SE8404118L - PREPARATION OF AEROSOL COMPOSITIONS - Google Patents
PREPARATION OF AEROSOL COMPOSITIONSInfo
- Publication number
- SE8404118L SE8404118L SE8404118A SE8404118A SE8404118L SE 8404118 L SE8404118 L SE 8404118L SE 8404118 A SE8404118 A SE 8404118A SE 8404118 A SE8404118 A SE 8404118A SE 8404118 L SE8404118 L SE 8404118L
- Authority
- SE
- Sweden
- Prior art keywords
- component
- preparation
- components
- under pressure
- chamber
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/12—Aerosols; Foams
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
- A61K9/1277—Preparation processes; Proliposomes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/009—Inhalators using medicine packages with incorporated spraying means, e.g. aerosol cans
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Dispersion Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Otolaryngology (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Medicinal Preparation (AREA)
- Cosmetics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
The invention relates to the preparation of aerosol compositions. The invention provides a method for the preparation of liposomes in which at least two separate components are brought together under pressure, a first component comprising water and a second component comprising a lipid material. The components are then passed as a mixture under pressure through a nozzle or other arrangement to produce an aerosol spray containing liposomes. In addition, at least one of the first or second components preferably includes a separate active material. The invention also provides a pack for use in preparing a liposomal aerosol comprising at least a first and a second chamber, one chamber containing a first component comprising water and the other chamber containing a second component comprising a lipid material, and one or both of the chambers and/or a third chamber including a propellant material. The pack also includes an arrangement for dispensing as a spray a mixture of the first and second components fed from their respective chambers under pressure developed by the propellant material or materials.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB838322178A GB8322178D0 (en) | 1983-08-17 | 1983-08-17 | Preparing aerosol compositions |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| SE8404118D0 SE8404118D0 (en) | 1984-08-16 |
| SE8404118L true SE8404118L (en) | 1985-02-18 |
| SE459471B SE459471B (en) | 1989-07-10 |
Family
ID=10547457
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE8404118A SE459471B (en) | 1983-08-17 | 1984-08-16 | LIPOSOMAL AEROSOL COMPOSITION AND PROCEDURES AND PACKAGING FOR PREPARATION THEREOF |
Country Status (22)
| Country | Link |
|---|---|
| JP (1) | JPS6089414A (en) |
| KR (1) | KR850001689A (en) |
| AT (1) | AT389993B (en) |
| AU (1) | AU569314B2 (en) |
| BE (1) | BE900375A (en) |
| CH (1) | CH667384B (en) |
| DE (1) | DE3430385A1 (en) |
| DK (1) | DK163479C (en) |
| ES (1) | ES535163A0 (en) |
| FI (1) | FI85214C (en) |
| FR (1) | FR2550706B1 (en) |
| GB (2) | GB8322178D0 (en) |
| GR (1) | GR80127B (en) |
| IE (1) | IE57537B1 (en) |
| IL (1) | IL72590A (en) |
| IT (1) | IT1175612B (en) |
| LU (1) | LU85512A1 (en) |
| NL (1) | NL8402514A (en) |
| NZ (1) | NZ209112A (en) |
| PT (1) | PT79104B (en) |
| SE (1) | SE459471B (en) |
| ZA (1) | ZA846064B (en) |
Families Citing this family (50)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3585967D1 (en) * | 1984-03-08 | 1992-06-11 | Phares Pharma Holland | LIPOSOME FORMING COMPOSITION. |
| GB8423436D0 (en) * | 1984-09-17 | 1984-10-24 | Riker Laboratories Inc | Preparation of liposomes |
| CA1260393A (en) * | 1984-10-16 | 1989-09-26 | Lajos Tarcsay | Liposomes of synthetic lipids |
| GB8502892D0 (en) * | 1985-02-05 | 1985-03-06 | Sterwin Ag | Aerosol composition |
| ATE78158T1 (en) * | 1985-05-22 | 1992-08-15 | Liposome Technology Inc | METHOD AND SYSTEM FOR INHALATION OF LIPOSOMES. |
| US5340587A (en) * | 1985-05-22 | 1994-08-23 | Liposome Technology, Inc. | Liposome/bronchodilator method & System |
| US5192528A (en) | 1985-05-22 | 1993-03-09 | Liposome Technology, Inc. | Corticosteroid inhalation treatment method |
| GB8522964D0 (en) * | 1985-09-17 | 1985-10-23 | Biocompatibles Ltd | Aerosol |
| EP0221821A3 (en) * | 1985-11-01 | 1988-01-27 | Centre National De La Recherche Scientifique (Cnrs) | New aerosol composition for in vivo imaging and therapy |
| IE63869B1 (en) * | 1986-11-06 | 1995-06-14 | Res Dev Foundation | Aerosols containing liposomes and method for their preparation |
| US4897256A (en) * | 1986-11-25 | 1990-01-30 | Abbott Laboratories | LHRH analog formulations |
| US5030442A (en) * | 1987-03-30 | 1991-07-09 | Liposome Technology, Inc. | Non-crystalline minoxidil composition |
| US4828837A (en) * | 1987-03-30 | 1989-05-09 | Liposome Technology, Inc. | Non-crystalline minoxidil composition, its production and application |
| JP2581920B2 (en) * | 1987-05-18 | 1997-02-19 | 有限会社野々川商事 | Cosmetics |
| FR2638639A1 (en) * | 1988-11-08 | 1990-05-11 | Parincos Parfumerie Cosmet Int | Composition and method for the production of oligolamellar liposomes for the purpose of application in cosmetology and topical dermatology |
| JPH03193714A (en) * | 1989-12-25 | 1991-08-23 | Kobayashi Kose Co Ltd | Aerosol-type cosmetic |
| DE4203306A1 (en) * | 1992-02-06 | 1993-08-12 | Ig Spruehtechnik Gmbh | ASTHMA OR PULMONAL AEROSOL PREPARATIONS WITH LECITHIN |
| DE59406065D1 (en) * | 1993-03-24 | 1998-07-02 | Ciba Geigy Ag | Process for the production of a liposome dispersion in the high pressure range |
| AU689786B2 (en) * | 1993-06-30 | 1998-04-09 | Genentech Inc. | Method for preparing liposomes |
| GB9409763D0 (en) * | 1994-05-16 | 1994-07-06 | Phares Pharma Holland | Liposome forming compositions |
| ES2111488B1 (en) * | 1996-01-17 | 1998-11-01 | Lucas Meyer S A | USE OF PROLIPOSOMES COMPOSITIONS IN THE DYE, WHITENING AND SOFTENING OF THE TEXTILE INDUSTRY AND PROCEDURE FOR THE PREPARATION OF DYE BANKS FROM THESE PROLIPOSOME COMPOSITIONS. |
| AU7454698A (en) * | 1997-06-06 | 1998-12-21 | Shionogi & Co., Ltd. | Improvement in medicament administration system |
| US20030044454A1 (en) * | 1998-06-30 | 2003-03-06 | Masaru Fukui | Compositions containing liposomes and/or emulsions and process for the preparation thereof |
| AU766703B2 (en) * | 1998-11-12 | 2003-10-23 | Frank G Pilkiewicz | An inhalation system |
| EP1839648A3 (en) * | 1998-11-12 | 2007-11-21 | Transave, Inc. | An inhalation system |
| US7879351B2 (en) | 2002-10-29 | 2011-02-01 | Transave, Inc. | High delivery rates for lipid based drug formulations, and methods of treatment thereof |
| HUE025491T2 (en) | 2002-10-29 | 2016-04-28 | Insmed Inc | Sustained release of antiinfectives |
| US7718189B2 (en) | 2002-10-29 | 2010-05-18 | Transave, Inc. | Sustained release of antiinfectives |
| WO2007049278A2 (en) * | 2005-10-26 | 2007-05-03 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | A method for preparing liposomes and uses thereof |
| HUE029994T2 (en) | 2005-12-08 | 2017-04-28 | Insmed Inc | Lipid-based preparations of antinfectants for the treatment of lung infections |
| JP4058108B2 (en) * | 2006-04-11 | 2008-03-05 | 株式会社バイオメディア | Method and apparatus for producing liposome dispersion |
| WO2008137717A1 (en) | 2007-05-04 | 2008-11-13 | Transave, Inc. | Compositions of multicationic drugs for reducing interactions with polyanionic biomolecules and methods and uses thereof |
| US9119783B2 (en) | 2007-05-07 | 2015-09-01 | Insmed Incorporated | Method of treating pulmonary disorders with liposomal amikacin formulations |
| US9333214B2 (en) | 2007-05-07 | 2016-05-10 | Insmed Incorporated | Method for treating pulmonary disorders with liposomal amikacin formulations |
| US9114081B2 (en) | 2007-05-07 | 2015-08-25 | Insmed Incorporated | Methods of treating pulmonary disorders with liposomal amikacin formulations |
| KR101271312B1 (en) | 2008-12-29 | 2013-06-04 | 에프게니 파블로프 그레베니코브 | Method for producing liposomal drugs and a device for producing a liposome |
| RU2470624C1 (en) * | 2011-08-25 | 2012-12-27 | Евгений Петрович Гребенников | Device for producing liposomal preparations |
| SI2852391T1 (en) | 2012-05-21 | 2022-04-29 | Insmed Incorporated | Lung infection management systems |
| RU2675859C2 (en) | 2012-11-29 | 2018-12-25 | Инсмед Инкорпорейтед | Stabilised vancomycin formulations |
| EP3104853B1 (en) | 2014-02-10 | 2019-10-02 | Respivant Sciences GmbH | Mast cell stabilizers treatment for systemic disorders |
| US20160367520A1 (en) | 2014-02-10 | 2016-12-22 | Patara Pharma, LLC | Mast cell stabilizers for lung disease treatment |
| AU2015258947B2 (en) | 2014-05-15 | 2020-04-09 | Insmed Incorporated | Methods for treating pulmonary non-tuberculous mycobacterial infections |
| WO2017027402A1 (en) | 2015-08-07 | 2017-02-16 | Patara Pharma, LLC | Methods for the treatment of systemic disorders treatable with mast cell stabilizers, including mast cell related disorders |
| WO2017027387A1 (en) | 2015-08-07 | 2017-02-16 | Patara Pharma, LLC | Methods for the treatment of mast cell related disorders with mast cell stabilizers |
| WO2018044942A1 (en) | 2016-08-31 | 2018-03-08 | Patara Pharma, LLC | Cromolyn compositions for treatment of chronic cough due to idiopathic pulmonary fibrosis |
| JP2019531308A (en) | 2016-10-07 | 2019-10-31 | レシュピファント サイエンシス ゲゼルシャフト ミット ベシュレンクター ハフトゥングRespivant Sciences Gmbh | Cromolyn composition for the treatment of pulmonary fibrosis |
| JP7008975B2 (en) * | 2017-08-31 | 2022-01-25 | クラシエホームプロダクツ株式会社 | Skin cosmetics |
| EP3773505A4 (en) | 2018-03-30 | 2021-12-22 | Insmed Incorporated | PROCESSES FOR THE CONTINUOUS MANUFACTURE OF LIPOSOMAL DRUG PRODUCTS |
| CA3098573A1 (en) | 2018-05-02 | 2019-11-07 | Insmed Incorporated | Methods for the manufacture of liposomal drug formulations |
| WO2022014899A1 (en) * | 2020-07-17 | 2022-01-20 | Kt&G Corporation | Pressurization device for aerosol generating article and aerosol generating system including the same |
Family Cites Families (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB780885A (en) * | 1955-05-03 | 1957-08-07 | Innoxa England Ltd | Foundation cream |
| GB993702A (en) * | 1961-11-10 | 1965-06-02 | Takeda Chemical Industries Ltd | An aerosol dispersing agent |
| DE1277210B (en) * | 1965-09-24 | 1968-09-12 | Revlon | Self-propelling mixtures |
| US3326416A (en) * | 1966-01-14 | 1967-06-20 | Du Pont | Apparatus for codispensing a plurality of liquids |
| US3325056A (en) * | 1966-02-23 | 1967-06-13 | Du Pont | Apparatus for codispensing a plurality of liquids |
| US3338479A (en) * | 1966-04-04 | 1967-08-29 | Leonard L Marraffino | Mixing head with secondary fluid adapted for connection with discharge means of primary fluid container |
| GB1287470A (en) * | 1968-11-25 | 1972-08-31 | Gillette Co | Pressurised dispensing package |
| US3594476A (en) * | 1969-05-12 | 1971-07-20 | Massachusetts Inst Technology | Submicron aqueous aerosols containing lecithin |
| NL7012832A (en) * | 1970-08-29 | 1972-03-02 | ||
| US3637114A (en) * | 1970-09-03 | 1972-01-25 | Philip Meshberg | Device for codispensing two materials |
| GB1372721A (en) * | 1971-01-16 | 1974-11-06 | Wilkinson Sword Ltd | Containers of antiseptics for the treatment of burns and scalds |
| DE2115926C3 (en) * | 1971-04-01 | 1978-05-03 | C.H. Boehringer Sohn, 6507 Ingelheim | 1 - (4-Hydroxy-3-dimethylaminosulfamidophenyI) -2-aminoether derivatives, process for their preparation and compositions containing them |
| US3997467A (en) * | 1971-11-26 | 1976-12-14 | Pharmacia Aktiebolag | Foam forming composition |
| DE2346730C3 (en) * | 1973-09-17 | 1980-10-16 | Carl Heyer Gmbh, Inhalationstechnik, 5427 Bad Ems | Device for aerosol treatment of people, animals, objects, substances and the like in a treatment room |
| LU70720A1 (en) * | 1974-08-12 | 1976-08-19 | ||
| US4073412A (en) * | 1976-06-03 | 1978-02-14 | Blue Cross Laboratories, Inc. | Emulsified cookware lubricant having freeze-thaw stability |
| GB1575343A (en) * | 1977-05-10 | 1980-09-17 | Ici Ltd | Method for preparing liposome compositions containing biologically active compounds |
| GB2001334B (en) * | 1977-07-19 | 1982-03-03 | Fisons Ltd | Pressurised aerosol formulation |
| FR2416008A1 (en) * | 1978-02-02 | 1979-08-31 | Oreal | LIPOSOME LYOPHILISATES |
| CH646390A5 (en) * | 1980-05-12 | 1984-11-30 | Polyfill Ag | Siphon. |
| DE3207289A1 (en) * | 1982-03-01 | 1983-09-15 | Perfect-Valois Ventil GmbH, 4600 Dortmund | DISPENSING VALVE FOR AEROSOL CAN |
| EP0100964A3 (en) * | 1982-07-31 | 1984-06-13 | Reifenrath, Rainer, Dr. | Pharmaceutical product for the treatment and prophylaxis of infections, cough and obstructive respiratory diseases, and process for preparing it |
| FR2543018B1 (en) * | 1983-03-22 | 1985-07-26 | Oreal | PROCESS FOR THE PREPARATION OF LIPID VESICLES BY SPRAYING SOLVENTS |
| CH664943A5 (en) * | 1983-08-16 | 1988-04-15 | Sterwin Ag | TWO-COMPONENT PACK. |
-
1983
- 1983-08-17 GB GB838322178A patent/GB8322178D0/en active Pending
-
1984
- 1984-08-03 NZ NZ209112A patent/NZ209112A/en unknown
- 1984-08-06 ZA ZA846064A patent/ZA846064B/en unknown
- 1984-08-06 IL IL72590A patent/IL72590A/en unknown
- 1984-08-10 AU AU31786/84A patent/AU569314B2/en not_active Ceased
- 1984-08-14 ES ES535163A patent/ES535163A0/en active Granted
- 1984-08-15 FI FI843223A patent/FI85214C/en not_active IP Right Cessation
- 1984-08-15 DE DE19843430385 patent/DE3430385A1/en not_active Withdrawn
- 1984-08-16 IE IE2121/84A patent/IE57537B1/en not_active IP Right Cessation
- 1984-08-16 JP JP59170982A patent/JPS6089414A/en active Pending
- 1984-08-16 AT AT0263684A patent/AT389993B/en not_active IP Right Cessation
- 1984-08-16 KR KR1019840004923A patent/KR850001689A/en not_active Withdrawn
- 1984-08-16 DK DK392884A patent/DK163479C/en not_active IP Right Cessation
- 1984-08-16 GB GB08420850A patent/GB2145107B/en not_active Expired
- 1984-08-16 NL NL8402514A patent/NL8402514A/en not_active Application Discontinuation
- 1984-08-16 GR GR80127A patent/GR80127B/en unknown
- 1984-08-16 SE SE8404118A patent/SE459471B/en not_active IP Right Cessation
- 1984-08-16 CH CH395884A patent/CH667384B/xx not_active IP Right Cessation
- 1984-08-17 LU LU85512A patent/LU85512A1/en unknown
- 1984-08-17 PT PT79104A patent/PT79104B/en not_active IP Right Cessation
- 1984-08-17 FR FR8412930A patent/FR2550706B1/fr not_active Expired
- 1984-08-17 BE BE0/213504A patent/BE900375A/en not_active IP Right Cessation
- 1984-08-17 IT IT22357/84A patent/IT1175612B/en active
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| NUG | Patent has lapsed |
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