SE8503869L - SET TO PREPARE 6-SUBSTITUTED FURO (3,4-C) PYRIDINE DERIVATIVES - Google Patents
SET TO PREPARE 6-SUBSTITUTED FURO (3,4-C) PYRIDINE DERIVATIVESInfo
- Publication number
- SE8503869L SE8503869L SE8503869A SE8503869A SE8503869L SE 8503869 L SE8503869 L SE 8503869L SE 8503869 A SE8503869 A SE 8503869A SE 8503869 A SE8503869 A SE 8503869A SE 8503869 L SE8503869 L SE 8503869L
- Authority
- SE
- Sweden
- Prior art keywords
- c5alkoxy
- c5alkyl
- prepare
- pyridine derivatives
- amino
- Prior art date
Links
- -1 6-SUBSTITUTED FURO (3,4-C) PYRIDINE Chemical class 0.000 title abstract 2
- WYURNTSHIVDZCO-UHFFFAOYSA-N Tetrahydrofuran Chemical compound C1CCOC1 WYURNTSHIVDZCO-UHFFFAOYSA-N 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 208000004880 Polyuria Diseases 0.000 abstract 1
- AVZNLXBMQVKETP-UHFFFAOYSA-M [Br-].CN(C)CC([Mg+])=C Chemical compound [Br-].CN(C)CC([Mg+])=C AVZNLXBMQVKETP-UHFFFAOYSA-M 0.000 abstract 1
- 239000000739 antihistaminic agent Substances 0.000 abstract 1
- 229940125715 antihistaminic agent Drugs 0.000 abstract 1
- 230000036772 blood pressure Effects 0.000 abstract 1
- 230000035619 diuresis Effects 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- 210000003734 kidney Anatomy 0.000 abstract 1
- 239000012454 non-polar solvent Substances 0.000 abstract 1
- 125000003884 phenylalkyl group Chemical group 0.000 abstract 1
- 125000006413 ring segment Chemical group 0.000 abstract 1
- YLQBMQCUIZJEEH-UHFFFAOYSA-N tetrahydrofuran Natural products C=1C=COC=1 YLQBMQCUIZJEEH-UHFFFAOYSA-N 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Psychiatry (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyridine Compounds (AREA)
Abstract
<IMAGE> The compounds I (A1, A2 independently = H, C1-C5hydrocarbon, heterocycle up to 6 ring atoms, carbomonocycle, phenylalkyl, phenylalkenyl; each (except H) unsubstituted or substituted by one or more of F, Cl, CF3, C1-C5alkyl, C1-C5alkoxy, C1-C5alkylthio, di(C1-C5alkyl)-amino, di(C1-C5alkyl)-amino- (C1-C5alkoxy), alpha - or beta -(C1-C5alkoxy)-N-pyrrolidinyl), which are known compounds of interest for their therapeutical activity, principally in the fields of diuresis, lowering of blood pressure, kidney protection and also as antihistaminic agents, are prepared by reacting the corresponding 6-formyl derivatives with 1- dimethylaminomethyl-vinylmagnesium bromide at the boil in a non-polar solvent such as tetrahydrofuran.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB848422029A GB8422029D0 (en) | 1984-08-31 | 1984-08-31 | 6-substituted-furo-(3 4-c)-pyridine derivatives |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| SE8503869D0 SE8503869D0 (en) | 1985-08-19 |
| SE8503869L true SE8503869L (en) | 1986-03-01 |
| SE462218B SE462218B (en) | 1990-05-21 |
Family
ID=10566078
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE8503869A SE462218B (en) | 1984-08-31 | 1985-08-19 | PROCEDURES FOR PREPARATION OF 6-SUBSTITUTED FURO- (3,4, -C) -PYRIDINE DERIVATIVES |
Country Status (22)
| Country | Link |
|---|---|
| JP (1) | JPS6160688A (en) |
| AR (1) | AR241455A1 (en) |
| AT (1) | AT396590B (en) |
| BE (1) | BE903122A (en) |
| CA (1) | CA1300149C (en) |
| CH (1) | CH666688A5 (en) |
| DE (1) | DE3531004A1 (en) |
| DK (1) | DK157871C (en) |
| ES (1) | ES8604967A1 (en) |
| FI (1) | FI82468C (en) |
| FR (1) | FR2569698B1 (en) |
| GB (2) | GB8422029D0 (en) |
| HK (1) | HK6189A (en) |
| IE (1) | IE58522B1 (en) |
| IT (1) | IT1201459B (en) |
| LU (1) | LU86052A1 (en) |
| NL (1) | NL8502324A (en) |
| NO (1) | NO162071C (en) |
| OA (1) | OA08088A (en) |
| PT (1) | PT81054B (en) |
| SE (1) | SE462218B (en) |
| ZA (1) | ZA856088B (en) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8427218D0 (en) * | 1984-10-27 | 1984-12-05 | Scras | Pyridine derivatives |
| GB8808001D0 (en) * | 1988-04-06 | 1988-05-05 | Scras | Stereospecific preparative process for furol(3,4-c)pyridine derivatives |
| DE10323602A1 (en) * | 2003-05-19 | 2004-12-16 | Südzucker AG Mannheim/Ochsenfurt | Hard caramel for human consumption, contains hard caramel base and supported food color inhomogeneously distributed within hard caramel base |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ZA786269B (en) * | 1977-11-25 | 1979-10-31 | Scras | New pyridine derivative,its preparation and use |
| ZA842029B (en) * | 1983-04-05 | 1984-10-31 | Scras | Furo-(3,4-c)-pyridine derivatives preparation thereof and therapeutic compositions containing the same |
| GB2153824B (en) * | 1984-02-02 | 1987-04-01 | Scras | Furo-(3,4-c)-pyridine derivatives |
-
1984
- 1984-08-31 GB GB848422029A patent/GB8422029D0/en active Pending
-
1985
- 1985-08-12 GB GB08520169A patent/GB2163744B/en not_active Expired
- 1985-08-12 ZA ZA856088A patent/ZA856088B/en unknown
- 1985-08-19 SE SE8503869A patent/SE462218B/en not_active IP Right Cessation
- 1985-08-20 AR AR85301339A patent/AR241455A1/en active
- 1985-08-22 LU LU86052A patent/LU86052A1/en unknown
- 1985-08-22 CA CA000489219A patent/CA1300149C/en not_active Expired - Lifetime
- 1985-08-23 NL NL8502324A patent/NL8502324A/en not_active Application Discontinuation
- 1985-08-23 CH CH3653/85A patent/CH666688A5/en not_active IP Right Cessation
- 1985-08-26 BE BE0/215502A patent/BE903122A/en not_active IP Right Cessation
- 1985-08-28 FI FI853287A patent/FI82468C/en not_active IP Right Cessation
- 1985-08-29 AT AT0252985A patent/AT396590B/en not_active IP Right Cessation
- 1985-08-30 DK DK396085A patent/DK157871C/en not_active IP Right Cessation
- 1985-08-30 NO NO853418A patent/NO162071C/en unknown
- 1985-08-30 DE DE19853531004 patent/DE3531004A1/en active Granted
- 1985-08-30 JP JP60190033A patent/JPS6160688A/en active Granted
- 1985-08-30 IT IT22035/85A patent/IT1201459B/en active
- 1985-08-30 IE IE214385A patent/IE58522B1/en not_active IP Right Cessation
- 1985-08-30 ES ES546590A patent/ES8604967A1/en not_active Expired
- 1985-08-30 PT PT81054A patent/PT81054B/en not_active IP Right Cessation
- 1985-08-30 FR FR8512917A patent/FR2569698B1/en not_active Expired
- 1985-08-30 OA OA58669A patent/OA08088A/en unknown
-
1989
- 1989-01-19 HK HK61/89A patent/HK6189A/en not_active IP Right Cessation
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| NAL | Patent in force |
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