI0758644 T1 SI 0758644T1
Authority
SI
Slovenia
Prior art keywords
sulfinyl
sulfonyl
benzoyl
guanidine derivatives
guanidine
Prior art date
Application number
SI9630659T
Other languages
English (en)
Slovenian (sl)
Inventor
Rolf Dr. Gericke
Manfred Dr. Baumgarth
Klaus-Otto Dr. Minck
Norbert Dr. Beier
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=7769293&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SI0758644(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of SI0758644T1 publication Critical patent/SI0758644T1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00—Sulfones; Sulfoxides
    • C07C317/26—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
    • C07C317/32—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton with sulfone or sulfoxide groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
    • C07C317/34—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton with sulfone or sulfoxide groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton having sulfone or sulfoxide groups and amino groups bound to carbon atoms of six-membered aromatic rings being part of the same non-condensed ring or of a condensed ring system containing that ring
    • C07C317/38—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton with sulfone or sulfoxide groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton having sulfone or sulfoxide groups and amino groups bound to carbon atoms of six-membered aromatic rings being part of the same non-condensed ring or of a condensed ring system containing that ring with the nitrogen atom of at least one amino group being part of any of the groups, X being a hetero atom, Y being any atom, e.g. N-acylaminosulfones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00—Sulfones; Sulfoxides
    • C07C317/44—Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Endocrinology (AREA)
  • Urology & Nephrology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Emergency Medicine (AREA)
  • Vascular Medicine (AREA)
  • Obesity (AREA)
  • Pulmonology (AREA)
  • Reproductive Health (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Measuring Leads Or Probes (AREA)
SI9630659T 1995-08-11 1996-08-02 Sulfonyl- or sulfinyl-benzoyl-guanidine derivatives SI0758644T1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19529612A DE19529612A1 (de) 1995-08-11 1995-08-11 Sulfonyl- oder Sulfinyl-benzoylguanidin-Derivate
EP96112498A EP0758644B1 (de) 1995-08-11 1996-08-02 Sulfonyl- oder Sulfinyl-benzoyl-guanidin-Derivate

Publications (1)

Publication Number Publication Date
SI0758644T1 true SI0758644T1 (en) 2004-04-30

Family

ID=7769293

Family Applications (1)

Application Number Title Priority Date Filing Date
SI9630659T SI0758644T1 (en) 1995-08-11 1996-08-02 Sulfonyl- or sulfinyl-benzoyl-guanidine derivatives

Country Status (25)

Country Link
US (1) US5744641A (no)
EP (1) EP0758644B1 (no)
JP (1) JP3901766B2 (no)
KR (1) KR100447111B1 (no)
CN (1) CN1071743C (no)
AR (1) AR004677A1 (no)
AT (1) ATE252075T1 (no)
AU (1) AU709800B2 (no)
BR (1) BR9603377B1 (no)
CA (1) CA2183050C (no)
CZ (1) CZ292974B6 (no)
DE (2) DE19529612A1 (no)
DK (1) DK0758644T3 (no)
ES (1) ES2206534T3 (no)
HU (1) HU226134B1 (no)
MX (1) MX9603300A (no)
NO (1) NO306858B1 (no)
PL (1) PL184320B1 (no)
PT (1) PT758644E (no)
RU (1) RU2159232C2 (no)
SI (1) SI0758644T1 (no)
SK (1) SK281661B6 (no)
TW (1) TW432039B (no)
UA (1) UA45965C2 (no)
ZA (1) ZA966773B (no)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4328352A1 (de) 1993-08-24 1995-03-02 Hoechst Ag Substituierte N,N'-Di-benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament
DE19833118C2 (de) * 1998-07-23 2000-07-27 Merck Patent Gmbh Verfahren zur Herstellung von orthoalkylierten Benzoesäurederivaten
DE19903275A1 (de) * 1999-01-28 2000-08-03 Merck Patent Gmbh Lyophilisate mit verbesserter Rekonstituierbarkeit
DE19951418A1 (de) * 1999-10-26 2001-05-03 Merck Patent Gmbh Verfahren zur Herstellung von N-(4,5-Bismethansulfonyl-2-methyl-benzoyl) -guanidin, Hydrochlorid
DE10001879A1 (de) * 2000-01-19 2001-07-19 Aventis Pharma Gmbh Substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament
DE10023405A1 (de) 2000-05-12 2001-11-15 Merck Patent Gmbh Verfahren zur Herstellung von Sulfonyl-benzoylguanidinum-Salzen
KR100643561B1 (ko) * 2000-12-08 2006-11-10 엘지.필립스 엘시디 주식회사 액정표시장치용 어레이기판과 어레이기판의 제조방법
DE10305070A1 (de) * 2003-02-07 2004-08-26 Merck Patent Gmbh Verwendung von N-(4,5-Methansulfonyl-2-methyl-benzoyl)-guanidin
AU2004235886B2 (en) * 2003-05-06 2010-07-01 Merck Patent Gmbh Method for crystallizing guanidinium salts
DE102004045825A1 (de) * 2004-09-22 2006-03-23 Merck Patent Gmbh Lyophilisat enthaltend N-Diaminomethylen-2-methyl-4,5-di-(methylsulfonyl)-benzamid
JP5634985B2 (ja) * 2008-05-09 2014-12-03 メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツングＭｅｒｃｋ Ｐａｔｅｎｔ Ｇｅｓｅｌｌｓｃｈａｆｔ ｍｉｔ ｂｅｓｃｈｒａｅｎｋｔｅｒ Ｈａｆｔｕｎｇ インスリン抵抗性およびβ−細胞機能障害に関連する疾患を治療するためのリメポリドを含む医薬組成物
KR20110050718A (ko) * 2008-09-02 2011-05-16 사노피-아벤티스 치환된 아미노인단 및 그의 유사체, 및 그의 제약 용도
FR2948028B1 (fr) 2009-07-17 2011-12-02 Merck Sante Sas Association d'un inhibiteur de l'echangeur sodium-proton et d'un derive amine de dihydro-1,3,5-triazine
CN108602767A (zh) * 2016-02-08 2018-09-28 默克专利股份有限公司 N-(4,5-双甲磺酰基-2-甲基苯甲酰基)胍盐酸盐和n-(4,5-双甲磺酰基-2-甲基苯甲酰基)胍盐的结晶变体
EP4230196A1 (en) 2022-02-21 2023-08-23 Som Innovation Biotech, S.A. Compounds for use in the treatment of dystrophinopathies

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU616041B2 (en) * 1988-08-26 1991-10-17 Sumitomo Chemical Company, Limited A hydrazone compound and production therefor, and an insecticidal composition containing the same
DE3929582A1 (de) * 1989-09-06 1991-03-07 Hoechst Ag Benzoylguanidine, verfahren zu ihrer herstellung, ihre verwendung als medikament sowie sie enthaltendes medikament
ATE147375T1 (de) * 1992-09-22 1997-01-15 Hoechst Ag Benzoylguanidine, verfahren zu ihrer herstellung, sowie ihre verwendung als antiarrhythmika
EP0604852A1 (de) * 1992-12-28 1994-07-06 Hoechst Aktiengesellschaft 2,4-Substituierte 5-(N-substituierte-Sulfamoyl)-Benzoylguanidine, als Antiarrythmika, Inhibitoren der Proliferationen von Zellen, und Inhibitoren des Natrium-Protonen-Antiporters
DE4430916A1 (de) * 1994-08-31 1996-03-07 Merck Patent Gmbh Alkyl-benzoylguanidin-Derivate

Also Published As

Publication number Publication date
TW432039B (en) 2001-05-01
HU226134B1 (en) 2008-05-28
NO306858B1 (no) 2000-01-03
NO963340L (no) 1997-02-12
DE59610773D1 (de) 2003-11-20
BR9603377B1 (pt) 2009-01-13
EP0758644A1 (de) 1997-02-19
PT758644E (pt) 2004-02-27
JPH0952876A (ja) 1997-02-25
HUP9602196A2 (en) 1997-05-28
AU709800B2 (en) 1999-09-09
CN1148590A (zh) 1997-04-30
MX9603300A (es) 1997-03-29
ZA966773B (en) 1997-02-19
EP0758644B1 (de) 2003-10-15
SK103396A3 (en) 1997-03-05
CZ231296A3 (en) 1997-02-12
NO963340D0 (no) 1996-08-09
ATE252075T1 (de) 2003-11-15
DE19529612A1 (de) 1997-02-13
UA45965C2 (uk) 2002-05-15
CA2183050C (en) 2008-09-30
AR004677A1 (es) 1999-03-10
BR9603377A (pt) 1998-05-12
SK281661B6 (sk) 2001-06-11
ES2206534T3 (es) 2004-05-16
CZ292974B6 (cs) 2004-01-14
PL315611A1 (en) 1997-02-17
AU6191796A (en) 1997-02-13
CN1071743C (zh) 2001-09-26
PL184320B1 (pl) 2002-10-31
KR100447111B1 (ko) 2004-12-08
KR970010740A (ko) 1997-03-27
RU2159232C2 (ru) 2000-11-20
HUP9602196A3 (en) 1998-07-28
US5744641A (en) 1998-04-28
CA2183050A1 (en) 1997-02-12
DK0758644T3 (da) 2003-12-22
JP3901766B2 (ja) 2007-04-04
HU9602196D0 (en) 1996-10-28

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