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SE9901059L - Method for making particles - Google Patents

Method for making particles

Info

Publication number
SE9901059L
SE9901059L SE9901059A SE9901059A SE9901059L SE 9901059 L SE9901059 L SE 9901059L SE 9901059 A SE9901059 A SE 9901059A SE 9901059 A SE9901059 A SE 9901059A SE 9901059 L SE9901059 L SE 9901059L
Authority
SE
Sweden
Prior art keywords
scf
liquid
substance
substance liquid
particles
Prior art date
Application number
SE9901059A
Other languages
Unknown language ( )
Swedish (sv)
Other versions
SE9901059D0 (en
Inventor
Johan Carlfors
Raouf Ghaderi
Original Assignee
Johan Carlfors
Raouf Ghaderi
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Johan Carlfors, Raouf Ghaderi filed Critical Johan Carlfors
Priority to SE9901059A priority Critical patent/SE9901059L/en
Publication of SE9901059D0 publication Critical patent/SE9901059D0/en
Priority to AU41578/00A priority patent/AU4157800A/en
Priority to PCT/SE2000/000566 priority patent/WO2000056439A1/en
Publication of SE9901059L publication Critical patent/SE9901059L/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Extraction Or Liquid Replacement (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Medicinal Preparation (AREA)

Abstract

The invention relates to a method for the preparation of particles comprising the following steps: the dispersion, with a first supercritical fluid (SCF-D), of a substance liquid at least comprising a mixture of a substance, of which particles are to be prepared, and a liquid carrier medium; and the subsequent extraction, with another supercritical fluid (SCF-E), after the dispersion of the substance liquid, of the liquid carrier medium. An apparatus according to the invention comprises a particle formation reactor (2), the pressure and temperature of which are controllable; means (18, 21) for the delivery of a substance liquid; feeding means (22, 17; 12, 6) for two different supercritical fluids (SCF-D, SCF-E); a nozzle (17) for dispersing the substance liquid; and for feeding of the dispersed substance liquid to the particle formation reactor (2).
SE9901059A 1999-03-22 1999-03-22 Method for making particles SE9901059L (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
SE9901059A SE9901059L (en) 1999-03-22 1999-03-22 Method for making particles
AU41578/00A AU4157800A (en) 1999-03-22 2000-03-22 Method for the preparation of particles
PCT/SE2000/000566 WO2000056439A1 (en) 1999-03-22 2000-03-22 Method for the preparation of particles

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE9901059A SE9901059L (en) 1999-03-22 1999-03-22 Method for making particles

Publications (2)

Publication Number Publication Date
SE9901059D0 SE9901059D0 (en) 1999-03-22
SE9901059L true SE9901059L (en) 2000-09-23

Family

ID=20414970

Family Applications (1)

Application Number Title Priority Date Filing Date
SE9901059A SE9901059L (en) 1999-03-22 1999-03-22 Method for making particles

Country Status (3)

Country Link
AU (1) AU4157800A (en)
SE (1) SE9901059L (en)
WO (1) WO2000056439A1 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2002236021B2 (en) * 2001-02-26 2006-11-16 Dompe' Pha.R.Ma S.P.A. Apparatus and method for micron and submicron particle formation
TW586963B (en) * 2001-07-20 2004-05-11 Nektar Therapeutics Uk Ltd Method and apparatus for preparing target substance in particulate form and fluid inlet assembly for said apparatus
US20070079629A1 (en) * 2003-10-30 2007-04-12 Laboratories Serono S.A. Process and apparatus for cooling and atomizing liquid or pasty-like substances

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4568495A (en) * 1983-05-16 1986-02-04 Union Camp Corporation Fractionation of polymerized fatty acids
JPH078202A (en) * 1993-06-29 1995-01-13 Lion Corp Method for producing spice extract
GB9413202D0 (en) * 1994-06-30 1994-08-24 Univ Bradford Method and apparatus for the formation of particles
GB9703673D0 (en) * 1997-02-21 1997-04-09 Bradford Particle Design Ltd Method and apparatus for the formation of particles

Also Published As

Publication number Publication date
WO2000056439A1 (en) 2000-09-28
AU4157800A (en) 2000-10-09
SE9901059D0 (en) 1999-03-22

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