SG11201610813TA - Histone demethylase inhibitors - Google Patents

Histone demethylase inhibitors

Info

Publication number: SG11201610813TA
Authority: SG; Singapore
Prior art keywords: histone demethylase; demethylase inhibitors; inhibitors; histone; demethylase
Prior art date: 2014-06-25

Application number

SG11201610813TA

Inventor

Young K Chen

Michael Brennan Wallace

Amogh Boloor

Original Assignee

Quanticel Pharmaceuticals Inc

Amogh Boloor

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2014-06-25

Filing date

2015-06-25

Publication date

2017-01-27

2015-06-25 Application filed by Quanticel Pharmaceuticals Inc, Amogh Boloor filed Critical Quanticel Pharmaceuticals Inc

2017-01-27 Publication of SG11201610813TA publication Critical patent/SG11201610813TA/en

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4433—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with oxygen as a ring hetero atom
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/79—Acids; Esters
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Epidemiology (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Pyridine Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Enzymes And Modification Thereof (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Immobilizing And Processing Of Enzymes And Microorganisms (AREA)

SG11201610813TA 2014-06-25 2015-06-25 Histone demethylase inhibitors SG11201610813TA (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US201462017201P	2014-06-25	2014-06-25
PCT/US2015/037812 WO2015200709A1 (en)	2014-06-25	2015-06-25	Histone demethylase inhibitors

Publications (1)

Publication Number	Publication Date
SG11201610813TA true SG11201610813TA (en)	2017-01-27

Family

ID=54929774

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
SG11201610813TA SG11201610813TA (en)	2014-06-25	2015-06-25	Histone demethylase inhibitors

Country Status (29)

Country	Link
US (7)	US9242968B2 (en)
EP (3)	EP3160952B1 (en)
JP (1)	JP6521535B2 (en)
KR (1)	KR102591897B1 (en)
CN (2)	CN106660982B (en)
AR (1)	AR100997A1 (en)
AU (1)	AU2015279719B2 (en)
BR (1)	BR112016030367A2 (en)
CA (1)	CA2953437C (en)
CL (1)	CL2016003301A1 (en)
CO (1)	CO2017000359A2 (en)
CY (1)	CY1123906T1 (en)
DK (1)	DK3160952T3 (en)
EA (1)	EA031200B1 (en)
EC (1)	ECSP17004931A (en)
ES (1)	ES2862648T3 (en)
HR (1)	HRP20210299T1 (en)
HU (1)	HUE053876T2 (en)
IL (1)	IL249629A0 (en)
LT (1)	LT3160952T (en)
MX (1)	MX375219B (en)
NZ (1)	NZ728120A (en)
PL (1)	PL3160952T3 (en)
PT (1)	PT3160952T (en)
SA (1)	SA516380585B1 (en)
SG (1)	SG11201610813TA (en)
SI (1)	SI3160952T1 (en)
TW (2)	TWI715533B (en)
WO (1)	WO2015200709A1 (en)

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CA2895808A1 (en)	2012-12-21	2014-06-26	Quanticel Pharmaceuticals, Inc.	Histone demethylase inhibitors
MX375219B (en)	2014-06-25	2025-03-06	Celgene Quanticel Res Inc	HISTONE DEMETHYLASE INHIBITORS.
US10030017B2 (en)	2014-09-17	2018-07-24	Celgene Quanticel Research, Inc.	Histone demethylase inhibitors
BR112017005511A2 (en)	2014-09-17	2018-08-14	Celgene Quanticel Res Inc	histone demethylase inhibitors.
JP6883913B2 (en) *	2015-12-28	2021-06-09	セルジーンクオンティセルリサーチ，インク．	Histone demethylase inhibitor
EP3430008B1 (en) *	2016-03-15	2022-05-18	Celgene Quanticel Research, Inc.	Histone demethylase inhibitors
US10150754B2 (en)	2016-04-19	2018-12-11	Celgene Quanticel Research, Inc.	Histone demethylase inhibitors
JP7442439B2 (en) *	2017-03-30	2024-03-04	アルベルト－ルートヴィヒ－ユニバーシティーフライブルク	KDM4 inhibitor
CN109825551B (en) *	2019-02-21	2022-08-02	深圳大学	A method for evaluating histone lysine demethyltransferase activity
CN111679072B (en) *	2020-06-15	2022-04-29	温州医科大学	Application of KDM6B protein in breast cancer prognosis assessment kits and diagnostic kits
US20250025451A1 (en) *	2021-04-09	2025-01-23	Celgene Corporation	Treatment of cancer with kdm4 inhibitors
WO2023023112A1 (en) *	2021-08-18	2023-02-23	Celgene Corporation	Process for preparing histone demethylase inhibitors
EP4452249A1 (en) *	2021-12-23	2024-10-30	Tachyon Therapeutics, Inc.	Pharmaceutical formulations comprising 3-({[(4r)-7-{methyl[4-(propan-2-yl)phenyl]amino}-3,4-dihydro-2h-l-benzopyran-4-yl]methyl}amino)pyridine-4-carboxylic acid
TW202412816A (en)	2022-06-10	2024-04-01	美商弗沃德醫療公司	MODULATORS OF TNF-α ACTIVITY
EP4543437A1 (en) *	2022-06-23	2025-04-30	The Cleveland Clinic Foundation	3-?hsd1 inhibitors and compositions and uses thereof
JP2025532101A (en) *	2022-09-21	2025-09-29	セルジーンコーポレーション	L-lysine salt of 3-({[(4R)-7-{methyl[4-(propan-2-yl)phenyl]amino}-3,4-dihydro-2H-1-benzopyran-4-yl]methyl}amino)pyridine-4-carboxylic acid, a histone demethylase inhibitor
CN115974647B (en) *	2022-12-05	2024-09-03	江苏宏邦化工科技有限公司	Method for preparing cola amyl alcohol by taking tetrahydro-4-methyl-2-phenyl-2H-pyran-4-alcohol as raw material
WO2025085527A1 (en) *	2023-10-16	2025-04-24	The Cleveland Clinic Foundation	3βHSD1 INHIBITORS AND COMPOSITIONS AND USES THEREOF

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CA2465978C (en)	2001-09-14	2015-04-07	Soon Hyung Woo	Inhibitors of histone deacetylase
UA89035C2 (en)	2003-12-03	2009-12-25	Лео Фарма А/С	Hydroxamic acid esters and pharmaceutical use thereof
DE102004039876A1 (en)	2004-06-23	2006-01-26	Lanxess Deutschland Gmbh	Preparation of fluorinated 1,3-benzodioxanes
PE20071020A1 (en)	2006-03-07	2007-12-11	Smithkline Beecham Corp	N-SUBSTITUTED GLYCINE DERIVATIVE COMPOUNDS AS PROLYL HYDROXYLASE INHIBITORS
KR101495611B1 (en) *	2006-04-07	2015-02-25	메틸진 인코포레이티드	Inhibitors of histone deacetylase
US7898712B2 (en)	2008-06-27	2011-03-01	Lockheed Martin Corporation	Risley integrated steering module
GB201112607D0 (en) *	2011-07-22	2011-09-07	Glaxo Group Ltd	Novel compounds
EP2701699B1 (en) *	2011-04-28	2019-10-16	The Broad Institute, Inc.	Inhibitors of histone deacetylase
WO2013143597A1 (en) *	2012-03-29	2013-10-03	Glaxo Group Limited	Demethylase enzymes inhibitors
US20140162266A1 (en)	2012-12-05	2014-06-12	Bio-Rad Laboratories, Inc.	Methods for polymerase chain reaction copy number variation assays
EP3763367A1 (en) *	2012-12-06	2021-01-13	Celgene Quanticel Research, Inc.	Pyridine-pyrazole derivatives as histone demethylase inhibitors
RS56821B1 (en)	2012-12-19	2018-04-30	Celgene Quanticel Research Inc	Histone demethylase inhibitors
CA2895808A1 (en) *	2012-12-21	2014-06-26	Quanticel Pharmaceuticals, Inc.	Histone demethylase inhibitors
MX375219B (en)	2014-06-25	2025-03-06	Celgene Quanticel Res Inc	HISTONE DEMETHYLASE INHIBITORS.
JP7442439B2 (en) *	2017-03-30	2024-03-04	アルベルト－ルートヴィヒ－ユニバーシティーフライブルク	KDM4 inhibitor

2015
- 2015-06-25 MX MX2016017407A patent/MX375219B/en active IP Right Grant
- 2015-06-25 CA CA2953437A patent/CA2953437C/en active Active
- 2015-06-25 SI SI201531524T patent/SI3160952T1/en unknown
- 2015-06-25 ES ES15811523T patent/ES2862648T3/en active Active
- 2015-06-25 US US14/751,007 patent/US9242968B2/en active Active
- 2015-06-25 BR BR112016030367A patent/BR112016030367A2/en not_active Application Discontinuation
- 2015-06-25 EA EA201692483A patent/EA031200B1/en unknown
- 2015-06-25 NZ NZ728120A patent/NZ728120A/en unknown
- 2015-06-25 HR HRP20210299TT patent/HRP20210299T1/en unknown
- 2015-06-25 AR ARP150102042A patent/AR100997A1/en not_active Application Discontinuation
- 2015-06-25 TW TW104120633A patent/TWI715533B/en active
- 2015-06-25 CN CN201580045921.2A patent/CN106660982B/en active Active
- 2015-06-25 TW TW109143458A patent/TWI758004B/en active
- 2015-06-25 SG SG11201610813TA patent/SG11201610813TA/en unknown
- 2015-06-25 HU HUE15811523A patent/HUE053876T2/en unknown
- 2015-06-25 LT LTEP15811523.8T patent/LT3160952T/en unknown
- 2015-06-25 US US15/321,702 patent/US10385047B2/en active Active
- 2015-06-25 EP EP15811523.8A patent/EP3160952B1/en active Active
- 2015-06-25 AU AU2015279719A patent/AU2015279719B2/en active Active
- 2015-06-25 EP EP20184107.9A patent/EP3738960A1/en not_active Withdrawn
- 2015-06-25 KR KR1020177002223A patent/KR102591897B1/en active Active
- 2015-06-25 PT PT158115238T patent/PT3160952T/en unknown
- 2015-06-25 CN CN202010813617.0A patent/CN111909083B/en active Active
- 2015-06-25 JP JP2016574454A patent/JP6521535B2/en active Active
- 2015-06-25 DK DK15811523.8T patent/DK3160952T3/en active
- 2015-06-25 WO PCT/US2015/037812 patent/WO2015200709A1/en not_active Ceased
- 2015-06-25 EP EP20184106.1A patent/EP3741749A1/en active Pending
- 2015-06-25 PL PL15811523T patent/PL3160952T3/en unknown
- 2015-12-09 US US14/963,754 patent/US9447046B2/en active Active
2016
- 2016-07-26 US US15/220,118 patent/US9586902B2/en active Active
- 2016-12-18 IL IL249629A patent/IL249629A0/en unknown
- 2016-12-22 SA SA516380585A patent/SA516380585B1/en unknown
- 2016-12-22 CL CL2016003301A patent/CL2016003301A1/en unknown
2017
- 2017-01-09 US US15/402,100 patent/US9815828B2/en active Active
- 2017-01-16 CO CONC2017/0000359A patent/CO2017000359A2/en unknown
- 2017-01-24 EC ECIEPI20174931A patent/ECSP17004931A/en unknown
- 2017-10-24 US US15/792,570 patent/US9994561B2/en active Active
2018
- 2018-05-04 US US15/971,749 patent/US10106534B2/en active Active
2021
- 2021-03-01 CY CY20211100169T patent/CY1123906T1/en unknown

Also Published As

Publication number	Publication date
US20170114055A1 (en)	2017-04-27
AU2015279719B2 (en)	2019-03-21
HRP20210299T1 (en)	2021-04-16
ECSP17004931A (en)	2017-03-31
US20170158685A1 (en)	2017-06-08
WO2015200709A1 (en)	2015-12-30
CN106660982A (en)	2017-05-10
US10385047B2 (en)	2019-08-20
EP3160952A4 (en)	2018-02-21
IL249629A0 (en)	2017-02-28
TWI758004B (en)	2022-03-11
EP3160952B1 (en)	2020-12-02
HUE053876T2 (en)	2021-07-28
MX375219B (en)	2025-03-06
SI3160952T1 (en)	2021-07-30
JP6521535B2 (en)	2019-05-29
US20150376169A1 (en)	2015-12-31
AR100997A1 (en)	2016-11-16
EA031200B1 (en)	2018-11-30
US9242968B2 (en)	2016-01-26
CN106660982B (en)	2020-09-08
AU2015279719A1 (en)	2017-02-02
SA516380585B1 (en)	2020-12-06
CO2017000359A2 (en)	2017-04-10
BR112016030367A2 (en)	2018-07-17
PL3160952T3 (en)	2021-07-19
KR20170018079A (en)	2017-02-15
US9994561B2 (en)	2018-06-12
EP3160952A1 (en)	2017-05-03
CL2016003301A1 (en)	2021-03-05
EP3738960A1 (en)	2020-11-18
CA2953437A1 (en)	2015-12-30
DK3160952T3 (en)	2021-03-08
TW201613882A (en)	2016-04-16
EA201692483A1 (en)	2017-05-31
US10106534B2 (en)	2018-10-23
EP3741749A1 (en)	2020-11-25
US9815828B2 (en)	2017-11-14
CY1123906T1 (en)	2022-05-27
US9447046B2 (en)	2016-09-20
MX2016017407A (en)	2017-04-27
JP2017523152A (en)	2017-08-17
CN111909083A (en)	2020-11-10
KR102591897B1 (en)	2023-10-19
ES2862648T3 (en)	2021-10-07
US20180044334A1 (en)	2018-02-15
US9586902B2 (en)	2017-03-07
NZ728120A (en)	2023-06-30
US20160107995A1 (en)	2016-04-21
LT3160952T (en)	2021-05-10
CN111909083B (en)	2023-08-15
TWI715533B (en)	2021-01-11
TW202124369A (en)	2021-07-01
CA2953437C (en)	2022-08-30
PT3160952T (en)	2021-03-08
US20160332970A1 (en)	2016-11-17
US20180251458A1 (en)	2018-09-06

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GB201501004D0 (en)	2015-03-04	Inhibitors
GB201400299D0 (en)	2014-02-26	Corrosion inhibitors
IL251184A0 (en)	2017-05-29	Histone demethylase inhibitors
GB201520949D0 (en)	2016-01-13	Inhibitors
HK1233859A1 (en)	2018-02-09	Histone demethylase inhibitors
HK1233942A1 (en)	2018-02-09	Histone demethylase inhibitors
HK1234046A1 (en)	2018-02-09	Histone demethylase inhibitors
GB201418154D0 (en)	2014-11-26	Inhibitors
GB201400300D0 (en)	2014-02-26	Corrosion inhibitors