SG10202007176TA - Anti-cd47 antibodies and uses thereof - Google Patents
Anti-cd47 antibodies and uses thereofInfo
- Publication number
- SG10202007176TA SG10202007176TA SG10202007176TA SG10202007176TA SG10202007176TA SG 10202007176T A SG10202007176T A SG 10202007176TA SG 10202007176T A SG10202007176T A SG 10202007176TA SG 10202007176T A SG10202007176T A SG 10202007176TA SG 10202007176T A SG10202007176T A SG 10202007176TA
- Authority
- SG
- Singapore
- Prior art keywords
- antibodies
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/39541—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against normal tissues, cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/10—Immunoglobulins specific features characterized by their source of isolation or production
- C07K2317/14—Specific host cells or culture conditions, e.g. components, pH or temperature
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
- C07K2317/732—Antibody-dependent cellular cytotoxicity [ADCC]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
- C07K2317/734—Complement-dependent cytotoxicity [CDC]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/94—Stability, e.g. half-life, pH, temperature or enzyme-resistance
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- Biophysics (AREA)
- Epidemiology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Mycology (AREA)
- Hematology (AREA)
- Oncology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462098291P | 2014-12-30 | 2014-12-30 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG10202007176TA true SG10202007176TA (en) | 2020-08-28 |
Family
ID=56284963
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201705310TA SG11201705310TA (en) | 2014-12-30 | 2015-12-28 | Anti-cd47 antibodies and uses thereof |
| SG10202007176TA SG10202007176TA (en) | 2014-12-30 | 2015-12-28 | Anti-cd47 antibodies and uses thereof |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201705310TA SG11201705310TA (en) | 2014-12-30 | 2015-12-28 | Anti-cd47 antibodies and uses thereof |
Country Status (17)
| Country | Link |
|---|---|
| US (2) | US10870699B2 (en) |
| EP (1) | EP3240569A4 (en) |
| JP (2) | JP6850255B2 (en) |
| KR (1) | KR102489471B1 (en) |
| CN (1) | CN107530421B (en) |
| AU (1) | AU2015374301B2 (en) |
| BR (1) | BR112017014258A2 (en) |
| CA (1) | CA2972604C (en) |
| CL (1) | CL2017001736A1 (en) |
| CO (1) | CO2017007673A2 (en) |
| EA (1) | EA037654B1 (en) |
| EC (1) | ECSP17041865A (en) |
| HK (1) | HK1245154A1 (en) |
| MX (1) | MX391051B (en) |
| SG (2) | SG11201705310TA (en) |
| WO (1) | WO2016109415A1 (en) |
| ZA (1) | ZA201704467B (en) |
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| MY149129A (en) | 2007-03-20 | 2013-07-15 | Lilly Co Eli | Anti-sclerostin antibodies |
| EP2111869A1 (en) | 2008-04-23 | 2009-10-28 | Stichting Sanquin Bloedvoorziening | Compositions and methods to enhance the immune system |
| WO2011004847A1 (en) | 2009-07-07 | 2011-01-13 | 一般財団法人化学及血清療法研究所 | NOVEL HUMANIZED ANTI-HUMAN α9-INTEGRIN ANTIBODY |
| US8758750B2 (en) | 2009-09-15 | 2014-06-24 | The Board Of Trustees Of The Leland Stanford Junior University | Synergistic anti-CD47 therapy for hematologic cancers |
| US20140193408A1 (en) * | 2011-06-16 | 2014-07-10 | Novartis Ag | Soluble proteins for use as therapeutics |
| EP3766511A1 (en) * | 2012-01-17 | 2021-01-20 | The Board of Trustees of the Leland Stanford Junior University | High affinity sirp-alpha reagents |
| US20140140989A1 (en) | 2012-02-06 | 2014-05-22 | Inhibrx Llc | Non-Platelet Depleting and Non-Red Blood Cell Depleting CD47 Antibodies and Methods of Use Thereof |
| KR102338833B1 (en) * | 2012-02-06 | 2021-12-13 | 인히브릭스, 인크. | Cd47 antibodies and methods of use thereof |
| WO2014123580A1 (en) * | 2013-02-06 | 2014-08-14 | Inhibrx Llc | Non-platelet depleting and non-red blood cell depleting cd47 antibodies and methods of use thereof |
| SG10202108497TA (en) * | 2013-04-19 | 2021-09-29 | Sutro Biopharma Inc | Expression of biologically active proteins in a bacterial cell-free synthesis system using cell extracts with elevated levels of exogenous chaperones |
| EA037654B1 (en) | 2014-12-30 | 2021-04-27 | Селджин Корпорейшн | Anti-cd47 antibodies and uses thereof |
| EP3349787A4 (en) | 2015-09-18 | 2019-03-27 | Arch Oncology, Inc. | THERAPEUTIC CD47 ANTIBODIES |
| AU2016326423A1 (en) | 2015-09-21 | 2018-04-26 | Erasmus University Medical Center | Anti-CD47 antibodies and methods of use |
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2015
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- 2015-12-28 WO PCT/US2015/067642 patent/WO2016109415A1/en not_active Ceased
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- 2015-12-28 EP EP15876093.4A patent/EP3240569A4/en not_active Withdrawn
- 2015-12-28 HK HK18104961.7A patent/HK1245154A1/en unknown
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2017
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2020
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| AU2015374301A1 (en) | 2017-07-20 |
| US20210054070A1 (en) | 2021-02-25 |
| CA2972604A1 (en) | 2016-07-07 |
| CN107530421A (en) | 2018-01-02 |
| CL2017001736A1 (en) | 2018-03-16 |
| EP3240569A4 (en) | 2018-05-30 |
| WO2016109415A1 (en) | 2016-07-07 |
| AU2015374301B2 (en) | 2021-02-11 |
| EP3240569A1 (en) | 2017-11-08 |
| JP6850255B2 (en) | 2021-03-31 |
| JP2018506964A (en) | 2018-03-15 |
| MX391051B (en) | 2025-03-21 |
| KR20170100652A (en) | 2017-09-04 |
| US11787860B2 (en) | 2023-10-17 |
| EA201791485A1 (en) | 2018-02-28 |
| CA2972604C (en) | 2023-07-04 |
| CN107530421B (en) | 2021-07-20 |
| JP2021048858A (en) | 2021-04-01 |
| CO2017007673A2 (en) | 2018-01-05 |
| US10870699B2 (en) | 2020-12-22 |
| ECSP17041865A (en) | 2017-08-31 |
| HK1245154A1 (en) | 2018-08-24 |
| SG11201705310TA (en) | 2017-07-28 |
| ZA201704467B (en) | 2019-09-25 |
| BR112017014258A2 (en) | 2018-03-06 |
| EA037654B1 (en) | 2021-04-27 |
| KR102489471B1 (en) | 2023-01-18 |
| MX2017008819A (en) | 2018-03-14 |
| US20170369572A1 (en) | 2017-12-28 |
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