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SG11201603044SA - Systems and methods for using paired-end data in directed acyclic structure - Google Patents

Systems and methods for using paired-end data in directed acyclic structure

Info

Publication number
SG11201603044SA
SG11201603044SA SG11201603044SA SG11201603044SA SG11201603044SA SG 11201603044S A SG11201603044S A SG 11201603044SA SG 11201603044S A SG11201603044S A SG 11201603044SA SG 11201603044S A SG11201603044S A SG 11201603044SA SG 11201603044S A SG11201603044S A SG 11201603044SA
Authority
SG
Singapore
Prior art keywords
paired
systems
methods
end data
directed acyclic
Prior art date
Application number
SG11201603044SA
Inventor
Deniz Kural
Nathan Meyvis
Original Assignee
Seven Bridges Genomics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Seven Bridges Genomics Inc filed Critical Seven Bridges Genomics Inc
Publication of SG11201603044SA publication Critical patent/SG11201603044SA/en

Links

Classifications

    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B30/00—ICT specially adapted for sequence analysis involving nucleotides or amino acids
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B30/00—ICT specially adapted for sequence analysis involving nucleotides or amino acids
    • G16B30/10—Sequence alignment; Homology search
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B50/00—ICT programming tools or database systems specially adapted for bioinformatics
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B50/00—ICT programming tools or database systems specially adapted for bioinformatics
    • G16B50/10—Ontologies; Annotations
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics

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  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medical Informatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Biotechnology (AREA)
  • Evolutionary Biology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Theoretical Computer Science (AREA)
  • Databases & Information Systems (AREA)
  • Analytical Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioethics (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Data Mining & Analysis (AREA)
  • Pathology (AREA)
  • Epidemiology (AREA)
  • Primary Health Care (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
SG11201603044SA 2013-10-21 2014-10-15 Systems and methods for using paired-end data in directed acyclic structure SG11201603044SA (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361893467P 2013-10-21 2013-10-21
US14/157,979 US9092402B2 (en) 2013-10-21 2014-01-17 Systems and methods for using paired-end data in directed acyclic structure
PCT/US2014/060690 WO2015061103A1 (en) 2013-10-21 2014-10-15 Systems and methods for using paired-end data in directed acyclic structure

Publications (1)

Publication Number Publication Date
SG11201603044SA true SG11201603044SA (en) 2016-05-30

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201603044SA SG11201603044SA (en) 2013-10-21 2014-10-15 Systems and methods for using paired-end data in directed acyclic structure

Country Status (9)

Country Link
US (4) US9063914B2 (en)
EP (1) EP3061022B1 (en)
JP (1) JP2016539443A (en)
KR (1) KR20160073406A (en)
CN (1) CN105830078B (en)
AU (1) AU2014340461B2 (en)
CA (1) CA2927723C (en)
SG (1) SG11201603044SA (en)
WO (2) WO2015061099A1 (en)

Families Citing this family (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9116866B2 (en) 2013-08-21 2015-08-25 Seven Bridges Genomics Inc. Methods and systems for detecting sequence variants
US9898575B2 (en) 2013-08-21 2018-02-20 Seven Bridges Genomics Inc. Methods and systems for aligning sequences
WO2015058097A1 (en) 2013-10-18 2015-04-23 Seven Bridges Genomics Inc. Methods and systems for identifying disease-induced mutations
CN105793689B (en) 2013-10-18 2020-04-17 七桥基因公司 Methods and systems for genotyping genetic samples
WO2015058120A1 (en) * 2013-10-18 2015-04-23 Seven Bridges Genomics Inc. Methods and systems for aligning sequences in the presence of repeating elements
WO2015058095A1 (en) 2013-10-18 2015-04-23 Seven Bridges Genomics Inc. Methods and systems for quantifying sequence alignment
US9063914B2 (en) 2013-10-21 2015-06-23 Seven Bridges Genomics Inc. Systems and methods for transcriptome analysis
CA2935941C (en) 2014-01-10 2022-05-17 Seven Bridges Genomics Inc. Systems and methods for use of known alleles in read mapping
US9817944B2 (en) 2014-02-11 2017-11-14 Seven Bridges Genomics Inc. Systems and methods for analyzing sequence data
CA2964349C (en) 2014-10-14 2023-03-21 Seven Bridges Genomics Inc. Systems and methods for smart tools in sequence pipelines
WO2016141294A1 (en) 2015-03-05 2016-09-09 Seven Bridges Genomics Inc. Systems and methods for genomic pattern analysis
US10275567B2 (en) 2015-05-22 2019-04-30 Seven Bridges Genomics Inc. Systems and methods for haplotyping
CA2930597A1 (en) 2015-05-22 2016-11-22 The University Of British Columbia Methods for the graphical representation of genomic sequence data
US10793895B2 (en) 2015-08-24 2020-10-06 Seven Bridges Genomics Inc. Systems and methods for epigenetic analysis
US10724110B2 (en) 2015-09-01 2020-07-28 Seven Bridges Genomics Inc. Systems and methods for analyzing viral nucleic acids
US10584380B2 (en) 2015-09-01 2020-03-10 Seven Bridges Genomics Inc. Systems and methods for mitochondrial analysis
US11347704B2 (en) 2015-10-16 2022-05-31 Seven Bridges Genomics Inc. Biological graph or sequence serialization
US10853130B1 (en) * 2015-12-02 2020-12-01 Color Genomics, Inc. Load balancing and conflict processing in workflow with task dependencies
US20170199960A1 (en) 2016-01-07 2017-07-13 Seven Bridges Genomics Inc. Systems and methods for adaptive local alignment for graph genomes
US10364468B2 (en) 2016-01-13 2019-07-30 Seven Bridges Genomics Inc. Systems and methods for analyzing circulating tumor DNA
US10460829B2 (en) 2016-01-26 2019-10-29 Seven Bridges Genomics Inc. Systems and methods for encoding genetic variation for a population
US10262102B2 (en) 2016-02-24 2019-04-16 Seven Bridges Genomics Inc. Systems and methods for genotyping with graph reference
US10790044B2 (en) 2016-05-19 2020-09-29 Seven Bridges Genomics Inc. Systems and methods for sequence encoding, storage, and compression
US10600499B2 (en) 2016-07-13 2020-03-24 Seven Bridges Genomics Inc. Systems and methods for reconciling variants in sequence data relative to reference sequence data
US11289177B2 (en) 2016-08-08 2022-03-29 Seven Bridges Genomics, Inc. Computer method and system of identifying genomic mutations using graph-based local assembly
US11250931B2 (en) 2016-09-01 2022-02-15 Seven Bridges Genomics Inc. Systems and methods for detecting recombination
EA201990933A1 (en) * 2016-10-11 2019-11-29 EFFECTIVE DATA STRUCTURES FOR THE SUBMISSION OF BIOINFORMATICS INFORMATION
US10319465B2 (en) 2016-11-16 2019-06-11 Seven Bridges Genomics Inc. Systems and methods for aligning sequences to graph references
CN106682393B (en) * 2016-11-29 2019-05-17 北京荣之联科技股份有限公司 Genome sequence alignment method and device
US10629292B2 (en) * 2016-12-19 2020-04-21 Seven Bridges Genomics, Inc. Generation and use of simulated genomic data
CN106874339B (en) * 2016-12-20 2020-12-08 北京华宇信息技术有限公司 Display method of directed cyclic graph and application thereof
US11347844B2 (en) 2017-03-01 2022-05-31 Seven Bridges Genomics, Inc. Data security in bioinformatic sequence analysis
US10726110B2 (en) 2017-03-01 2020-07-28 Seven Bridges Genomics, Inc. Watermarking for data security in bioinformatic sequence analysis
CN107992294A (en) * 2017-12-20 2018-05-04 成都优易数据有限公司 A kind of general information representation and the super data structure of information transmission
US12046325B2 (en) 2018-02-14 2024-07-23 Seven Bridges Genomics Inc. System and method for sequence identification in reassembly variant calling
CA3100607A1 (en) * 2018-05-23 2019-11-28 Envisagenics, Inc. Systems and methods for analysis of alternative splicing
US10671632B1 (en) 2019-09-03 2020-06-02 Cb Therapeutics, Inc. Automated pipeline
US20210139977A1 (en) * 2019-11-07 2021-05-13 Hong Kong Baptist University Method for identifying RNA isoforms in transcriptome using Nanopore RNA reads
CN111445956B (en) * 2020-04-23 2021-06-22 北京吉因加医学检验实验室有限公司 Efficient genome data utilization method and device for second-generation sequencing platform
CN113012755B (en) * 2021-04-12 2023-10-27 聊城大学 Genome ATCG search method
US20240428882A1 (en) * 2021-08-20 2024-12-26 Diagenode Sa Computer-implemented methods and systems for transcriptomics
CN114283880B (en) * 2022-01-21 2025-04-11 山东大学 A transcript assembly method based on reference genome

Family Cites Families (142)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5242794A (en) 1984-12-13 1993-09-07 Applied Biosystems, Inc. Detection of specific sequences in nucleic acids
US4683195A (en) 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
US4683202A (en) 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
US5583024A (en) 1985-12-02 1996-12-10 The Regents Of The University Of California Recombinant expression of Coleoptera luciferase
US4988617A (en) 1988-03-25 1991-01-29 California Institute Of Technology Method of detecting a nucleotide change in nucleic acids
US5234809A (en) 1989-03-23 1993-08-10 Akzo N.V. Process for isolating nucleic acid
US5494810A (en) 1990-05-03 1996-02-27 Cornell Research Foundation, Inc. Thermostable ligase-mediated DNA amplifications system for the detection of genetic disease
US5511158A (en) 1994-08-04 1996-04-23 Thinking Machines Corporation System and method for creating and evolving directed graphs
US5750341A (en) 1995-04-17 1998-05-12 Lynx Therapeutics, Inc. DNA sequencing by parallel oligonucleotide extensions
US5701256A (en) 1995-05-31 1997-12-23 Cold Spring Harbor Laboratory Method and apparatus for biological sequence comparison
GB9620209D0 (en) 1996-09-27 1996-11-13 Cemu Bioteknik Ab Method of sequencing DNA
US6054278A (en) 1997-05-05 2000-04-25 The Perkin-Elmer Corporation Ribosomal RNA gene polymorphism based microorganism identification
AU9317198A (en) 1997-09-17 1999-04-05 Gentra Systems, Inc. Apparatuses and methods for isolating nucleic acid
US6054276A (en) 1998-02-23 2000-04-25 Macevicz; Stephen C. DNA restriction site mapping
US6223128B1 (en) 1998-06-29 2001-04-24 Dnstar, Inc. DNA sequence assembly system
US6787308B2 (en) 1998-07-30 2004-09-07 Solexa Ltd. Arrayed biomolecules and their use in sequencing
GB9901475D0 (en) 1999-01-22 1999-03-17 Pyrosequencing Ab A method of DNA sequencing
US6818395B1 (en) 1999-06-28 2004-11-16 California Institute Of Technology Methods and apparatus for analyzing polynucleotide sequences
WO2001023610A2 (en) 1999-09-29 2001-04-05 Solexa Ltd. Polynucleotide sequencing
US6582938B1 (en) 2001-05-11 2003-06-24 Affymetrix, Inc. Amplification of nucleic acids
US6448717B1 (en) 2000-07-17 2002-09-10 Micron Technology, Inc. Method and apparatuses for providing uniform electron beams from field emission displays
JP5246984B2 (en) 2000-07-18 2013-07-24 アングーク ファーマシューティカル カンパニー，リミティド A method for distinguishing between biological states based on patterns hidden from biological data
NO20004869D0 (en) 2000-09-28 2000-09-28 Torbjoern Rognes Method for fast optimal local sequence alignment using parallel processing
EP1368497A4 (en) 2001-03-12 2007-08-15 California Inst Of Techn METHOD AND DEVICE FOR ANALYZING POLYNUCLEOTIDE SEQUENCES BY ASYNCHRONOUS BASE EXTENSION
US6890763B2 (en) 2001-04-30 2005-05-10 Syn X Pharma, Inc. Biopolymer marker indicative of disease state having a molecular weight of 1350 daltons
US7809509B2 (en) 2001-05-08 2010-10-05 Ip Genesis, Inc. Comparative mapping and assembly of nucleic acid sequences
US7577554B2 (en) 2001-07-03 2009-08-18 I2 Technologies Us, Inc. Workflow modeling using an acyclic directed graph data structure
US20040023209A1 (en) 2001-11-28 2004-02-05 Jon Jonasson Method for identifying microorganisms based on sequencing gene fragments
US6989100B2 (en) 2002-05-09 2006-01-24 Ppd Biomarker Discovery Sciences, Llc Methods for time-alignment of liquid chromatography-mass spectrometry data
US7321623B2 (en) 2002-10-01 2008-01-22 Avocent Corporation Video compression system
US7225324B2 (en) 2002-10-31 2007-05-29 Src Computers, Inc. Multi-adaptive processing systems and techniques for enhancing parallelism and performance of computational functions
AU2003303502A1 (en) * 2002-12-27 2004-07-29 Rosetta Inpharmatics Llc Computer systems and methods for associating genes with traits using cross species data
US7885840B2 (en) 2003-01-07 2011-02-08 Sap Aktiengesellschaft System and method of flexible workflow management
US7575865B2 (en) 2003-01-29 2009-08-18 454 Life Sciences Corporation Methods of amplifying and sequencing nucleic acids
US7953891B2 (en) 2003-03-18 2011-05-31 Microsoft Corporation Systems and methods for scheduling data flow execution based on an arbitrary graph describing the desired data flow
JP2005092719A (en) 2003-09-19 2005-04-07 Nec Corp Haplotype estimation method, estimation system, and program
ATE510024T1 (en) 2003-10-31 2011-06-15 Advanced Genetic Analysis Corp Ab METHOD FOR PRODUCING A PAIRED TAG FROM A NUCLEIC ACID SEQUENCE AND METHOD FOR USE THEREOF
US7169560B2 (en) 2003-11-12 2007-01-30 Helicos Biosciences Corporation Short cycle methods for sequencing polynucleotides
US20060195266A1 (en) 2005-02-25 2006-08-31 Yeatman Timothy J Methods for predicting cancer outcome and gene signatures for use therein
US8185367B2 (en) * 2004-04-30 2012-05-22 Merck Sharp & Dohme Corp. Systems and methods for reconstructing gene networks in segregating populations
US7642511B2 (en) 2004-09-30 2010-01-05 Ut-Battelle, Llc Ultra high mass range mass spectrometer systems
WO2006052242A1 (en) 2004-11-08 2006-05-18 Seirad, Inc. Methods and systems for compressing and comparing genomic data
US7483585B2 (en) 2004-12-01 2009-01-27 Ati Technologies Ulc Image compression using variable bit size run length encoding
US20080003571A1 (en) 2005-02-01 2008-01-03 Mckernan Kevin Reagents, methods, and libraries for bead-based sequencing
WO2007145612A1 (en) 2005-06-06 2007-12-21 454 Life Sciences Corporation Paired end sequencing
US7329860B2 (en) 2005-11-23 2008-02-12 Illumina, Inc. Confocal imaging methods and apparatus
KR100722504B1 (en) 2006-01-18 2007-05-29 학교법인 포항공과대학교 Nonlinear Process Plan Generation Method and Internet-based STEP-NC System
US7580918B2 (en) 2006-03-03 2009-08-25 Adobe Systems Incorporated System and method of efficiently representing and searching directed acyclic graph structures in databases
GB2436564A (en) * 2006-03-31 2007-10-03 Plant Bioscience Ltd Prediction of heterosis and other traits by transcriptome analysis
US7282337B1 (en) 2006-04-14 2007-10-16 Helicos Biosciences Corporation Methods for increasing accuracy of nucleic acid sequencing
US7702468B2 (en) 2006-05-03 2010-04-20 Population Diagnostics, Inc. Evaluating genetic disorders
US7754429B2 (en) 2006-10-06 2010-07-13 Illumina Cambridge Limited Method for pair-wise sequencing a plurity of target polynucleotides
EP2463390A1 (en) 2006-10-20 2012-06-13 Innogenetics N.V. Methodology for analysis of sequence variations within the HCV NS5B genomic region
US8262900B2 (en) 2006-12-14 2012-09-11 Life Technologies Corporation Methods and apparatus for measuring analytes using large scale FET arrays
EP2677308B1 (en) 2006-12-14 2017-04-26 Life Technologies Corporation Method for fabricating large scale FET arrays
US8349167B2 (en) 2006-12-14 2013-01-08 Life Technologies Corporation Methods and apparatus for detecting molecular interactions using FET arrays
EP2126765B1 (en) 2007-01-26 2011-08-24 Illumina Inc. Nucleic acid sequencing system and method
US8165821B2 (en) 2007-02-05 2012-04-24 Applied Biosystems, Llc System and methods for indel identification using short read sequencing
US8146099B2 (en) 2007-09-27 2012-03-27 Microsoft Corporation Service-oriented pipeline based architecture
US20090119313A1 (en) 2007-11-02 2009-05-07 Ioactive Inc. Determining structure of binary data using alignment algorithms
US8478544B2 (en) 2007-11-21 2013-07-02 Cosmosid Inc. Direct identification and measurement of relative populations of microorganisms with direct DNA sequencing and probabilistic methods
US20090233809A1 (en) 2008-03-04 2009-09-17 Affymetrix, Inc. Resequencing methods for identification of sequence variants
US8271206B2 (en) 2008-04-21 2012-09-18 Softgenetics Llc DNA sequence assembly methods of short reads
US20100010992A1 (en) 2008-07-10 2010-01-14 Morris Robert P Methods And Systems For Resolving A Location Information To A Network Identifier
KR100992169B1 (en) 2008-07-25 2010-11-04 한국생명공학연구원 Information Analysis Process Recommendation Design System and Method
US20100041048A1 (en) 2008-07-31 2010-02-18 The Johns Hopkins University Circulating Mutant DNA to Assess Tumor Dynamics
US20100035252A1 (en) 2008-08-08 2010-02-11 Ion Torrent Systems Incorporated Methods for sequencing individual nucleic acids under tension
WO2010033822A2 (en) * 2008-09-19 2010-03-25 Immune Disease Institute, Inc Therapeutic and diagnostic strategies
US20100301398A1 (en) 2009-05-29 2010-12-02 Ion Torrent Systems Incorporated Methods and apparatus for measuring analytes
US20100137143A1 (en) 2008-10-22 2010-06-03 Ion Torrent Systems Incorporated Methods and apparatus for measuring analytes
US8546128B2 (en) 2008-10-22 2013-10-01 Life Technologies Corporation Fluidics system for sequential delivery of reagents
US8691510B2 (en) 2008-11-07 2014-04-08 Sequenta, Inc. Sequence analysis of complex amplicons
WO2010059235A2 (en) 2008-11-20 2010-05-27 Pacific Biosciences Of California, Inc. Algorithms for sequence determination
WO2010075570A2 (en) 2008-12-24 2010-07-01 New York University Methods, computer-accessible medium, and systems for score-driven whole-genome shotgun sequence assemble
JP5782384B2 (en) 2009-02-03 2015-09-24 ネットバイオ・インコーポレーテッドＮｅｔＢｉｏ， Ｉｎｃ． Self-contained apparatus and purification method for isolating nucleic acids from untreated samples
US8352195B2 (en) 2009-03-20 2013-01-08 Siemens Corporation Methods and systems for identifying PCR primers specific to one or more target genomes
EP2511843B1 (en) 2009-04-29 2016-12-21 Complete Genomics, Inc. Method and system for calling variations in a sample polynucleotide sequence with respect to a reference polynucleotide sequence
US8574835B2 (en) 2009-05-29 2013-11-05 Life Technologies Corporation Scaffolded nucleic acid polymer particles and methods of making and using
US8673627B2 (en) 2009-05-29 2014-03-18 Life Technologies Corporation Apparatus and methods for performing electrochemical reactions
US9524369B2 (en) * 2009-06-15 2016-12-20 Complete Genomics, Inc. Processing and analysis of complex nucleic acid sequence data
WO2011050341A1 (en) 2009-10-22 2011-04-28 National Center For Genome Resources Methods and systems for medical sequencing analysis
JP2011091775A (en) 2009-10-26 2011-05-06 Toshiba Corp Solid-state image pickup device
WO2011087501A1 (en) 2010-01-14 2011-07-21 Fluor Technologies Corporation 3d plant modeling systems and methods
US20130210645A1 (en) 2010-02-18 2013-08-15 The Johns Hopkins University Personalized tumor biomarkers
US9165109B2 (en) 2010-02-24 2015-10-20 Pacific Biosciences Of California, Inc. Sequence assembly and consensus sequence determination
US20110257889A1 (en) 2010-02-24 2011-10-20 Pacific Biosciences Of California, Inc. Sequence assembly and consensus sequence determination
WO2011139797A2 (en) 2010-04-27 2011-11-10 Spiral Genetics Inc. Method and system for analysis and error correction of biological sequences and inference of relationship for multiple samples
US20120030566A1 (en) 2010-07-28 2012-02-02 Victor B Michael System with touch-based selection of data items
WO2012034030A1 (en) 2010-09-09 2012-03-15 Omicia, Inc. Variant annotation, analysis and selection tool
US9309556B2 (en) 2010-09-24 2016-04-12 The Board Of Trustees Of The Leland Stanford Junior University Direct capture, amplification and sequencing of target DNA using immobilized primers
US20130331277A1 (en) 2011-01-14 2013-12-12 Keygene N.V. Paired end random sequence based genotyping
KR101285935B1 (en) 2011-01-19 2013-07-12 주식회사 엘지실트론 Resistance Heating Grower of Sapphire Single Crystal Ingot, Manufacturing Method of Sapphire Single Crystal Ingot using Resistance Heating, Sapphire Single Crystal Ingot and Sapphire Wafer
EP2666115A1 (en) 2011-01-19 2013-11-27 Koninklijke Philips N.V. Method for processing genomic data
US20120239706A1 (en) 2011-03-18 2012-09-20 Los Alamos National Security, Llc Computer-facilitated parallel information alignment and analysis
AU2012242525B2 (en) 2011-04-14 2015-09-17 Complete Genomics, Inc. Processing and analysis of complex nucleic acid sequence data
TW201243117A (en) * 2011-04-28 2012-11-01 Hsueh-Ting Chu Method and system of assembling DNA reads with paired-end sequencing
US9506167B2 (en) 2011-07-29 2016-11-29 Ginkgo Bioworks, Inc. Methods and systems for cell state quantification
KR101282798B1 (en) 2011-09-08 2013-07-04 한국과학기술정보연구원 System and method for processing bio information analysis pipeline
WO2013035904A1 (en) 2011-09-08 2013-03-14 한국과학기술정보연구원 System and method for processing bio information analysis pipeline
WO2013043909A1 (en) 2011-09-20 2013-03-28 Life Technologies Corporation Systems and methods for identifying sequence variation
US8954475B2 (en) 2011-11-10 2015-02-10 Microsoft Technology Licensing, Llc Deep cloning of objects using binary format
CN102409099A (en) * 2011-11-29 2012-04-11 浙江大学 Method for analyzing difference of gene expression of porcine mammary gland tissue by sequencing technology
EP2608096B1 (en) 2011-12-24 2020-08-05 Tata Consultancy Services Ltd. Compression of genomic data file
WO2013097257A1 (en) 2011-12-31 2013-07-04 深圳华大基因科技有限公司 Method and system for testing fusion gene
EP3434789A1 (en) 2012-01-13 2019-01-30 Data2Bio Genotyping by next-generation sequencing
US9047133B2 (en) 2012-03-02 2015-06-02 Vmware, Inc. Single, logical, multi-tier application blueprint used for deployment and management of multiple physical applications in a cloud environment
US9552458B2 (en) 2012-03-16 2017-01-24 The Research Institute At Nationwide Children's Hospital Comprehensive analysis pipeline for discovery of human genetic variation
US8209130B1 (en) 2012-04-04 2012-06-26 Good Start Genetics, Inc. Sequence assembly
US20130345066A1 (en) 2012-05-09 2013-12-26 Life Technologies Corporation Systems and methods for identifying sequence variation
US20130324417A1 (en) 2012-06-04 2013-12-05 Good Start Genetics, Inc. Determining the clinical significance of variant sequences
US9104656B2 (en) 2012-07-03 2015-08-11 International Business Machines Corporation Using lexical analysis and parsing in genome research
US10777301B2 (en) 2012-07-13 2020-09-15 Pacific Biosciences For California, Inc. Hierarchical genome assembly method using single long insert library
US20150293994A1 (en) 2012-11-06 2015-10-15 Hewlett-Packard Development Company, L.P. Enhanced graph traversal
WO2014074246A1 (en) 2012-11-07 2014-05-15 Good Start Genetics, Inc. Validation of genetic tests
EP2946345B1 (en) 2013-01-17 2024-04-03 Personalis, Inc. Methods and systems for genetic analysis
US10346551B2 (en) 2013-01-24 2019-07-09 New York University Systems, methods and computer-accessible mediums for utilizing pattern matching in stringomes
US10032195B2 (en) 2013-03-13 2018-07-24 Airline Tariff Publishing Company System, method and computer program product for providing a fare analytic engine
US9087007B2 (en) 2013-03-14 2015-07-21 International Business Machines Corporation Generating fault tolerant connectivity API
EP2973044A2 (en) 2013-03-15 2016-01-20 James Webber Graph database devices and methods for partitioning graphs
US9189224B2 (en) 2013-07-11 2015-11-17 Oracle International Corporation Forming an upgrade recommendation in a cloud computing environment
US9898575B2 (en) 2013-08-21 2018-02-20 Seven Bridges Genomics Inc. Methods and systems for aligning sequences
US9116866B2 (en) 2013-08-21 2015-08-25 Seven Bridges Genomics Inc. Methods and systems for detecting sequence variants
US20150066383A1 (en) 2013-09-03 2015-03-05 Seven Bridges Genomics Inc. Collapsible modular genomic pipeline
AU2014324438B2 (en) 2013-09-30 2019-12-05 Seven Bridges Genomics Inc. Methods and system for detecting sequence variants
AU2014335877B2 (en) 2013-10-15 2020-09-17 Regeneron Pharmaceuticals, Inc. High resolution allele identification
WO2015058095A1 (en) 2013-10-18 2015-04-23 Seven Bridges Genomics Inc. Methods and systems for quantifying sequence alignment
CN105793689B (en) 2013-10-18 2020-04-17 七桥基因公司 Methods and systems for genotyping genetic samples
WO2015058097A1 (en) 2013-10-18 2015-04-23 Seven Bridges Genomics Inc. Methods and systems for identifying disease-induced mutations
WO2015058120A1 (en) 2013-10-18 2015-04-23 Seven Bridges Genomics Inc. Methods and systems for aligning sequences in the presence of repeating elements
US9063914B2 (en) 2013-10-21 2015-06-23 Seven Bridges Genomics Inc. Systems and methods for transcriptome analysis
CA2935941C (en) 2014-01-10 2022-05-17 Seven Bridges Genomics Inc. Systems and methods for use of known alleles in read mapping
US9817944B2 (en) 2014-02-11 2017-11-14 Seven Bridges Genomics Inc. Systems and methods for analyzing sequence data
WO2016141294A1 (en) 2015-03-05 2016-09-09 Seven Bridges Genomics Inc. Systems and methods for genomic pattern analysis
US20160364523A1 (en) 2015-06-11 2016-12-15 Seven Bridges Genomics Inc. Systems and methods for identifying microorganisms
US9617944B2 (en) 2015-07-28 2017-04-11 GM Global Technology Operations LLC Over-fueling control based on oxygen sensor feedback
US10793895B2 (en) 2015-08-24 2020-10-06 Seven Bridges Genomics Inc. Systems and methods for epigenetic analysis
US10584380B2 (en) 2015-09-01 2020-03-10 Seven Bridges Genomics Inc. Systems and methods for mitochondrial analysis
US10724110B2 (en) 2015-09-01 2020-07-28 Seven Bridges Genomics Inc. Systems and methods for analyzing viral nucleic acids
US20170199960A1 (en) 2016-01-07 2017-07-13 Seven Bridges Genomics Inc. Systems and methods for adaptive local alignment for graph genomes
US10364468B2 (en) 2016-01-13 2019-07-30 Seven Bridges Genomics Inc. Systems and methods for analyzing circulating tumor DNA
US20170199959A1 (en) 2016-01-13 2017-07-13 Seven Bridges Genomics Inc. Genetic analysis systems and methods
US10262102B2 (en) 2016-02-24 2019-04-16 Seven Bridges Genomics Inc. Systems and methods for genotyping with graph reference

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