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SE8502780L - aziridine - Google Patents

aziridine

Info

Publication number
SE8502780L
SE8502780L SE8502780A SE8502780A SE8502780L SE 8502780 L SE8502780 L SE 8502780L SE 8502780 A SE8502780 A SE 8502780A SE 8502780 A SE8502780 A SE 8502780A SE 8502780 L SE8502780 L SE 8502780L
Authority
SE
Sweden
Prior art keywords
formula
image
group
aziridine
ch2ch2l
Prior art date
Application number
SE8502780A
Other languages
Swedish (sv)
Other versions
SE460604B (en
SE8502780D0 (en
Inventor
J Bradshaw
J W Clitherow
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of SE8502780L publication Critical patent/SE8502780L/en
Publication of SE8502780D0 publication Critical patent/SE8502780D0/en
Publication of SE460604B publication Critical patent/SE460604B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/52—Radicals substituted by nitrogen atoms not forming part of a nitro radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D203/00—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D203/04—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D203/06—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D203/08—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring nitrogen atom
    • C07D203/12—Radicals substituted by nitrogen atoms not forming part of a nitro radical

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Furan Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

The invention relates to a process for the preparation of ranitidine of the formula: <IMAGE> which is characterised in that a thiol of the formula: <IMAGE> is reacted with an alkylating agent of the formula: <IMAGE> in which R1 denotes the group -CH2CH2L, where L represents a leaving group, and R2 represents a hydrogen atom or R1 and R2, together with the nitrogen atom to which they are attached, form an ethyleneimino group.
SE8502780A 1980-01-08 1985-06-05 AZIRIDE DERIVATIVES AND PROCEDURES FOR ITS PREPARATION SE460604B (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB8000581 1980-01-08
GB8000580 1980-01-08
GB8039336 1980-12-08

Publications (3)

Publication Number Publication Date
SE8502780L true SE8502780L (en) 1985-06-05
SE8502780D0 SE8502780D0 (en) 1985-06-05
SE460604B SE460604B (en) 1989-10-30

Family

ID=27260837

Family Applications (2)

Application Number Title Priority Date Filing Date
SE8100074A SE449747B (en) 1980-01-08 1981-01-08 PROCEDURE FOR PREPARING N- / 2 - // 5 - / (DIMETHYLAMINO) METHYL / -2-FURANYLMETHYL / -TIO / ETHYL / N'-METHYL-2-NITRO-1,1-ETHENYAMINE (RANITIDINE)
SE8502780A SE460604B (en) 1980-01-08 1985-06-05 AZIRIDE DERIVATIVES AND PROCEDURES FOR ITS PREPARATION

Family Applications Before (1)

Application Number Title Priority Date Filing Date
SE8100074A SE449747B (en) 1980-01-08 1981-01-08 PROCEDURE FOR PREPARING N- / 2 - // 5 - / (DIMETHYLAMINO) METHYL / -2-FURANYLMETHYL / -TIO / ETHYL / N'-METHYL-2-NITRO-1,1-ETHENYAMINE (RANITIDINE)

Country Status (14)

Country Link
JP (1) JPH02167259A (en)
AR (1) AR225940A1 (en)
AT (1) AT376966B (en)
CH (1) CH650257A5 (en)
DE (1) DE3100364A1 (en)
DK (1) DK157865C (en)
ES (1) ES498389A0 (en)
FI (1) FI80450C (en)
FR (1) FR2473044A1 (en)
HU (1) HU182272B (en)
NL (1) NL8100068A (en)
PT (1) PT72320B (en)
SE (2) SE449747B (en)
YU (1) YU42372B (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3213509A1 (en) * 1982-04-10 1983-10-20 Basf Ag, 6700 Ludwigshafen N-SUBSTITUTED IMIDAZOLE DERIVATIVES, THEIR PRODUCTION, THE MEDICINES CONTAINING THEM AND THEIR USE
YU42819B (en) * 1982-11-22 1988-12-31 Lek Tovarna Farmacevtskih Process for preparing n-/2-///5-(dimethyl-amino)-methyl-2-furanyl/methyl/thio/ethyl-n'-methyl-2-nitro-1,1-ethene diamine
DE3343884A1 (en) * 1982-12-08 1984-06-14 Degussa Ag, 6000 Frankfurt Novel ethenediamine and guanidine derivatives
NL8303965A (en) * 1982-12-08 1984-07-02 Degussa NEW FOOD DIAMINE AND GUANIDINE DERIVATIVES; METHOD FOR PREPARING THEREOF MEDICINES CONTAINING THEM; METHOD FOR PREPARING SUCH MEDICINES; APPLICATION OF THE COMPOUNDS FOR THE PREPARATION OF MEDICINAL PRODUCTS AND IN MEDICINE.

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1565966A (en) * 1976-08-04 1980-04-23 Allen & Hanburys Ltd Aminoalkyl furan derivatives
IL56265A (en) 1977-12-28 1982-08-31 Om Lab Sa Process for preparing imidazolyl methylthio guanidine derivatives and a novel intermediate therefor
GR65283B (en) * 1977-12-30 1980-08-01 Crc Ricerca Chim Method for the alkyliosis of 4(5)-merka ptomethyl-imidazoles with aziridin derivatives
ZA792608B (en) * 1978-05-30 1980-06-25 Smith Kline French Lab Nitro compounds
NO811501L (en) * 1980-05-13 1981-11-16 Crc Ricerca Chim PROCEDURE FOR THE PREPARATION OF ETHENDIAMINE DERIVATIVES, AND INTERMEDIATES FOR THESE

Also Published As

Publication number Publication date
ATA3781A (en) 1984-06-15
FI80450C (en) 1990-06-11
AT376966B (en) 1985-01-25
DE3100364A1 (en) 1981-11-19
DK7181A (en) 1981-07-09
SE8100074L (en) 1981-07-09
SE460604B (en) 1989-10-30
DE3100364C2 (en) 1989-12-28
FR2473044B1 (en) 1984-04-13
ES8200673A1 (en) 1981-11-16
ES498389A0 (en) 1981-11-16
PT72320B (en) 1982-07-23
DK157865C (en) 1990-07-30
CH650257A5 (en) 1985-07-15
SE8502780D0 (en) 1985-06-05
DK157865B (en) 1990-02-26
HU182272B (en) 1983-12-28
YU42372B (en) 1988-08-31
FR2473044A1 (en) 1981-07-10
PT72320A (en) 1981-02-01
NL8100068A (en) 1981-08-03
SE449747B (en) 1987-05-18
FI80450B (en) 1990-02-28
YU2781A (en) 1983-06-30
FI810039L (en) 1981-07-09
AR225940A1 (en) 1982-05-14
JPH02167259A (en) 1990-06-27
JPH0346465B2 (en) 1991-07-16

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