SE8402551L - Cinnamoylmoranolin-derivat - Google Patents

Cinnamoylmoranolin-derivat

Info

Publication number: SE8402551L
Authority: SE; Sweden
Prior art keywords: cinnamoylmoranolin; derivatives; same; aralkylmoranoline; aralkenylmoranoline
Prior art date: 1978-05-03

Application number

SE8402551A

Other languages

English (en)

Other versions

SE8402551D0 (sv

SE451017B (sv

Inventor

S Matsumura

H Enomoto

Y Aoyagi

Y Yoshikuni

K Kura

M Yagi

I Shirahase

Original Assignee

Nippon Shinyaku Co Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1978-05-03

Filing date

1984-05-11

Publication date

1984-05-11

1978-05-03 Priority claimed from JP53053603A external-priority patent/JPS5943947B2/ja

1978-07-06 Priority claimed from JP8260678A external-priority patent/JPS5943948B2/ja

1978-09-29 Priority claimed from JP12066178A external-priority patent/JPS5943949B2/ja

1979-01-20 Priority claimed from JP571479A external-priority patent/JPS6026387B2/ja

1984-05-11 Application filed by Nippon Shinyaku Co Ltd filed Critical Nippon Shinyaku Co Ltd

1984-05-11 Publication of SE8402551L publication Critical patent/SE8402551L/sv

1984-05-11 Publication of SE8402551D0 publication Critical patent/SE8402551D0/sv

1987-08-24 Publication of SE451017B publication Critical patent/SE451017B/sv

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/40—Oxygen atoms
- C07D211/44—Oxygen atoms attached in position 4
- C07D211/46—Oxygen atoms attached in position 4 having a hydrogen atom as the second substituent in position 4

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Hydrogenated Pyridines (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

SE8402551A 1978-05-03 1984-05-11 Cinnamylmoranolin-derivat SE451017B (sv)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
JP53053603A JPS5943947B2 (ja)	1978-05-03	1978-05-03	Ｎ−置換モラノリン誘導体
JP8260678A JPS5943948B2 (ja)	1978-07-06	1978-07-06	置換モラノリン誘導体
JP12066178A JPS5943949B2 (ja)	1978-09-29	1978-09-29	モラノリンのｎ−置換誘導体
JP571479A JPS6026387B2 (ja)	1979-01-20	1979-01-20	シンナミルモラノリン誘導体

Publications (3)

Publication Number	Publication Date
SE8402551L true SE8402551L (sv)	1984-05-11
SE8402551D0 SE8402551D0 (sv)	1984-05-11
SE451017B SE451017B (sv)	1987-08-24

Family

ID=27454348

Family Applications (4)

Application Number	Title	Priority Date	Filing Date
SE7903817A SE436874B (sv)	1978-05-03	1979-05-02	N-substituerade moranolinderivat
SE8402549A SE451015B (sv)	1978-05-03	1984-05-11	Substituerade moranolinderivat
SE8402551A SE451017B (sv)	1978-05-03	1984-05-11	Cinnamylmoranolin-derivat
SE8402550A SE451016B (sv)	1978-05-03	1984-05-11	N-substituerade derivat av moranolin

Family Applications Before (2)

Application Number	Title	Priority Date	Filing Date
SE7903817A SE436874B (sv)	1978-05-03	1979-05-02	N-substituerade moranolinderivat
SE8402549A SE451015B (sv)	1978-05-03	1984-05-11	Substituerade moranolinderivat

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
SE8402550A SE451016B (sv)	1978-05-03	1984-05-11	N-substituerade derivat av moranolin

Country Status (9)

Country	Link
US (1)	US4533668A (sv)
CH (1)	CH642629A5 (sv)
DE (1)	DE2915037C3 (sv)
DK (1)	DK151623C (sv)
FR (1)	FR2424910A1 (sv)
GB (1)	GB2020278B (sv)
IT (1)	IT1116820B (sv)
NL (1)	NL175820C (sv)
SE (4)	SE436874B (sv)

Families Citing this family (40)

* Cited by examiner, † Cited by third party
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NO154918C (no) *	1977-08-27	1987-01-14	Bayer Ag	Analogifremgangsmaate til fremstilling av terapeutisk aktive derivater av 3,4,5-trihydroksypiperidin.
DE2925943A1 (de) *	1979-06-27	1981-01-29	Bayer Ag	1-alkadien-2,4-yl-2-hydroxymethyl3,4,5-trihydroxypiperidine, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
DE2942365A1 (de) *	1979-10-19	1981-05-14	Bayer Ag, 5090 Leverkusen	2-hydroxyalkyl-3,4,5-trihydroxy-(pi)-peridine, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
DE3007078A1 (de) *	1980-02-26	1981-09-10	Bayer Ag, 5090 Leverkusen	Neue derivate von 3,4,5-trihydroxypiperidin, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel sowie in der tierernaehrung
JP2504000B2 (ja) *	1986-09-02	1996-06-05	日本新薬株式会社	グルコシルモラノリン誘導体
JPS6461459A (en) *	1987-08-28	1989-03-08	Nippon Shinyaku Co Ltd	Moranoline derivative
GB8827701D0 (en) *	1987-12-09	1988-12-29	Nippon Shinyaku Co Ltd	Thrombolytic &c compositions
US5192772A (en) *	1987-12-09	1993-03-09	Nippon Shinyaku Co. Ltd.	Therapeutic agents
US4985445A (en) *	1988-02-12	1991-01-15	Meiji Seika Kaisha, Ltd.	Cancer cell metastasis inhibitors and novel compounds
EP0350012A3 (en) *	1988-07-08	1990-09-05	Meiji Seika Kaisha Ltd.	Antiviral composition
US5258518A (en) *	1992-04-01	1993-11-02	G. D. Searle & Co.	2-substituted tertiary carbinol derivatives of deoxynojirimycin
ATE142201T1 (de) *	1992-04-01	1996-09-15	Searle & Co	2- und 3-amino und azidoderivate von 1,5- iminozuckern als antivirale arzneimittel
US5268482A (en) *	1992-04-01	1993-12-07	G. D. Searle & Co.	2- and 3-sulfur derivatives of 1,5-iminosugars
US5331096A (en) *	1992-04-01	1994-07-19	G. D. Searle & Co.	2- and 3-sulfur derivatives of 1,5-iminosugars
US5206251A (en) *	1992-04-01	1993-04-27	G. D. Searle & Co.	2- and 3- amino and azido derivatives of 1,5-iminosugars
US5216168A (en) *	1992-04-01	1993-06-01	G. D. Searle & Co.	2- and 3- amino and azido derivatives of 1,5-iminosugars
US5342951A (en) *	1992-04-01	1994-08-30	G.D. Searle & Co.	2- and 3-sulfur derivatives of 1,5-iminosugars
US5798366A (en) *	1993-05-13	1998-08-25	Monsanto Company	Method for treatment of CNS-involved lysosomal storage diseases
US6291657B1 (en) *	1993-05-13	2001-09-18	Monsanto Company	Deoxygalactonojirimycin derivatives
US5399567A (en) *	1993-05-13	1995-03-21	Monsanto Company	Method of treating cholera
US20030100532A1 (en)	1997-02-14	2003-05-29	Gary S. Jacob	Use of n-substituted-1,5-dideoxy-1,5-imino-d-glucitol compounds in combination therapy for treating hepatitis virus infections
ES2216327T3 (es)	1997-11-10	2004-10-16	G.D. SEARLE & CO.	Uso de iminoazucares alquilados para tratar la resistencia a multiples a farmacos.
US6689759B1 (en)	1998-02-12	2004-02-10	G. D. Searle & Co.	Methods of Treating hepatitis virus infections with N-substituted-1,5-dideoxy-1,5-imino-d-glucitol compounds in combination therapy
BR9907882A (pt)	1998-02-12	2000-10-17	Searle & Co	Uso de compostos de 1,5-didesóxi-1,5-imino-d-glucitol n-substituìdos para o tratamento de infecções de vìrus de hepatite
WO2001008672A2 (en)	1999-02-12	2001-02-08	G.D. Searle & Co.	Glucamine compounds for treating hepatitis virus infections
DE60039729D1 (de) *	1999-02-12	2008-09-11	United Therapeutics Corp	N-(8,8,8-Trifluorooctyl)-1,5-dideoxy-1,5-imino-D-glucitol zur Behandlung von Hepatitis-Virus-Infektionen
WO2001060366A1 (en) *	2000-02-14	2001-08-23	Pharmacia Corporation	Use of n-substituted-1,5-dideoxy-1,5-imino-d-glucitol compounds for treating hepatitis virus infections
US8003617B2 (en) *	2004-11-10	2011-08-23	Genzyme Corporation	Methods of treating diabetes mellitus
AT502145B1 (de) *	2005-03-24	2012-01-15	Univ Graz Tech	Glycosidase-hemmendes iminoalditol
US8716327B2 (en)	2006-05-09	2014-05-06	Genzyme Corporation	Methods of treating fatty liver disease
EP2023927B1 (en) *	2006-05-24	2015-02-25	United Therapeutics Corporation	Deoxynojirimycin and d-arabinitol analogs and methods of using
US8097728B2 (en) *	2007-04-30	2012-01-17	Philadelphia Health & Education Corporation	Iminosugar compounds with antiflavirus activity
EP2594563B1 (en)	2007-05-31	2018-07-18	Genzyme Corporation	2-acylaminopropanol-type glucosylceramide synthase inhibitors
WO2009045503A1 (en) *	2007-10-05	2009-04-09	Genzyme Corporation	Method of treating polycystic kidney diseases with ceramide derivatives
JP2011529500A (ja)	2008-07-28	2011-12-08	ジェンザイムコーポレーション	虚脱性糸球体症および他の糸球体疾患の処置のためのグルコシルセラミドシンターゼ阻害
CA2738768C (en)	2008-10-03	2017-10-31	Genzyme Corporation	2-acylaminopropoanol-type glucosylceramide synthase inhibitors
BR112018072298A2 (pt)	2016-05-02	2019-02-12	Florida State University Research Foundation, Inc.	tratamento de infecções pelo vírus da zika usando inibidores da alfa-glicosidase
WO2021168483A2 (en)	2020-02-21	2021-08-26	Florida State University Research Foundation, Inc.	Treatment of human coronavirus infections using alpha-glucosidase glycoprotein processing inhibitors
BR112022022548A2 (pt) *	2020-05-07	2023-01-17	Alectos Therapeutics Inc	Inibidores de glucosilceramidase não lisossômicos e usos dos mesmos
US12528773B2 (en)	2020-05-07	2026-01-20	Alectos Therapeutics Inc.	Non-lysosomal glucosylceramidase inhibitors and uses thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS5282710A (en) *	1975-12-29	1977-07-11	Nippon Shinyaku Co Ltd	Extraction of effective drug component from mulberry
DE2735316C3 (de) *	1977-08-05	1981-01-29	Basf Ag, 6700 Ludwigshafen	Verfahren zur Herstellung von nadeiförmigen, ferrimagnetischen Eisenoxiden

1979
- 1979-03-21 GB GB7909865A patent/GB2020278B/en not_active Expired
- 1979-04-12 DE DE2915037A patent/DE2915037C3/de not_active Expired
- 1979-04-25 FR FR7910559A patent/FR2424910A1/fr active Granted
- 1979-04-27 US US06/033,839 patent/US4533668A/en not_active Expired - Lifetime
- 1979-05-01 DK DK178379A patent/DK151623C/da not_active IP Right Cessation
- 1979-05-02 SE SE7903817A patent/SE436874B/sv not_active IP Right Cessation
- 1979-05-02 IT IT48904/79A patent/IT1116820B/it active
- 1979-05-02 NL NLAANVRAGE7903421,A patent/NL175820C/xx not_active IP Right Cessation
- 1979-05-03 CH CH415879A patent/CH642629A5/de not_active IP Right Cessation
1984
- 1984-05-11 SE SE8402549A patent/SE451015B/sv not_active IP Right Cessation
- 1984-05-11 SE SE8402551A patent/SE451017B/sv not_active IP Right Cessation
- 1984-05-11 SE SE8402550A patent/SE451016B/sv not_active IP Right Cessation

Also Published As

Publication number	Publication date
SE8402551D0 (sv)	1984-05-11
GB2020278B (en)	1983-02-23
DK151623C (da)	1988-07-18
NL175820B (nl)	1984-08-01
IT7948904A0 (it)	1979-05-02
GB2020278A (en)	1979-11-14
SE451016B (sv)	1987-08-24
SE436874B (sv)	1985-01-28
DE2915037A1 (de)	1979-11-08
SE451017B (sv)	1987-08-24
SE8402549D0 (sv)	1984-05-11
NL7903421A (nl)	1979-11-06
FR2424910A1 (fr)	1979-11-30
IT1116820B (it)	1986-02-10
SE8402550D0 (sv)	1984-05-11
SE451015B (sv)	1987-08-24
CH642629A5 (de)	1984-04-30
DE2915037B2 (de)	1981-01-29
DE2915037C3 (de)	1981-11-05
SE8402550L (sv)	1984-05-11
SE7903817L (sv)	1979-11-04
NL175820C (nl)	1985-01-02
US4533668A (en)	1985-08-06
DK151623B (da)	1987-12-21
FR2424910B1 (sv)	1981-12-11
SE8402549L (sv)	1984-05-11
DK178379A (da)	1979-11-04

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Legal Events

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1995-01-31	NUG	Patent has lapsed	Ref document number: 8402551-9 Effective date: 19941210 Format of ref document f/p: F
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